Structure, function and evolution of multidomain proteins von Vogel, Christine, Bashton, Matthew, Kerrison, Nicola D, Chothia, Cyrus, Teichmann, Sarah A

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The link between family history and risk of type 2 diabetes is not explained by anthropometric, lifestyle or genetic risk factors: the EPIC-InterAct study von Scott, R A, Langenberg, C, Sharp, S J, Franks, P W, Rolandsson, O, Drogan, D, van der Schouw, Y T, Ekelund, U, Kerrison, N D, Ardanaz, E, Arriola, L, Balkau, B, Barricarte, A, Barroso, I, Bendinelli, B, Beulens, J W J, Boeing, H, de Lauzon-Guillain, B, Deloukas, P, Fagherazzi, G, Gonzalez, C, Griffin, S J, Groop, L C, Halkjaer, J, Huerta, J M, Kaaks, R, Khaw, K T, Krogh, V, Nilsson, P M, Norat, T, Overvad, K, Panico, S, Rodriguez-Suarez, L, Romaguera, D, Romieu, I, Sacerdote, C, Sánchez, M J, Spijkerman, A M W, Teucher, B, Tjonneland, A, Tumino, R, van der A, D L, Wark, P A, McCarthy, M I, Riboli, E, Wareham, N J

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Coordinated multitissue transcriptional and plasma metabonomic profiles following acute caloric restriction in mice von Selman, Colin, Kerrison, Nicola D, Cooray, Anisha, Piper, Matthew D. W, Lingard, Steven J, Barton, Richard H, Schuster, Eugene F, Blanc, Eric, Gems, David, Nicholson, Jeremy K, Thornton, Janet M, Partridge, Linda, Withers, Dominic J

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Circulating Fetuin-A and risk of Type 2 Diabetes: a Mendelian randomization analysis von Kröger, J, Meidtner, K, Stefan, N, Guevara, M, Kerrison, ND, Ardanaz, E, Aune, D, Boeing, H, Dorronsoro, M, Dow, C, Fagherazzi, G, Franks, PW, Freisling, H, Gunter, MJ, Huerta, JM, Kaaks, R, Key, TJ, Khaw, KT, Krogh, V, Kühn, T, Mancini, FR, Mattiello, A, Nilsson, PM, Olsen, A, Overvad, K, Palli, D, Quirós, JR, Rolandsson, O, Sacerdote, C, Sala, N, Salamanca-Fernández, E, Sluijs, I, Spijkerman, AM, Tjonneland, A, Tsilidis, KK, Tumino, R, Van der Schouw, YT, Forouhi, NG, Sharp, SJ, Langenberg, C, Riboli, E, Schulze, MB, Wareham, NJ

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Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance von Lotta, LA, Gulati, P, Day, FR, Payne, F, Ongen, H, Van De Bunt, M, Gaulton, KJ, Eicher, JD, Sharp, SJ, Luan, J, De Lucia Rolfe, E, Stewart, ID, Wheeler, E, Willems, SM, Adams, C, Yaghootkar, H, Forouhi, NG, Kerrison, ND, Sims, M, Lucarelli, DME, Deloukas, P, McCarthy, MI, Arriola, L, Balkau, B, Barricarte, A, Boeing, H, Franks, PW, Gonzalez, C, Grioni, S, Kaaks, R, Key, TJ, Navarro, C, Nilsson, PM, Overvad, K, Palli, D, Panico, S, Quirós, JR, Rolandsson, O, Sacerdote, C, Salamanca-Fernández, E, Slimani, N, Tjonneland, A, Tumino, R, Spijkerman, AMW, Van Der A, DL, Van Der Schouw, YT, Riboli, E, Semple, RK, Stears, A, George, S, Walker, M, Gurnell, E, Maguire, D, Mukhtar, R, Nag, S, Adler, A, Soeters, MR, Laji, K, Watt, A, Aylwin, S, Johnson, A, Rayman, G, Hanna, F, Ellard, S, Ross, R, Blaslov, K, Duvnjak, LS, Khaw, KT, Johnson, AD, Frayling, T, Perry, JRB, Dermitzakis, E, Barroso, I, Wareham, NJ, Savage, DB, Langenberg, C, O'Rahilly, S, Scott, RA

