Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells von Basso, Katia, Saito, Masumichi, Sumazin, Pavel, Margolin, Adam A., Wang, Kai, Lim, Wei-Keat, Kitagawa, Yukiko, Schneider, Christof, Alvarez, Mariano J., Califano, Andrea, Dalla-Favera, Riccardo

Volltext

NOTCH1 Directly Regulates c-MYC and Activates a Feed-Forward-Loop Transcriptional Network Promoting Leukemic Cell Growth von Palomero, Teresa, Lim, Wei Keat, Odom, Duncan T., Sulis, Maria Luisa, Real, Pedro J., Margolin, Adam, Barnes, Kelly C., O'Neil, Jennifer, Neuberg, Donna, Weng, Andrew P., Aster, Jon C., Sigaux, Francois, Soulier, Jean, Look, A. Thomas, Young, Richard A., Califano, Andrea, Ferrando, Adolfo A.

Volltext

Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma von Compagno, Mara, Lim, Wei Keat, Grunn, Adina, Nandula, Subhadra V., Brahmachary, Manisha, Shen, Qiong, Bertoni, Francesco, Ponzoni, Maurilio, Scandurra, Marta, Califano, Andrea, Bhagat, Govind, Chadburn, Amy, Dalla-Favera, Riccardo, Pasqualucci, Laura

Volltext

The transcriptional network for mesenchymal transformation of brain tumours von Lasorella, Anna, Lim, Wei Keat, Carro, Maria Stella, Anne, Sandrine L, Alvarez, Mariano Javier, Doetsch, Fiona, Aldape, Ken, Iavarone, Antonio, Colman, Howard, Zhao, Xudong, Snyder, Evan Y, Sulman, Erik P, Califano, Andrea, Bollo, Robert J

Volltext

Atlas of the clinical genetics of human dilated cardiomyopathy von Haas, Jan, Frese, Karen S, Peil, Barbara, Kloos, Wanda, Keller, Andreas, Nietsch, Rouven, Feng, Zhu, Müller, Sabine, Kayvanpour, Elham, Vogel, Britta, Sedaghat-Hamedani, Farbod, Lim, Wei-Keat, Zhao, Xiaohong, Fradkin, Dmitriy, Köhler, Doreen, Fischer, Simon, Franke, Jennifer, Marquart, Sabine, Barb, Ioana, Li, Daniel Tian, Amr, Ali, Ehlermann, Philipp, Mereles, Derliz, Weis, Tanja, Hassel, Sarah, Kremer, Andreas, King, Vanessa, Wirsz, Emil, Isnard, Richard, Komajda, Michel, Serio, Alessandra, Grasso, Maurizia, Syrris, Petros, Wicks, Eleanor, Plagnol, Vincent, Lopes, Luis, Gadgaard, Tenna, Eiskjær, Hans, Jørgensen, Mads, Garcia-Giustiniani, Diego, Ortiz-Genga, Martin, Crespo-Leiro, Maria G, Deprez, Rondal H Lekanne Dit, Christiaans, Imke, van Rijsingen, Ingrid A, Wilde, Arthur A, Waldenstrom, Anders, Bolognesi, Martino, Bellazzi, Riccardo, Mörner, Stellan, Bermejo, Justo Lorenzo, Monserrat, Lorenzo, Villard, Eric, Mogensen, Jens, Pinto, Yigal M, Charron, Philippe, Elliott, Perry, Arbustini, Eloisa, Katus, Hugo A, Meder, Benjamin

Volltext

IL-4 and IL-13, not eosinophils, drive type 2 airway inflammation, remodeling and lung function decline von Scott, George, Asrat, Seblewongel, Allinne, Jeanne, Keat Lim, Wei, Nagashima, Kirsten, Birchard, Dylan, Srivatsan, Subhashini, Ajithdoss, Dharani K., Oyejide, Adelekan, Ben, Li-Hong, Walls, Johnathon, Le Floc'h, Audrey, Yancopoulos, George D., Murphy, Andrew J., Sleeman, Matthew A., Orengo, Jamie M.

Volltext

IL-33 blockade affects mediators of persistence and exacerbation in a model of chronic airway inflammation von Allinne, Jeanne, Scott, George, Lim, Wei Keat, Birchard, Dylan, Erjefält, Jonas S., Sandén, Caroline, Ben, Li-Hong, Agrawal, Amit, Kaur, Navneet, Kim, Jee Hae, Kamat, Vishal, Fury, Wen, Huang, Tammy, Stahl, Neil, Yancopoulos, George D., Murphy, Andrew J., Sleeman, Matthew A., Orengo, Jamie M.

