Clinical Pharmacokinetics of Therapeutic Monoclonal Antibodies von Keizer, Ron J., Huitema, Alwin D. R., Schellens, Jan H. M., Beijnen, Jos H.

Volltext

Mathematical model and tool to explore shorter multi-drug therapy options for active pulmonary tuberculosis von Fors, John, Strydom, Natasha, Fox, William S., Keizer, Ron J., Savic, Radojka M.

Volltext

A hybrid machine learning/pharmacokinetic approach outperforms maximum a posteriori Bayesian estimation by selectively flattening model priors von Hughes, Jasmine H., Keizer, Ron J.

Volltext

Clinical Decision Support for Precision Dosing: Opportunities for Enhanced Equity and Inclusion in Health Care von Hughes, Jasmine H., Woo, Kara H., Keizer, Ron J., Goswami, Srijib

Volltext

Maximum a posteriori Bayesian methods out-perform non-compartmental analysis for busulfan precision dosing von Hughes, Jasmine H., Long-Boyle, Janel, Keizer, Ron J.

Volltext

Continuous Learning in Model‐Informed Precision Dosing: A Case Study in Pediatric Dosing of Vancomycin von Hughes, Jasmine H., Tong, Dominic M. H., Lucas, Sarah Scarpace, Faldasz, Jonathan D., Goswami, Srijib, Keizer, Ron J.

Volltext

Model-Informed Precision Dosing of Vancomycin in Hospitalized Children: Implementation and Adoption at an Academic Children's Hospital von Frymoyer, Adam, Schwenk, Hayden T., Zorn, Yvonne, Bio, Laura, Moss, Jeffrey D., Chasmawala, Bhavin, Faulkenberry, Joshua, Goswami, Srijib, Keizer, Ron J., Ghaskari, Shabnam

Volltext

Model‐Informed Precision Dosing at the Bedside: Scientific Challenges and Opportunities von Keizer, Ron J., ter Heine, Rob, Frymoyer, Adam, Lesko, Lawrence J., Mangat, Ranvir, Goswami, Srijib

Volltext

Evaluation of Neonatal and Paediatric Vancomycin Pharmacokinetic Models and the Impact of Maturation and Serum Creatinine Covariates in a Large Multicentre Data Set von Hughes, Jasmine H., Tong, Dominic M. H., Faldasz, Jonathan D., Frymoyer, Adam, Keizer, Ron J.

Volltext

Personalized Antifungal Therapy Through Model-Informed Precision Dosing of Posaconazole von Jansen, Anouk M. E., Snijdelaar, Kim, Keizer, Ron J., Spriet, Isabel, Dreesen, Erwin, Brüggemann, Roger J. M., ter Heine, Rob

Volltext

Assessment of a Model-Informed Precision Dosing Platform Use in Routine Clinical Care for Personalized Busulfan Therapy in the Pediatric Hematopoietic Cell Transplantation (HCT) Po... von Shukla, Praveen, Goswami, Srijib, Keizer, Ron J., Winger, Beth Apsel, Kharbanda, Sandhya, Dvorak, Christopher C., Long-Boyle, Janel

Volltext

Bayesian clinical decision support-guided versus clinician-guided vancomycin dosing in attainment of targeted pharmacokinetic parameters in a paediatric population von Hughes, David M, Goswami, Srijib, Keizer, Ron J, Hughes, Maria-Stephanie A, Faldasz, Jonathan D

Volltext

Personalized Tuberculosis Treatment Through Model-Informed Dosing of Rifampicin von van Beek, Stijn W., ter Heine, Rob, Keizer, Ron J., Magis-Escurra, Cecile, Aarnoutse, Rob E., Svensson, Elin M.

Volltext

Prospective validation of a model‐informed precision dosing tool for vancomycin in intensive care patients von Heine, Rob, Keizer, Ron J., Steeg, Krista, Smolders, Elise J., Luin, Matthijs, Derijks, Hieronymus J., Jager, Cornelis P.C., Frenzel, Tim, Brüggemann, Roger

Volltext

The Effect of Famotidine, a MATE1-Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin von Hibma, Jennifer E., Zur, Arik A., Castro, Richard A., Wittwer, Matthias B., Keizer, Ron J., Yee, Sook Wah, Goswami, Srijib, Stocker, Sophie L., Zhang, Xuexiang, Huang, Yong, Brett, Claire M., Savic, Radojka M., Giacomini, Kathleen M.

Volltext

Get Real: Integration of Real‐World Data to Improve Patient Care von Keizer, Ron J., Dvergsten, Erik, Kolacevski, Andrej, Black, Aaron, Karovic, Sanja, Goswami, Srijib, Maitland, Michael L.

Volltext

Performance of Eight Infliximab Population Pharmacokinetic Models in a Cohort of Dutch Children with Inflammatory Bowel Disease von Bevers, Nanja C., Keizer, Ron J., Wong, Dennis R., Aliu, Arta, Pierik, Marieke J., Derijks, Luc J. J., van Rheenen, Patrick F.

Volltext

Piraña and PCluster: A modeling environment and cluster infrastructure for NONMEM von Keizer, Ron J, van Benten, Michel, Beijnen, Jos H, Schellens, Jan H.M, Huitema, Alwin D.R

Volltext

Model-informed dose optimization of mycophenolic acid in pediatric kidney transplant patients von Heida, Astrid, Jager, Nynke G. L., Aarnoutse, Rob E., de Winter, Brenda C. M., de Jong, Huib, Keizer, Ron J., Cornelissen, Elisabeth A. M., ter Heine, Rob

Volltext

Clinical decision support for chemotherapy‐induced neutropenia using a hybrid pharmacodynamic/machine learning model von Hughes, Jasmine H., Tong, Dominic M. H., Burns, Vanessa, Daly, Bobby, Razavi, Pedram, Boelens, Jaap J., Goswami, Srijib, Keizer, Ron J.

Volltext