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Rare coding variants and X-linked loci associated with age at menarche von Lunetta, KL, Day, FR, Sulem, P, Ruth, KS, Tung, JY, Hinds, DA, Esko, T, He, C, Huffman, JE, Mihailov, E, Robino, A, Rose, LM, Schick, UM, Stolk, L, Teumer, A, Traglia, M, Wang, CA, Yerges-Armstrong, LM, Antoniou, AC, Barbieri, C, Coviello, AD, Cucca, F, Demerath, EW, Dunning, AM, Gandin, I, Grove, ML, Gudbjartsson, DF, Hocking, LJ, Hofman, A, Huang, J, Jackson, RD, Karasik, D, Kriebel, J, Lange, EM, Lange, LA, Langenberg, C, Li, X, Luan, J, Maegi, R, Morrison, AC, Padmanabhan, S, Polasek, O, Porteous, D, Reiner, AP, Rivadeneira, F, Rudan, I, Sala, CF, Scott, RA, Voelker, U, Vozzi, D, Zygmunt, M, Boerwinkle, E, Buring, JE, Crisponi, L, Easton, DF, Hayward, C, Hu, FB, Liu, S, Metspalu, A, Pennell, CE, Ridker, PM, Streeten, EA, Toniolo, D, Uitterlinden, AG, Ulivi, S, Voelzke, H, Wareham, NJ, Wellons, M, Thorsteinsdottir, U, Murray, A, Stefansson, K, Perry, JRB, Forouhi, NG, Kerrison, ND, Sims, M, Barroso, I, Deloukas, P, McCarthy, MI, Arriola, L, Barricarte, A, Franks, PW, Gonzalez, C, Grioni, S, Key, TJ, Palli, D, Panico, S, Ramon Quiros, J, Rolandsson, O, Sacerdote, C, Sanchez, M-J, Slimani, N, Tjonneland, A, Tumino, R, van der A, DL, van der Schouw, YT, Riboli, E, Smith, BH, Campbell, A, Deary, IJ, McIntosh, AM

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Gene-Lifestyle Interaction and Type 2 Diabetes: The EPIC InterAct Case-Cohort Study von Langenberg, C, Sharp, SJ, Franks, PW, Scott, RA, Deloukas, P, Forouhi, NG, Froguel, P, Groop, LC, Hansen, T, Palla, L, Pedersen, O, Schulze, MB, Tormo, M-J, Wheeler, E, Agnoli, C, Arriola, L, Barricarte, A, Boeing, H, Clarke, GM, Clavel-Chapelon, F, Duell, EJ, Fagherazzi, G, Kaaks, R, Kerrison, ND, Key, TJ, Khaw, KT, Kroeger, J, Lajous, M, Morris, AP, Navarro, C, Nilsson, PM, Overvad, K, Palli, D, Panico, S, Quiros, JR, Rolandsson, O, Sacerdote, C, Sanchez, M-J, Slimani, N, Spijkerman, AMW, Tumino, R, van der A, DL, van der Schouw, YT, Barroso, I, McCarthy, MI, Riboli, E, Wareham, NJ

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Long-Term Risk of Incident Type 2 Diabetes and Measures of Overall and Regional Obesity: The EPIC-InterAct Case-Cohort Study von Langenberg, C, Sharp, SJ, Schulze, MB, Rolandsson, O, Overvad, K, Forouhi, NG, Spranger, J, Drogan, D, Maria Huerta, J, Arriola, L, de Lauzon-Guillan, B, Tormo, M-J, Ardanaz, E, Balkau, B, Beulens, JWJ, Boeing, H, Bueno-de-Mesquita, HB, Clavel-Chapelon, F, Crowe, FL, Franks, PW, Gonzalez, CA, Grioni, S, Halkjaer, J, Hallmans, G, Kaaks, R, Kerrison, ND, Key, TJ, Khaw, KT, Mattiello, A, Nilsson, P, Norat, T, Palla, L, Palli, D, Panico, S, Ramon Quiros, J, Romaguera, D, Romieu, I, Sacerdote, C, Sanchez, M-J, Slimani, N, Sluijs, I, Spijkerman, AMW, Teucher, B, Tjonneland, A, Tumino, R, Daphne, LVDA, van der Schouw, YT, Feskens, EJM, Riboli, E, Wareham, NJ

