Genetic predisposition to MDS: clinical features and clonal evolution von Kennedy, Alyssa L., Shimamura, Akiko

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Dissecting ELANE neutropenia pathogenicity by human HSC gene editing von Rao, Shuquan, Yao, Yao, Soares de Brito, Josias, Yao, Qiuming, Shen, Anne H., Watkinson, Ruth E., Kennedy, Alyssa L., Coyne, Steven, Ren, Chunyan, Zeng, Jing, Serbin, Anna Victoria, Studer, Sabine, Ballotti, Kaitlyn, Harris, Chad E., Luk, Kevin, Stevens, Christian S., Armant, Myriam, Pinello, Luca, Wolfe, Scot A., Chiarle, Roberto, Shimamura, Akiko, Lee, Benhur, Newburger, Peter E., Bauer, Daniel E.

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Activation of the PIK3CA/AKT Pathway Suppresses Senescence Induced by an Activated RAS Oncogene to Promote Tumorigenesis von Kennedy, Alyssa L., Morton, Jennifer P., Manoharan, Indrani, Nelson, David M., Jamieson, Nigel B., Pawlikowski, Jeff S., McBryan, Tony, Doyle, Brendan, McKay, Colin, Oien, Karin A., Enders, Greg H., Zhang, Rugang, Sansom, Owen J., Adams, Peter D.

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Induction of remission after donor lymphocyte infusion following allogeneic transplant in a case of pediatric primary myelofibrosis von Li, Amy, Sze, Sei‐Gyung K., Kapadia, Malika, Lehmann, Leslie, Bledsoe, Jacob R., Kennedy, Alyssa L.

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Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma von Kennedy, Alyssa L, Vallurupalli, Mounica, Chen, Liying, Crompton, Brian, Cowley, Glenn, Vazquez, Francisca, Weir, Barbara A, Tsherniak, Aviad, Parasuraman, Sudha, Kim, Sunkyu, Alexe, Gabriela, Stegmaier, Kimberly

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The MYCN 5′ UTR as a therapeutic target in neuroblastoma von Volegova, Marina P., Brown, Lauren E., Banerjee, Ushashi, Dries, Ruben, Sharma, Bandana, Kennedy, Alyssa, Porco, John A., George, Rani E.

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Downregulation of Wnt Signaling Is a Trigger for Formation of Facultative Heterochromatin and Onset of Cell Senescence in Primary Human Cells von Ye, Xiaofen, Zerlanko, Brad, Kennedy, Alyssa, Banumathy, Gowrishankar, Zhang, Rugang, Adams, Peter D.

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Senescent mouse cells fail to overtly regulate the HIRA histone chaperone and do not form robust Senescence Associated Heterochromatin Foci von Kennedy, Alyssa L, McBryan, Tony, Enders, Greg H, Johnson, F Brad, Zhang, Rugang, Adams, Peter D

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Pediatric CNS-isolated hemophagocytic lymphohistiocytosis von Benson, Leslie A, Li, Hojun, Henderson, Lauren A, Solomon, Isaac H, Soldatos, Ariane, Murphy, Jennifer, Bielekova, Bibiana, Kennedy, Alyssa L, Rivkin, Michael J, Davies, Kimberly J, Hsu, Amy P, Holland, Steven M, Gahl, William A, Sundel, Robert P, Lehmann, Leslie E, Lee, Michelle A, Alexandrescu, Sanda, Degar, Barbara A, Duncan, Christine N, Gorman, Mark P

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The frequent and clinically benign anomalies of chromosomes 7 and 20 in Shwachman-diamond syndrome may be subject to further clonal variations von Khan, Abdul Waheed, Kennedy, Alyssa, Furutani, Elissa, Myers, Kasiani, Frattini, Annalisa, Acquati, Francesco, Roccia, Pamela, Micheloni, Giovanni, Minelli, Antonella, Porta, Giovanni, Cipolli, Marco, Cesaro, Simone, Danesino, Cesare, Pasquali, Francesco, Shimamura, Akiko, Valli, Roberto

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Ras, PI3K/Akt and senescence: Paradoxes provide clues for pancreatic cancer therapy von Kennedy, Alyssa L., Adams, Peter D., Morton, Jennifer P.

