The molecular details of cytokine signaling via the JAK/STAT pathway von Morris, Rhiannon, Kershaw, Nadia J., Babon, Jeffrey J.

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The molecular basis of JAK/STAT inhibition by SOCS1 von Liau, Nicholas P. D., Laktyushin, Artem, Lucet, Isabelle S., Murphy, James M., Yao, Shenggen, Whitlock, Eden, Callaghan, Kimberley, Nicola, Nicos A., Kershaw, Nadia J., Babon, Jeffrey J.

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Suppression of Cytokine Signaling by SOCS3: Characterization of the Mode of Inhibition and the Basis of Its Specificity von Babon, Jeffrey J., Kershaw, Nadia J., Murphy, James M., Varghese, Leila N., Laktyushin, Artem, Young, Samuel N., Lucet, Isabelle S., Norton, Raymond S., Nicola, Nicos A.

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A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity von Liang, Shuwei, Tran, Eric, Du, Xin, Dong, Jiajun, Sudholz, Harrison, Chen, Hao, Qu, Zihan, Huntington, Nicholas D., Babon, Jeffrey J., Kershaw, Nadia J., Zhang, Zhong-Yin, Baell, Jonathan B., Wiede, Florian, Tiganis, Tony

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SOCS3 binds specific receptor–JAK complexes to control cytokine signaling by direct kinase inhibition von Kershaw, Nadia J, Murphy, James M, Liau, Nicholas P D, Varghese, Leila N, Laktyushin, Artem, Whitlock, Eden L, Lucet, Isabelle S, Nicola, Nicos A, Babon, Jeffrey J

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Aspartate/asparagine-β-hydroxylase crystal structures reveal an unexpected epidermal growth factor-like domain substrate disulfide pattern von Pfeffer, Inga, Brewitz, Lennart, Krojer, Tobias, Jensen, Sacha A., Kochan, Grazyna T., Kershaw, Nadia J., Hewitson, Kirsty S., McNeill, Luke A., Kramer, Holger, Münzel, Martin, Hopkinson, Richard J., Oppermann, Udo, Handford, Penny A., McDonough, Michael A., Schofield, Christopher J.

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Structural and functional analysis of target recognition by the lymphocyte adaptor protein LNK von Morris, Rhiannon, Zhang, Yaoyuan, Ellyard, Julia I., Vinuesa, Carola G., Murphy, James M., Laktyushin, Artem, Kershaw, Nadia J., Babon, Jeffrey J.

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The Role of LNK (SH2B3) in the Regulation of JAK-STAT Signalling in Haematopoiesis von Morris, Rhiannon, Butler, Liesl, Perkins, Andrew, Kershaw, Nadia J, Babon, Jeffrey J

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Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands von Linossi, Edmond M., Li, Kunlun, Veggiani, Gianluca, Tan, Cyrus, Dehkhoda, Farhad, Hockings, Colin, Calleja, Dale J., Keating, Narelle, Feltham, Rebecca, Brooks, Andrew J., Li, Shawn S., Sidhu, Sachdev S., Babon, Jeffrey J., Kershaw, Nadia J., Nicholson, Sandra E.

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Cryo-EM structure of the extracellular domain of murine Thrombopoietin Receptor in complex with Thrombopoietin von Sarson-Lawrence, Kaiseal T. G., Hardy, Joshua M., Iaria, Josephine, Stockwell, Dina, Behrens, Kira, Saiyed, Tamanna, Tan, Cyrus, Jebeli, Leila, Scott, Nichollas E., Dite, Toby A., Nicola, Nicos A., Leis, Andrew P., Babon, Jeffrey J., Kershaw, Nadia J.

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Author Correction: Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands von Linossi, Edmond M., Li, Kunlun, Veggiani, Gianluca, Tan, Cyrus, Dehkhoda, Farhad, Hockings, Colin, Calleja, Dale J., Keating, Narelle, Feltham, Rebecca, Brooks, Andrew J., Li, Shawn S., Sidhu, Sachdev S., Babon, Jeffrey J., Kershaw, Nadia J., Nicholson, Sandra E.

