A Structure-Based Approach to Ligand Discovery for 2C-Methyl-d-erythritol-2,4-cyclodiphosphate Synthase: A Target for Antimicrobial Therapy von Ramsden, Nicola L, Buetow, Lori, Dawson, Alice, Kemp, Lauris A, Ulaganathan, Venkatsubramanian, Brenk, Ruth, Klebe, Gerhard, Hunter, William N

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A Structure-Based Approach to Ligand Discovery for 2 C -Methyl- d -erythritol-2,4-cyclodiphosphate Synthase: A Target for Antimicrobial Therapy von Ramsden, Nicola L., Buetow, Lori, Dawson, Alice, Kemp, Lauris A., Ulaganathan, Venkatsubramanian, Brenk, Ruth, Klebe, Gerhard, Hunter, William N.

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A Structure-Based Approach to Ligand Discovery for 2C-Methyl- d -erythritol-2,4-cyclodiphosphate Synthase: A Target for Antimicrobial Therapy aNB von Ramsden, Nicola L, Buetow, Lori, Dawson, Alice, Kemp, Lauris A, Ulaganathan, Venkatsubramanian, Brenk, Ruth, Klebe, Gerhard, Hunter, William N

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Biosynthesis of Isoprenoids: Crystal Structure of 4-Diphosphocytidyl-2C-Methyl-D-Erythritol Kinase von Miallau, Linda, Alphey, Magnus S., Kemp, Lauris E., Leonard, Gordon A., McSweeney, Sean M., Hecht, Stefan, Bacher, Adelbert, Eisenreich, Wolfgang, Rohdich, Felix, Hunter, William N.

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Structure of 2C-Methyl-D-Erythritol 2,4-Cyclodiphosphate Synthase: An Essential Enzyme for Isoprenoid Biosynthesis and Target for Antimicrobial Drug Development von Kemp, Lauris E., Bond, Charles S., Hunter, William N.

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The identification of isoprenoids that bind in the intersubunit cavity of Escherichia coli 2C-methyl-d-erythritol-2,4-cyclodiphosphate synthase by complementary biophysical methods von Kemp, Lauris E., Alphey, Magnus S., Bond, Charles S., Ferguson, Michael A. J., Hecht, Stefan, Bacher, Adelbert, Eisenreich, Wolfgang, Rohdich, Felix, Hunter, William N.

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Structure of a tetragonal crystal form of Escherichia coli 2-C-methyl-d-erythritol 4-phosphate cytidylyltransferase von Kemp, Lauris E., Bond, Charles S., Hunter, William N.

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Crystallization and preliminary X-ray diffraction studies of recombinant Escherichia coli 4-­diphosphocytidyl-2-C-methyl-d-erythritol synthetase von Kemp, Lauris E., Bond, Charles S., Hunter, William N.

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A double mutation of Escherichia coli 2C-methyl-d-erythritol-2,4-cyclodiphosphate synthase disrupts six hydrogen bonds with, yet fails to prevent binding of, an isoprenoid diphosph... von Sgraja, Tanja, Kemp, Lauris E., Ramsden, Nicola, Hunter, William N.

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The organization of divalent cations in the active site of cadmium Escherichia coli fructose-1,6-bisphosphate aldolase von Hall, David R., Kemp, Lauris E., Leonard, Gordon A., Marshall, Karen, Berry, Alan, Hunter, William N.

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The identification of isoprenoids that bind in the intersubunit cavity of Escherichia coli 2 C -methyl- D -erythritol-2,4-cyclodiphosphate synthase by complementary biophysical met... von Kemp, Lauris E., Alphey, Magnus S., Bond, Charles S., Ferguson, Michael A. J., Hecht, Stefan, Bacher, Adelbert, Eisenreich, Wolfgang, Rohdich, Felix, Hunter, William N.

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A double mutation of Escherichia coli 2 C -methyl- D -erythritol-2,4-cyclodiphosphate synthase disrupts six hydrogen bonds with, yet fails to prevent binding of, an isoprenoid diph... von Sgraja, Tanja, Kemp, Lauris E., Ramsden, Nicola, Hunter, William N.

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A double mutation of Escherichia coli2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase disrupts six hydrogen bonds with, yet fails to prevent binding of, an isoprenoid diphospha... von Sgraja, Tanja, Kemp, Lauris E, Ramsden, Nicola, Hunter, William N

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