Preparation of (3R)-quinuclidinol using heterogeneous biocatalytic hydrogenation in a dynamically-mixed continuous flow reactor von Cleary, Sarah E., Kazantzi, Sofia, Trenchard, Joshua A., Monedero, Martin, Allman, Jack W., Lurshay, Tara C., Zhao, Xu, Kenny, Michael B. C., Reeve, Holly A.

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Negative feedback control of neuronal activity by microglia von Badimon, Ana, Strasburger, Hayley J., Ayata, Pinar, Chen, Xinhong, Nair, Aditya, Ikegami, Ako, Hwang, Philip, Chan, Andrew T., Graves, Steven M., Uweru, Joseph O., Ledderose, Carola, Kutlu, Munir Gunes, Wheeler, Michael A., Kahan, Anat, Ishikawa, Masago, Wang, Ying-Chih, Loh, Yong-Hwee E., Jiang, Jean X., Surmeier, D. James, Robson, Simon C., Junger, Wolfgang G., Sebra, Robert, Calipari, Erin S., Kenny, Paul J., Eyo, Ukpong B., Colonna, Marco, Quintana, Francisco J., Wake, Hiroaki, Gradinaru, Viviana, Schaefer, Anne

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De Novo Gene Disruptions in Children on the Autistic Spectrum von Iossifov, Ivan, Ronemus, Michael, Levy, Dan, Wang, Zihua, Hakker, Inessa, Rosenbaum, Julie, Yamrom, Boris, Lee, Yoon-ha, Narzisi, Giuseppe, Leotta, Anthony, Kendall, Jude, Grabowska, Ewa, Ma, Beicong, Marks, Steven, Rodgers, Linda, Stepansky, Asya, Troge, Jennifer, Andrews, Peter, Bekritsky, Mitchell, Pradhan, Kith, Ghiban, Elena, Kramer, Melissa, Parla, Jennifer, Demeter, Ryan, Fulton, Lucinda L., Fulton, Robert S., Magrini, Vincent J., Ye, Kenny, Darnell, Jennifer C., Darnell, Robert B., Mardis, Elaine R., Wilson, Richard K., Schatz, Michael C., McCombie, W. Richard, Wigler, Michael

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Genome-wide polygenic score to predict chronic kidney disease across ancestries von Khan, Atlas, Turchin, Michael C., Patki, Amit, Srinivasasainagendra, Vinodh, Shang, Ning, Nadukuru, Rajiv, Jones, Alana C., Malolepsza, Edyta, Dikilitas, Ozan, Kullo, Iftikhar J., Schaid, Daniel J., Karlson, Elizabeth, Ge, Tian, Meigs, James B., Smoller, Jordan W., Lange, Christoph, Crosslin, David R., Jarvik, Gail P., Bhatraju, Pavan K., Hellwege, Jacklyn N., Chandler, Paulette, Torvik, Laura Rasmussen, Fedotov, Alex, Liu, Cong, Kachulis, Christopher, Lennon, Niall, Abul-Husn, Noura S., Cho, Judy H., Ionita-Laza, Iuliana, Gharavi, Ali G., Chung, Wendy K., Hripcsak, George, Weng, Chunhua, Nadkarni, Girish, Irvin, Marguerite R., Tiwari, Hemant K., Kenny, Eimear E., Limdi, Nita A., Kiryluk, Krzysztof

