Attempts to understand the mechanisms of mitochondrial diseases: The reverse genetics of mouse models for mitochondrial disease von Ishikawa, Kaori, Nakada, Kazuto

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Accumulation of mitochondrial DNA with a point mutation in tRNALeu(UUR) gene induces brain dysfunction in mice von Ishikawa, Kaori, Miyata, Daiki, Hattori, Satoko, Tani, Haruna, Kuriyama, Takayoshi, Wei, Fan-Yan, Miyakawa, Tsuyoshi, Nakada, Kazuto

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Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells von Inami, Yoshihiro, Waguri, Satoshi, Sakamoto, Ayako, Kouno, Tsuguka, Nakada, Kazuto, Hino, Okio, Watanabe, Sumio, Ando, Jin, Iwadate, Manabu, Yamamoto, Masayuki, Lee, Myung-Shik, Tanaka, Keiji, Komatsu, Masaaki

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Distal control of mitochondrial biogenesis and respiratory activity by extracellular lactate caused by large-scale deletion of mitochondrial DNA von Ogasawara, Emi, Nakada, Kazuto, Ishihara, Naotada

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RLR-mediated antiviral innate immunity requires oxidative phosphorylation activity von Yoshizumi, Takuma, Imamura, Hiromi, Taku, Tomohiro, Kuroki, Takahiro, Kawaguchi, Atsushi, Ishikawa, Kaori, Nakada, Kazuto, Koshiba, Takumi

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ROS-Generating Mitochondrial DNA Mutations Can Regulate Tumor Cell Metastasis von Ishikawa, Kaori, Takenaga, Keizo, Akimoto, Miho, Koshikawa, Nobuko, Yamaguchi, Aya, Imanishi, Hirotake, Nakada, Kazuto, Honma, Yoshio, Hayashi, Jun-Ichi

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Dynamics of Mitochondrial DNA Nucleoids Regulated by Mitochondrial Fission Is Essential for Maintenance of Homogeneously Active Mitochondria during Neonatal Heart Development von Ishihara, Takaya, Ban-Ishihara, Reiko, Maeda, Maki, Matsunaga, Yui, Ichimura, Ayaka, Kyogoku, Sachiko, Aoki, Hiroki, Katada, Shun, Nakada, Kazuto, Nomura, Masatoshi, Mizushima, Noboru, Mihara, Katsuyoshi, Ishihara, Naotada

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Mitochondrial DNA mutations regulate metastasis of human breast cancer cells von Imanishi, Hirotake, Hattori, Keisuke, Wada, Reiko, Ishikawa, Kaori, Fukuda, Sayaka, Takenaga, Keizo, Nakada, Kazuto, Hayashi, Jun-ichi

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A high mutation load of m.14597A>G in MT-ND6 causes Leigh syndrome von Kishita, Yoshihito, Ishikawa, Kaori, Nakada, Kazuto, Hayashi, Jun-Ichi, Fushimi, Takuya, Shimura, Masaru, Kohda, Masakazu, Ohtake, Akira, Murayama, Kei, Okazaki, Yasushi

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Aberrant RNA processing contributes to the pathogenesis of mitochondrial diseases in trans-mitochondrial mouse model carrying mitochondrial tRNALeu(UUR) with a pathogenic A2748G mu... von Tani, Haruna, Ishikawa, Kaori, Tamashiro, Hiroaki, Ogasawara, Emi, Yasukawa, Takehiro, Matsuda, Shigeru, Shimizu, Akinori, Kang, Dongchon, Hayashi, Jun-Ichi, Wei, Fan-Yan, Nakada, Kazuto

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Mitochondrial DNA mutations are involved in the acquisition of cisplatin resistance in human lung cancer A549 cells von Horibe, Sayo, Ishikawa, Kaori, Nakada, Kazuto, Wake, Masaki, Takeda, Norihiko, Tanaka, Toru, Kawauchi, Shoji, Sasaki, Naoto, Rikitake, Yoshiyuki

