Inhibiting Plasma Kallikrein for Hereditary Angioedema Prophylaxis von Banerji, Aleena, Busse, Paula, Shennak, Mustafa, Lumry, William, Davis-Lorton, Mark, Wedner, Henry J, Jacobs, Joshua, Baker, James, Bernstein, Jonathan A, Lockey, Richard, Li, H. Henry, Craig, Timothy, Cicardi, Marco, Riedl, Marc, Al-Ghazawi, Ahmad, Soo, Carolyn, Iarrobino, Ryan, Sexton, Daniel J, TenHoor, Christopher, Kenniston, Jon A, Faucette, Ryan, Still, J. Gordon, Kushner, Harvey, Mensah, Robert, Stevens, Chris, Biedenkapp, Joseph C, Chyung, Yung, Adelman, Burt

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Dynamin GTPase regulation is altered by PH domain mutations found in centronuclear myopathy patients von Kenniston, Jon A, Lemmon, Mark A

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Comparison of Saccharomyces cerevisiae F-BAR Domain Structures Reveals a Conserved Inositol Phosphate Binding Site von Moravcevic, Katarina, Alvarado, Diego, Schmitz, Karl R., Kenniston, Jon A., Mendrola, Jeannine M., Ferguson, Kathryn M., Lemmon, Mark A.

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Inhibition of Plasma Kallikrein by a Highly Specific Active Site Blocking Antibody von Kenniston, Jon A., Faucette, Ryan R., Martik, Diana, Comeau, Stephen R., Lindberg, Allison P., Kopacz, Kris J., Conley, Gregory P., Chen, Jie, Viswanathan, Malini, Kastrapeli, Niksa, Cosic, Janja, Mason, Shauna, DiLeo, Mike, Abendroth, Jan, Kuzmic, Petr, Ladner, Robert C., Edwards, Thomas E., TenHoor, Christopher, Adelman, Burt A., Nixon, Andrew E., Sexton, Daniel J.

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Identification of small molecule agonists of fetal hemoglobin expression for the treatment of sickle cell disease von Yang, Jian-Ping, Toughiri, Rachel, Gounder, Anshu P, Scheibe, Dan, Petrus, Matt, Fink, Sarah J, Vallee, Sebastien, Kenniston, Jon, Papaioannou, Nikolaos, Langston, Steve, Gavva, Narender R, Horman, Shane R

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Linkage between ATP Consumption and Mechanical Unfolding during the Protein Processing Reactions of an AAA+ Degradation Machine von Kenniston, Jon A., Baker, Tania A., Fernandez, Julio M., Sauer, Robert T.

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A novel assay of excess plasma kallikrein-kinin system activation in hereditary angioedema von Sexton, Dan, Faucette, Ryan, Rivera-Hernandez, Melody, Kenniston, Jon A, Papaioannou, Nikolaos, Cosic, Janja, Kopacz, Kris, Salmon, Gary, Beauchemin, Chantal, Juethner, Salomé, Yeung, Dave

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Sculpting the Proteome with AAA+ Proteases and Disassembly Machines von Sauer, Robert T., Bolon, Daniel N., Burton, Briana M., Burton, Randall E., Flynn, Julia M., Grant, Robert A., Hersch, Greg L., Joshi, Shilpa A., Kenniston, Jon A., Levchenko, Igor, Neher, Saskia B., Oakes, Elizabeth S.C., Siddiqui, Samia M., Wah, David A., Baker, Tania A.

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A phase 1 study investigating DX-2930 in healthy subjects von Chyung, Yung, MD, Vince, Bradley, DO, Iarrobino, Ryan, BA, Sexton, Dan, PhD, Kenniston, Jon, PhD, Faucette, Ryan, BS, TenHoor, Chris, PharmD, PhD, Stolz, Leslie E., PhD, Stevens, Chris, MD, Biedenkapp, Joseph, PhD, Adelman, Burt, MD

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Partitioning between Unfolding and Release of Native Domains during ClpXP Degradation Determines Substrate Selectivity and Partial Processing von Kenniston, Jon A., Baker, Tania A., Sauer, Robert T.

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Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody von Kenniston, Jon A., Taylor, Brandy M., Conley, Gregory P., Cosic, Janja, Kopacz, Kris J., Lindberg, Allison P., Comeau, Stephen R., Atkins, Kateri, Bullen, Jameson, TenHoor, Christopher, Adelman, Burt A., Sexton, Daniel J., Edwards, Thomas E., Nixon, Andrew E.

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Single-molecule denaturation and degradation of proteins by the AAA+ ClpXP protease von Shin, Yongdae, Davis, Joseph H, Brau, Ricardo R, Martin, Andreas, Kenniston, Jon A, Baker, Tania A, Sauer, Robert T, Lang, Matthew J

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A homogeneous fluorescence anisotropy assay for measuring transglutaminase 2 activity von Kenniston, Jon A., Conley, Gregory P., Sexton, Daniel J., Nixon, Andrew E.

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Anti-sFlt-1 Therapy Preserves Lung Alveolar and Vascular Growth in Antenatal Models of Bronchopulmonary Dysplasia von Wallace, Bradley, Peisl, Amelie, Seedorf, Gregory, Nowlin, Taylor, Kim, Christina, Bosco, Jennifer, Kenniston, Jon, Keefe, Dennis, Abman, Steven H

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Effects of local protein stability and the geometric position of the substrate degradation tag on the efficiency of ClpXP denaturation and degradation von Kenniston, Jon A, Burton, Randall E, Siddiqui, Samia M, Baker, Tania A, Sauer, Robert T

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Signaling degradation von Kenniston, Jon A, Sauer, Robert T

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A phase 1/2 safety and efficacy study of TAK‐754 gene therapy: The challenge of achieving durable factor VIII expression in haemophilia A clinical trials von Chapin, John, Álvarez Román, Maria Teresa, Ayash‐Rashkovsky, Mila, Diogo, Dorothee, Kenniston, Jon, Lopez‐Jaime, Francisco‐Jose, Maggiore, Caterina, Mingot‐Castellano, María‐Eva, Rajavel, Kavitha, Rauch, Antoine, Susen, Sophie, Grotthuss, Marcin, Wagoner, Matt, Wang, Qin

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Stimulated Platelets but Not Endothelium Generate Thrombin Via a Factor XIIa-Dependent Mechanism Requiring Phosphatidylserine Exposure von Bendapudi, Pavan K., Deceunynck, Karen, Koseoglu, Secil, Bekendam, Roelof Hendrik, Mason, Shauna D, Kenniston, Jon, Flaumenhaft, Robert C.

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Effect of Lanadelumab on Coagulation Parameters in Patients With Hereditary Angioedema: Findings From The Phase 3 HELP Study von Schmaier, Alvin H., Bauer, Kenneth A., Cicardi, Marco, Hebert, Jacques, Johnston, Douglas T., Busse, Paula J., Paes, Kim, Sexton, Daniel J., Kenniston, Jon, Nurse, Christina, Zaragoza, Rafael H.

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A Biomarker Assay For The Detection Of Contact System Activation von Faucette, Ryan R, Cicardi, Marco, Suffritti, Chiara, Kenniston, Jon A, Sexton, Daniel J, Adelman, Burt

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