Somatic mutations in lymphocytes in patients with immune-mediated aplastic anemia von Lundgren, Sofie, Keränen, Mikko A. I., Kankainen, Matti, Huuhtanen, Jani, Walldin, Gunilla, Kerr, Cassandra M., Clemente, Michael, Ebeling, Freja, Rajala, Hanna, Brück, Oscar, Lähdesmäki, Harri, Hannula, Sari, Hannunen, Tiina, Ellonen, Pekka, Young, Neal S., Ogawa, Seishi, Maciejewski, Jaroslaw P., Hellström-Lindberg, Eva, Mustjoki, Satu

Volltext

Enrichment of cancer-predisposing germline variants in adult and pediatric patients with acute lymphoblastic leukemia von Douglas, Suvi P. M., Lahtinen, Atte K., Koski, Jessica R., Leimi, Lilli, Keränen, Mikko A. I., Koskenvuo, Minna, Heckman, Caroline A., Jahnukainen, Kirsi, Pitkänen, Esa, Wartiovaara-Kautto, Ulla, Kilpivaara, Outi

Volltext

Gemtuzumab-Ozogamicin-Related Impaired Hemoglobin-Haptoglobin Scavenging as On-Target/Off-Tumor Toxicity of Anti-CD33 AML Therapy: A Report of Two Cases von Rajala, Hanna L. M., Anttila, Veli-Jukka, Haapio, Mikko, Keränen, Mikko A. I., Wartiovaara-Kautto, Ulla, Räty, Riikka

Volltext

Clonal hematopoiesis in patients with rheumatoid arthritis von Savola, Paula, Lundgren, Sofie, Keränen, Mikko A. I., Almusa, Henrikki, Ellonen, Pekka, Leirisalo-Repo, Marjatta, Kelkka, Tiina, Mustjoki, Satu

Volltext

Somatic mTOR mutation in clonally expanded T lymphocytes associated with chronic graft versus host disease von Kim, Daehong, Park, Giljun, Huuhtanen, Jani, Lundgren, Sofie, Khajuria, Rajiv K., Hurtado, Ana M., Muñoz-Calleja, Cecilia, Cardeñoso, Laura, Gómez-García de Soria, Valle, Chen-Liang, Tzu Hua, Eldfors, Samuli, Ellonen, Pekka, Hannula, Sari, Kankainen, Matti, Bruck, Oscar, Kreutzman, Anna, Salmenniemi, Urpu, Lönnberg, Tapio, Jerez, Andrés, Itälä-Remes, Maija, Myllymäki, Mikko, Keränen, Mikko A. I., Mustjoki, Satu

Volltext

Targeting Lymphatic Vessel Activation and CCL21 Production by Vascular Endothelial Growth Factor Receptor-3 Inhibition Has Novel Immunomodulatory and Antiarteriosclerotic Effects i... von NYKÄNEN, Antti I, SANDELIN, Henrik, ALITALO, Kari, LEMSTRÖM, Karl B, KREBS, Rainer, KERÄNEN, Mikko A. I, TUUMINEN, Raimo, KÄRPÄNEN, Terhi, YAN WU, PYTOWSKI, Bronislaw, KOSKINEN, Petri K, YLÄ-HERTTUALA, Seppo

Volltext

Donor Simvastatin Treatment Abolishes Rat Cardiac Allograft Ischemia/Reperfusion Injury and Chronic Rejection Through Microvascular Protection von TUUMINEN, Raimo, SYRJALA, Simo, KREBS, Rainer, KERÄNEN, Mikko A. I, KOLI, Katri, ABO-RAMADAN, Usama, NEUVONEN, Pertti J, TIKKANEN, Jussi M, NYKANEN, Antti I, LEMSTRÖM, Karl B

Volltext

Ex vivo intracoronary gene transfer of adeno‐associated virus 2 leads to superior transduction over serotypes 8 and 9 in rat heart transplants von Raissadati, Alireza, Jokinen, Janne J., Syrjälä, Simo O., Keränen, Mikko A. I., Krebs, Rainer, Tuuminen, Raimo, Arnaudova, Ralica, Rouvinen, Eeva, Anisimov, Andrey, Soronen, Jarkko, Pajusola, Katri, Alitalo, Kari, Nykänen, Antti I., Lemström, Karl

Volltext

Integrated drug profiling and CRISPR screening identify essential pathways for CAR T-cell cytotoxicity von Dufva, Olli, Koski, Jan, Maliniemi, Pilvi, Ianevski, Aleksandr, Klievink, Jay, Leitner, Judith, Pölönen, Petri, Hohtari, Helena, Saeed, Khalid, Hannunen, Tiina, Ellonen, Pekka, Steinberger, Peter, Kankainen, Matti, Aittokallio, Tero, Keränen, Mikko A.I., Korhonen, Matti, Mustjoki, Satu

