CDK4/6 and autophagy inhibitors synergistically induce senescence in Rb positive cytoplasmic cyclin E negative cancers von Vijayaraghavan, Smruthi, Karakas, Cansu, Doostan, Iman, Chen, Xian, Bui, Tuyen, Yi, Min, Raghavendra, Akshara S., Zhao, Yang, Bashour, Sami I., Ibrahim, Nuhad K., Karuturi, Meghan, Wang, Jing, Winkler, Jeffrey D., Amaravadi, Ravi K., Hunt, Kelly K., Tripathy, Debu, Keyomarsi, Khandan

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Synthetic Lethality of PARP Inhibitors in Combination with MYC Blockade Is Independent of BRCA Status in Triple-Negative Breast Cancer von Carey, Jason P W, Karakas, Cansu, Bui, Tuyen, Chen, Xian, Vijayaraghavan, Smruthi, Zhao, Yang, Wang, Jing, Mikule, Keith, Litton, Jennifer K, Hunt, Kelly K, Keyomarsi, Khandan

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Role of cell cycle in mediating sensitivity to radiotherapy von Pawlik, Timothy M., Keyomarsi, Khandan

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Enhancer transcription reveals subtype-specific gene expression programs controlling breast cancer pathogenesis von Franco, Hector L, Nagari, Anusha, Malladi, Venkat S, Li, Wenqian, Xi, Yuanxin, Richardson, Dana, Allton, Kendra L, Tanaka, Kaori, Li, Jing, Murakami, Shino, Keyomarsi, Khandan, Bedford, Mark T, Shi, Xiaobing, Li, Wei, Barton, Michelle C, Dent, Sharon Y R, Kraus, W Lee

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Cell cycle arrest induces lipid droplet formation and confers ferroptosis resistance von Lee, Hyemin, Horbath, Amber, Kondiparthi, Lavanya, Meena, Jitendra Kumar, Lei, Guang, Dasgupta, Shayani, Liu, Xiaoguang, Zhuang, Li, Koppula, Pranavi, Li, Mi, Mahmud, Iqbal, Wei, Bo, Lorenzi, Philip L., Keyomarsi, Khandan, Poyurovsky, Masha V., Olszewski, Kellen, Gan, Boyi

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CDK4/6 Inhibitors Sensitize Rb-positive Sarcoma Cells to Wee1 Kinase Inhibition through Reversible Cell-Cycle Arrest von Francis, Ashleigh M, Alexander, Angela, Liu, Yanna, Vijayaraghavan, Smruthi, Low, Kwang Hui, Yang, Dong, Bui, Tuyen, Somaiah, Neeta, Ravi, Vinod, Keyomarsi, Khandan, Hunt, Kelly K

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Cyclin E Overexpression Sensitizes Triple-Negative Breast Cancer to Wee1 Kinase Inhibition von Chen, Xian, Low, Kwang-Huei, Alexander, Angela, Jiang, Yufeng, Karakas, Cansu, Hess, Kenneth R, Carey, Jason P W, Bui, Tuyen N, Vijayaraghavan, Smruthi, Evans, Kurt W, Yi, Min, Ellis, D Christian, Cheung, Kwok-Leung, Ellis, Ian O, Fu, Siqing, Meric-Bernstam, Funda, Hunt, Kelly K, Keyomarsi, Khandan

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AXL Inhibition Suppresses the DNA Damage Response and Sensitizes Cells to PARP Inhibition in Multiple Cancers von Balaji, Kavitha, Vijayaraghavan, Smruthi, Diao, Lixia, Tong, Pan, Fan, Youhong, Carey, Jason Pw, Bui, Tuyen N, Warner, Steve, Heymach, John V, Hunt, Kelly K, Wang, Jing, Byers, Lauren Averett, Keyomarsi, Khandan

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Specific, reversible G1 arrest by UCN-01 in vivo provides cytostatic protection of normal cells against cytotoxic chemotherapy in breast cancer von Mull, Benjamin B., Livingston, J. Andrew, Patel, Nalini, Bui, Tuyen, Hunt, Kelly K., Keyomarsi, Khandan

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PAF-Wnt signaling-induced cell plasticity is required for maintenance of breast cancer cell stemness von Wang, Xin, Jung, Youn-Sang, Jun, Sohee, Lee, Sunhye, Wang, Wenqi, Schneider, Andrea, Sun Oh, Young, Lin, Steven H., Park, Bum-Joon, Chen, Junjie, Keyomarsi, Khandan, Park, Jae-Il

