Discovery of Small Molecule Splicing Modulators of Survival Motor Neuron‑2 (SMN2) for the Treatment of Spinal Muscular Atrophy (SMA) von Cheung, Atwood K, Hurley, Brian, Kerrigan, Ryan, Shu, Lei, Chin, Donovan N, Shen, Yiping, O’Brien, Gary, Sung, Moo Je, Hou, Ying, Axford, Jake, Cody, Emma, Sun, Robert, Fazal, Aleem, Tomlinson, Ronald C, Jain, Monish, Deng, Lin, Hoffmaster, Keith, Song, Cheng, Van Hoosear, Mailin, Shin, Youngah, Servais, Rebecca, Towler, Christopher, Hild, Marc, Curtis, Daniel, Dietrich, William F, Hamann, Lawrence G, Briner, Karin, Chen, Karen S, Kobayashi, Dione, Sivasankaran, Rajeev, Dales, Natalie A

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A molecular glue degrader of the WIZ transcription factor for fetal hemoglobin induction von Ting, Pamela Y, Borikar, Sneha, Kerrigan, John Ryan, Thomsen, Noel M, Aghania, Eamon, Hinman, Amelia E, Reyes, Alejandro, Pizzato, Nicolas, Fodor, Barna D, Wu, Fabian, Belew, Muluken S, Mao, Xiaohong, Wang, Jian, Chitnis, Shripad, Niu, Wei, Hachey, Amanda, Cobb, Jennifer S, Savage, Nikolas A, Burke, Ashley, Paulk, Joshiawa, Dovala, Dustin, Lin, James, Clifton, Matthew C, Ornelas, Elizabeth, Ma, Xiaolei, Ware, Nathaniel F, Sanchez, Carina C, Taraszka, John, Terranova, Remi, Knehr, Judith, Altorfer, Marc, Barnes, S Whitney, Beckwith, Rohan E J, Solomon, Jonathan M, Dales, Natalie A, Patterson, Andrew W, Wagner, Jürgen, Bouwmeester, Tewis, Dranoff, Glenn, Stevenson, Susan C, Bradner, James E

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Antibacterial and Solubility Optimization of Thiomuracin A von LaMarche, Matthew J, Leeds, Jennifer A, Brewer, Jason, Dean, Karl, Ding, Jian, Dzink-Fox, Joanne, Gamber, Gabe, Jain, Akash, Kerrigan, Ryan, Krastel, Philipp, Lee, Kwangho, Lombardo, Franco, McKenney, David, Neckermann, Georg, Osborne, Colin, Palestrant, Deborah, Patane, Michael A, Rann, Elin M, Robinson, Zachary, Schmitt, Esther, Stams, Travis, Tiamfook, Stacey, Yu, Donghui, Whitehead, Lewis

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Discovery and Optimization of First-in-Class Molecular Glue Degraders of the WIZ Transcription Factor for Fetal Hemoglobin Induction to Treat Sickle Cell Disease von Kerrigan, John Ryan, Thomsen, Noel M., Cernijenko, Artiom, Kochanek, Sarah E., Dewhurst, Janetta, O’Brien, Gary, Ware, Nathaniel F., Sanchez, Carina C., Manning, James R., Ma, Xiaolei, Ornelas, Elizabeth, Savage, Nikolas A., Partridge, James R., Patterson, Andrew W., Lam, Philip, Dales, Natalie A., Bonazzi, Simone, Borikar, Sneha, Hinman, Amelia E., Ting, Pamela Y.

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Targeted Degradation of the Wiz Transcription Factor for Gamma Globin De-Repression von Ting, Pamela Y, Borikar, Sneha, Kerrigan, John Ryan, Thomsen, Noel M, Aghania, Eamon, Hinman, Amelia E, Pizzato, Nicolas, Reyes, Alejandro, Fodor, Barna D, Wu, Fabian, Belew, Muluken S, Mao, Xiaohong, Wang, Jian, Chitnis, Shripad, Ashcroft, Peter, Niu, Wei, Hachey, Amanda, Cobb, Jennifer S, Savage, Nikolas A, Burke, Ashley, Paulk, Joshiawa, Dovala, Dustin, Lin, James, Clifton, Matthew C, Ornelas, Elizabeth, Ma, Xiaolei, Ware, Nathaniel F, Sanchez, Carina C, Terranova, Remi, Knehr, Judith, Altorfer, Marc, Barnes, S. Whitney, Taraszka, John, Lubicka, Danuta, Manning, James R, Miranda, Sonia R, Beckwith, Rohan EJ, Solomon, Jonathan M, Forrester, William, Hollingworth, Gregory, Dales, Natalie A, Patterson, Andrew W, Bouwmeester, Tewis, Wagner, Juergen, Dranoff, Glenn, Stevenson, Susan C, Bradner, James E

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DIPHENYL DERIVATIVES AND USES THEREOF von DALES, Natalie, GORMISKY, Paul, KERRIGAN, John Ryan, SHU, Lei