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Central nervous system–restricted familial hemophagocytic lymphohistiocytosis responds to hematopoietic cell transplantation von Li, Hojun, Benson, Leslie A., Henderson, Lauren A., Solomon, Isaac H., Kennedy, Alyssa L., Soldatos, Ariane, Bielekova, Bibiana, Murphy, Jennifer, Davies, Kimberly J., Lehmann, Leslie E., Lee, Michelle A., Alexandrescu, Sanda, Degar, Barbara A., Gorman, Mark P., Duncan, Christine N.

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Targeting EZH2 for the treatment of hepatosplenic T-cell lymphoma von Pikman, Yana, Conway, Amy Saur, Robichaud, Amanda L., Kitara, Samuel, Church, Alanna J., Kennedy, Alyssa L., Silverman, Lewis B., Billett, Amy L., Weinstock, David M., Harris, Marian H., Stegmaier, Kimberly

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Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome von Kennedy, Alyssa L, Myers, Kasiani C, Bowman, James, Gibson, Christopher J, Camarda, Nicholas D, Furutani, Elissa, Boettcher, Steffen

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Homozygous loss of menin is well tolerated in liver, a tissue not affected in MEN1 von Scacheri, Peter C, Crabtree, Judy S, Kennedy, Alyssa L, Swain, Gary P, Ward, Jerrold M, Marx, Stephen J, Spiegel, Allen M, Collins, Francis S

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869. A Qualitative Review of Social Barriers Impeding Retention in HIV Care at a Ryan White Clinic von Florakis, Eleni, Johanna, Smith, Kennedy, Alyssa, Spacek, Lisa A

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Hierarchy of Supramolecular Synthons: Persistent Hydrogen Bonds Between Carboxylates and Weakly Acidic Hydroxyl Moieties in Cocrystals of Zwitterions von Kavuru, Padmini, Aboarayes, Dalia, Arora, Kapildev K, Clarke, Heather D, Kennedy, Alyssa, Marshall, Lissette, Ong, Tien Teng, Perman, Jason, Pujari, Twarita, Wojtas, Łukasz, Zaworotko, Michael J

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Large Genomic Deletions in Shwachman-Diamond Syndrome von McReynolds, Lisa J., Jones, Kristine, Teshome, Kedest, Kennedy, Alyssa, Shimamura, Akiko, Giri, Neelam, Alter, Blanche P., Savage, Sharon A.

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Targeting a Putative Intronic Splicing Silencer Salvages Expression from the Recurrent SBDS C.258+2T>C Mutant Allele in Shwachman-Diamond Syndrome Patient Cells and Mouse Model von Peters, Michael J., Deck, Anna, Hu, April, Fujiwara, Yuko, Kim, Jinkuk, Soucy, Aubrie, Zhang, Kevin, Kenny, Julianna, Lin, Linda Y., Kennedy, Alyssa L., Bowers, Caitlin, Harris, Chad E., Zhang, Chi Yuan, Ponnienselvan, Karthik, Liu, Pengpeng, Luk, Kevin, Seruggia, Davide, Lindsley, R. Coleman, Manis, John P., Brendel, Christian, Wolfe, Scot A., Orkin, Stuart H., Yu, Timothy, Shimamura, Akiko, Bauer, Daniel E.

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Pancreatic insulinomas in multiple endocrine neoplasia, type I knockout mice can develop in the absence of chromosome instability or microsatellite instability von SCACHERI, Peter C, KENNEDY, Alyssa L, CHIN, Koei, MILLER, Meghan T, HODGSON, J. Graeme, GRAY, Joe W, MARX, Stephen J, SPIEGEL, Allen M, COLLINS, Francis S

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