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Cytoplasmic Cyclin E Mediates Resistance to Aromatase Inhibitors in Breast Cancer von Doostan, Iman, Karakas, Cansu, Kohansal, Mehrnoosh, Low, Kwang-Hui, Ellis, Matthew J, Olson, Jr, John A, Suman, Vera J, Hunt, Kelly K, Moulder, Stacy L, Keyomarsi, Khandan

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Histone modification profiling in breast cancer cell lines highlights commonalities and differences among subtypes von Xi, Yuanxin, Shi, Jiejun, Li, Wenqian, Tanaka, Kaori, Allton, Kendra L, Richardson, Dana, Li, Jing, Franco, Hector L, Nagari, Anusha, Malladi, Venkat S, Coletta, Luis Della, Simper, Melissa S, Keyomarsi, Khandan, Shen, Jianjun, Bedford, Mark T, Shi, Xiaobing, Barton, Michelle C, Kraus, W Lee, Li, Wei, Dent, Sharon Y R

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Cytoplasmic Cyclin E Predicts Recurrence in Patients with Breast Cancer von Hunt, Kelly K, Karakas, Cansu, Ha, Min Jin, Biernacka, Anna, Yi, Min, Sahin, Aysegul A, Adjapong, Opoku, Hortobagyi, Gabriel N, Bondy, Melissa, Thompson, Patricia, Cheung, Kwok Leung, Ellis, Ian O, Bacus, Sarah, Symmans, W Fraser, Do, Kim-Anh, Keyomarsi, Khandan

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Synchronization of the cell cycle using Lovastatin von JavanMoghadam-Kamrani, Sonia, Keyomarsi, Khandan

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LMW cyclin E and its novel catalytic partner CDK5 are therapeutic targets and prognostic biomarkers in salivary gland cancers von Lulla, Amriti R., Akli, Said, Karakas, Cansu, Ha, Min Jin, Fowlkes, Natalie W., Mitani, Yoshitsugu, Bui, Tuyen, Wang, Jing, Rao, Xiayu, Hunt, Kelly K., Meijer, Laurent, El-Naggar, Adel K., Keyomarsi, Khandan

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Phase I trial of hydroxychloroquine to enhance palbociclib and letrozole efficacy in ER+/HER2− breast cancer von Raghavendra, Akshara Singareeka, Kettner, Nicole M., Kwiatkowski, Danielle, Damodaran, Senthil, Wang, Yan, Ramirez, David, Gombos, Dan S., Hunt, Kelly K., Shen, Yu, Keyomarsi, Khandan, Tripathy, Debu

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Autophagy : A Novel Mechanism of Synergistic Cytotoxicity between Doxorubicin and Roscovitine in a Sarcoma Model von LAMBERT, Laura A, NA QIAO, HUNT, Kelly K, LAMBERT, Donald H, MILLS, Gordon B, MEIJER, Laurent, KEYOMARSI, Khandan

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Integrative Analysis of Cyclin Protein Levels Identifies Cyclin B1 as a Classifier and Predictor of Outcomes in Breast Cancer von AGARWAL, Roshan, GONZALEZ-ANGULO, Ana-Maria, WEN LIN KUO, SORLIE, Therese, SAHIN, Aysegul, VALERO, Vicente, KEYOMARSI, Khandan, GRAY, Joe W, BORRESEN-DALE, Anne-Lise, MILLS, Gordon B, HENNESSY, Bryan T, MYHRE, Simen, CAREY, Mark, LEE, Ju-Seog, OVERGAARD, Jens, ALSNER, Jan, STEMKE-HALE, Katherine, LLUCH, Ana, NEVE, Richard M

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EVI1 splice variants modulate functional responses in ovarian cancer cells von Dutta, Punashi, Bui, Tuyen, Bauckman, Kyle A., Keyomarsi, Khandan, Mills, Gordon B., Nanjundan, Meera

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Atypical PKCι Contributes to Poor Prognosis through Loss of Apical-Basal Polarity and Cyclin E Overexpression in Ovarian Cancer von Eder, Astrid M., Sui, Xiaomei, Rosen, Daniel G., Nolden, Laura K., Cheng, Kwai Wa, Lahad, John P., Kango-Singh, Madhuri, Lu, Karen H., Warneke, Carla L., Atkinson, Edward N., Bedrosian, Isabelle, Keyomarsi, Khandan, Kuo, Wen-lin, Gray, Joe W., Jerry C. P. Yin, Liu, Jinsong, Halder, Georg, Mills, Gordon B., Siminovitch, Louis

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