Chemically induced oxidative stress increases polyamine levels by activating the transcription of ornithine decarboxylase and spermidine/spermine-N1-acetyltransferase in human hepa... von Smirnova, Olga A., Isaguliants, Maria G., Hyvonen, Mervi T., Keinanen, Tuomo A., Tunitskaya, Vera L., Vepsalainen, Jouko, Alhonen, Leena, Kochetkov, Sergey N., Ivanov, Alexander V.

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Activation of Polyamine Catabolism by N1,N11-Diethylnorspermine in Hepatic HepaRG Cells Induces Dedifferentiation and Mesenchymal-Like Phenotype von Ivanova, Olga N., Snezhkina, Anastasiya V., Krasnov, George S., Valuev-Elliston, Vladimir T., Khomich, Olga A., Khomutov, Alexey R., Keinanen, Tuomo A., Alhonen, Leena, Bartosch, Birke, Kudryavtseva, Anna V., Kochetkov, Sergey N., Ivanov, Alexander V.

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Continuous oxidative stress due to activation of polyamine catabolism accelerates aging and protects against hepatotoxic insults von Cerrada-Gimenez, Marc, Pietilä, Marko, Loimas, Suvikki, Pirinen, Eija, Hyvönen, Mervi T, Keinänen, Tuomo A, Jänne, Juhani, Alhonen, Leena

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Novel fleximer pyrazole-containing adenosine analogues: chemical, enzymatic and highly efficient biotechnological synthesis von Khandazhinskaya, Anastasia, Eletskaya, Barbara, Fateev, Ilja, Kharitonova, Maria, Konstantinova, Irina, Barai, Vladimir, Azhayev, Alex, Hyvonen, Mervi T, Keinanen, Tuomo A, Kochetkov, Sergey, Seley-Radtke, Katherine, Khomutov, Alex, Matyugina, Elena

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Hepatitis C virus alters metabolism of biogenic polyamines by affecting expression of key enzymes of their metabolism von Smirnova, Olga A., Keinanen, Tuomo A., Ivanova, Olga N., Hyvonen, Mervi T., Khomutov, Alex R., Kochetkov, Sergey N., Bartosch, Birke, Ivanov, Alexander V.

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Unforeseen Possibilities To Investigate the Regulation of Polyamine Metabolism Revealed by Novel C‑Methylated Spermine Derivatives von Khomutov, Maxim, Hyvönen, Mervi T, Simonian, Alina, Formanovsky, Andrey A, Mikhura, Irina V, Chizhov, Alexander O, Kochetkov, Sergey N, Alhonen, Leena, Vepsäläinen, Jouko, Keinänen, Tuomo A, Khomutov, Alex R

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Polyamine Metabolism Is Sensitive to Glycolysis Inhibition in Human Neuroblastoma Cells von Ruiz-Pérez, M. Victoria, Medina, Miguel Ángel, Urdiales, José Luis, Keinänen, Tuomo A., Sánchez-Jiménez, Francisca

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Role of Polyamine-Induced Dimerization of Antizyme in Its Cellular Functions von Hyvönen, Mervi T, Smirnova, Olga A, Mitkevich, Vladimir A, Tunitskaya, Vera L, Khomutov, Maxim, Karpov, Dmitry S, Korolev, Sergey P, Häkkinen, Merja R, Pietilä, Marko, Gottikh, Marina B, Vepsäläinen, Jouko, Alhonen, Leena, Makarov, Alexander A, Kochetkov, Sergey N, Wallace, Heather M, Keinänen, Tuomo A, Khomutov, Alex R

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Hydroxylamine Analogue of Agmatine: Magic Bullet for Arginine Decarboxylase von Hyvönen, Mervi T, Keinänen, Tuomo A, Nuraeva, Gulgina K, Yanvarev, Dmitry V, Khomutov, Maxim, Khurs, Elena N, Kochetkov, Sergey N, Vepsäläinen, Jouko, Zhgun, Alexander A, Khomutov, Alex R

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Abstract 3765: Induction of amineoxidases as a possible mechanism of action of tamoxifen metabolites von Thomas, T. J., Keinanen, Tuomo A., Hyvonen, Mervi T.

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Urinary Polyamines as Biomarkers for Ovarian Cancer von Niemi, Riikka Johanna, Roine, Antti N, Häkkinen, Merja R, Kumpulainen, Pekka S, Keinänen, Tuomo A, Vepsäläinen, Jouko J, Lehtimäki, Terho, Oksala, Niku K, Mäenpää, Johanna U

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Triethylenetetramine modulates polyamine and energy metabolism and inhibits cancer cell proliferation von Hyvönen, Mervi T, Ucal, Sebahat, Pasanen, Markku, Peräniemi, Sirpa, Weisell, Janne, Khomutov, Maxim, Khomutov, Alex R, Vepsäläinen, Jouko, Alhonen, Leena, Keinänen, Tuomo A

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Controlling of N -alkylpolyamine analogue metabolism by selective deuteration von Ucal, Sebahat, Häkkinen, Merja R, Alanne, Aino-Liisa, Alhonen, Leena, Vepsäläinen, Jouko, Keinänen, Tuomo A, Hyvönen, Mervi T

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Spermidine promotes adipogenesis of 3T3-L1 cells by preventing interaction of ANP32 with HuR and PP2A von Hyvönen, Mervi T, Koponen, Taina, Weisell, Janne, Pietilä, Marko, Khomutov, Alex R, Vepsäläinen, Jouko, Alhonen, Leena, Keinänen, Tuomo A

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Analysis of free, mono- and diacetylated polyamines from human urine by LC–MS/MS von Häkkinen, Merja R., Roine, Antti, Auriola, Seppo, Tuokko, Antti, Veskimäe, Erik, Keinänen, Tuomo A., Lehtimäki, Terho, Oksala, Niku, Vepsäläinen, Jouko

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α-Difluoromethylornithine-Induced Cytostasis is Reversed by Exogenous Polyamines, Not by Thymidine Supplementation von Hyvönen, Mervi T., Khomutov, Maxim, Vepsäläinen, Jouko, Khomutov, Alex R., Keinänen, Tuomo A.

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Controlling the regioselectivity and stereospecificity of FAD-dependent polyamine oxidases with the use of amine-attached guide molecules as conformational modulators von Keinänen, Tuomo A, Grigorenko, Nikolay, Khomutov, Alex R, Huang, Qingqiu, Uimari, Anne, Alhonen, Leena, Hyvönen, Mervi T, Vepsäläinen, Jouko

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Tamoxifen metabolite endoxifen interferes with the polyamine pathway in breast cancer von Thomas, T. J., Thomas, Thresia, John, Shali, Hsu, Hui-Chen, Yang, PingAr, Keinänen, Tuomo A., Hyvönen, Mervi T.

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Enantiomers of 3‑Methylspermidine Selectively Modulate Deoxyhypusine Synthesis and Reveal Important Determinants for Spermidine Transport von Hyvönen, Mervi T, Khomutov, Maxim, Petit, Marine, Weisell, Janne, Kochetkov, Sergey N, Alhonen, Leena, Vepsäläinen, Jouko, Khomutov, Alex R, Keinänen, Tuomo A

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The Use of Novel C-Methylated Spermidine Derivatives To Investigate the Regulation of Polyamine Metabolism von Hyvönen, Mervi T, Keinänen, Tuomo A, Khomutov, Maxim, Simonian, Alina, Weisell, Janne, Kochetkov, Sergey N, Vepsäläinen, Jouko, Alhonen, Leena, Khomutov, Alex R

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