Validation of the Essential ClpP Protease in Mycobacterium tuberculosis as a Novel Drug Target von Ollinger, Juliane, O'Malley, Theresa, Kesicki, Edward A, Odingo, Joshua, Parish, Tanya

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Synthesis and Evaluation of the 2-Aminothiazoles as Anti-Tubercular Agents von Kesicki, Edward A, Bailey, Mai A, Ovechkina, Yulia, Early, Julie V, Alling, Torey, Bowman, Julie, Zuniga, Edison S, Dalai, Suryakanta, Kumar, Naresh, Masquelin, Thierry, Hipskind, Philip A, Odingo, Joshua O, Parish, Tanya

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A high-throughput screen against pantothenate synthetase (PanC) identifies 3-biphenyl-4-cyanopyrrole-2-carboxylic acids as a new class of inhibitor with activity against Mycobacter... von Kumar, Anuradha, Casey, Allen, Odingo, Joshua, Kesicki, Edward A, Abrahams, Garth, Vieth, Michal, Masquelin, Thierry, Mizrahi, Valerie, Hipskind, Philip A, Sherman, David R, Parish, Tanya

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Epinephrine inhibits PI3Kα via the Hippo kinases von Lin, Ting-Yu, Ramsamooj, Shakti, Perrier, Tiffany, Liberatore, Katarina, Lantier, Louise, Vasan, Neil, Karukurichi, Kannan, Hwang, Seo-Kyoung, Kesicki, Edward A., Kastenhuber, Edward R., Wiederhold, Thorsten, Yaron, Tomer M., Huntsman, Emily M., Zhu, Mengmeng, Ma, Yilun, Paddock, Marcia N., Zhang, Guoan, Hopkins, Benjamin D., McGuinness, Owen, Schwartz, Robert E., Ersoy, Baran A., Cantley, Lewis C., Johnson, Jared L., Goncalves, Marcus D.

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DNA-dependent protein kinase is a molecular target for the development of noncytotoxic radiation-sensitizing drugs von SHINOHARA, Eric T, LING GENG, JIAHUI TAN, HEIDI CHEN, YU SHIR, EDWARDS, Eric, HALBROOK, James, KESICKI, Edward A, KASHISHIAN, Adam, HALLAHAN, Dennis E

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DNA-dependent protein kinase inhibitors as drug candidates for the treatment of cancer von Kashishian, Adam, Douangpanya, Heather, Clark, Darcey, Schlachter, Stephen T, Eary, C Todd, Schiro, Justin G, Huang, Hongmei, Burgess, Larry E, Kesicki, Edward A, Halbrook, James

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Discovery of spirohydantoins as selective, orally bioavailable inhibitors of p300/CBP histone acetyltransferases von Ji, Zhiqin, Clark, Richard F., Bhat, Vikram, Matthew Hansen, T., Lasko, Loren M., Bromberg, Kenneth D., Manaves, Vlasios, Algire, Mikkel, Martin, Ruth, Qiu, Wei, Torrent, Maricel, Jakob, Clarissa G., Liu, Hong, Cole, Philip A., Marmorstein, Ronen, Kesicki, Edward A., Lai, Albert, Michaelides, Michael R.

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Discovery of Spiro Oxazolidinediones as Selective, Orally Bioavailable Inhibitors of p300/CBP Histone Acetyltransferases von Michaelides, Michael R, Kluge, Arthur, Patane, Michael, Van Drie, John H, Wang, Ce, Hansen, T. Matthew, Risi, Roberto M, Mantei, Robert, Hertel, Carmen, Karukurichi, Kannan, Nesterov, Alexandre, McElligott, David, de Vries, Peter, Langston, J. William, Cole, Philip A, Marmorstein, Ronen, Liu, Hong, Lasko, Loren, Bromberg, Kenneth D, Lai, Albert, Kesicki, Edward A

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Phenylboronic Acid−Salicylhydroxamic Acid Bioconjugates. 1. A Novel Boronic Acid Complex for Protein Immobilization von Stolowitz, Mark L, Ahlem, Clarence, Hughes, Karin A, Kaiser, Robert J, Kesicki, Edward A, Li, Guisheng, Lund, Kevin P, Torkelson, Steven M, Wiley, Jean P