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TFB2M and POLRMT are essential for mammalian mitochondrial DNA replication von Inatomi, Teppei, Matsuda, Shigeru, Ishiuchi, Takashi, Do, Yura, Nakayama, Masunari, Abe, Shusaku, Kasho, Kazutoshi, Wanrooij, Sjoerd, Nakada, Kazuto, Ichiyanagi, Kenji, Sasaki, Hiroyuki, Yasukawa, Takehiro, Kang, Dongchon

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Concentration of mitochondrial DNA mutations by cytoplasmic transfer from platelets to cultured mouse cells von Ishikawa, Kaori, Kobayashi, Kohei, Yamada, Akihito, Umehara, Moe, Oka, Toshihiko, Nakada, Kazuto

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Specific mitochondrial DNA mutation in mice regulates diabetes and lymphoma development von Hashizume, Osamu, Shimizu, Akinori, Yokota, Mutsumi, Sugiyama, Atsuko, Nakada, Kazuto, Miyoshi, Hiroyuki, Itami, Makiko, Ohira, Miki, Nagase, Hiroki, Takenaga, Keizo, Hayashi, Jun-Ichi

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Epigenetic regulation of the nuclear-coded GCAT and SHMT2 genes confers human age-associated mitochondrial respiration defects von Hashizume, Osamu, Ohnishi, Sakiko, Mito, Takayuki, Shimizu, Akinori, Ishikawa, Kaori, Nakada, Kazuto, Soda, Manabu, Mano, Hiroyuki, Togayachi, Sumie, Miyoshi, Hiroyuki, Okita, Keisuke, Hayashi, Jun-Ichi

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Acquired Expression of Mutant Mitofusin 2 Causes Progressive Neurodegeneration and Abnormal Behavior von Ishikawa, Kaori, Yamamoto, Satoshi, Hattori, Satoko, Nishimura, Naoya, Tani, Haruna, Mito, Takayuki, Matsumoto, Hirokazu, Miyakawa, Tsuyoshi, Nakada, Kazuto

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Mitochonic Acid 5 Binds Mitochondria and Ameliorates Renal Tubular and Cardiac Myocyte Damage von Suzuki, Takehiro, Yamaguchi, Hiroaki, Kikusato, Motoi, Hashizume, Osamu, Nagatoishi, Satoru, Matsuo, Akihiro, Sato, Takeya, Kudo, Tai, Matsuhashi, Tetsuro, Murayama, Kazutaka, Ohba, Yuki, Watanabe, Shun, Kanno, Shin-Ichiro, Minaki, Daichi, Saigusa, Daisuke, Shinbo, Hiroko, Mori, Nobuyoshi, Yuri, Akinori, Yokoro, Miyuki, Mishima, Eikan, Shima, Hisato, Akiyama, Yasutoshi, Takeuchi, Yoichi, Kikuchi, Koichi, Toyohara, Takafumi, Suzuki, Chitose, Ichimura, Takaharu, Anzai, Jun-Ichi, Kohzuki, Masahiro, Mano, Nariyasu, Kure, Shigeo, Yanagisawa, Teruyuki, Tomioka, Yoshihisa, Toyomizu, Masaaki, Tsumoto, Kohei, Nakada, Kazuto, Bonventre, Joseph V, Ito, Sadayoshi, Osaka, Hitoshi, Hayashi, Ken-Ichi, Abe, Takaaki

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Transmitochondrial mice as models for primary prevention of diseases caused by mutation in the tRNA(Lys) gene von Shimizu, Akinori, Mito, Takayuki, Hayashi, Chisato, Ogasawara, Emi, Koba, Ryusuke, Negishi, Issei, Takenaga, Keizo, Nakada, Kazuto, Hayashi, Jun-Ichi

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Disruption of the mouse Shmt2 gene confers embryonic anaemia via foetal liver-specific metabolomic disorders von Tani, Haruna, Mito, Takayuki, Velagapudi, Vidya, Ishikawa, Kaori, Umehara, Moe, Nakada, Kazuto, Suomalainen, Anu, Hayashi, Jun-Ichi

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Mitochondria-Related Male Infertility von Nakada, Kazuto, Sato, Akitsugu, Yoshida, Kayo, Morita, Takashi, Tanaka, Hiromitsu, Inoue, Shin-Ichi, Yonekawa, Hiromichi, Hayashi, Jun-Ichi

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