Alirocumab, evinacumab, and atorvastatin triple therapy regresses plaque lesions and improves lesion composition in mice[S] von Pouwer, Marianne G., Pieterman, Elsbet J., Worms, Nicole, Keijzer, Nanda, Jukema, J. Wouter, Gromada, Jesper, Gusarova, Viktoria, Princen, Hans M.G.

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TRAK/Milton Motor-Adaptor Proteins Steer Mitochondrial Trafficking to Axons and Dendrites von van Spronsen, Myrrhe, Mikhaylova, Marina, Lipka, Joanna, Schlager, Max A., van den Heuvel, Dave J., Kuijpers, Marijn, Wulf, Phebe S., Keijzer, Nanda, Demmers, Jeroen, Kapitein, Lukas C., Jaarsma, Dick, Gerritsen, Hans C., Akhmanova, Anna, Hoogenraad, Casper C.

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BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures von Splinter, Daniël, Razafsky, David S, Schlager, Max A, Serra-Marques, Andrea, Grigoriev, Ilya, Demmers, Jeroen, Keijzer, Nanda, Jiang, Kai, Poser, Ina, Hyman, Anthony A, Hoogenraad, Casper C, King, Stephen J, Akhmanova, Anna

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Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry von Splinter, Daniël, Tanenbaum, Marvin E, Lindqvist, Arne, Jaarsma, Dick, Flotho, Annette, Yu, Ka Lou, Grigoriev, Ilya, Engelsma, Dieuwke, Haasdijk, Elize D, Keijzer, Nanda, Demmers, Jeroen, Fornerod, Maarten, Melchior, Frauke, Hoogenraad, Casper C, Medema, René H, Akhmanova, Anna

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Kinesin-Binding Protein Controls Microtubule Dynamics and Cargo Trafficking by Regulating Kinesin Motor Activity von Kevenaar, Josta T., Bianchi, Sarah, van Spronsen, Myrrhe, Olieric, Natacha, Lipka, Joanna, Frias, Cátia P., Mikhaylova, Marina, Harterink, Martin, Keijzer, Nanda, Wulf, Phebe S., Hilbert, Manuel, Kapitein, Lukas C., de Graaff, Esther, Ahkmanova, Anna, Steinmetz, Michel O., Hoogenraad, Casper C.

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A Novel, Orally Bioavailable, Small-Molecule Inhibitor of PCSK9 With Significant Cholesterol-Lowering Properties In Vivo von Suchowerska, Alexandra K., Stokman, Geurt, Palmer, James T., Coghlan, Phillip A., Pieterman, Elsbet J., Keijzer, Nanda, Lambert, Gilles, Chemello, Kevin, Jaafar, Ali K., Parmar, Jasneet, Yan, Liping, Tong, Yingtao, Mu, Lin, Princen, Hans M.G., Bonnar, James, Evison, Benny J.

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Probing Intracellular Motor Protein Activity Using an Inducible Cargo Trafficking Assay von Kapitein, Lukas C., Schlager, Max A., van der Zwan, Wouter A., Wulf, Phebe S., Keijzer, Nanda, Hoogenraad, Casper C.

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Therapeutic Intervention with Anti-Complement Component 5 Antibody Does Not Reduce NASH but Does Attenuate Atherosclerosis and MIF Concentrations in Ldlr-/-.Leiden Mice von Seidel, Florine, Kleemann, Robert, van Duyvenvoorde, Wim, van Trigt, Nikki, Keijzer, Nanda, van der Kooij, Sandra, van Kooten, Cees, Verschuren, Lars, Menke, Aswin, Kiliaan, Amanda J., Winter, Johnathan, Hughes, Timothy R., Morgan, B. Paul, Baas, Frank, Fluiter, Kees, Morrison, Martine C.

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Pericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D-related protein 1 (BICDR-1) regulates neuritogenesis von Schlager, Max A, Kapitein, Lukas C, Grigoriev, Ilya, Burzynski, Grzegorz M, Wulf, Phebe S, Keijzer, Nanda, de Graaff, Esther, Fukuda, Mitsunori, Shepherd, Iain T, Akhmanova, Anna, Hoogenraad, Casper C

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NMDA receptor activation suppresses microtubule growth and spine entry von Kapitein, Lukas C, Yau, Kah Wai, Gouveia, Susana Montenegro, van der Zwan, Wouter A, Wulf, Phebe S, Keijzer, Nanda, Demmers, Jeroen, Jaworski, Jacek, Akhmanova, Anna, Hoogenraad, Casper C

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Myosin-V Opposes Microtubule-Based Cargo Transport and Drives Directional Motility on Cortical Actin von Kapitein, Lukas C., van Bergeijk, Petra, Lipka, Joanna, Keijzer, Nanda, Wulf, Phebe S., Katrukha, Eugene A., Akhmanova, Anna, Hoogenraad, Casper C.

