Abstract 453: MEK activation is associated with a molecular subgroup in high grade serous ovarian cancer von McCabe, Nuala, Gourley, Charlie, McGavigan, Andrena, Michie, Caroline O., McGivern, Niamh, Churchman, Michael, O’Brien, Eamonn J., Hill, Laura, Davison, Timothy S., Williams, Alistair, McCluggage, Glenn, Keating, Karen E., Harkin, Denis P., Kennedy, Richard D.

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Activation of and dependence on ataxia telangiectasia mutated kinase in PTEN-deficient tumor cells von McCabe, Nuala, Walker, Steven M., Goffard, Nicolas, Wikstrom, Katarina, Greenan, Caroline, McLean, Estelle, McDyer, Fionnuala A, Keating, Karen E, James, Iain, Harrison, Timothy, Mullan, Paul B, Harkin, D. Paul, Chen, Clark, Kennedy, Richard D.

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Predicting adult weight change in the real world: a systematic review and meta-analysis accounting for compensatory changes in energy intake or expenditure von Dhurandhar, E J, Kaiser, K A, Dawson, J A, Alcorn, A S, Keating, K D, Allison, D B

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Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine von Baden, Lindsey R, El Sahly, Hana M, Essink, Brandon, Kotloff, Karen, Frey, Sharon, Novak, Rick, Diemert, David, Spector, Stephen A, Rouphael, Nadine, Creech, C. Buddy, McGettigan, John, Khetan, Shishir, Segall, Nathan, Solis, Joel, Brosz, Adam, Fierro, Carlos, Schwartz, Howard, Neuzil, Kathleen, Corey, Larry, Gilbert, Peter, Janes, Holly, Follmann, Dean, Marovich, Mary, Mascola, John, Polakowski, Laura, Ledgerwood, Julie, Graham, Barney S, Bennett, Hamilton, Pajon, Rolando, Knightly, Conor, Leav, Brett, Deng, Weiping, Zhou, Honghong, Han, Shu, Ivarsson, Melanie, Miller, Jacqueline, Zaks, Tal

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Clinical Effectiveness of Elexacaftor/Tezacaftor/Ivacaftor in People with Cystic Fibrosis: A Clinical Trial von Nichols, David P, Paynter, Alex C, Heltshe, Sonya L, Donaldson, Scott H, Frederick, Carla A, Freedman, Steven D, Gelfond, Daniel, Hoffman, Lucas R, Kelly, Andrea, Narkewicz, Michael R, Pittman, Jessica E, Ratjen, Felix, Rosenfeld, Margaret, Sagel, Scott D, Schwarzenberg, Sarah Jane, Singh, Pradeep K, Solomon, George M, Stalvey, Michael S, Clancy, John P, Kirby, Shannon, Van Dalfsen, Jill M, Kloster, Margaret H, Rowe, Steven M

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SOCS1 is a critical checkpoint in immune homeostasis, inflammation and tumor immunity von Bidgood, Grace M, Keating, Narelle, Doggett, Karen, Nicholson, Sandra E

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Subclinical atherosclerosis and increased risk of hearing impairment von Fischer, Mary E, Schubert, Carla R, Nondahl, David M, Dalton, Dayna S, Huang, Guan-Hua, Keating, Brendan J, Klein, Barbara E.K, Klein, Ronald, Tweed, Ted S, Cruickshanks, Karen J

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Search for Evidence‐Based Approaches for the Prevention and Palliation of Hand–Foot Skin Reaction (HFSR) Caused by the Multikinase Inhibitors (MKIs) von Anderson, Roger, Jatoi, Aminah, Robert, Caroline, Wood, Laura S., Keating, Karen N., Lacouture, Mario E.

