Novel antibody–antibiotic conjugate eliminates intracellular S. aureus von Lehar, Sophie M., Pillow, Thomas, Xu, Min, Staben, Leanna, Kajihara, Kimberly K., Vandlen, Richard, DePalatis, Laura, Raab, Helga, Hazenbos, Wouter L., Hiroshi Morisaki, J., Kim, Janice, Park, Summer, Darwish, Martine, Lee, Byoung-Chul, Hernandez, Hilda, Loyet, Kelly M., Lupardus, Patrick, Fong, Rina, Yan, Donghong, Chalouni, Cecile, Luis, Elizabeth, Khalfin, Yana, Plise, Emile, Cheong, Jonathan, Lyssikatos, Joseph P., Strandh, Magnus, Koefoed, Klaus, Andersen, Peter S., Flygare, John A., Wah Tan, Man, Brown, Eric J., Mariathasan, Sanjeev

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Identification and characterization of an octameric PEG-protein conjugate system for intravitreal long-acting delivery to the back of the eye von Shatz, Whitney, Hass, Philip E, Peer, Nikhil, Paluch, Maciej T, Blanchette, Craig, Han, Guanghui, Sandoval, Wendy, Morando, Ashley, Loyet, Kelly M, Bantseev, Vladimir, Booler, Helen, Crowell, Susan, Kamath, Amrita, Scheer, Justin M, Kelley, Robert F

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Reconstitution of the alternative pathway of the complement system enables rapid delineation of the mechanism of action of novel inhibitors von Goodrich, Andrew C., LeClair, Norbert P., Shillova, Nita, Morton, William D., Wittwer, Arthur J., Loyet, Kelly M., Hannoush, Rami N.

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Pre-clinical and translational pharmacology of a human interleukin-22 IgG fusion protein for potential treatment of infectious or inflammatory diseases von Stefanich, Eric G., Rae, Julie, Sukumaran, Siddharth, Lutman, Jeff, Lekkerkerker, Annemarie, Ouyang, Wenjun, Wang, Xiaoting, Lee, Donna, Danilenko, Dimitry M., Diehl, Lauri, Loyet, Kelly M., Herman, Ann

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Dramatic activation of an antibody by a single amino acid change in framework von Liang, Wei-Ching, Yin, Jianping, Lupardus, Patrick, Zhang, Jianhuan, Loyet, Kelly M., Sudhamsu, Jawahar, Wu, Yan

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Bivalent antibody pliers inhibit β-tryptase by an allosteric mechanism dependent on the IgG hinge von Maun, Henry R., Vij, Rajesh, Walters, Benjamin T., Morando, Ashley, Jackman, Janet K., Wu, Ping, Estevez, Alberto, Chen, Xiaocheng, Franke, Yvonne, Lipari, Michael T., Dennis, Mark S., Kirchhofer, Daniel, Ciferri, Claudio, Loyet, Kelly M., Yi, Tangsheng, Eigenbrot, Charles, Lazarus, Robert A., Koerber, James T.

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Potent Killing of Pseudomonas aeruginosa by an Antibody-Antibiotic Conjugate von Kajihara, Kimberly K, Pantua, Homer, Hernandez-Barry, Hilda, Hazen, Meredith, Deshmukh, Kiran, Chiang, Nancy, Ohri, Rachana, Castellanos, Erick R, Martin, Lynn, Matsumoto, Marissa L, Payandeh, Jian, Storek, Kelly M, Schneider, Kellen, Smith, Peter A, Koehler, Michael F T, Tsai, Siao Ping, Vandlen, Richard, Loyet, Kelly M, Nakamura, Gerald, Pillow, Thomas, Seshasayee, Dhaya, Kapadia, Sharookh B, Hazenbos, Wouter L W

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Retinal and Lens Degeneration in New Zealand White Rabbits Administered Intravitreal TSG-6 Link Domain-Rabbit FAb Fusion Proteins von Laing, Steven T., Tassew, Nardos, Tesar, Devin, Wang, Yue, Crowell, Susan R., Gray, Julia, Kwong, Mandy, Loyet, Kelly M., Andaya, Roxanne, Kusi, Aija, Kelley, Robert F.

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A homogeneous high-DAR antibody-drug conjugate platform combining THIOMAB antibodies and XTEN polypeptides von Zacharias, Neelie, Podust, Vladimir N, Kajihara, Kimberly K, Leipold, Douglas, Del Rosario, Geoffrey, Thayer, Desiree, Dong, Emily, Paluch, Maciej, Fischer, David, Zheng, Kai, Lei, Corinna, He, Jintang, Ng, Carl, Su, Dian, Liu, Luna, Masih, Shabkhaiz, Sawyer, William, Tinianow, Jeff, Marik, Jan, Yip, Victor, Li, Guangmin, Chuh, Josefa, Morisaki, J Hiroshi, Park, Summer, Zheng, Bing, Hernandez-Barry, Hilda, Loyet, Kelly M, Xu, Min, Kozak, Katherine R, Phillips, Gail Lewis, Shen, Ben-Quan, Wu, Cong, Xu, Keyang, Yu, Shang-Fan, Kamath, Amrita, Rowntree, Rebecca K, Reilly, Dorothea, Pillow, Thomas, Polson, Andrew, Schellenberger, Volker, Hazenbos, Wouter L W, Sadowsky, Jack

