Polysorbates 20 and 80 Used in the Formulation of Protein Biotherapeutics: Structure and Degradation Pathways von Kerwin, Bruce A.

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Protect from Light: Photodegradation and Protein Biologics von Kerwin, Bruce A., Remmele, Richard L.

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Specific-Ion Effects on the Aggregation Mechanisms and Protein–Protein Interactions for Anti-streptavidin Immunoglobulin Gamma‑1 von Barnett, Gregory V, Razinkov, Vladimir I, Kerwin, Bruce A, Laue, Thomas M, Woodka, Andrea H, Butler, Paul D, Perevozchikova, Tatiana, Roberts, Christopher J

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Acetate- and Citrate-Specific Ion Effects on Unfolding and Temperature-Dependent Aggregation Rates of Anti-Streptavidin IgG1 von Barnett, Gregory V., Razinkov, Vladimir I., Kerwin, Bruce A., Hillsley, Alexander, Roberts, Christopher J.

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Quantitative Evaluation of Colloidal Stability of Antibody Solutions using PEG-Induced Liquid–Liquid Phase Separation von Wang, Ying, Latypov, Ramil F, Lomakin, Aleksey, Meyer, Julie A, Kerwin, Bruce A, Vunnum, Suresh, Benedek, George B

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Effect of Sugar Molecules on the Viscosity of High Concentration Monoclonal Antibody Solutions von He, Feng, Woods, Christopher E., Litowski, Jennifer R., Roschen, Lauren A., Gadgil, Himanshu S., Razinkov, Vladimir I., Kerwin, Bruce A.

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Shocking Data on Parcel Shipments of Protein Solutions von Siska, Christine, Harber, Paul, Kerwin, Bruce A.

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Roadmap for Drug Product Development and Manufacturing of Biologics von Sampathkumar, Krishnan, Kerwin, Bruce A

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Characterization of Site-Specific Glycation During Process Development of a Human Therapeutic Monoclonal Antibody von Miller, Amanda K., Hambly, David M., Kerwin, Bruce A., Treuheit, Michael J., Gadgil, Himanshu S.

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Development of a Human Antibody Tolerant Mouse Model to Assess the Immunogenicity Risk Due to Aggregated Biotherapeutics von Bi, Vivian, Jawa, Vibha, Joubert, Marisa K., Kaliyaperumal, Arunan, Eakin, Catherine, Richmond, Karen, Pan, Oscar, Sun, Jilin, Hokom, Martha, Goletz, Theresa J., Wypych, Jette, Zhou, Lei, Kerwin, Bruce A., Narhi, Linda O., Arora, Taruna

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Screening of Monoclonal Antibody Formulations Based on High-Throughput Thermostability and Viscosity Measurements: Design of Experiment and Statistical Analysis von He, Feng, Woods, Christopher E., Trilisky, Egor, Bower, Keith M., Litowski, Jennifer R., Kerwin, Bruce A., Becker, Gerald W., Narhi, Linda O., Razinkov, Vladimir I.

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Biochemical Assessment of Erythropoietin Products From Asia Versus US Epoetin alfa Manufactured by Amgen von Park, Sungae S., Park, Jihea, Ko, Jason, Chen, Louise, Meriage, David, Crouse-Zeineddini, Jill, Wong, Wendy, Kerwin, Bruce A.

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Linking the Solution Viscosity of an IgG2 Monoclonal Antibody to Its Structure as a Function of pH and Temperature von Cheng, Weiqiang, Joshi, Sangeeta B., Jain, Nishant Kumar, He, Feng, Kerwin, Bruce A., Volkin, David B., Russell Middaugh, C.

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The Development of a Novel Aflibercept Formulation for Ocular Delivery von Floyd, J Alaina, Gillespie, Alison J, Nightlinger, Nancy S, Siska, Christine, Kerwin, Bruce A

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Highly Aggregated Antibody Therapeutics Can Enhance the in Vitro Innate and Late-stage T-cell Immune Responses von Joubert, Marisa K., Hokom, Martha, Eakin, Catherine, Zhou, Lei, Deshpande, Meghana, Baker, Matthew P., Goletz, Theresa J., Kerwin, Bruce A., Chirmule, Naren, Narhi, Linda O., Jawa, Vibha

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Entanglement Model of Antibody Viscosity von Schmit, Jeremy D, He, Feng, Mishra, Shradha, Ketchem, Randal R, Woods, Christopher E, Kerwin, Bruce A

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Osmolyte Effects on Monoclonal Antibody Stability and Concentration-Dependent Protein Interactions with Water and Common Osmolytes von Barnett, Gregory V, Razinkov, Vladimir I, Kerwin, Bruce A, Blake, Steven, Qi, Wei, Curtis, Robin A, Roberts, Christopher J

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Adapting the chemical unfolding assay for high-throughput protein screening using experimental and spectroscopic corrections von Floyd, J. Alaina, Siska, Christine, Clark, Rutilio H., Kerwin, Bruce A., Shaver, Jeremy M.

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Reversible Hydrogen Transfer Reactions of Cysteine Thiyl Radicals in Peptides: the Conversion of Cysteine into Dehydroalanine and Alanine, and of Alanine into Dehydroalanine von Mozziconacci, Olivier, Kerwin, Bruce A, Schöneich, Christian

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The Photolysis of Disulfide Bonds in IgG1 and IgG2 Leads to Selective Intramolecular Hydrogen Transfer Reactions of Cysteine Thiyl Radicals, Probed by Covalent H/D Exchange and RPL... von Zhou, Shuxia, Mozziconacci, Olivier, Kerwin, Bruce A., Schöneich, Christian

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