Challenges to the broad application of allogeneic natural killer cell immunotherapy of cancer von Kennedy, Philippa R, Felices, Martin, Miller, Jeffrey S

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Maternal uterine NK cell-activating receptor KIR2DS1 enhances placentation von Xiong, Shiqiu, Sharkey, Andrew M, Kennedy, Philippa R, Gardner, Lucy, Farrell, Lydia E, Chazara, Olympe, Bauer, Julien, Hiby, Susan E, Colucci, Francesco, Moffett, Ashley

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Activating KIR2DS4 Is Expressed by Uterine NK Cells and Contributes to Successful Pregnancy von Kennedy, Philippa R, Chazara, Olympe, Gardner, Lucy, Ivarsson, Martin A, Farrell, Lydia E, Xiong, Shiqiu, Hiby, Susan E, Colucci, Francesco, Sharkey, Andrew M, Moffett, Ashley

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The Size of Activating and Inhibitory Killer Ig-like Receptor Nanoclusters Is Controlled by the Transmembrane Sequence and Affects Signaling von Oszmiana, Anna, Williamson, David J., Cordoba, Shaun-Paul, Morgan, David J., Kennedy, Philippa R., Stacey, Kevin, Davis, Daniel M.

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The effect of pregnancy on the uterine NK cell KIR repertoire von Male, Victoria, Sharkey, Andrew, Masters, Leanne, Kennedy, Philippa R., Farrell, Lydia E., Moffett, Ashley

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Tissue-Specific Education of Decidual NK Cells von Sharkey, Andrew M, Xiong, Shiqiu, Kennedy, Philippa R, Gardner, Lucy, Farrell, Lydia E, Chazara, Olympe, Ivarsson, Martin A, Hiby, Susan E, Colucci, Francesco, Moffett, Ashley

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Diversity of peripheral blood human NK cells identified by single-cell RNA sequencing von Smith, Samantha L., Kennedy, Philippa R., Stacey, Kevin B., Worboys, Jonathan D., Yarwood, Annie, Seo, Seungmae, Solloa, Everardo Hegewisch, Mistretta, Brandon, Chatterjee, Sujash S., Gunaratne, Preethi, Allette, Kimaada, Wang, Ying-Chih, Smith, Melissa Laird, Sebra, Robert, Mace, Emily M., Horowitz, Amir, Thomson, Wendy, Martin, Paul, Eyre, Steve, Davis, Daniel M.

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A tri-specific killer engager against mesothelin targets NK cells towards lung cancer von Kennedy, Philippa R, Vallera, Daniel A, Ettestad, Brianna, Hallstrom, Caroline, Kodal, Behiye, Todhunter, Deborah A, Bendzick, Laura, Hinderlie, Peter, Walker, Joshua T, Pulkrabek, Brittany, Pastan, Ira, Kratzke, Robert A, Fujioka, Naomi, Miller, Jeffrey S, Felices, Martin

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The central role of the cytoskeleton in mechanisms and functions of the NK cell immune synapse von Lagrue, Kathryn, Carisey, Alex, Oszmiana, Anna, Kennedy, Philippa R., Williamson, David J., Cartwright, Adam, Barthen, Charlotte, Davis, Daniel M.

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Ablation of SYK Kinase from Expanded Primary Human NK Cells via CRISPR/Cas9 Enhances Cytotoxicity and Cytokine Production von Dahlvang, James D, Dick, Jenna K, Sangala, Jules A, Kennedy, Philippa R, Pomeroy, Emily J, Snyder, Kristin M, Moushon, Juliette M, Thefaine, Claire E, Wu, Jianming, Hamilton, Sara E, Felices, Martin, Miller, Jeffrey S, Walcheck, Bruce, Webber, Beau R, Moriarity, Branden S, Hart, Geoffrey T

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HLA-B and HLA-C Differ in Their Nanoscale Organization at Cell Surfaces von Kennedy, Philippa R, Barthen, Charlotte, Williamson, David J, Davis, Daniel M

