PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer von Raina, Kanak, Lu, Jing, Qian, Yimin, Altieri, Martha, Gordon, Deborah, Rossi, Ann Marie K., Wang, Jing, Chen, Xin, Dong, Hanqing, Siu, Kam, Winkler, James D., Crew, Andrew P., Crews, Craig M., Coleman, Kevin G.

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Identification and Characterization of Von Hippel-Lindau-Recruiting Proteolysis Targeting Chimeras (PROTACs) of TANK-Binding Kinase 1 von Crew, Andrew P, Raina, Kanak, Dong, Hanqing, Qian, Yimin, Wang, Jing, Vigil, Dominico, Serebrenik, Yevgeniy V, Hamman, Brian D, Morgan, Alicia, Ferraro, Caterina, Siu, Kam, Neklesa, Taavi K, Winkler, James D, Coleman, Kevin G, Crews, Craig M

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PARP inhibitor synthetic lethality in ATM biallelic mutant cancer cell lines is associated with BRCA1/2 and RAD51 downregulation von Muvaffak, Asli, Coleman, Kevin G

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Proteolysis-Targeting Chimeras: Harnessing the Ubiquitin-Proteasome System to Induce Degradation of Specific Target Proteins von Coleman, Kevin G, Crews, Craig M

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Protein targeting chimeric molecules specific for bromodomain and extra-terminal motif family proteins are active against pre-clinical models of multiple myeloma von Zhang, Xiaohui, Lee, Hans C., Shirazi, Fazal, Baladandayuthapani, Veerabhadran, Lin, Heather, Kuiatse, Isere, Wang, Hua, Jones, Richard J., Berkova, Zuzana, Singh, Ram Kumar, Lu, Jing, Qian, Yimin, Raina, Kanak, Coleman, Kevin G., Crews, Craig M., Li, Bingzong, Wang, Huihan, Hailemichael, Yared, Thomas, Sheeba K., Wang, Zhiqiang, Davis, R. Eric, Orlowski, Robert Z.

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Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2 von Peng, Xiao-Ding, Xu, Pei-Zhang, Chen, Mei-Ling, Hahn-Windgassen, Annett, Skeen, Jennifer, Jacobs, Joel, Sundararajan, Deepa, Chen, William S, Crawford, Susan E, Coleman, Kevin G, Hay, Nissim

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Impact of two centuries of intensive agriculture on soil carbon, nitrogen and phosphorus cycling in the UK von Muhammed, Shibu E., Coleman, Kevin, Wu, Lianhai, Bell, Victoria A., Davies, Jessica A.C., Quinton, John N., Carnell, Edward J., Tomlinson, Samuel J., Dore, Anthony J., Dragosits, Ulrike, Naden, Pamela S., Glendining, Margaret J., Tipping, Edward, Whitmore, Andrew P.

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Antitumor Activity and Pharmacology of a Selective Focal Adhesion Kinase Inhibitor, PF-562,271 von ROBERTS, Walter Gregory, UNG, Ethan, COLEMAN, Kevin, LILI YAO, MARTINEZ-ALSINA, Luis, LORENZEN, Marianne, BERLINER, Martin, LUZZIO, Michael, PATEL, Nandini, SCHMITT, Erika, LAGRECA, Susan, JANI, Jitesh, WHALEN, Pamela, WESSEL, Matt, MARR, Eric, GRIFFOR, Matt, VAJDOS, Felix, COOPER, Beth, HULFORD, Catherine, AUTRY, Christofer, RICHTER, Daniel, EMERSON, Earling, JING LIN, KATH, John

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A dataset of CMIP6-based climate scenarios for climate change impact assessment in Great Britain von Semenov, Mikhail A., Senapati, Nimai, Coleman, Kevin, Collins, Adrian L.

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Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta von Garofalo, Robert S, Orena, Stephen J, Rafidi, Kristina, Torchia, Anthony J, Stock, Jeffrey L, Hildebrandt, Audrey L, Coskran, Timothy, Black, Shawn C, Brees, Dominique J, Wicks, Joan R, McNeish, John D, Coleman, Kevin G

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Global climate change and soil carbon stocks; predictions from two contrasting models for the turnover of organic carbon in soil von Jones, C, McConnell, C, Coleman, K, Cox, P, Falloon, P, Jenkinson, D, Powlson, D

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A knockout mutation of a constitutive GPCR in Tetrahymena decreases both G-protein activity and chemoattraction von Lampert, Thomas J, Coleman, Kevin D, Hennessey, Todd M

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Learning Confounds Algometric Assessment of Mechanical Thresholds in Normal Dogs von Coleman, Kevin D., Schmiedt, Chad W., Kirkby, Kristin A., Coleman, Amanda E., Robertson, Sheilah A., Hash, Jon, Lascelles, B. Duncan X.

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How Tillage System Affects the Soil Carbon Dioxide Emission and Wheat Plants Physiological State von Sawinska, Zuzanna, Radzikowska-Kujawska, Dominika, Blecharczyk, Andrzej, Świtek, Stanisław, Piechota, Tomasz, Cieślak, Adam, Cardenas, Laura M., Louro-Lopez, Aranzazu, Gregory, Andrew S., Coleman, Kevin, Lark, R. Murray

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Ready to Fight: Forward Thinking Required for Fort to Port Operations von Coleman, Kevin

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Description of the Anatomy, Surgical Technique, and Outcome of Hemipelvectomy in 4 Dogs and 5 Cats von Barbur, Laura A., Coleman, Kevin D., Schmiedt, Chad W., Radlinsky, MaryAnn G.

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PF-03814735, an orally bioavailable small molecule aurora kinase inhibitor for cancer therapy von Jani, Jitesh P, Arcari, Joel, Bernardo, Vincent, Bhattacharya, Samit K, Briere, David, Cohen, Bruce D, Coleman, Kevin, Christensen, James G, Emerson, Erling O, Jakowski, Amy, Hook, Kenneth, Los, Gerrit, Moyer, James D, Pruimboom-Brees, Ingrid, Pustilnik, Leslie, Rossi, Ann Marie, Steyn, Stefan J, Su, Chunyan, Tsaparikos, Konstantinos, Wishka, Donn, Yoon, Kwansik, Jakubczak, John L

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Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4 von Lu, Jing, Qian, Yimin, Altieri, Martha, Dong, Hanqing, Wang, Jing, Raina, Kanak, Hines, John, Winkler, James D., Crew, Andrew P., Coleman, Kevin, Crews, Craig M.

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Abstract 2379: Elaborating the mechanism of PARP synthetic lethality in ATM loss von Muvaffak, Asli, Coleman, Kevin G.

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Estimating the size of the inert organic matter pool from total soil organic carbon content for use in the Rothamsted carbon model von Falloon, Pete, Smith, Pete, Coleman, Kevin, Marshall, Stewart

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