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Hyaluronic Acid–Antibody Fragment Bioconjugates for Extended Ocular Pharmacokinetics von Famili, Amin, Crowell, Susan R, Loyet, Kelly M, Mandikian, Danielle, Boswell, C. Andrew, Cain, David, Chan, Joyce, Comps-Agrar, Laetitia, Kamath, Amrita, Rajagopal, Karthikan

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Complement Inhibition in Cynomolgus Monkeys by Anti–Factor D Antigen-Binding Fragment for the Treatment of an Advanced Form of Dry Age-Related Macular Degeneration von Loyet, Kelly M., Good, Jeremy, Davancaze, Teresa, Sturgeon, Lizette, Wang, Xiangdan, Yang, Jihong, Le, Kha N., Wong, Maureen, Hass, Philip E., Campagne, Menno van Lookeren, Haughney, Peter C., Morimoto, Alyssa, Damico-Beyer, Lisa A., DeForge, Laura E.

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Development of an ultra-sensitive human IL-33 biomarker assay for age-related macular degeneration and asthma drug development von Mai, Elaine, Chan, Joyce, Goon, Levina, Ego, Braeden K, Bevers, Jack, Wong, Tiffany, Wong, Manda, Corpuz, Racquel, Xi, Hongkang, Wu, Jia, Schneider, Kellen, Seshasayee, Dhaya, Grimbaldeston, Michele, Nakamura, Gerald, Indjeian, Vahan B, van Lookeren Campagne, Menno, Loyet, Kelly M, Comps-Agrar, Laetitia

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A Coreceptor Interaction between the CD28 and TNF Receptor Family Members B and T Lymphocyte Attenuator and Herpesvirus Entry Mediator von Gonzalez, Lino C., Loyet, Kelly M., Calemine-Fenaux, Jill, Chauhan, Vandana, Wranik, Bernd, Ouyang, Wenjun, Eaton, Dan L., Scheller, Richard H.

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Fab-Nanolipoprotein Conjugate Causes Vitreous Opacity and Cataracts Following a Single Intravitreal Administration in New Zealand White Rabbits von Tassew, Nardos G., Laing, Steven T., Shatz, Whitney, Crowell, Susan R., Loyet, Kelly M., Schuetz, Chris, Blanchette, Craig

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Influence of Charge, Hydrophobicity, and Size on Vitreous Pharmacokinetics of Large Molecules von Crowell, Susan R, Wang, Kathryn, Famili, Amin, Shatz, Whitney, Loyet, Kelly M, Chang, Vincent, Liu, Yanqiu, Prabhu, Saileta, Kamath, Amrita V, Kelley, Robert F

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Activation of the alternative complement pathway in vitreous is controlled by genetics in age-related macular degeneration von Loyet, Kelly M, Deforge, Laura E, Katschke, Jr, Kenneth J, Diehl, Lauri, Graham, Robert R, Pao, Lily, Sturgeon, Lizette, Lewin-Koh, Sock-Cheng, Hollyfield, Joe G, van Lookeren Campagne, Menno

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A Mechanistic Pharmacokinetic/Pharmacodynamic Model of Factor D Inhibition in Cynomolgus Monkeys by Lampalizumab for the Treatment of Geographic Atrophy von Le, Kha N., Gibiansky, Leonid, Good, Jeremy, Davancaze, Teresa, van Lookeren Campagne, Menno, Loyet, Kelly M., Morimoto, Alyssa, Jin, Jin, Damico-Beyer, Lisa A., Hanley, William D.

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Pharmacokinetics of Humanized Monoclonal Anti-Tumor Necrosis Factor-α Antibody and Its Neonatal Fc Receptor Variants in Mice and Cynomolgus Monkeys von RONG DENG, LOYET, Kelly M, LIEN, Samantha, LYER, Suhasini, DEFORGE, Laura E, THEIL, Frank-Peter, LOWMAN, Henry B, FIELDER, Paul J, PRABHU, Saileta

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Modeling approach to investigate the effect of neonatal Fc receptor binding affinity and anti-therapeutic antibody on the pharmacokinetic of humanized monoclonal anti-tumor necrosi... von Ng, Chee M., Loyet, Kelly M., Iyer, Suhasini, Fielder, Paul J., Deng, Rong

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Attenuating lymphocyte activity: the crystal structure of the BTLA-HVEM complex von Compaan, Deanne M, Gonzalez, Lino C, Tom, Irene, Loyet, Kelly M, Eaton, Dan, Hymowitz, Sarah G

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