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Genetic diversity affects the nanoscale membrane organization and signaling of natural killer cell receptors von Kennedy, Philippa R, Barthen, Charlotte, Williamson, David J, Pitkeathly, William T E, Hazime, Khodor S, Cumming, Joshua, Stacey, Kevin B, Hilton, Hugo G, Carrington, Mary, Parham, Peter, Davis, Daniel M

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NK Cells Augment Oncolytic Adenovirus Cytotoxicity in Ovarian Cancer von Leung, Elaine Y.L., Ennis, Darren P., Kennedy, Philippa R., Hansell, Christopher, Dowson, Suzanne, Farquharson, Malcolm, Spiliopoulou, Pavlina, Nautiyal, Jaya, McNamara, Sophie, Carlin, Leo M., Fisher, Kerry, Davis, Daniel M., Graham, Gerard, McNeish, Iain A.

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Metabolic programs drive function of therapeutic NK cells in hypoxic tumor environments von Kennedy, Philippa R, Arvindam, Upasana Sunil, Phung, Shee Kwan, Ettestad, Brianna, Feng, Xueyang, Li, Yunmin, Kile, Quinlan M, Hinderlie, Peter, Khaw, Melissa, Huang, Rih-Sheng, Kaufman, Marissa, Puchalska, Patrycja, Russell, Amanda, Butler, Jonah, Abbott, Lucas, McClure, Paul, Luo, Xianghua, Lu, Quynhanh T, Blazar, Bruce R, Crawford, Peter A, Lim, James, Miller, Jeffrey S, Felices, Martin

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638 Hypoxia reprograms natural killer cells and impairs their therapeutic potential von Kennedy, Philippa, Arvindam, Upasana Sunil, Ettestad, Brianna, Phung, Shee Kwan, Kile, Quinlan, Hinderlie, Peter, Li, Yunmin, Lim, James, Miller, Jeffrey, Felices, Martin

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1180 Maximizing NK cell immunotherapy in prostate cancer via TriKEs von Phung, Shee Kwan, Zorko, Nicholas, Shackelford, Madison, Bozicevich, Asha, Bendzick, Laura, Selleck, Carly, Soignier, Yvette, Nelson, Trygve, Walker, Joshua, Hinderlie, Peter, Kennedy, Philippa R, Miller, Jeffrey S, Felices, Martin

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365 Oxygen levels found in bone marrow (5%) provide an optimal niche for the differentiation of induced-pluripotent stem cell-derived NK cells for the treatment of AML von Kennedy, Philippa R, Kile, Quinlan M, Waller, Rhett L, Bendzick, Laura, Selleck, Carly, Hinderlie, Peter, Kaufman, Marissa, Kodal, Behiye, Valamehr, Bahram, Miller, Jeffrey S, Felices, Martin

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Acoustic noise reduces foraging success in two sympatric fish species via different mechanisms von Voellmy, Irene K., Purser, Julia, Flynn, Douglas, Kennedy, Philippa, Simpson, Stephen D., Radford, Andrew N.

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Hypoxia profoundly alters Natural Killer cell phenotype and function: implications for immunotherapy within the solid tumor microenvironment von Arvindam, Upasana Sunil, Kennedy, Philippa, Ettestad, Brianna, Phung, Shee Kwan, Hinderlie, Peter, Lim, James, Miller, Jeffrey S, Felices, Martin

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Ablation of SYK kinase from expanded primary human Natural Killer cells via CRISPR/Cas9 enhances cytotoxicity and cytokine production von Dahlvang, James D., Dick, Jenna K., Sangala, Jules A., Kennedy, Philippa R., Pomeroy, Emily J., Snyder, Kristin M., Moushon, Juliette M., Thefaine, Claire E., Wu, Jianming, Hamilton, Sara E., Felices, Martin, Miller, Jeffrey S., Walcheck, Bruce, Webber, Beau R., Moriarity, Branden S., Hart, Geoffrey T.

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