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Derivados de 3-(1-oxoisoindolin-2-il)piperidina-2,6-diona y sus usos médicos von MooJe SUNG, Noel Marie-France THOMSEN, Simone BONAZZI, Gary O'BRIEN, Jennifer Stroka COBB, John Ryan KERRIGAN, Artiom CERNIJENKO, Pamela YF TING, Janetta DEWHURST

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3-(5-oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione Derivatives and Uses thereof von SUNG, MooJe, COBB, Jennifer Stroka, O'BRIEN, Gary, CERNIJENKO, Artiom, BONAZZI, Simone, DEWHURST, Janetta, KERRIGAN, John Ryan, TING, Pamela, THOMSEN, Noel Marie-France

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PYRAZOLOPYRIDINE DERIVATIVES AND USES THEREOF von HESSE, Matthew James, COBB, Jennifer Stroka, DALES, Natalie Alysia, BONAZZI, Simone, KERRIGAN, John Ryan, TING, Pamela YF, MANNING, James R, JAIN, Rama, MALIK, Hasnain Ahmed

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Derivados de 3-(5-oxoisoindolin-2-il)piperidina-2,6-diona e seus usos von JOHN RYAN KERRIGAN, BONAZZI SIMONE, PAMELA YF TING, CERNIJENKO ARTIOM, DEWHURST JANETTA, NOEL MARIE-FRANCE THOMSEN, JENNIFER STROKA COBB, SUNG MOOJE, O'BRIEN GARY

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3-(5-oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof von Dewhurst, Janetta, Bonazzi, Simone, O'Brien, Gary, Ting, Pamela, Thomsen, Noel Marie-France, Sung, MooJe, Cernijenko, Artiom, Kerrigan, John Ryan, Cobb, Jennifer Stroka

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DERIVADOS DE 3–(1–OXOISOINDOLIN–2–IL)PIPERIDINA–2,6–DIONA Y SUS USOS MÉDICOS von GARY O'BRIEN, JOHN RYAN KERRIGAN, PAMELA YF TING, NOEL MARIE-FRANCE THOMSEN, JANETTA DEWHURST, SIMONE BONAZZI, MOOJE SUNG, JENNIFER STROKA COBB, ARTIOM CERNIJENKO

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INDOLE DERIVATIVES AND USES THEREOF von DALES, Natalie, GORMISKY, Paul, PALACIOS, Daniel, TRIA, George, Scott, KERRIGAN, John, Ryan

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Phosphaturic effect of L-NMMA in the presence of parathyroid hormone von Onsgard-Meyer, M. J, Kerrigan, R. J, Collins, M, Khraibi, A. A, Knox, F. G

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3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND MEDICAL USES THEREOF von SUNG, MooJe, COBB, Jennifer Stroka, O'BRIEN, Gary, CERNIJENKO, Artiom, BONAZZI, Simone, DEWHURST, Janetta, KERRIGAN, John Ryan, TING, Pamela YF, THOMSEN, Noel Marie-France

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3-(5-METHOXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF von LAM, Philip, COBB, Jennifer Stroka, O'BRIEN, Gary, CERNIJENKO, Artiom, DALES, Natalie, PATTERSON, Andrew W, BONAZZI, Simone, KERRIGAN, John Ryan, TING, Pamela, MALIK, Hasnain Ahmed, THOMSEN, Noel Marie-france

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DIPHENYL DERIVATIVES AND USES THEREOF von DALES, Natalie, GORMISKY, Paul, KERRIGAN, John Ryan, SHU, Lei

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Pyrazolopyridine derivatives and uses thereof von HESSE, Matthew James, COBB, Jennifer Stroka, CERNIJENKO, Artiom, DEWHURST, Janetta, KERRIGAN, John Ryan, TING, Pamela YF, MANNING, James R, JAIN, Rama, THOMSEN, Noel Marie-France, O'BRIEN, Gary, DALES, Natalie Alysia, PATTERSON, Andrew W, BONAZZI, Simone, MALIK, Hasnain Ahmed

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Derivados de pirazolopiridina y sus usos von Rama JAIN, Andrew W. PATTERSON, Jennifer Stroka COBB, Artiom CERNIJENKO, Hasnain Ahmed MALIK, Matthew James HESSE, Noel Marie-France THOMSEN, Simone BONAZZI, Gary O'BRIEN, John Ryan KERRIGAN, James R. MANNING, Natalie Alysia DALES, Pamela YF TING, Janetta DEWHURST

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Pyrazolopyridine derivatives and uses thereof von Hesse, Matthew James, Ting, Pamela Yf, Thomsen, Noel Marie-France, Manning, James R, Cernijenko, Artiom, Kerrigan, John Ryan, Cobb, Jennifer Stroka, Dewhurst, Janetta, Jain, Rama, Bonazzi, Simone, Dales, Natalie Alysia, Patterson, Andrew W, O'Brien, Gary, Malik, Hasnain Ahmed

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