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Proof-of-concept study for liver-directed miQURE technology in a dyslipidemic mouse model von Zancanella, Vanessa, Vallès, Astrid, Liefhebber, Jolanda M.P., Paerels, Lieke, Tornero, Carlos Vendrell, Wattimury, Hendrina, van der Zon, Tom, van Rooijen, Kristel, Golinska, Monika, Grevelink, Tamar, Ehlert, Erich, Pieterman, Elsbet Jantine, Keijzer, Nanda, Gerardus Princen, Hans Marinus, Stokman, Geurt, Liu, Ying Poi

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Proof-of-concept study for liver-directed miQURE technology in a dyslipidemic mouse model von Zancanella, Vanessa, Vallès, Astrid, Liefhebber, Jolanda M.P., Paerels, Lieke, Tornero, Carlos Vendrell, Wattimury, Hendrina, van der Zon, Tom, van Rooijen, Kristel, Golinska, Monika, Grevelink, Tamar, Ehlert, Erich, Pieterman, Elsbet Jantine, Keijzer, Nanda, Princen, Hans Marinus Gerardus, Stokman, Geurt, Liu, Ying Poi

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Translatability of mouse muscle-aging for humans: the role of sex von de Jong, Jelle C. B. C., Caspers, Martien P. M., Worms, Nicole, Keijzer, Nanda, Kleemann, Robert, Menke, Aswin L., Nieuwenhuizen, Arie G., Keijer, Jaap, Verschuren, Lars, van den Hoek, Anita M.

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A role for Bicaudal-D2 in radial cerebellar granule cell migration von Jaarsma, Dick, van den Berg, Robert, Wulf, Phebe S., van Erp, Susan, Keijzer, Nanda, Schlager, Max A., de Graaff, Esther, De Zeeuw, Chris I., Pasterkamp, R. Jeroen, Akhmanova, Anna, Hoogenraad, Casper C.

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Obicetrapib alone and in combination with ezetimibe reduces atherosclerotic lesion size and severity in ApoE3-Leiden.CETP mice von Inia, Jose, Keijzer, Nanda, Worms, Nicole, Van Nieuwkoop, Anita, Ditmarsch, Marc, Jukema, Wouter, Kastelein, John, Van Den Hoek, Anita, Stokman, Geurt, Pieterman, Elsbet, Princen, Hans

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Obicetrapib alone and in combination with ezetimibe reduces non-HDL-cholesterol by enhanced LDL-receptor-mediated VLDL clearance and increased net fecal sterol excretion in apoe3-l... von Inia, Jose, Keijzer, Nanda, Worms, Nicole, Van Nieuwkoop, Anita, Ditmarsch, Marc, Jukema, Wouter, Groen, Albert, Kastelein, John, Van Den Hoek, Anita, Stokman, Geurt, Pieterman, Elsbet, Princen, Hans

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Repeated weight cycling in obese mice improves hepatic inflammation von de Jong, Jelle C.B.C., Keijzer, Nanda, Worms, Nicole, Stokman, Geurt, van Trigt, Nikki, Menke, Aswin L., van den Hoek, Anita M.

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Obicetrapib Alone and with Ezetimibe Reduces Non-HDL-C by Enhanced LDL-Receptor-Mediated VLDL Clearance and Increased Net Fecal Sterol Excretion von Keijzer, Nanda, Worms, Nicole, van Nieuwkoop, Anita, Ditmarsch, Marc, Jukema, J. Wouter, Groen, Albert, Kastelein, John, Pieterman, Elsbet, Princen, Hans, Inia, José

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Therapeutic inhibition of complement component 5 does not reduce NASH progression but does attenuate atherosclerosis development in Ldlr-/-.Leiden mice von Seidel, Florine, Kleemann, Robert, van Duyvenvoorde, Wim, van Trigt, Nikki, Keijzer, Nanda, van der Kooij, Sandra, van Kooten, Cees, Verschuren, Lars, Menke, Aswin L., Winter, Johnathan, Hughes, Timothy, Morgan, Paul, Baas, Frank, Fluiter, Kees, Morrison, Martine C., Kiliaan, Amanda

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