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Synergistic insights into human health from aptamer- and antibody-based proteomic profiling von Pietzner, M, Wheeler, E, Carrasco-Zanini, J, Kerrison, ND, Oerton, E, Koprulu, M, Luan, J, Hingorani, AD, Williams, SA, Wareham, NJ, Langenberg, C

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Mapping the proteo-genomic convergence of human diseases von Pietzner, M, Wheeler, E, Carrasco-Zanini, J, Cortes, A, Koprulu, M, Woerheide, MA, Oerton, E, Cook, J, Stewart, ID, Kerrison, ND, Luan, J, Raffler, J, Arnold, M, Arlt, W, O'Rahilly, S, Kastenmueller, G, Gamazon, ER, Hingorani, AD, Scott, RA, Wareham, NJ, Langenberg, C

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Genetic architecture of host proteins involved in SARS-CoV-2 infection von Pietzner, Maik, Wheeler, E, Carrasco-Zanini, J, Raffler, J, Kerrison, ND, Oerton, E, Au Yeung, V, Luan, J, Finan, C, Casas, JP, Ostroff, R, Williams, SA, Kastenmüller, G, Ralser, M, Gamazon, ER, Wareham, NJ, Hingorani, AD, Langenberg, C

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Genetic architecture of host proteins involved in SARS-CoV-2 infection von Pietzner, M, Wheeler, E, Carrasco-Zanini, J, Raffler, J, Kerrison, ND, Oerton, E, Auyeung, VPW, Luan, J, Finan, C, Casas, JP, Ostroff, R, Williams, SA, Kastenmüller, G, Ralser, M, Gamazon, ER, Wareham, NJ, Hingorani, AD, Langenberg, C

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Long-term risk of incident type 2 diabetes and measures of overall and regional obesity: the EPIC-InterAct case-cohort study von InterAct Consortium, Langenberg, C, Sharp, SJ, Schulze, MB, Rolandsson, O, Overvad, K, Forouhi, NG, Spranger, J, Drogan, D, Huerta, JM, Arriola, L, de Lauzon-Guillan, B, Tormo, MJ, Ardanaz, E, Balkau, B, Beulens, JW, Boeing, H, Bueno-de-Mesquita, HB, Clavel-Chapelon, F, Crowe, FL, Franks, PW, Gonzalez, CA, Grioni, S, Halkjaer, J, Hallmans, G, Kaaks, R, Kerrison, ND, Key, TJ, Khaw, KT, Mattiello, A, Nilsson, P, Norat, T, Palla, L, Palli, D, Panico, S, Quirós, JR, Romaguera, D, Romieu, I, Sacerdote, C, Sánchez, MJ, Slimani, N, Sluijs, I, Spijkerman, AM, Teucher, B, Tjonneland, A, Tumino, R, van der A, DL, van der Schouw, YT, Feskens, EJ, Riboli, E, Wareham, NJ

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A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity von Zhou, Sirui, Butler-Laporte, Guillaume, Nakanishi, Tomoko, Morrison, David R., Afilalo, Jonathan, Afilalo, Marc, Laurent, Laetitia, Pietzner, Maik, Kerrison, Nicola, Zhao, Kaiqiong, Brunet-Ratnasingham, Elsa, Henry, Danielle, Kimchi, Nofar, Afrasiabi, Zaman, Rezk, Nardin, Bouab, Meriem, Petitjean, Louis, Guzman, Charlotte, Xue, Xiaoqing, Tselios, Chris, Vulesevic, Branka, Adeleye, Olumide, Abdullah, Tala, Almamlouk, Noor, Chen, Yiheng, Chassé, Michaël, Durand, Madeleine, Paterson, Clare, Normark, Johan, Frithiof, Robert, Lipcsey, Miklós, Hultström, Michael, Greenwood, Celia M. T., Zeberg, Hugo, Langenberg, Claudia, Thysell, Elin, Pollak, Michael, Mooser, Vincent, Forgetta, Vincenzo, Kaufmann, Daniel E., Richards, J. Brent