Volltext

Comparative analysis of microarray normalization procedures: effects on reverse engineering gene networks von Lim, Wei Keat, Wang, Kai, Lefebvre, Celine, Califano, Andrea

Volltext

A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers von Califano, Andrea, Lefebvre, Celine, Rajbhandari, Presha, Alvarez, Mariano J, Bandaru, Pradeep, Lim, Wei Keat, Sato, Mai, Wang, Kai, Sumazin, Pavel, Kustagi, Manjunath, Bisikirska, Brygida C, Basso, Katia, Beltrao, Pedro, Krogan, Nevan, Gautier, Jean, Dalla-Favera, Riccardo

Volltext

Genome-wide identification of post-translational modulators of transcription factor activity in human B cells von Califano, Andrea, Wang, Kai, Saito, Masumichi, Bisikirska, Brygida C, Alvarez, Mariano J, Lim, Wei Keat, Rajbhandari, Presha, Shen, Qiong, Nemenman, Ilya, Basso, Katia, Margolin, Adam A, Klein, Ulf, Dalla-Favera, Riccardo

Volltext

A systems biology approach to prediction of oncogenes and molecular perturbation targets in B-cell lymphomas von Mani, Kartik M, Lefebvre, Celine, Wang, Kai, Lim, Wei Keat, Basso, Katia, Dalla-Favera, Riccardo, Califano, Andrea

Volltext

The N-Myc-DLL3 Cascade Is Suppressed by the Ubiquitin Ligase Huwe1 to Inhibit Proliferation and Promote Neurogenesis in the Developing Brain von Zhao, Xudong, D' Arca, Domenico, Lim, Wei Keat, Brahmachary, Manisha, Carro, Maria Stella, Ludwig, Thomas, Cardo, Carlos Cordon, Guillemot, Francois, Aldape, Ken, Califano, Andrea, Iavarone, Antonio, Lasorella, Anna

Volltext

Digital wearable insole-based identification of knee arthropathies and gait signatures using machine learning von Wipperman, Matthew F, Lin, Allen Z, Gayvert, Kaitlyn M, Lahner, Benjamin, Somersan-Karakaya, Selin, Wu, Xuefang, Im, Joseph, Lee, Minji, Koyani, Bharatkumar, Setliff, Ian, Thakur, Malika, Duan, Daoyu, Breazna, Aurora, Wang, Fang, Lim, Wei Keat, Halasz, Gabor, Urbanek, Jacek, Patel, Yamini, Atwal, Gurinder S, Hamilton, Jennifer D, Stuart, Samuel, Levy, Oren, Avbersek, Andreja, Alaj, Rinol, Hamon, Sara C, Harari, Olivier

Volltext

Spontaneous tumor regression mediated by human T cells in a humanized immune system mouse model von Patel, A. K., Dhanik, Ankur, Lim, Wei Keat, Adler, Christina, Ni, Min, Wei, Yi, Zhong, Maggie, Nguyen, Cindy, Zhong, Jun, Lu, Yi-Fen, Thurston, Gavin, Macdonald, Lynn, Murphy, Andrew, Gurer, Cagan, Frleta, Davor

Volltext

Butyrophilin-like 2 regulates site-specific adaptations of intestinal γδ intraepithelial lymphocytes von Panea, Casandra, Zhang, Ruoyu, VanValkenburgh, Jeffrey, Ni, Min, Adler, Christina, Wei, Yi, Ochoa, Francisca, Schmahl, Jennifer, Tang, Yajun, Siao, Chia-Jen, Poueymirou, William, Espert, Jennifer, Lim, Wei Keat, Atwal, Gurinder S., Murphy, Andrew J., Sleeman, Matthew A., Hovhannisyan, Zaruhi, Haxhinasto, Sokol

Volltext

Autocorrelation-Based Technique for Automated Segmentation of Endocardial Border in 3D Echocardiograms von Morda, Louis S., Lim, Wei Keat, Konofagou, Elisa E.

Volltext

Dual blockade of IL‐4 and IL‐13 with dupilumab, an IL‐4Rα antibody, is required to broadly inhibit type 2 inflammation von Le Floc’h, Audrey, Allinne, Jeanne, Nagashima, Kirsten, Scott, George, Birchard, Dylan, Asrat, Seblewongel, Bai, Yu, Lim, Wei Keat, Martin, Joel, Huang, Tammy, Potocky, Terra B., Kim, Jee H., Rafique, Ashique, Papadopoulos, Nicholas J., Stahl, Neil, Yancopoulos, George D., Murphy, Andrew J., Sleeman, Matthew A., Orengo, Jamie M.

Volltext

Dupilumab in Adults and Adolescents with Eosinophilic Esophagitis von Dellon, Evan S., Rothenberg, Marc E., Collins, Margaret H., Hirano, Ikuo, Chehade, Mirna, Bredenoord, Albert J., Lucendo, Alfredo J., Spergel, Jonathan M., Aceves, Seema, Sun, Xian, Kosloski, Matthew P., Kamal, Mohamed A., Hamilton, Jennifer D., Beazley, Bethany, McCann, Eilish, Patel, Kiran, Mannent, Leda P., Laws, Elizabeth, Akinlade, Bolanle, Amin, Nikhil, Lim, Wei Keat, Wipperman, Matthew F., Ruddy, Marcella, Patel, Naimish, Weinreich, David R., Yancopoulos, George D., Shumel, Brad, Maloney, Jennifer, Giannelou, Angeliki, Shabbir, Arsalan

Volltext

Assembling cell context-specific gene sets: a case in cardiomyopathy von Liu, Mingming, King, Vanessa, Lim, Wei Keat

Volltext

Mutations of multiple genes cause deregulation of NF- B in diffuse large B-cell lymphoma von Pasqualucci, Laura, Compagno, Mara, Lim, Wei Keat, Grunn, Adina, Nandula, Subhadra V, Brahmachary, Manisha, Shen, Qiong, Bertoni, Francesco, Ponzoni, Maurilio, Scandurra, Marta, Califano, Andrea, Bhagat, Govind, Chadburn, Amy, Dalla-Favera, Riccardo

Volltext