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Notch ligand delta-like1: X-ray crystal structure and binding affinity von Kershaw, Nadia J, Church, Nicole L, Griffin, Michael D W, Luo, Cindy S, Adams, Timothy E, Burgess, Antony W

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Roquin binds microRNA-146a and Argonaute2 to regulate microRNA homeostasis von Srivastava, Monika, Duan, Guowen, Kershaw, Nadia J., Athanasopoulos, Vicki, Yeo, Janet H. C., Ose, Toyoyuki, Hu, Desheng, Brown, Simon H. J., Jergic, Slobodan, Patel, Hardip R., Pratama, Alvin, Richards, Sashika, Verma, Anil, Jones, E. Yvonne, Heissmeyer, Vigo, Preiss, Thomas, Dixon, Nicholas E., Chong, Mark M. W., Babon, Jeffrey J., Vinuesa, Carola G.

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Crystal structure of the TRIM25 B30.2 (PRYSPRY) domain: a key component of antiviral signalling von D'Cruz, Akshay A, Kershaw, Nadia J, Chiang, Jessica J, Wang, May K, Nicola, Nicos A, Babon, Jeffrey J, Gack, Michaela U, Nicholson, Sandra E

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SOCS2 regulation of growth hormone signaling requires a canonical interaction with phosphotyrosine von Li, Kunlun, Meza Guzman, Lizeth G, Whitehead, Lachlan, Leong, Evelyn, Kueh, Andrew, Alexander, Warren S, Kershaw, Nadia J, Babon, Jeffrey J, Doggett, Karen, Nicholson, Sandra E

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Context-restricted PD-(L)1 checkpoint agonism by CTLA4-Ig therapies inhibits T cell activity von Oxley, Ethan P., Kershaw, Nadia J., Louis, Cynthia, Goodall, Katharine J., Garwood, Maximilian M., Jee Ho, Skye Min, Voo, Veronica T.F., Park, Hae-Young, Iaria, Josephine, Wong, Lilian L.L., Lebenbaum, Ariel G., Wiranata, Stephanie, Pang, Ee Shan, Edwards, Emily S.J., D’Silva, Damian B., Hansen, Jacinta, van Zelm, Menno C., O’Keeffe, Meredith, Hogarth, P. Mark, Haynes, Nicole M., Huntington, Nicholas D., Wicks, Ian P., Dickins, Ross A.

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VHL: Cullin-g the Hypoxic Response von Kershaw, Nadia J., Babon, Jeffrey J.

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Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation von Scotti, John S., Leung, Ivanhoe K. H., Ge, Wei, Bentley, Michael A., Paps, Jordi, Kramer, Holger B., Lee, Joongoo, Aik, WeiShen, Choi, Hwanho, Paulsen, Steinar M., Bowman, Lesley A. H., Loik, Nikita D., Horita, Shoichiro, Ho, Chia-hua, Kershaw, Nadia J., Tang, Christoph M., Claridge, Timothy D. W., Preston, Gail M., McDonough, Michael A., Schofield, Christopher J.

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JAK1 Takes a FERM Hold of Type II Cytokine Receptors von Babon, Jeffrey J., Liau, Nicholas P.D., Kershaw, Nadia J.

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Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation von Ramiscal, Roybel R, Parish, Ian A, Lee-Young, Robert S, Babon, Jeffrey J, Blagih, Julianna, Pratama, Alvin, Martin, Jaime, Hawley, Naomi, Cappello, Jean Y, Nieto, Pablo F, Ellyard, Julia I, Kershaw, Nadia J, Sweet, Rebecca A, Goodnow, Christopher C, Jones, Russell G, Febbraio, Mark A, Vinuesa, Carola G, Athanasopoulos, Vicki

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