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How Does Exercise, With and Without Diet, Improve Pain and Function in Knee Osteoarthritis? A Secondary Analysis of a Randomized Controlled Trial Exploring Potential Mediators of E... von Lawford, Belinda J, Hinman, Rana S, McManus, Fiona, Lamb, Karen E, Egerton, Thorlene, Keating, Catherine, Brown, Courtney, Oliver, Kathryn, Bennell, Kim L

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Integrative multi-omics profiling in human decedents receiving pig heart xenografts von Schmauch, Eloi, Piening, Brian, Mohebnasab, Maedeh, Xia, Bo, Zhu, Chenchen, Stern, Jeffrey, Zhang, Weimin, Dowdell, Alexa K., Kim, Jacqueline I., Andrijevic, David, Khalil, Karen, Jaffe, Ian S., Loza, Bao-Li, Gragert, Loren, Camellato, Brendan R., Oliveira, Michelli F., O’Brien, Darragh P., Chen, Han M., Weldon, Elaina, Gao, Hui, Gandla, Divya, Chang, Andrew, Bhatt, Riyana, Gao, Sarah, Lin, Xiangping, Reddy, Kriyana P., Kagermazova, Larisa, Habara, Alawi H., Widawsky, Sophie, Liang, Feng-Xia, Sall, Joseph, Loupy, Alexandre, Heguy, Adriana, Taylor, Sarah E. B., Zhu, Yinan, Michael, Basil, Jiang, Lihua, Jian, Ruiqi, Chong, Anita S., Fairchild, Robert L., Linna-Kuosmanen, Suvi, Kaikkonen, Minna U., Tatapudi, Vasishta, Lorber, Marc, Ayares, David, Mangiola, Massimo, Narula, Navneet, Moazami, Nader, Pass, Harvey, Herati, Ramin S., Griesemer, Adam, Kellis, Manolis, Snyder, Michael P., Montgomery, Robert A., Boeke, Jef D., Keating, Brendan J.

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The Simons Observatory Large Aperture Telescope Receiver von Zhu, Ningfeng, Bhandarkar, Tanay, Coppi, Gabriele, Kofman, Anna M., Orlowski-Scherer, John L., Xu, Zhilei, Adachi, Shunsuke, Ade, Peter, Aiola, Simone, Austermann, Jason, Bazarko, Andrew O., Beall, James A., Bhimani, Sanah, Bond, J. Richard, Chesmore, Grace E., Choi, Steve K., Connors, Jake, Cothard, Nicholas F., Devlin, Mark, Dicker, Simon, Dober, Bradley, Duell, Cody J., Duff, Shannon M., Dünner, Rolando, Fabbian, Giulio, Galitzki, Nicholas, Gallardo, Patricio A., Golec, Joseph E., Haridas, Saianeesh K., Harrington, Kathleen, Healy, Erin, Ho, Shuay-Pwu Patty, Huber, Zachary B., Hubmayr, Johannes, Iuliano, Jeffrey, Johnson, Bradley R., Keating, Brian, Kiuchi, Kenji, Koopman, Brian J., Lashner, Jack, Lee, Adrian T., Li, Yaqiong, Limon, Michele, Link, Michael, Lucas, Tammy J, McCarrick, Heather, Moore, Jenna, Nati, Federico, Newburgh, Laura B., Niemack, Michael D., Pierpaoli, Elena, Randall, Michael J., Sarmiento, Karen Perez, Saunders, Lauren J., Seibert, Joseph, Sierra, Carlos, Sonka, Rita, Spisak, Jacob, Sutariya, Shreya, Tajima, Osamu, Teply, Grant P., Thornton, Robert J., Tsan, Tran, Tucker, Carole, Ullom, Joel, Vavagiakis, Eve M., Vissers, Michael R., Walker, Samantha, Westbrook, Benjamin, Wollack, Edward J., Zannoni, Mario

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Oral decitabine–cedazuridine versus intravenous decitabine for myelodysplastic syndromes and chronic myelomonocytic leukaemia (ASCERTAIN): a registrational, randomised, crossover,... von Garcia-Manero, Guillermo, McCloskey, James, Griffiths, Elizabeth A, Yee, Karen W L, Zeidan, Amer M, Al-Kali, Aref, Deeg, H Joachim, Patel, Prapti A, Sabloff, Mitchell, Keating, Mary-Margaret, Zhu, Nancy, Gabrail, Nashat Y, Fazal, Salman, Maly, Joseph, Odenike, Olatoyosi, Kantarjian, Hagop, DeZern, Amy E, O’Connell, Casey L, Roboz, Gail J, Busque, Lambert, Buckstein, Rena, Amin, Harshad, Randhawa, Jasleen, Leber, Brian, Shastri, Aditi, Dao, Kim-Hien, Oganesian, Aram, Hao, Yong, Keer, Harold N, Azab, Mohammad, Savona, Michael R

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Clinical, Safety, and Economic Evidence in Radioactive Iodine–Refractory Differentiated Thyroid Cancer: A Systematic Literature Review von Anderson, Roger T., Linnehan, John E., Tongbram, Vanita, Keating, Karen, Wirth, Lori J.