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Outpatient treatment of COVID-19 and incidence of post-COVID-19 condition over 10 months (COVID-OUT): a multicentre, randomised, quadruple-blind, parallel-group, phase 3 trial von Bramante, Carolyn T, Buse, John B, Liebovitz, David M, Nicklas, Jacinda M, Puskarich, Michael A, Cohen, Ken, Belani, Hrishikesh K, Anderson, Blake J, Tignanelli, Christopher J, Thompson, Jennifer L, Pullen, Matthew, Wirtz, Esteban Lemus, Siegel, Lianne K, Proper, Jennifer L, Odde, David J, Klatt, Nichole R, Lindberg, Sarah M, Karger, Amy B, Erickson, Spencer M, Fenno, Sarah L, Hartman, Katrina M, Rose, Michael R, Mehta, Tanvi, Patel, Barkha, Griffiths, Gwendolyn, Bhat, Neeta S, Murray, Thomas A, Boulware, David R, Anderson, Blake, Atwater, Riannon C, Avula, Nandini, Beckman, Kenny B, Belani, Hrishikesh K, Boulware, David R, Bramante, Carolyn T, Brea, Jannis, Broedlow, Courtney A, Buse, John B, Campora, Paula, Challa, Anup, Charles, Jill, Christensen, Grace, Christiansen, Theresa, Cohen, Ken, Connelly, Bo, Datta, Srijani, Deng, Nikita, Dunn, Alex T, Erickson, Spencer M, Fairbairn, Faith M, Fenno, Sarah L, Fraser, Daniel J, Fricton, Regina D, Griffiths, Gwen, Hagen, Aubrey A, Hartman, Katrina M, Hendrickson, Audrey F, Huling, Jared D, Ingraham, Nicholas E, Jeng, Arthur C, Johnson, Darrell M, Karger, Amy B, Klatt, Nichole R, LaBar, Derek D, Lee, Samuel, Liebovitz, David M, Lindberg, Sarah, Luke, Darlette G, Machicado, Rosario, Mohamud, Zeinab, Murray, Thomas A, Ngonyama, Rumbidzai, Nicklas, Jacinda M, Odde, David J, Parrens, Elliott, Parra, Daniela, Patel, Barkha, Proper, Jennifer L, Pullen, Matthew F, Puskarich, Michael A, Rao, Via, Reddy, Neha V, Reddy, Naveen, Rypka, Katelyn J, Saveraid, Hanna G, Seloadji, Paula, Shahriar, Arman, Sherwood, Nancy, Siegart, Jamie L, Siegel, Lianne K, Simmons, Lucas, Sinelli, Isabella, Snyder, Andrew, Stauffer, Maxwell T, Tignanelli, Christopher J, Watson, Ray HB, Wu, Beiqing, Zaman, Adnin, Zolik, Madeline R, Zinkl, Lena

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Minimization of Childhood Maltreatment Is Common and Consequential: Results from a Large, Multinational Sample Using the Childhood Trauma Questionnaire von MacDonald, Kai, Thomas, Michael L, Sciolla, Andres F, Schneider, Beacher, Pappas, Katherine, Bleijenberg, Gijs, Bohus, Martin, Bekh, Bradley, Carpenter, Linda, Carr, Alan, Dannlowski, Udo, Dorahy, Martin, Fahlke, Claudia, Finzi-Dottan, Ricky, Karu, Tobi, Gerdner, Arne, Glaesmer, Heide, Grabe, Hans Jörgen, Heins, Marianne, Kenny, Dianna T, Kim, Daeho, Knoop, Hans, Lobbestael, Jill, Lochner, Christine, Lauritzen, Grethe, Ravndal, Edle, Riggs, Shelley, Sar, Vedat, Schäfer, Ingo, Schlosser, Nicole, Schwandt, Melanie L, Stein, Murray B, Subic-Wrana, Claudia, Vogel, Mark, Wingenfeld, Katja

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The Chandra Source Catalog von Evans, Ian N, Primini, Francis A, Glotfelty, Kenny J, Anderson, Craig S, Bonaventura, Nina R, Chen, Judy C, Davis, John E, Doe, Stephen M, Evans, Janet D, Fabbiano, Giuseppina, Galle, Elizabeth C, Gibbs, Danny G, Grier, John D, Hain, Roger M, Hall, Diane M, Harbo, Peter N, He, Xiangqun (Helen), Houck, John C, Karovska, Margarita, Kashyap, Vinay L, Lauer, Jennifer, McCollough, Michael L, McDowell, Jonathan C, Miller, Joseph B, Mitschang, Arik W, Morgan, Douglas L, Mossman, Amy E, Nichols, Joy S, Nowak, Michael A, Plummer, David A, Refsdal, Brian L, Rots, Arnold H, Siemiginowska, Aneta, Sundheim, Beth A, Tibbetts, Michael S, Van Stone, David W, Winkelman, Sherry L, Zografou, Panagoula

