Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study von Hozawa, Atsushi, Tanno, Kozo, Nakaya, Naoki, Nakamura, Tomohiro, Tsuchiya, Naho, Hirata, Takumi, Narita, Akira, Kogure, Mana, Nochioka, Kotaro, Sasaki, Ryohei, Takanashi, Nobuyuki, Otsuka, Kotaro, Sakata, Kiyomi, Kuriyama, Shinichi, Kikuya, Masahiro, Tanabe, Osamu, Sugawara, Junichi, Suzuki, Kichiya, Suzuki, Yoichi, Kodama, Eiichi N., Fuse, Nobuo, Kiyomoto, Hideyasu, Tomita, Hiroaki, Uruno, Akira, Hamanaka, Yohei, Metoki, Hirohito, Ishikuro, Mami, Obara, Taku, Kobayashi, Tomoko, Kitatani, Kazuyuki, Takai-Igarashi, Takako, Ogishima, Soichi, Satoh, Mamoru, Ohmomo, Hideki, Tsuboi, Akito, Egawa, Shinichi, Ishii, Tadashi, Ito, Kiyoshi, Ito, Sadayoshi, Taki, Yasuyuki, Minegishi, Naoko, Ishii, Naoto, Nagasaki, Masao, Igarashi, Kazuhiko, Koshiba, Seizo, Shimizu, Ritsuko, Tamiya, Gen, Nakayama, Keiko, Motohashi, Hozumi, Yasuda, Jun, Shimizu, Atsushi, Hachiya, Tsuyoshi, Shiwa, Yuh, Tominaga, Teiji, Tanaka, Hiroshi, Oyama, Kotaro, Tanaka, Ryoichi, Kawame, Hiroshi, Fukushima, Akimune, Ishigaki, Yasushi, Tokutomi, Tomoharu, Osumi, Noriko, Kobayashi, Tadao, Nagami, Fuji, Hashizume, Hiroaki, Arai, Tomohiko, Kawaguchi, Yoshio, Higuchi, Shinichi, Sakaida, Masaki, Endo, Ryujin, Nishizuka, Satoshi, Tsuji, Ichiro, Hitomi, Jiro, Nakamura, Motoyuki, Ogasawara, Kuniaki, Yaegashi, Nobuo, Kinoshita, Kengo, Kure, Shigeo, Sakai, Akio, Kobayashi, Seiichiro, Sobue, Kenji, Sasaki, Makoto, Yamamoto, Masayuki

Volltext

Local IL-10 replacement therapy was effective for steroid-insensitive asthma in mice von Matsuda, Masaya, Inaba, Miki, Hamaguchi, Junpei, Tomita, Hiro, Omori, Miyu, Shimora, Hayato, Sakae, Harumi, Kitatani, Kazuyuki, Nabe, Takeshi

Volltext

Adoptive transfer of type 1 regulatory T cells suppressed the development of airway hyperresponsiveness in ovalbumin-induced airway inflammation model mice von Matsuda, Masaya, Doi, Kana, Tsutsumi, Tatsuya, Inaba, Miki, Hamaguchi, Junpei, Terada, Tetsuya, Kawata, Ryo, Kitatani, Kazuyuki, Nabe, Takeshi

Volltext

Extracellular Vesicles Derived from Allergen Immunotherapy-Treated Mice Suppressed IL-5 Production from Group 2 Innate Lymphoid Cells von Matsuda, Masaya, Shimizu, Seito, Kitatani, Kazuyuki, Nabe, Takeshi

Volltext

Sublingual immunotherapy for 4 years increased the number of Foxp3+ Treg cells, which correlated with clinical effects von Terada, Tetsuya, Matsuda, Masaya, Inaba, Miki, Hamaguchi, Junpei, Takemoto, Naoki, Kikuoka, Yusuke, Inaka, Yuko, Sakae, Harumi, Hashimoto, Kennosuke, Shimora, Hayato, Kitatani, Kazuyuki, Kawata, Ryo, Nabe, Takeshi

Volltext

Regulation of Necroptosis by Phospholipids and Sphingolipids von Zhang, Xuewei, Matsuda, Masaya, Yaegashi, Nobuo, Nabe, Takeshi, Kitatani, Kazuyuki

Volltext

Network Analysis of a Comprehensive Knowledge Repository Reveals a Dual Role for Ceramide in Alzheimer's Disease von Mizuno, Satoshi, Ogishima, Soichi, Kitatani, Kazuyuki, Kikuchi, Masataka, Tanaka, Hiroshi, Yaegashi, Nobuo, Nakaya, Jun

Volltext

Selective knockdown of ceramide synthases reveals complex interregulation of sphingolipid metabolism[S] von Mullen, Thomas D., Spassieva, Stefka, Jenkins, Russell W., Kitatani, Kazuyuki, Bielawski, Jacek, Hannun, Yusuf A., Obeid, Lina M.

