Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature von Haberman, Yael, Tickle, Timothy L, Dexheimer, Phillip J, Kim, Mi-Ok, Tang, Dora, Karns, Rebekah, Baldassano, Robert N, Noe, Joshua D, Rosh, Joel, Markowitz, James, Heyman, Melvin B, Griffiths, Anne M, Crandall, Wallace V, Mack, David R, Baker, Susan S, Huttenhower, Curtis, Keljo, David J, Hyams, Jeffrey S, Kugathasan, Subra, Walters, Thomas D, Aronow, Bruce, Xavier, Ramnik J, Gevers, Dirk, Denson, Lee A

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Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course von Schirmer, Melanie, Denson, Lee, Vlamakis, Hera, Franzosa, Eric A., Thomas, Sonia, Gotman, Nathan M., Rufo, Paul, Baker, Susan S., Sauer, Cary, Markowitz, James, Pfefferkorn, Marian, Oliva-Hemker, Maria, Rosh, Joel, Otley, Anthony, Boyle, Brendan, Mack, David, Baldassano, Robert, Keljo, David, LeLeiko, Neal, Heyman, Melvin, Griffiths, Anne, Patel, Ashish S., Noe, Joshua, Kugathasan, Subra, Walters, Thomas, Huttenhower, Curtis, Hyams, Jeffrey, Xavier, Ramnik J.

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Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study von Hyams, Jeffrey S, Davis Thomas, Sonia, Gotman, Nathan, Haberman, Yael, Karns, Rebekah, Schirmer, Melanie, Mo, Angela, Mack, David R, Boyle, Brendan, Griffiths, Anne M, LeLeiko, Neal S, Sauer, Cary G, Keljo, David J, Markowitz, James, Baker, Susan S, Rosh, Joel, Baldassano, Robert N, Patel, Ashish, Pfefferkorn, Marian, Otley, Anthony, Heyman, Melvin, Noe, Joshua, Oliva-Hemker, Maria, Rufo, Paul A, Strople, Jennifer, Ziring, David, Guthery, Stephen L, Sudel, Boris, Benkov, Keith, Wali, Prateek, Moulton, Dedrick, Evans, Jonathan, Kappelman, Michael D, Marquis, M Alison, Sylvester, Francisco A, Collins, Margaret H, Venkateswaran, Suresh, Dubinsky, Marla, Tangpricha, Vin, Spada, Krista L, Saul, Bradley, Wang, Jessie, Serrano, Jose, Hommel, Kevin, Marigorta, Urko M, Gibson, Greg, Xavier, Ramnik J, Kugathasan, Subra, Walters, Thomas, Denson, Lee A

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Biologics Delay Progression of Crohn’s Disease, but Not Early Surgery, in Children von Kerur, Basavaraj, Machan, Jason T., Shapiro, Jason M., Cerezo, Carolina S., Markowitz, James, Mack, David R., Griffiths, Anne M., Otley, Anthony R., Pfefferkorn, Marian D., Rosh, Joel R., Keljo, David J., Boyle, Brendan, Oliva-Hemker, Maria, Kay, Marsha H., Saeed, Shehzad A., Grossman, Andrew B., Sudel, Boris, Kappelman, Michael D., Schaefer, Marc, Tomer, Gitit, Bousvaros, Athos, Lerer, Trudy, Hyams, Jeffrey S., LeLeiko, Neal S.

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2015 AAP Murray Davidson Award von Keljo, David J.

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Severe Pediatric Ulcerative Colitis: A Prospective Multicenter Study of Outcomes and Predictors of Response von Turner, Dan, Mack, David, Leleiko, Neal, Walters, Thomas D, Uusoue, Krista, Leach, Steven T, Day, Andrew S, Crandall, Wallace, Silverberg, Mark S, Markowitz, James, Otley, Anthony R, Keljo, David, Mamula, Petar, Kugathasan, Subra, Hyams, Jeffrey, Griffiths, Anne M

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Long ncRNA Landscape in the Ileum of Treatment-Naive Early-Onset Crohn Disease von Haberman, Yael, BenShoshan, Marina, Di Segni, Ayelet, Dexheimer, Phillip J, Braun, Tzipi, Weiss, Batia, Walters, Thomas D, Baldassano, Robert N, Noe, Joshua D, Markowitz, James, Rosh, Joel, Heyman, Melvin B, Griffiths, Anne M, Crandall, Wallace V, Mack, David R, Baker, Susan S, Kellermayer, Richard, Patel, Ashish, Otley, Anthony, Steiner, Steven J, Gulati, Ajay S, Guthery, Stephen L, LeLeiko, Neal, Moulton, Dedrick, Kirschner, Barbara S, Snapper, Scott, Avivi, Camila, Barshack, Iris, Oliva-Hemker, Maria, Cohen, Stanley A, Keljo, David J, Ziring, David, Anikster, Yair, Aronow, Bruce, Hyams, Jeffrey S, Kugathasan, Subra, Denson, Lee A