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Diverse inhibitor chemotypes targeting Trypanosoma cruzi CYP51 von Gunatilleke, Shamila S, Calvet, Claudia M, Johnston, Jonathan B, Chen, Chiung-Kuang, Erenburg, Grigori, Gut, Jiri, Engel, Juan C, Ang, Kenny K H, Mulvaney, Joseph, Chen, Steven, Arkin, Michelle R, McKerrow, James H, Podust, Larissa M

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Early Pregnancy Prediction of Preeclampsia in Nulliparous Women, Combining Clinical Risk and Biomarkers: The Screening for Pregnancy Endpoints (SCOPE) International Cohort Study von KENNY, Louise C, BLACK, Michael A, RODEMS, Kelline, NOLAND, Brian, RAYMUNDO, Michael, WALKER, James J, NORTH, Robyn A, POSTON, Lucilla, TAYLOR, Rennae, MYERS, Jenny E, BAKER, Philip N, MCCOWAN, Lesley M, SIMPSON, Nigel A. B, DEKKER, Gus A, ROBERTS, Claire T

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Prospective, Multicenter, Controlled Trial of Mobile Stroke Units von Grotta, James C, Yamal, Jose-Miguel, Parker, Stephanie A, Rajan, Suja S, Gonzales, Nicole R, Jones, William J, Alexandrov, Anne W, Navi, Babak B, Nour, May, Spokoyny, Ilana, Mackey, Jason, Persse, David, Jacob, Asha P, Wang, Mengxi, Singh, Noopur, Alexandrov, Andrei V, Fink, Matthew E, Saver, Jeffrey L, English, Joey, Barazangi, Nobl, Bratina, Patti L, Gonzalez, Michael, Schimpf, Brandi D, Ackerson, Kim, Sherman, Carla, Lerario, Mackenzie, Mir, Saad, Im, Jenny, Willey, Josh Z, Chiu, David, Eisshofer, Michael, Miller, Janice, Ornelas, David, Rhudy, James P, Brown, Kevin M, Villareal, Bryan M, Gausche-Hill, Marianne, Bosson, Nichole, Gilbert, Greg, Collins, Sarah Q, Silnes, Kelly, Volpi, Jay, Misra, Vivek, McCarthy, James, Flanagan, Tom, Rao, Chethan P.V, Kass, Joseph S, Griffin, Laura, Rangel-Gutierrez, Nicole, Lechuga, Edgar, Stephenson, Jonathan, Phan, Kenny, Sanders, Yvette, Noser, Elizabeth A, Bowry, Ritvij

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Once-Daily Opioids for Chronic Dyspnea: A Dose Increment and Pharmacovigilance Study von Currow, David C., BMed, MPH, FRACP, McDonald, Christine, MBBS, PhD, FRACP, Oaten, Sheila, RN, Kenny, Bernadette, BEc, RN, Allcroft, Peter, BMBS, FRACP, Frith, Peter, MBBS, PhD, FRACP, Briffa, Michael, BMBS, FRACGP, FAChPM, Johnson, Miriam J., MB ChB, MD, FRCP, MRCGP, Abernethy, Amy P., MD

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Cells of the human intestinal tract mapped across space and time von Elmentaite, Rasa, Kumasaka, Natsuhiko, Roberts, Kenny, Fleming, Aaron, Dann, Emma, King, Hamish W., Kleshchevnikov, Vitalii, Dabrowska, Monika, Pritchard, Sophie, Bolt, Liam, Vieira, Sara F., Mamanova, Lira, Huang, Ni, Perrone, Francesca, Goh Kai’En, Issac, Lisgo, Steven N., Katan, Matilda, Leonard, Steven, Oliver, Thomas R. W., Hook, C. Elizabeth, Nayak, Komal, Campos, Lia S., Domínguez Conde, Cecilia, Stephenson, Emily, Engelbert, Justin, Botting, Rachel A., Polanski, Krzysztof, van Dongen, Stijn, Patel, Minal, Morgan, Michael D., Marioni, John C., Bayraktar, Omer Ali, Meyer, Kerstin B., He, Xiaoling, Barker, Roger A., Uhlig, Holm H., Mahbubani, Krishnaa T., Saeb-Parsy, Kourosh, Zilbauer, Matthias, Clatworthy, Menna R., Haniffa, Muzlifah, James, Kylie R., Teichmann, Sarah A.

