The role of cancer-associated fibroblasts, solid stress and other microenvironmental factors in tumor progression and therapy resistance von Kharaishvili, Gvantsa, Simkova, Dana, Bouchalova, Katerina, Gachechiladze, Mariam, Narsia, Nato, Bouchal, Jan

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Epithelial-Mesenchymal Transition: A Fundamental Cellular and Microenvironmental Process in Benign and Malignant Prostate Pathologies von Goncharov, Aviv Philip, Vashakidze, Nino, Kharaishvili, Gvantsa

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Cancer-associated fibroblasts promote prostate tumor growth and progression through upregulation of cholesterol and steroid biosynthesis von Neuwirt, Hannes, Bouchal, Jan, Kharaishvili, Gvantsa, Ploner, Christian, Joehrer, Karin, Pitterl, Florian, Weber, Anja, Klocker, Helmut, Eder, Iris E.

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Skp2 and Slug Are Coexpressed in Aggressive Prostate Cancer and Inhibited by Neddylation Blockade von Mickova, Alena, Kharaishvili, Gvantsa, Kurfurstova, Daniela, Gachechiladze, Mariam, Kral, Milan, Vacek, Ondrej, Pokryvkova, Barbora, Mistrik, Martin, Soucek, Karel, Bouchal, Jan

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High Skp2 expression is associated with a mesenchymal phenotype and increased tumorigenic potential of prostate cancer cells von Šimečková, Šárka, Kahounová, Zuzana, Fedr, Radek, Remšík, Ján, Slabáková, Eva, Suchánková, Tereza, Procházková, Jiřina, Bouchal, Jan, Kharaishvili, Gvantsa, Král, Milan, Beneš, Petr, Souček, Karel

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Collagen triple helix repeat containing 1 protein, periostin and versican in primary and metastatic breast cancer: an immunohistochemical study von Kharaishvili, Gvantsa, Cizkova, Magdalena, Bouchalova, Katerina, Mgebrishvili, Giorgi, Kolar, Zdenek, Bouchal, Jan

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Trop-2 plasticity is controlled by epithelial-to-mesenchymal transition von Remšík, Ján, Binó, Lucia, Kahounová, Zuzana, Kharaishvili, Gvantsa, Šimečková, Šárka, Fedr, Radek, Kučírková, Tereza, Lenárt, Sára, Muresan, Ximena Maria, Slabáková, Eva, Knopfová, Lucia, Bouchal, Jan, Král, Milan, Beneš, Petr, Souček, Karel

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Cisplatin or LA-12 enhance killing effects of TRAIL in prostate cancer cells through Bid-dependent stimulation of mitochondrial apoptotic pathway but not caspase-10 von Vondálová Blanářová, Olga, Šafaříková, Barbora, Herůdková, Jarmila, Krkoška, Martin, Tománková, Silvie, Kahounová, Zuzana, Anděra, Ladislav, Bouchal, Jan, Kharaishvili, Gvantsa, Král, Milan, Sova, Petr, Kozubík, Alois, Hyršlová Vaculová, Alena

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Androgen Depletion Induces Senescence in Prostate Cancer Cells through Down-regulation of Skp2 von Pernicová, Zuzana, Slabáková, Eva, Kharaishvili, Gvantsa, Bouchal, Jan, Král, Milan, Kunická, Zuzana, Machala, Miroslav, Kozubík, Alois, Součcek, Karel

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Glycoprotein asporin as a novel player in tumour microenvironment and cancer progression von Simkova, Dana, Kharaishvili, Gvantsa, Slabakova, Eva, Murray, Paul G, Bouchal, Jan

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The dual role of asporin in breast cancer progression von Simkova, Dana, Kharaishvili, Gvantsa, Korinkova, Gabriela, Ozdian, Tomas, Suchánková-Kleplová, Tereza, Soukup, Tomas, Krupka, Michal, Galandakova, Adela, Dzubak, Petr, Janikova, Maria, Navratil, Jiri, Kahounova, Zuzana, Soucek, Karel, Bouchal, Jan