Volltext

Exogenous S1P Exposure Potentiates Ischemic Stroke Damage That Is Reduced Possibly by Inhibiting S1P Receptor Signaling von Choi, Ji Woong, Ryu, Jong Hoon, Jeon, Sejin, Han, Jeong Eun, Moon, Eunjung, Chun, Jerold

Volltext

Tyrosine kinase receptor TIE-1 mediates platinum resistance by promoting nucleotide excision repair in ovarian cancer von Ishibashi, Masumi, Toyoshima, Masafumi, Zhang, Xuewei, Hasegawa-Minato, Junko, Shigeta, Shogo, Usui, Toshinori, Kemp, Christopher J., Grandori, Carla, Kitatani, Kazuyuki, Yaegashi, Nobuo

Volltext

Sphingolipids in Inflammation: From Bench to Bedside von Kitatani, Kazuyuki, Iwabuchi, Kazuhisa, Snider, Ashley, Riboni, Laura

Volltext

Regulation of Cell Migration by Sphingomyelin Synthases: Sphingomyelin in Lipid Rafts Decreases Responsiveness to Signaling by the CXCL12/CXCR4 Pathway von Asano, Satoshi, Kitatani, Kazuyuki, Taniguchi, Makoto, Hashimoto, Mayumi, Zama, Kota, Mitsutake, Susumu, Igarashi, Yasuyuki, Takeya, Hiroyuki, Kigawa, Junzo, Hayashi, Akira, Umehara, Hisanori, Okazaki, Toshiro

Volltext

Sphingomyelin Synthase 1-generated Sphingomyelin Plays an Important Role in Transferrin Trafficking and Cell Proliferation von Shakor, Abo Bakr Abdel, Taniguchi, Makoto, Kitatani, Kazuyuki, Hashimoto, Mayumi, Asano, Satoshi, Hayashi, Akira, Nomura, Kenichi, Bielawski, Jacek, Bielawska, Alicja, Watanabe, Ken, Kobayashi, Toshihide, Igarashi, Yasuyuki, Umehara, Hisanori, Takeya, Hiroyuki, Okazaki, Toshiro

Volltext

Loss of sphingosine kinase-1 activates the intrinsic pathway of programmed cell death: modulation of sphingolipid levels and the induction of apoptosis von Taha, Tarek A, Kitatani, Kazuyuki, El-Alwani, Mazen, Bielawski, Jacek, Hannun, Yusuf A, Obeid, Lina M

Volltext

Novel cooperative pathway of c-Myc and Furin, a pro-protein convertase, in cell proliferation as a therapeutic target in ovarian cancers von Hasegawa-Minato, Junko, Toyoshima, Masafumi, Ishibashi, Masumi, Zhang, Xuewei, Shigeta, Shogo, Grandori, Carla, Kitatani, Kazuyuki, Yaegashi, Nobuo

Volltext

Defining a Role for Acid Sphingomyelinase in the p38/Interleukin-6 Pathway von Perry, David M., Newcomb, Benjamin, Adada, Mohamad, Wu, Bill X., Roddy, Patrick, Kitatani, Kazuyuki, Siskind, Leah, Obeid, Lina M., Hannun, Yusuf A.

Volltext

Fasudil improves the endothelial dysfunction in the aorta of spontaneously hypertensive rats von Tsounapi, Panagiota, Saito, Motoaki, Kitatani, Kazuyuki, Dimitriadis, Fotios, Ohmasa, Fumiya, Shimizu, Shogo, Kinoshita, Yukako, Takenaka, Atsushi, Satoh, Keisuke

Volltext

The Coordination of Prostaglandin E2 Production by Sphingosine-1-phosphate and Ceramide-1-phosphate von Pettus, Benjamin J, Kitatani, Kazuyuki, Chalfant, Charles E, Taha, Tarek A, Kawamori, Toshihiko, Bielawski, Jacek, Obeid, Lina M, Hannun, Yusuf A

Volltext

Involvement of small extracellular vesicle-derived TIE-1 in the chemoresistance of ovarian cancer cells von Misawa, Tomoka, Toyoshima, Masafumi, Kitatani, Kazuyuki, Ishibashi, Masumi, Hasegawa-Minato, Junko, Shigeta, Shogo, Yaegashi, Nobuo

Volltext

Inhibitory effects of dietary glucosylceramides on squamous cell carcinoma of the head and neck in NOD/SCID mice von Fujiwara, Kazunori, Kitatani, Kazuyuki, Fukushima, Kei, Yazama, Hiroaki, Umehara, Hisanori, Kikuchi, Mitsunori, Igarashi, Yasuyuki, Kitano, Hiroya, Okazaki, Toshiro

Volltext