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Synthesis and evaluation of the 2,4-diaminoquinazoline series as anti-tubercular agents von Odingo, Joshua, O’Malley, Theresa, Kesicki, Edward A., Alling, Torey, Bailey, Mai Ann, Early, Julie, Ollinger, Juliane, Dalai, Suryakanta, Kumar, Naresh, Singh, Ravindra Vikram, Hipskind, Philip A., Cramer, Jeffrey W., Ioerger, Thomas, Sacchettini, James, Vickers, Richard, Parish, Tanya

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Author Correction: Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours von Lasko, Loren M., Jakob, Clarissa G., Edalji, Rohinton P., Qiu, Wei, Montgomery, Debra, Digiammarino, Enrico L., Hansen, T. Matt, Risi, Roberto M., Frey, Robin, Manaves, Vlasios, Shaw, Bailin, Algire, Mikkel, Hessler, Paul, Lam, Lloyd T., Uziel, Tamar, Faivre, Emily, Ferguson, Debra, Buchanan, Fritz G., Martin, Ruth L., Torrent, Maricel, Chiang, Gary G., Karukurichi, Kannan, Langston, J. William, Weinert, Brian T., Choudhary, Chunaram, de Vries, Peter, Kluge, Arthur F., Patane, Michael A., Van Drie, John H., Wang, Ce, McElligott, David, Kesicki, Edward A., Marmorstein, Ronen, Sun, Chaohong, Cole, Philip A., Rosenberg, Saul H., Michaelides, Michael R., Lai, Albert, Bromberg, Kenneth D.

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Synthesis and Postsynthetic Modification of Oligodeoxynucleotides Containing 4-Thio-2'-deoxyuridine (ds4U) von Coleman, Robert S, Kesicki, Edward A

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Identification of ring-fused pyrazolo pyridin-2-ones as novel poly(ADP-ribose)polymerase-1 inhibitors von Moree, Wilna J., Goldman, Phyllis, Demaggio, Anthony J., Christenson, Erik, Herendeen, Dan, Eksterowicz, John, Kesicki, Edward A., McElligott, David L., Beaton, Graham

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A specific antagonist of the p110δ catalytic component of phosphatidylinositol 3'-kinase, IC486068, enhances radiation-induced tumor vascular destruction von LING GENG, JIAHUAI TAN, HALLAHAN, Dennis E, HIMMELFARB, Eric, SCHUENEMAN, Aaron, NIERMANN, Ken, FU, Allie, CUNEO, Kyle, KESICKI, Edward A, TREIBERG, Jennifer, HAYFLICK, Joel S

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Phenylboronic Acid−Salicylhydroxamic Acid Bioconjugates. 2. Polyvalent Immobilization of Protein Ligands for Affinity Chromatography von Wiley, Jean P, Hughes, Karin A, Kaiser, Robert J, Kesicki, Edward A, Lund, Kevin P, Stolowitz, Mark L

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Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome von Weinert, Brian T., Narita, Takeo, Satpathy, Shankha, Srinivasan, Balaji, Hansen, Bogi K., Schölz, Christian, Hamilton, William B., Zucconi, Beth E., Wang, Wesley W., Liu, Wenshe R., Brickman, Joshua M., Kesicki, Edward A., Lai, Albert, Bromberg, Kenneth D., Cole, Philip A., Choudhary, Chunaram

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Template-Directed Crosslinking of Oligonucleotides: Site-Specific Covalent Modification of dG-N7 within Duplex DNA von Coleman, Robert S, Kesicki, Edward A

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A High-Throughput Screen against Pantothenate Synthetase von Kumar, Anuradha, Casey, Allen, Odingo, Joshua, Kesicki, Edward A, Abrahams, Garth, Vieth, Michal, Masquelin, Thierry, Mizrahi, Valerie, Hipskind, Philip A, Sherman, David R, Parish, Tanya

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Aminopyrimidine derivatives as phosphatidylinositol phosphate kinase inhibitors von Kesicki, Edward A

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Interaction of binuclear transition metal complexes with DNA von Kesicki, Edward A, DeRosch, Mark A, Freeman, Laurie H, Walton, Christine L, Harvey, Daniel F, Trogler, William C

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