SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration von Figley, Matthew D., Gu, Weixi, Nanson, Jeffrey D., Shi, Yun, Sasaki, Yo, Cunnea, Katie, Malde, Alpeshkumar K., Jia, Xinying, Luo, Zhenyao, Saikot, Forhad K., Mosaiab, Tamim, Masic, Veronika, Holt, Stephanie, Hartley-Tassell, Lauren, McGuinness, Helen Y., Manik, Mohammad K., Bosanac, Todd, Landsberg, Michael J., Kerry, Philip S., Mobli, Mehdi, Hughes, Robert O., Milbrandt, Jeffrey, Kobe, Bostjan, DiAntonio, Aaron, Ve, Thomas

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Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules von Shi, Yun, Kerry, Philip S., Nanson, Jeffrey D., Bosanac, Todd, Sasaki, Yo, Krauss, Raul, Saikot, Forhad K., Adams, Sarah E., Mosaiab, Tamim, Masic, Veronika, Mao, Xianrong, Rose, Faith, Vasquez, Eduardo, Furrer, Marieke, Cunnea, Katie, Brearley, Andrew, Gu, Weixi, Luo, Zhenyao, Brillault, Lou, Landsberg, Michael J., DiAntonio, Aaron, Kobe, Bostjan, Milbrandt, Jeffrey, Hughes, Robert O., Ve, Thomas

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Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion von Russell, Rupert J, Kerry, Philip S, Stevens, David J, Steinhauer, David A, Martin, Stephen R, Gamblin, Steven J, Skehel, John J

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Serendipitous Discovery of a Potent Influenza Virus A Neuraminidase Inhibitor von Mohan, Sankar, Kerry, Philip S., Bance, Nicole, Niikura, Masahiro, Pinto, B. Mario

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Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein von Hale, Benjamin G, Kerry, Philip S, Jackson, David, Precious, Bernard L, Gray, Alexander, Killip, Marian J, Randall, Richard E, Russell, Rupert J

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PROTACs Targeting BRM (SMARCA2) Afford Selective In Vivo Degradation over BRG1 (SMARCA4) and Are Active in BRG1 Mutant Xenograft Tumor Models von Berlin, Michael, Cantley, Jennifer, Bookbinder, Mark, Bortolon, Elizabeth, Broccatelli, Fabio, Cadelina, Greg, Chan, Emily W., Chen, Huifen, Chen, Xin, Cheng, Yunxing, Cheung, Tommy K., Davenport, Kim, DiNicola, Dean, Gordon, Debbie, Hamman, Brian D., Harbin, Alicia, Haskell, Roy, He, Mingtao, Hole, Alison J., Januario, Thomas, Kerry, Philip S., Koenig, Stefan G., Li, Limei, Merchant, Mark, Pérez-Dorado, Inmaculada, Pizzano, Jennifer, Quinn, Connor, Rose, Christopher M., Rousseau, Emma, Soto, Leofal, Staben, Leanna R., Sun, Hongming, Tian, Qingping, Wang, Jing, Wang, Weifeng, Ye, Crystal S., Ye, Xiaofen, Zhang, Penghong, Zhou, Yuhui, Yauch, Robert, Dragovich, Peter S.

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A transient homotypic interaction model for the influenza A virus NS1 protein effector domain von Kerry, Philip S, Ayllon, Juan, Taylor, Margaret A, Hass, Claudia, Lewis, Andrew, García-Sastre, Adolfo, Randall, Richard E, Hale, Benjamin G, Russell, Rupert J

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Novel Bat Influenza Virus NS1 Proteins Bind Double-Stranded RNA and Antagonize Host Innate Immunity von Turkington, Hannah L, Juozapaitis, Mindaugas, Kerry, Philip S, Aydillo, Teresa, Ayllon, Juan, García-Sastre, Adolfo, Schwemmle, Martin, Hale, Benjamin G

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Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase von von Itzstein, Mark, Rudrawar, Santosh, Dyason, Jeffrey C, Rameix-Welti, Marie-Anne, Rose, Faith J, Kerry, Philip S, Russell, Rupert J. M, van der Werf, Sylvie, Thomson, Robin J, Naffakh, Nadia

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Structural basis for a class of nanomolar influenza A neuraminidase inhibitors von Kerry, Philip S., Mohan, Sankar, Russell, Rupert J. M., Bance, Nicole, Niikura, Masahiro, Pinto, B. Mario

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Analysis of Influenza A Virus NS1 Dimer Interfaces in Solution by Pulse EPR Distance Measurements von Kerry, Philip S, Turkington, Hannah L, Ackermann, Katrin, Jameison, Stephen A, Bode, Bela E

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Synthesis, structure and inhibitory activity of a stereoisomer of oseltamivir carboxylate von Sartori, Andrea, Dell'Amico, Luca, Battistini, Lucia, Curti, Claudio, Rivara, Silvia, Pala, Daniele, Kerry, Philip S, Pelosi, Giorgio, Casiraghi, Giovanni, Rassu, Gloria, Zanardi, Franca

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Synthesis and evaluation of novel 3-C-alkylated-Neu5Ac2en derivatives as probes of influenza virus sialidase 150-loop flexibility von Rudrawar, Santosh, Kerry, Philip S, Rameix-Welti, Marie-Anne, Maggioni, Andrea, Dyason, Jeffrey C, Rose, Faith J, van der Werf, Sylvie, Thomson, Robin J, Naffakh, Nadia, Russell, Rupert J M, von Itzstein, Mark

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A cluster of conserved basic amino acids near the C-terminus of the PB1 subunit of the influenza virus RNA polymerase is involved in the regulation of viral transcription von Kerry, Philip S, Willsher, Nicholas, Fodor, Ervin

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Exploring the Interactions of Unsaturated Glucuronides with Influenza Virus Sialidase von Bhatt, Beenu, Böhm, Raphael, Kerry, Philip S, Dyason, Jeffrey C, Russell, Rupert J. M, Thomson, Robin J, von Itzstein, Mark

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Uncovering the molecular basis for SARM1 activation von Kerry, Philip S., Brearley, Andrew, Furrer, Marieke, Cunnea, Katie

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The specific monocarboxylate transporter-1 (MCT-1) inhibitor, AR-C117977, induces donor-specific suppression, reducing acute and chronic allograft rejection in the rat von EKBERG, Henrik, ZHONGQUAN QI, KERRY, Philip J, WILSON, Elaine, DONALD, David K, PAHLMAN, Clara, VERESS, Bela, BUNDICK, Robert V, CRAGGS, Robert I, HOLNESS, Elain, EDWARDS, Susan, MURRAY, Clare M, FERGUSON, Douglas

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Development of a Selective Inhibitor of Protein Arginine Deiminase 2 von Muth, Aaron, Subramanian, Venkataraman, Beaumont, Edward, Nagar, Mitesh, Kerry, Philip, McEwan, Paul, Srinath, Hema, Clancy, Kathleen, Parelkar, Sangram, Thompson, Paul R

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Serendipitous Discovery of a Potent Influenza Virus A Neuraminidase Inhibitor von Mohan, Sankar, Kerry, Philip S., Bance, Nicole, Niikura, Masahiro, Pinto, B. Mario

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Conservation of a crystallographic interface suggests a role for β-sheet augmentation in influenza virus NS1 multifunctionality von Kerry, Philip S., Long, Elizabeth, Taylor, Margaret A., Russell, Rupert J. M.

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