Volltext

Platelet-derived Growth Factor-B Protects Rat Cardiac Allografts From Ischemia-reperfusion Injury von Tuuminen, Raimo, Dashkevich, Alexey, Keränen, Mikko A I, Raissadati, Alireza, Krebs, Rainer, Jokinen, Janne J, Arnaudova, Ralica, Rouvinen, Eeva, Ylä-Herttuala, Seppo, Nykänen, Antti I, Lemström, Karl B

Volltext

Author Correction: Clonal hematopoiesis in patients with rheumatoid arthritis von Savola, Paula, Lundgren, Sofie, Keränen, Mikko A. I., Almusa, Henrikki, Ellonen, Pekka, Leirisalo-Repo, Marjatta, Kelkka, Tiina, Mustjoki, Satu

Volltext

Somatic mutations and T-cell clonality in patients with immunodeficiency von Savola, Paula, Martelius, Timi, Kankainen, Matti, Huuhtanen, Jani, Lundgren, Sofie, Koski, Yrjo, Eldfors, Samuli, Kelkka, Tiina, Keranen, Mikko A. I., Ellonen, Pekka, Kovanen, Panu E., Kytola, Soili, Saarela, Janna, Lahdesmaki, Harri, Seppanen, Mikko R. J., Mustjoki, Satu

Volltext

Immunogenomic Landscape of Hematological Malignancies von Dufva, Olli, Pölönen, Petri, Brück, Oscar, Keränen, Mikko A.I., Klievink, Jay, Mehtonen, Juha, Huuhtanen, Jani, Kumar, Ashwini, Malani, Disha, Siitonen, Sanna, Kankainen, Matti, Ghimire, Bishwa, Lahtela, Jenni, Mattila, Pirkko, Vähä-Koskela, Markus, Wennerberg, Krister, Granberg, Kirsi, Leivonen, Suvi-Katri, Meriranta, Leo, Heckman, Caroline, Leppä, Sirpa, Nykter, Matti, Lohi, Olli, Heinäniemi, Merja, Mustjoki, Satu

Volltext

Common Protective and Diverse Smooth Muscle Cell Effects of AAV-Mediated Angiopoietin-1 and -2 Expression in Rat Cardiac Allograft Vasculopathy von Nykänen, Antti I, Pajusola, Katri, Krebs, Rainer, Keränen, Mikko A.I, Raisky, Olivier, Koskinen, Petri K, Alitalo, Kari, Lemström, Karl B

Volltext

Angiogenic growth factors in cardiac allograft rejection von NYKÄNEN, Antti I, TIKKANEN, Jussi M, KREBS, Rainer, KERÄNEN, Mikko A. I, SIHVOLA, Roope K, SANDELIN, Henrik, TUUMINEN, Raimo, RAISKY, Olivier, KOSKINEN, Petri K, LEMSTRÖM, Karl B

Volltext

VEGFR-1 and -2 Regulate Inflammation, Myocardial Angiogenesis, and Arteriosclerosis in Chronically Rejecting Cardiac Allografts von Raisky, Olivier, Nykänen, Antti I, Krebs, Rainer, Hollmén, Maria, Keränen, Mikko A.I, Tikkanen, Jussi M, Sihvola, Roope, Alhonen, Leena, Salven, Petri, Wu, Yan, Hicklin, Daniel J, Alitalo, Kari, Koskinen, Petri K, Lemström, Karl B

Volltext

Somatic mutations associate with clonal expansion of CD8 + T cells von Lundgren, Sofie, Myllymäki, Mikko, Järvinen, Timo, Keränen, Mikko A I, Theodoropoulos, Jason, Smolander, Johannes, Kim, Daehong, Salmenniemi, Urpu, Walldin, Gunilla, Savola, Paula, Kelkka, Tiina, Rajala, Hanna, Hellström-Lindberg, Eva, Itälä-Remes, Maija, Kankainen, Matti, Mustjoki, Satu

Volltext

Hypoxia‐inducible factor controls immunoregulatory properties of myeloid cells in mouse cardiac allografts – an experimental study von Keränen, Mikko A. I., Raissadati, Alireza, Nykänen, Antti I., Dashkevich, Alexey, Tuuminen, Raimo, Krebs, Rainer, Johnson, Randall S., Syrjälä, Simo O., Lemström, Karl B.

Volltext

PDGF-A, -C, and -D but not PDGF-B Increase TGF-β1 and Chronic Rejection in Rat Cardiac Allografts von TUUMINEN, Raimo, NYKÄNEN, Antti I, KREBS, Rainer, SORONEN, Jarkko, PAJUSOLA, Katri, KERÄNEN, Mikko A. I, KOSKINEN, Petri K, ALITALO, Kari, LEMSTRÖM, Karl B

Volltext

Increased Th17 rather than Th1 alloimmune response is associated with cardiac allograft vasculopathy after hypothermic preservation in the rat von Syrjälä, Simo O., MD, Keränen, Mikko A.I., MD, Tuuminen, Raimo, MD, Nykänen, Antti I., MD, Tammi, Markku, MD, PhD, Krebs, Rainer, MS, Lemström, Karl B., MD, PhD

Volltext