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Mapping and characterization of structural variation in 17,795 human genomes von Abel, Haley J., Larson, David E., Regier, Allison A., Chiang, Colby, Das, Indraniel, Kanchi, Krishna L., Layer, Ryan M., Neale, Benjamin M., Salerno, William J., Reeves, Catherine, Buyske, Steven, Matise, Tara C., Muzny, Donna M., Zody, Michael C., Lander, Eric S., Dutcher, Susan K., Stitziel, Nathan O., Hall, Ira M.

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Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility von O'Dushlaine, C, Kenny, E, Heron, E, Donohoe, G, Gill, M, Morris, D, Corvin, A

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Randomized Trial of Metformin, Ivermectin, and Fluvoxamine for Covid-19 von Bramante, Carolyn T., Huling, Jared D., Tignanelli, Christopher J., Buse, John B., Liebovitz, David M., Nicklas, Jacinda M., Cohen, Kenneth, Puskarich, Michael A., Belani, Hrishikesh K., Proper, Jennifer L., Siegel, Lianne K., Klatt, Nichole R., Odde, David J., Luke, Darlette G., Anderson, Blake, Karger, Amy B., Ingraham, Nicholas E., Hartman, Katrina M., Rao, Via, Hagen, Aubrey A., Patel, Barkha, Fenno, Sarah L., Avula, Nandini, Reddy, Neha V., Erickson, Spencer M., Lindberg, Sarah, Fricton, Regina, Lee, Samuel, Zaman, Adnin, Saveraid, Hanna G., Tordsen, Walker J., Pullen, Matthew F., Biros, Michelle, Sherwood, Nancy E., Thompson, Jennifer L., Boulware, David R., Murray, Thomas A.

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Considerations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA In Vitro Respon... von Kenny, Jane R., Ramsden, Diane, Buckley, David B., Dallas, Shannon, Fung, Conrad, Mohutsky, Michael, Einolf, Heidi J., Chen, Liangfu, Dekeyser, Joshua G., Fitzgerald, Maria, Goosen, Theunis C., Siu, Y. Amy, Walsky, Robert L., Zhang, George, Tweedie, Donald, Hariparsad, Niresh

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A genomic mutational constraint map using variation in 76,156 human genomes von Chen, Siwei, Francioli, Laurent C., Goodrich, Julia K., Collins, Ryan L., Kanai, Masahiro, Wang, Qingbo, Alföldi, Jessica, Watts, Nicholas A., Vittal, Christopher, Gauthier, Laura D., Poterba, Timothy, Wilson, Michael W., Tarasova, Yekaterina, Phu, William, Grant, Riley, Yohannes, Mary T., Koenig, Zan, Farjoun, Yossi, Banks, Eric, Donnelly, Stacey, Gabriel, Stacey, Gupta, Namrata, Ferriera, Steven, Tolonen, Charlotte, Novod, Sam, Bergelson, Louis, Roazen, David, Ruano-Rubio, Valentin, Covarrubias, Miguel, Llanwarne, Christopher, Petrillo, Nikelle, Wade, Gordon, Jeandet, Thibault, Munshi, Ruchi, Tibbetts, Kathleen, O’Donnell-Luria, Anne, Solomonson, Matthew, Seed, Cotton, Martin, Alicia R., Talkowski, Michael E., Rehm, Heidi L., Daly, Mark J., Tiao, Grace, Neale, Benjamin M., MacArthur, Daniel G., Karczewski, Konrad J.

