Beyond Antibodies: B Cells and the OPG/RANK-RANKL Pathway in Health, Non-HIV Disease and HIV-Induced Bone Loss von Titanji, Kehmia

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Enhancing SIV-specific immunity in vivo by PD-1 blockade von Vanderford, Thomas H, Velu, Vijayakumar, Titanji, Kehmia, Ahmed, Rafi, Amara, Rama Rao, Lai, Lilin, Pladevega, Annette, Freeman, Gordon J, Husain, Sajid, Zhu, Baogong, Chennareddi, Lakshmi, Silvestri, Guido

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PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques von Dyavar Shetty, Ravi, Velu, Vijayakumar, Titanji, Kehmia, Bosinger, Steven E, Freeman, Gordon J, Silvestri, Guido, Amara, Rama Rao

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Dysregulated B cell expression of RANKL and OPG correlates with loss of bone mineral density in HIV infection von Titanji, Kehmia, Vunnava, Aswani, Sheth, Anandi N, Delille, Cecile, Lennox, Jeffrey L, Sanford, Sara E, Foster, Antonina, Knezevic, Andrea, Easley, Kirk A, Weitzmann, M Neale, Ofotokun, Ighovwerha

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Acute depletion of activated memory B cells involves the PD-1 pathway in rapidly progressing SIV-infected macaques von Titanji, Kehmia, Velu, Vijayakumar, Chennareddi, Lakshmi, Vijay-Kumar, Matam, Gewirtz, Andrew T, Freeman, Gordon J, Amara, Rama R

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Impact of etonogestrel implant use on T-cell and cytokine profiles in the female genital tract and blood von Haddad, Lisa B., Swaims-Kohlmeier, Alison, Mehta, C. Christina, Haaland, Richard E., Brown, Nakita L., Sheth, Anandi N., Chien, Hsin, Titanji, Kehmia, Achilles, Sharon L., Lupo, Davis, Hart, Clyde E., Ofotokun, Igho

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Bone, Brain, Heart study protocol: A resilient nested, tripartite prospective cohort study of the role of estrogen depletion on HIV pathology von Mehta, C Christina, Hagen, Kimberly S, Rubtsova, Anna A, Lahiri, Cecile D, Michopoulos, Vasiliki, Moran, Caitlin A, Haddad, Lisa B, Titanji, Kehmia, Collins, Lauren F, Quyyumi, Arshed A, Neigh, Gretchen, Shaw, Leslee J, Weitzmann, M Neale, Waller, Lance, Ofotokun, Ighovwerha

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The effect of age on CD4+ T-cell recovery in HIV-suppressed adult participants: a sub-study from AIDS Clinical Trial Group (ACTG) A5321 and the Bone Loss and Immune Reconstitution... von Chen, Jingxian, Titanji, Kehmia, Sheth, Anandi N, Gandhi, Rajesh, McMahon, Deborah, Ofotokun, Ighovwerha, Weitzmann, M Neale, De Paris, Kristina, Dumond, Julie B

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Mechanisms of hypergammaglobulinemia and impaired antigen-specific humoral immunity in HIV-1 infection von De Milito, Angelo, Nilsson, Anna, Titanji, Kehmia, Thorstensson, Rigmor, Reizenstein, Elisabet, Narita, Mitsuo, Grutzmeier, Sven, Sönnerborg, Anders, Chiodi, Francesca

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Primary HIV-1 infection sets the stage for important B lymphocyte dysfunctions von TITANJI, Kehmia, CHIODI, Francesca, BELLOCCO, Rino, SCHEPIS, Danika, OSORIO, Lyda, TASSANDIN, Chiara, TAMBUSSI, Giuseppe, GRUTZMEIER, Sven, LOPALCO, Lucia, DE MILITO, Angelo

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Immature/transitional B-cell expansion is associated with bone loss in HIV-infected individuals with severe CD4+ T-cell lymphopenia von Titanji, Kehmia, Ofotokun, Ighovwerha, Weitzmann, M. Neale

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3159 Bone Turnover Biomarkers May Discriminate Low Bone Mineral Density in HIV-Infected Adults von Collins, Lauren Frances, Sheth, Anandi, Moran, Caitlin, Ward, Laura, Titanji, Kehmia, Easley, Kirk, Lennox, Jeffrey, Neale Weitzmann, M., Ofotokun, Igho

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PD-1 blockade following ART interruption enhances control of pathogenic SIV in rhesus macaques von Velu, Vijayakumar, Titanji, Kehmia, Ahmed, Hasan, Shetty, Ravi Dyavar, Chennareddi, Lakshmi S, Freeman, Gordon J, Ahmed, Rafi, Amara, Rama Rao

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Role of T-cell reconstitution in HIV-1 antiretroviral therapy-induced bone loss von Ofotokun, Ighovwerha, Titanji, Kehmia, Vikulina, Tatyana, Roser-Page, Susanne, Yamaguchi, Masayoshi, Zayzafoon, Majd, Williams, Ifor R., Weitzmann, M. Neale

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Antiretroviral therapy induces a rapid increase in bone resorption that is positively associated with the magnitude of immune reconstitution in HIV infection von Ofotokun, Ighovwerha, Titanji, Kehmia, Vunnava, Aswani, Roser-Page, Susanne, Vikulina, Tatyana, Villinger, Francois, Rogers, Kenneth, Sheth, Anandi N, Lahiri, Cecile Delille, Lennox, Jeffrey L, Weitzmann, M Neale

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Cardiovascular Implications of Immune Disorders in Women von Moran, Caitlin A., Collins, Lauren F., Beydoun, Nour, Mehta, Puja K., Fatade, Yetunde, Isiadinso, Ijeoma, Lewis, Tené T., Weber, Brittany, Goldstein, Jill, Ofotokun, Igho, Quyyumi, Arshed, Choi, May Y., Titanji, Kehmia, Lahiri, Cecile D.

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Loss of memory B cells impairs maintenance of long-term serologic memory during HIV-1 infection von Titanji, Kehmia, De Milito, Angelo, Cagigi, Alberto, Thorstensson, Rigmor, Grützmeier, Sven, Atlas, Ann, Hejdeman, Bo, Kroon, Frank P., Lopalco, Lucia, Nilsson, Anna, Chiodi, Francesca

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T-cell receptor activator of nuclear factor-κB ligand/osteoprotegerin imbalance is associated with HIV-induced bone loss in patients with higher CD4+ T-cell counts von Titanji, Kehmia, Vunnava, Aswani, Foster, Antonina, Sheth, Anandi N, Lennox, Jeffrey L, Knezevic, Andrea, Shenvi, Neeta, Easley, Kirk A, Ofotokun, Ighovwerha, Weitzmann, M Neale

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Antiretroviral Therapy–Induced Bone Loss Is Durably Suppressed by a Single Dose of Zoledronic Acid in Treatment-Naive Persons with Human Immunodeficiency Virus Infection: A Phase I... von Ofotokun, Ighovwerha, Collins, Lauren F, Titanji, Kehmia, Foster, Antonina, Moran, Caitlin A, Sheth, Anandi N, Lahiri, Cecile D, Lennox, Jeffrey L, Ward, Laura, Easley, Kirk A, Weitzmann, M Neale

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Midgut bacterial dynamics in Aedes aegypti von Terenius, Olle, Lindh, Jenny M., Eriksson-Gonzales, Karolina, Bussière, Luc, Laugen, Ane T., Bergquist, Helen, Titanji, Kehmia, Faye, Ingrid

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