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Randomized Efficacy Trial of Two Psychotherapies for Depression in Youth With Inflammatory Bowel Disease von Szigethy, Eva, MD, PhD, Bujoreanu, Simona I., PhD, Youk, Ada O., PhD, Weisz, John, PhD, Benhayon, David, MD, PhD, Fairclough, Diane, DrPh, Ducharme, Peter, LICSW, Gonzalez-Heydrich, Joseph, MD, Keljo, David, MD, Srinath, Arvind, MD, Bousvaros, Athos, MD, Kirshner, Margaret, BA, Newara, Melissa, MS, Kupfer, David, MD, DeMaso, David R., MD

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Appraisal of the Pediatric Ulcerative Colitis Activity Index (PUCAI) von Turner, Dan, Hyams, Jeffrey, Markowitz, James, Lerer, Trudy, Mack, David R., Evans, Jonathan, Pfefferkorn, Marian, Rosh, Joel, Kay, Marsha, Crandall, Wallace, Keljo, David, Otley, Anthony R., Kugathasan, Subra, Carvalho, Ryan, Oliva-Hemker, Maria, Langton, Christine, Mamula, Petar, Bousvaros, Athos, LeLeiko, Neal, Griffiths, Anne M.

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Clinical Presentation and Five-Year Therapeutic Management of Very Early-Onset Inflammatory Bowel Disease in a Large North American Cohort von Oliva-Hemker, Maria, MD, Hutfless, Susan, PhD, Al Kazzi, Elie S., MD, MPH, Lerer, Trudy, MS, Mack, David, MD, LeLeiko, Neal, MD, PhD, Griffiths, Anne, MD, Cabrera, Jose, MD, Otley, Anthony, MD, Rick, James, MD, Bousvaros, Athos, MD, Rosh, Joel, MD, Grossman, Andrew, MD, Saeed, Shehzad, MD, Kay, Marsha, MD, Carvalho, Ryan, MD, Keljo, David, MD, PhD, Pfefferkorn, Marian, MD, Faubion, William, MD, Kappelman, Michael, MD, Sudel, Boris, MD, Schaefer, Marc E., MD, Markowitz, James, MD, Hyams, Jeffrey S., MD

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Cognitive-Behavioral Therapy for Adolescents With Inflammatory Bowel Disease and Subsyndromal Depression von SZIGETHY, EVA, M.D, KENNEY, ELYSE, B.A, CARPENTER, JOHANNA, B.A, HARDY, DIANA M., M.S, FAIRCLOUGH, DIANE, Dr.PH, BOUSVAROS, ATHOS, M.D, KELJO, DAVID, M.D, WEISZ, JOHN, Ph.D, BEARDSLEE, WILLIAM R., M.D, NOLL, ROBERT, Ph.D, DeMASO, DAVID RAY, M.D

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Characterization of Relations Among Sleep, Inflammation, and Psychiatric Dysfunction in Depressed Youth With Crohn Disease von Benhayon, David, Youk, Ada, McCarthy, F. Nicole, Davis, Stephanie, Keljo, David J., Bousvaros, Athos, Fairclough, Diane, Kupfer, David, Buysse, Daniel J., Szigethy, Eva M.

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Depression Subtypes in Pediatric Inflammatory Bowel Disease von Szigethy, Eva M., Youk, Ada O., Benhayon, David, Fairclough, Diane L., Newara, Melissa C., Kirshner, Margaret A., Bujoreanu, Simona I., Mrakotsky, Christine, Bousvaros, Athos, Srinath, Arvind I., Keljo, David J., Kupfer, David J., DeMaso, David R.

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Predictors of Depression in Youth With Crohn Disease von Clark, Jeffrey G., Srinath, Arvind I., Youk, Ada O., Kirshner, Margaret A., McCarthy, F. Nicole, Keljo, David J., Bousvaros, Athos, DeMaso, David R., Szigethy, Eva M.