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SARS-CoV-2 infection rates of antibody-positive compared with antibody-negative health-care workers in England: a large, multicentre, prospective cohort study (SIREN) von Wellington, Edgar, Cole, Michelle J, Brown, Colin S, Hopkins, Susan, Aziz, H, Camero, D, Chand, MA, Charlett, A, Crawford, H, Cole, M, Foulkes, S, Harrington, P, Hewson, J, Islam, J, Kirwan, P, Lopez-Bernal, J, Mabey, L, McGregor, R, Miah, S, Oguti, B, Organ, S, Patel, M, Platt, S, Ramsay, M, Robotham, J, Rowe, C, Shrotri, M, Simmons, R, Staves, P, Tengbe, A, Wallace, S, Wellington, E, Zambon, M, Campbell, S, Stewart, S, Mcwilliam, S, Winchester, S, Watt, A, Slawson, N, Boyd, G, Matthews, R, Whileman, A, Jones, C, Horne, S, Walker, N, Agwuh, K, Maxwell, V, O'Kelly, A, Ridley, P, Cowley, A, Swift, P, Democratis, J, Meda, M, Smith, H, Swan, A, Murira, J, Gantert, K, Chawla, A, Westell, F, Williams, M, Crosby-Nwaobi, R, McKerron, G, Templeton, K, Elumogo, N, Elliott, J, Padgett, D, Mirfenderesky, M, Cross, A, Howard, M, Brand, S, Sheridan, L, Wadams, B, Mouland, J, Giles, J, Boldock, E, Gormley, S, Tazzyman, S, Jones, A, Price, C, Pepperell, J, Schultz, M, McCracken, D, Kalakonda, N, Khanduri, S, Harwood, J, Payne, B, Staines, N, Hughes, LE, Roebuck, A, Reynolds, T, Wiselka, M, Virgilio, E, Chin, T, Jones, N, Mills, G, Todd, N, Jeffery, K, Dunachie, S, De Silva, T, Heeney, JL

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Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length von Li, Chen, Stoma, Svetlana, Lotta, Luca A., Warner, Sophie, Albrecht, Eva, Allione, Alessandra, Arp, Pascal P., Broer, Linda, Buxton, Jessica L., Da Silva Couto Alves, Alexessander, Deelen, Joris, Fedko, Iryna O., Gordon, Scott D., Jiang, Tao, Karlsson, Robert, Kerrison, Nicola, Loe, Taylor K., Mangino, Massimo, Milaneschi, Yuri, Miraglio, Benjamin, Pervjakova, Natalia, Russo, Alessia, Surakka, Ida, van der Spek, Ashley, Verhoeven, Josine E., Amin, Najaf, Beekman, Marian, Blakemore, Alexandra I., Canzian, Federico, Hamby, Stephen E., Hottenga, Jouke-Jan, Jones, Peter D., Jousilahti, Pekka, Mägi, Reedik, Medland, Sarah E., Montgomery, Grant W., Nyholt, Dale R., Perola, Markus, Pietiläinen, Kirsi H., Salomaa, Veikko, Sillanpää, Elina, Suchiman, H. Eka, van Heemst, Diana, Willemsen, Gonneke, Agudo, Antonio, Boeing, Heiner, Boomsma, Dorret I., Chirlaque, Maria-Dolores, Fagherazzi, Guy, Ferrari, Pietro, Franks, Paul, Gieger, Christian, Eriksson, Johan Gunnar, Gunter, Marc, Hägg, Sara, Hovatta, Iiris, Imaz, Liher, Kaprio, Jaakko, Kaaks, Rudolf, Key, Timothy, Krogh, Vittorio, Martin, Nicholas G., Melander, Olle, Metspalu, Andres, Moreno, Concha, Onland-Moret, N. Charlotte, Nilsson, Peter, Ong, Ken K., Overvad, Kim, Palli, Domenico, Panico, Salvatore, Pedersen, Nancy L., Penninx, Brenda W.J. H., Quirós, J. Ramón, Jarvelin, Marjo Riitta, Rodríguez-Barranco, Miguel, Scott, Robert A., Severi, Gianluca, Slagboom, P. Eline, Spector, Tim D., Tjonneland, Anne, Trichopoulou, Antonia, Tumino, Rosario, Uitterlinden, André G., van der Schouw, Yvonne T., van Duijn, Cornelia M., Weiderpass, Elisabete, Denchi, Eros Lazzerini, Matullo, Giuseppe, Butterworth, Adam S., Danesh, John, Samani, Nilesh J., Wareham, Nicholas J., Nelson, Christopher P., Langenberg, Claudia, Codd, Veryan