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The fibroblast surface markers FAP, anti‐fibroblast, and FSP are expressed by cells of epithelial origin and may be altered during epithelial‐to‐mesenchymal transition von Kahounová, Zuzana, Kurfürstová, Daniela, Bouchal, Jan, Kharaishvili, Gvantsa, Navrátil, Jiří, Remšík, Ján, Šimečková, Šárka, Študent, Vladimír, Kozubík, Alois, Souček, Karel

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Abstract A006: Skp2 associates with Slug and androgen receptor in aggressive prostate cancer von Bouchal, Jan, Kharaishvili, Gvantsa, Mickova, Alena, Gachechiladze, Mariam, Burdova, Alena, Mistrik, Martin, Kral, Milan, Gyorffy, Balazs, Kolar, Zdenek

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Abstract B084: Trop-2 plasticity is driven by epithelial-to-mesenchymal transition in prostate cancer cells von Remšík, Ján, Binó, Lucia, Kahounová, Zuzana, Kharaishvili, Gvantsa, Simeckova, Sarka, Fedr, Radek, Nehybova, Tereza, Slabáková, Eva, Knopfová, Lucia, Bouchal, Jan, Kral, Milan, Benes, Petr, Soucek, Karel

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The AR/NCOA1 axis regulates prostate cancer migration by involvement of PRKD1 von Luef, Birgit, Handle, Florian, Kharaishvili, Gvantsa, Hager, Martina, Rainer, Johannes, Janetschek, Günter, Hruby, Stephan, Englberger, Christine, Bouchal, Jan, Santer, Frédéric R, Culig, Zoran

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Advantages and limitations of 3D organoids and ex vivo tumor tissue culture in personalized medicine for prostate cancer von Mičková, Alena, Morong, Martin, Levková, Monika, Kurfürstová, Daniela, Kharaishvili, Gvantsa, Überall, Ivo, Študent, Vladimír, Drápela, Stanislav, Souček, Karel, Bouchal, Jan

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BCL2 is an independent predictor of outcome in basal-like triple-negative breast cancers treated with adjuvant anthracycline-based chemotherapy von Bouchalova, Katerina, Svoboda, Marek, Kharaishvili, Gvantsa, Vrbkova, Jana, Bouchal, Jan, Trojanec, Radek, Koudelakova, Vladimira, Radova, Lenka, Cwiertka, Karel, Hajduch, Marian, Kolar, Zdenek

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Sphingosine kinase-1 predicts overall survival outcomes in non-small cell lung cancer patients treated with carboplatin and navelbine von Gachechiladze, Mariam, Tichý, Tomáš, Kolek, Vítězslav, Grygárková, Ivona, Klein, Jiří, Mgebrishvili, Giorgi, Kharaishvili, Gvantsa, Janíková, Mária, Smičková, Petra, Cierna, Lucia, Pitson, Stuart, Maddelein, Marie-Lise, Cuvillier, Olivier, Škarda, Jozef

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The role of high cell density in the promotion of neuroendocrine transdifferentiation of prostate cancer cells von Pernicová, Zuzana, Slabáková, Eva, Fedr, Radek, Šimečková, Šárka, Jaroš, Josef, Suchánková, Tereza, Bouchal, Jan, Kharaishvili, Gvantsa, Král, Milan, Kozubík, Alois, Souček, Karel

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Opposite regulation of MDM2 and MDMX expression in acquisition of mesenchymal phenotype in benign and cancer cells von Slabáková, Eva, Kharaishvili, Gvantsa, Smějová, Monika, Pernicová, Zuzana, Suchánková, Tereza, Remšík, Ján, Lerch, Stanislav, Straková, Nicol, Bouchal, Jan, Král, Milan, Culig, Zoran, Kozubík, Alois, Souček, Karel

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