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Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis von Haberman, Yael, Schirmer, Melanie, Dexheimer, Phillip J., Karns, Rebekah, Braun, Tzipi, Kim, Mi-Ok, Walters, Thomas D., Baldassano, Robert N., Noe, Joshua D., Rosh, Joel, Markowitz, James, Crandall, Wallace V., Mack, David R., Griffiths, Anne M., Heyman, Melvin B., Baker, Susan S., Kellermayer, Richard, Moulton, Dedrick, Patel, Ashish S., Gulati, Ajay S., Steiner, Steven J., LeLeiko, Neal, Otley, Anthony, Oliva-Hemker, Maria, Ziring, David, Kirschner, Barbara S, Keljo, David J., Guthery, Stephen L., Cohen, Stanley A., Snapper, Scott, Evans, Jonathan, Dubinsky, Marla, Aronow, Bruce, Hyams, Jeffrey S., Kugathasan, Subra, Huttenhower, Curtis, Xavier, Ramnik J., Denson, Lee A.

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Dissecting Allele Architecture of Early Onset IBD Using High-Density Genotyping von Cutler, David J, Zwick, Michael E, Okou, David T, Prahalad, Sampath, Walters, Thomas, Guthery, Stephen L, Dubinsky, Marla, Baldassano, Robert, Crandall, Wallace V, Rosh, Joel, Markowitz, James, Stephens, Michael, Kellermayer, Richard, Pfefferkorn, Marian, Heyman, Melvin B, LeLeiko, Neal, Mack, David, Moulton, Dedrick, Kappelman, Michael D, Kumar, Archana, Prince, Jarod, Bose, Promita, Mondal, Kajari, Ramachandran, Dhanya, Bohnsack, John F, Griffiths, Anne M, Haberman, Yael, Essers, Jonah, Thompson, Susan D, Aronow, Bruce, Keljo, David J, Hyams, Jeffrey S, Denson, Lee A, Kugathasan, Subra

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Free and Bioavailable 25-Hydroxyvitamin D Concentrations are Associated With Disease Activity in Pediatric Patients With Newly Diagnosed Treatment Naïve Ulcerative Colitis von Sauer, Cary G, Loop, Matthew S, Venkateswaran, Suresh, Tangpricha, Vin, Ziegler, Thomas R, Dhawan, Ashish, McCall, Courtney, Bonkowski, Erin, Mack, David R, Boyle, Brendan, Griffiths, Anne M, Leleiko, Neal S, Keljo, David J, Markowitz, James, Baker, Susan S, Rosh, Joel, Baldassano, Robert N, Davis, Sonia, Patel, Shiven, Wang, Jessie, Marquis, Alison, Spada, Krista L, Kugathasan, Subra, Walters, Thomas, Hyams, Jeffrey S, Denson, Lee A

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6.20 BRIEF BEHAVIORAL THERAPY AND BUPROPION FOR SLEEP AND FATIGUE IN ADOLESCENTS AND YOUNG ADULTS WITH INFLAMMATORY BOWEL DISEASE von Szigethy, Eva, MD, PhD, Mcauliff, Katheryn, BA, Strassburger, Meredith, MA, Hashash, Jana, Vachon, Ashley, MD, Rode, Noelle M., BS, Keljo, David J., MD, PhD, Youk, Ada O., PhD, Regueiro, Miguel, MD, Binion, David, MD, Lotrich, Frank, MD, Germain, Anne, PhD, Hall, Martica, PhD

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Course and Treatment of Perianal Disease in Children Newly Diagnosed with Crohn's Disease von Keljo, David J., Markowitz, James, Langton, Christine, Lerer, Trudy, Bousvaros, Athos, Carvalho, Ryan, Crandall, Wallace, Evans, Jonathan, Griffiths, Anne, Kay, Marsha, Kugathasan, Subra, LeLeiko, Neal, Mack, David, Mamula, Petar, Moyer, Susan M., Oliva-Hemker, Maria, Otley, Anthony, Pfefferkorn, Marian, Rosh, Joel, Hyams, Jeffrey S.

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Retrospective Cohort Study of Methotrexate Use in the Treatment of Pediatric Crohn's Disease von Sunseri, Whitney, Hyams, Jeffrey S., Lerer, Trudy, Mack, David R., Griffiths, Anne M., Otley, Anthony R., Rosh, Joel R., Carvalho, Ryan, Grossman, Andrew B., Cabrera, Jose, Pfefferkorn, Marian D., Rick, James, Leleiko, Neal S., Hitch, Meredith C., Oliva-Hemker, Maria, Saeed, Shehzad A., Kappelman, Michael, Markowitz, James, Keljo, David J.

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