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Modelling potential production of macroalgae farms in UK and Dutch coastal waters von van der Molen, Johan, Ruardij, Piet, Mooney, Karen, Kerrison, Philip, O'Connor, Nessa E, Gorman, Emma, Timmermans, Klaas, Wright, Serena, Kelly, Maeve, Hughes, Adam D, Capuzzo, Elisa

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Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci von Reschen, Michael E, Mahajan, Anubha, William Rayner, N, Scott, Laura J, Yengo, Loic, Wahl, Simone, Kestler, Hans, Chheda, Himanshu, Eisele, Lewin, Steinthorsdottir, Valgerdur, Chen, Han, Fuchsberger, Christian, Kwan, Phoenix, Thomsen, Soren K, Rundle, Jana K, van de Bunt, Martijn, Voight, Benjamin F, Abecasis, Gonçalo R, Baldassarre, Damiano, Carey, Jason, Chines, Peter S, Crenshaw, Andrew T, Edkins, Sarah, Eury, Elodie, Fontanillas, Pierre, Franks, Paul W, Gertow, Karl, Groves, Christopher J, Hassinen, Maija, Herder, Christian, Hreidarsson, Astradur B, Jackson, Anne U, Jonsson, Anna, Jørgensen, Marit E, Jørgensen, Torben, Kao, Wen-Hong L, Kerrison, Nicola D, Kinnunen, Leena, Kravic, Jasmina, Langford, Cordelia, Lichtner, Peter, Lindholm, Eero, Lobbens, Stéphane, Luan, Jian'an, Meyer, Julia, Mihailov, Evelin, Mühleisen, Thomas W, Navarro, Carmen, Oskolkov, Nikolay N, Pechlivanis, Sonali, Platou, Carl G P, Rybin, Denis, van der Schouw, Yvonne T, Sennblad, Bengt, Steinbach, Gerald, Storm, Petter, Sun, Qi, Thorand, Barbara, Tikkanen, Emmi, Trakalo, Joseph, Tremoli, Elena, Wood, Andrew R, Zeggini, Eleftheria, Birney, Ewan, Pasquali, Lorenzo, Pankow, James S, van Duijn, Cornelia, Sijbrands, Eric, Hu, Frank B, Thorsteinsdottir, Unnur, Stefansson, Kari, Lakka, Timo A, Rauramaa, Rainer, Stumvoll, Michael, Korpi-Hyövälti, Eeva, Kuusisto, Johanna, Metspalu, Andres, Jöcke, Karl-Heinz, Moebus, Susanne, Bergman, Richard N, Collins, Francis S, Mohlke, Karen L, Koistinen, Heikki, Tuomilehto, Jaakko, Deloukas, Panagiotis, Donnelly, Peter J, Frayling, Timothy M, Sladek, Rob, Froguel, Philippe, Hansen, Torben, Kathiresan, Sekar, Barroso, Inês, Langenberg, Claudia, Wareham, Nicholas J, O'Callaghan, Christopher A, Gloyn, Anna L, Altshuler, David, Boehnke, Michael, Teslovich, Tanya M, Morris, Andrew P