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Assessment of Abdominal Fat Compartments Using DXA in Premenopausal Women From Anorexia Nervosa to Morbid Obesity von Bredella, Miriam A., Gill, Corey M., Keating, Leigh K., Torriani, Martin, Anderson, Ellen J., Punyanitya, Mark, Wilson, Kevin E., Kelly, Thomas L., Miller, Karen K.

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Autologous blood cell transplantation versus HLA-identical sibling transplantation for acute myeloid leukemia in first complete remission: a registry study from the Center for Inte... von Keating, Armand, DaSilva, Gisela, Pérez, Waleska S, Gupta, Vikas, Cutler, Corey S, Ballen, Karen K, Cairo, Mitchell S, Camitta, Bruce M, Champlin, Richard E, Gajewski, James L, Lazarus, Hillard M, Lill, Michael, Marks, David I, Nabhan, Chadi, Schiller, Gary J, Socie, Gerald, Szer, Jeffrey, Tallman, Martin S, Weisdorf, Daniel J

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Pig-to-human heart xenotransplantation in two recently deceased human recipients von Moazami, Nader, Stern, Jeffrey M., Khalil, Karen, Kim, Jacqueline I., Narula, Navneet, Mangiola, Massimo, Weldon, Elaina P., Kagermazova, Larisa, James, Les, Lawson, Nikki, Piper, Greta L., Sommer, Philip M., Reyentovich, Alex, Bamira, Daniel, Saraon, Tajinderpal, Kadosh, Bernard S., DiVita, Michael, Goldberg, Randal I., Hussain, Syed T., Chan, Justin, Ngai, Jennie, Jan, Thomas, Ali, Nicole M., Tatapudi, Vasishta S., Segev, Dorry L., Bisen, Shivani, Jaffe, Ian S., Piegari, Benjamin, Kowalski, Haley, Kokkinaki, Maria, Monahan, Jeffrey, Sorrells, Lori, Burdorf, Lars, Boeke, Jef D., Pass, Harvey, Goparaju, Chandra, Keating, Brendan, Ayares, David, Lorber, Marc, Griesemer, Adam, Mehta, Sapna A., Smith, Deane E., Montgomery, Robert A.

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Cross-laboratory validation of the OncoScan® FFPE Assay, a multiplex tool for whole genome tumour profiling von Foster, Joseph M, Oumie, Assa, Togneri, Fiona S, Vasques, Fabiana Ramos, Hau, Debra, Taylor, Morag, Tinkler-Hundal, Emma, Southward, Katie, Medlow, Paul, McGreeghan-Crosby, Keith, Halfpenny, Iris, McMullan, Dominic J, Quirke, Phil, Keating, Katherine E, Griffiths, Mike, Spink, Karen G, Brew, Fiona

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ATM associates with and phosphorylates p53: mapping the region of interaction von Khanna, Kum Kum, Keating, Katherine E, Kozlov, Sergei, Scott, Shaun, Gatei, Magtouf, Hobson, Karen, Taya, Yoichi, Gabrielli, Brian, Chan, Doug, Lees-Miller, Susan P, Lavin, Martin F

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Same-Day Vs Consecutive-Day Precision Error of Dual-Energy X-Ray Absorptiometry for Interpreting Body Composition Change in Resistance-Trained Athletes von Zemski, Adam J., Hind, Karen, Keating, Shelley E., Broad, Elizabeth M., Marsh, Damian J., Slater, Gary J.

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The SOCS1 KIR and SH2 domain are both required for suppression of cytokine signaling in vivo von Doggett, Karen, Keating, Narelle, Dehkhoda, Farhad, Bidgood, Grace M., Meza Guzman, Lizeth G., Leong, Evelyn, Kueh, Andrew, Nicola, Nicos A., Kershaw, Nadia J., Babon, Jeffrey J., Alexander, Warren S., Nicholson, Sandra E.

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