Prediction of Drug-Induced Liver Injury in Micropatterned Co-cultures Containing iPSC-Derived Human Hepatocytes von Ware, Brenton R, Berger, Dustin R, Khetani, Salman R

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Enhancing the functional maturity of induced pluripotent stem cell–derived human hepatocytes by controlled presentation of cell–cell interactions in vitro von Berger, Dustin R., Ware, Brenton R., Davidson, Matthew D., Allsup, Samuel R., Khetani, Salman R.

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Advances in Engineered Liver Models for Investigating Drug-Induced Liver Injury von Lin, Christine, Khetani, Salman R.

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Meeting the challenge of predicting hepatic clearance of compounds slowly metabolized by cytochrome P450 using a novel hepatocyte model, HepatoPac von Chan, Tom S, Yu, Hongbin, Moore, Amanda, Khetani, Salman R, Kehtani, Salman R, Tweedie, Donald

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Long-term exposure to abnormal glucose levels alters drug metabolism pathways and insulin sensitivity in primary human hepatocytes von Davidson, Matthew D., Ballinger, Kimberly R., Khetani, Salman R.

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Establishment of a Hepatocyte-Kupffer Cell Coculture Model for Assessment of Proinflammatory Cytokine Effects on Metabolizing Enzymes and Drug Transporters von Nguyen, Theresa V, Ukairo, Okechukwu, Khetani, Salman R, McVay, Michael, Kanchagar, Chitra, Seghezzi, Wolfgang, Ayanoglu, Gulesi, Irrechukwu, Onyi, Evers, Raymond

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Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens von March, Sandra, Ramanan, Vyas, Trehan, Kartik, Ng, Shengyong, Galstian, Ani, Gural, Nil, Scull, Margaret A, Shlomai, Amir, Mota, Maria M, Fleming, Heather E, Khetani, Salman R, Rice, Charles M, Bhatia, Sangeeta N

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Hepatitis C Virus Infection Induces Autocrine Interferon Signaling by Human Liver Endothelial Cells and Release of Exosomes, Which Inhibits Viral Replication von Giugliano, Silvia, Kriss, Michael, Golden-Mason, Lucy, Dobrinskikh, Evgenia, Stone, Amy E.L, Soto-Gutierrez, Alejandro, Mitchell, Angela, Khetani, Salman R, Yamane, Daisuke, Stoddard, Mark, Li, Hui, Shaw, George M, Edwards, Michael G, Lemon, Stanley M, Gale, Michael, Shah, Vijay H, Rosen, Hugo R

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A Cell Culture Platform to Maintain Long-term Phenotype of Primary Human Hepatocytes and Endothelial Cells von Ware, Brenton R, Durham, Mitchell J, Monckton, Chase P, Khetani, Salman R

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Assessment of a Micropatterned Hepatocyte Coculture System to Generate Major Human Excretory and Circulating Drug Metabolites von WEIWEI WANG, Wendy, KHETANI, Salman R, KRZYZEWSKI, Stacy, DUIGNAN, David B, OBACH, R. Scott

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Real-time imaging of hepatitis C virus infection using a fluorescent cell-based reporter system von Jones, Christopher T, Catanese, Maria Teresa, Law, Lok Man J, Khetani, Salman R, Syder, Andrew J, Ploss, Alexander, Oh, Thomas S, Schoggins, John W, MacDonald, Margaret R, Bhatia, Sangeeta N, Rice, Charles M

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Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures von Ploss, Alexander, Khetani, Salman R, Jones, Christopher T, Syder, Andrew J, Trehan, Kartik, Gaysinskaya, Valeriya A, Mu, Kathy, Ritola, Kimberly, Rice, Charles M, Bhatia, Sangeeta N

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Microscale Collagen and Fibroblast Interactions Enhance Primary Human Hepatocyte Functions in Three-Dimensional Models von Kukla, David A., Crampton, Alexandra L., Wood, David K., Khetani, Salman R.

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Pluripotent Stem Cell-Derived Human Liver Organoids Enter the Realm of High-Throughput Drug Screening von Khetani, Salman R.

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Bioengineered Liver Models for Drug Testing and Cell Differentiation Studies von Underhill, Gregory H, Khetani, Salman R

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Emerging trends in modeling human liver disease in vitro von Underhill, Gregory H., Khetani, Salman R.

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Latest impact of engineered human liver platforms on drug development von Monckton, Chase P., Brown, Grace E., Khetani, Salman R.

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Microscale culture of human liver cells for drug development von Khetani, Salman R, Bhatia, Sangeeta N

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A human iPSC-derived hepatocyte screen identifies compounds that inhibit production of Apolipoprotein B von Liu, Jui-Tung, Doueiry, Caren, Jiang, Yu-lin, Blaszkiewicz, Josef, Lamprecht, Mary Paige, Heslop, James A., Peterson, Yuri K., Carten, Juliana Debrito, Traktman, Paula, Yuan, Yang, Khetani, Salman R., Twal, Waleed O., Duncan, Stephen A.

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Engineered Liver Platforms for Different Phases of Drug Development von Ware, Brenton R, Khetani, Salman R

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