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Leptin Directly Activates SF1 Neurons in the VMH, and This Action by Leptin Is Required for Normal Body-Weight Homeostasis von Dhillon, Harveen, Zigman, Jeffrey M., Ye, Chianping, Lee, Charlotte E., McGovern, Robert A., Tang, Vinsee, Kenny, Christopher D., Christiansen, Lauryn M., White, Ryan D., Edelstein, Elisabeth A., Coppari, Roberto, Balthasar, Nina, Cowley, Michael A., Chua, Streamson, Elmquist, Joel K., Lowell, Bradford B.

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A Multicomponent Animal Virus Isolated from Mosquitoes von Ladner, Jason T., Wiley, Michael R., Beitzel, Brett, Auguste, Albert J., Dupuis, Alan P., Lindquist, Michael E., Sibley, Samuel D., Kota, Krishna P., Fetterer, David, Eastwood, Gillian, Kimmel, David, Prieto, Karla, Guzman, Hilda, Aliota, Matthew T., Reyes, Daniel, Brueggemann, Ernst E., St. John, Lena, Hyeroba, David, Lauck, Michael, Friedrich, Thomas C., O’Connor, David H., Gestole, Marie C., Cazares, Lisa H., Popov, Vsevolod L., Castro-Llanos, Fanny, Kochel, Tadeusz J., Kenny, Tara, White, Bailey, Ward, Michael D., Loaiza, Jose R., Goldberg, Tony L., Weaver, Scott C., Kramer, Laura D., Tesh, Robert B., Palacios, Gustavo

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Time-crystalline eigenstate order on a quantum processor von Mi, Xiao, Ippoliti, Matteo, Quintana, Chris, Greene, Ami, Chen, Zijun, Gross, Jonathan, Arute, Frank, Arya, Kunal, Atalaya, Juan, Babbush, Ryan, Bardin, Joseph C., Basso, Joao, Bengtsson, Andreas, Bilmes, Alexander, Bourassa, Alexandre, Brill, Leon, Broughton, Michael, Buckley, Bob B., Buell, David A., Burkett, Brian, Bushnell, Nicholas, Chiaro, Benjamin, Collins, Roberto, Courtney, William, Debroy, Dripto, Demura, Sean, Derk, Alan R., Dunsworth, Andrew, Eppens, Daniel, Erickson, Catherine, Farhi, Edward, Fowler, Austin G., Foxen, Brooks, Gidney, Craig, Giustina, Marissa, Harrigan, Matthew P., Harrington, Sean D., Hilton, Jeremy, Ho, Alan, Hong, Sabrina, Huang, Trent, Huff, Ashley, Huggins, William J., Ioffe, L. B., Isakov, Sergei V., Iveland, Justin, Jeffrey, Evan, Jiang, Zhang, Jones, Cody, Kafri, Dvir, Khattar, Tanuj, Kim, Seon, Kitaev, Alexei, Klimov, Paul V., Korotkov, Alexander N., Kostritsa, Fedor, Landhuis, David, Laptev, Pavel, Lee, Joonho, Lee, Kenny, Locharla, Aditya, Lucero, Erik, Martin, Orion, McClean, Jarrod R., McCourt, Trevor, McEwen, Matt, Miao, Kevin C., Mohseni, Masoud, Mruczkiewicz, Wojciech, Naaman, Ofer, Neeley, Matthew, Neill, Charles, Newman, Michael, Niu, Murphy Yuezhen, O’Brien, Thomas E., Opremcak, Alex, Ostby, Eric, Pato, Balint, Petukhov, Andre, Rubin, Nicholas C., Sank, Daniel, Satzinger, Kevin J., Su, Yuan, Szalay, Marco, Trevithick, Matthew D., White, Theodore, Yao, Z. Jamie, Yeh, Ping, Yoo, Juhwan, Zalcman, Adam, Neven, Hartmut, Boixo, Sergio, Smelyanskiy, Vadim, Megrant, Anthony, Kelly, Julian, Chen, Yu, Sondhi, S. L., Kechedzhi, Kostyantyn, Khemani, Vedika, Roushan, Pedram

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