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Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility von Wessel, Jennifer, Chu, Audrey Y, Willems, Sara M, Dauriz, Marco, Raghavan, Sridharan, Hidalgo, Bertha, An, Ping, Lu, Yingchang, Ehm, Margaret G, Baldridge, Abigail S, Freitag, Daniel F, Garcia, Melissa E, Hara, Kazuo, Jakobsdottir, Johanna, Lange, Leslie A, Layton, Jill C, Li, Man, Morrison, Alanna C, Peters, Marjolein J, Southam, Lorraine, Stoiber, Marcus H, Strawbridge, Rona J, Varga, Tibor V, Barbieri, Caterina, Bombieri, Cristina, Bowden, Donald W, Burns, Sean M, Chen, Yuning, Chen, Yii-DerI, Cheng, Ching-Yu, Ehret, Georg B, Eiriksdottir, Gudny, Escher, Stefan A, Frånberg, Mattias, Gambaro, Giovanni, Goel, Anuj, Grove, Megan L, Karaleftheri, Maria, Kirkpatrick, Andrea, Kraja, Aldi T, Kuusisto, Johanna, Lange, Ethan M, Lee, I T, Lee, Wen-Jane, Leong, Aaron, Liao, Jiemin, Lindgren, Cecilia M, Malerba, Giovanni, Mamakou, Vasiliki, Maruthur, Nisa M, McLeod, Olga, Mohlke, Karen L, Muzny, Donna M, Renström, Frida, Rice, Ken, Sala, Cinzia F, Soranzo, Nicole, Speliotes, Elizabeth K, Stirrups, Kathleen, Thanopoulou, Anastasia, Traglia, Michela, Tsafantakis, Emmanouil, Javad, Sundas, Yanek, Lisa R, Becker, Diane M, Bis, Joshua C, Brown, James B, Ingelsson, Erik, Karter, Andrew J, Lorenzo, Carlos, Peloso, Gina M, Vaidya, Dhananjay, Varma, Rohit, Wagenknecht, Lynne E, Dedoussis, George, Deloukas, Panos, Franco, Oscar H, Gibbs, Richard A, Gudnason, Vilmundur, Hofman, Albert, Jansson, Jan-Håkan, Langenberg, Claudia, Launer, Lenore J, Levy, Daniel, Oostra, Ben A, Padmanabhan, Sandosh, Pankow, James S, Rudan, Igor, Schulze, Matthias B, Smith, Blair H, Walker, Mark, Wong, Tien Y, Laakso, Markku, Borecki, Ingrid B, van Duijn, Cornelia M, Waterworth, Dawn M, Loos, Ruth J.F., Meigs, James B, Scott, Robert A, Goodarzi, Mark O

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Generalizability of a Diabetes-Associated Country-Specific Exploratory Dietary Pattern Is Feasible Across European Populations von Jannasch, Franziska, Kröger, Janine, Agnoli, Claudia, Barricarte, Aurelio, Boeing, Heiner, Cayssials, Valerie, Colorado-Yohar, Sandra, Dahm, Christina C, Dow, Courtney, Fagherazzi, Guy, Franks, Paul W, Freisling, Heinz, Gunter, Marc J, Nicola, D, Key, Timothy J, Khaw, Kay-Tee, Kühn, Tilman, Kyro, Cecilie, Mancini, Francesca Romana, Mokoroa, Olatz, Nilsson, Peter, Overvad, Kim, Palli, Domenico, Panico, Salvatore, García, Jose Ramón Quirós, Rolandsson, Olov, Sacerdote, Carlotta, Sánchez, Mariá-José, Sahrai, Mohammad Sediq, Schübel, Ruth, Sluijs, Ivonne, Spijkerman, Annemieke M W, Tjonneland, Anne, Tong, Tammy Y N, Tumino, Rosario, Riboli, Elio, Langenberg, Claudia, Sharp, Stephen J, Forouhi, Nita G, Schulze, Matthias B, Wareham, Nicholas J

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