FMS-like Tyrosine Kinase 3/FLT3: From Basic Science to Clinical Implications von Kazi, Julhash U, Rönnstrand, Lars

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T cell receptor (TCR) signaling in health and disease von Shah, Kinjal, Al-Haidari, Amr, Sun, Jianmin, Kazi, Julhash U.

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Phosphorylation-Dependent Regulation of WNT/Beta-Catenin Signaling von Shah, Kinjal, Kazi, Julhash U

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Machine learning in the prediction of cancer therapy von Rafique, Raihan, Islam, S.M. Riazul, Kazi, Julhash U.

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Src-Like adaptor protein (SLAP) binds to the receptor tyrosine kinase Flt3 and modulates receptor stability and downstream signaling von Kazi, Julhash U, Rönnstrand, Lars

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Discovery of a small molecule that inhibits Bcl-3-mediated cyclin D1 expression in melanoma cells von Saamarthy, Karunakar, Ahlqvist, Kristofer, Daams, Renée, Balagunaseelan, Navisraj, Rinaldo-Matthis, Agnes, Kazi, Julhash U, Sime, Wondossen, Massoumi, Ramin

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SYK Is a Critical Regulator of FLT3 in Acute Myeloid Leukemia von Puissant, Alexandre, Fenouille, Nina, Alexe, Gabriela, Pikman, Yana, Bassil, Christopher F., Mehta, Swapnil, Du, Jinyan, Kazi, Julhash U., Luciano, Frédéric, Rönnstrand, Lars, Kung, Andrew L., Aster, Jon C., Galinsky, Ilene, Stone, Richard M., DeAngelo, Daniel J., Hemann, Michael T., Stegmaier, Kimberly

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Enhancing cell death in B-cell malignancies through targeted inhibition of Bcl-3 von Daams, Renée, Tran, Thi Thu Phuong, Jemaà, Mohamed, Sime, Wondossen, Mickeviciute, Ruta, Ek, Sara, Rönnstrand, Lars, Kazi, Julhash U., Massoumi, Ramin

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A deep tabular data learning model predicting cisplatin sensitivity identifies BCL2L1 dependency in cancer von Nasimian, Ahmad, Ahmed, Mehreen, Hedenfalk, Ingrid, Kazi, Julhash U.

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Phosphorylation of the Activation Loop Tyrosine 823 in c-Kit Is Crucial for Cell Survival and Proliferation von Agarwal, Shruti, Kazi, Julhash U., Rönnstrand, Lars

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Xputer: bridging data gaps with NMF, XGBoost, and a streamlined GUI experience von Younus, Saleena, Rönnstrand, Lars, Kazi, Julhash U

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Suppressor of Cytokine Signaling 6 (SOCS6) Negatively Regulates Flt3 Signal Transduction through Direct Binding to Phosphorylated Tyrosines 591 and 919 of Flt3 von Kazi, Julhash U., Sun, Jianmin, Phung, Bengt, Zadjali, Fahad, Flores-Morales, Amilcar, Rönnstrand, Lars

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De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia von Hyrenius-Wittsten, Axel, Pilheden, Mattias, Sturesson, Helena, Hansson, Jenny, Walsh, Michael P., Song, Guangchun, Kazi, Julhash U., Liu, Jian, Ramakrishan, Ramprasad, Garcia-Ruiz, Cristian, Nance, Stephanie, Gupta, Pankaj, Zhang, Jinghui, Rönnstrand, Lars, Hultquist, Anne, Downing, James R., Lindkvist-Petersson, Karin, Paulsson, Kajsa, Järås, Marcus, Gruber, Tanja A., Ma, Jing, Hagström-Andersson, Anna K.

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Germline mutations of KIT in gastrointestinal stromal tumor (GIST) and mastocytosis von Ke, Hengning, Kazi, Julhash U, Zhao, Hui, Sun, Jianmin

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The role of HOXB2 and HOXB3 in acute myeloid leukemia von Lindblad, Oscar, Chougule, Rohit A., Moharram, Sausan A., Kabir, Nuzhat N., Sun, Jianmin, Kazi, Julhash U., Rönnstrand, Lars

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The Aurora kinase/β-catenin axis contributes to dexamethasone resistance in leukemia von Shah, Kinjal, Ahmed, Mehreen, Kazi, Julhash U.

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Mechanisms of Anticancer Therapy Resistance: The Role of Cancer Stem Cells von Kazi, Julhash U

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FLT3 signals via the adapter protein Grb10 and overexpression of Grb10 leads to aberrant cell proliferation in acute myeloid leukemia von Kazi, Julhash U., Rönnstrand, Lars

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The role of SRC family kinases in FLT3 signaling von Kazi, Julhash U., Rönnstrand, Lars

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PLK1 as a cooperating partner for BCL2-mediated antiapoptotic program in leukemia von Shah, Kinjal, Nasimian, Ahmad, Ahmed, Mehreen, Al Ashiri, Lina, Denison, Linn, Sime, Wondossen, Bendak, Katerina, Kolosenko, Iryna, Siino, Valentina, Levander, Fredrik, Palm-Apergi, Caroline, Massoumi, Ramin, Lock, Richard B., Kazi, Julhash U.

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