Know thy cells: commonly used triple-negative human breast cancer cell lines carry mutations in RAS and effectors von Wagner, Kay-Uwe

Volltext

Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets von Witkiewicz, Agnieszka K., McMillan, Elizabeth A., Balaji, Uthra, Baek, GuemHee, Lin, Wan-Chi, Mansour, John, Mollaee, Mehri, Wagner, Kay-Uwe, Koduru, Prasad, Yopp, Adam, Choti, Michael A., Yeo, Charles J., McCue, Peter, White, Michael A., Knudsen, Erik S.

Volltext

Momelotinib inhibits ACVR1/ALK2, decreases hepcidin production, and ameliorates anemia of chronic disease in rodents von Asshoff, Malte, Petzer, Verena, Warr, Matthew R., Haschka, David, Tymoszuk, Piotr, Demetz, Egon, Seifert, Markus, Posch, Wilfried, Nairz, Manfred, Maciejewski, Pat, Fowles, Peter, Burns, Christopher J., Smith, Gregg, Wagner, Kay-Uwe, Weiss, Guenter, Whitney, J.Andrew, Theurl, Igor

Volltext

Critical Role of Jak2 in the Maintenance and Function of Adult Hematopoietic Stem Cells von Akada, Hajime, Akada, Saeko, Hutchison, Robert E., Sakamoto, Kazuhito, Wagner, Kay‐Uwe, Mohi, Golam

Volltext

Crosstalk between STAT5 activation and PI3K/AKT functions in normal and transformed mammary epithelial cells von Rädler, Patrick D., Wehde, Barbara L., Wagner, Kay-Uwe

Volltext

Highly metastatic claudin-low mammary cancers can originate from luminal epithelial cells von Rädler, Patrick D., Wehde, Barbara L., Triplett, Aleata A., Shrestha, Hridaya, Shepherd, Jonathan H., Pfefferle, Adam D., Rui, Hallgeir, Cardiff, Robert D., Perou, Charles M., Wagner, Kay-Uwe

Volltext

Estrogen receptor-α expression in the mammary epithelium is required for ductal and alveolar morphogenesis in mice von Feng, Yuxin, Manka, David, Wagner, Kay-Uwe, Khan, Sohaib A

Volltext

Autocrine IGF1 Signaling Mediates Pancreatic Tumor Cell Dormancy in the Absence of Oncogenic Drivers von Rajbhandari, Nirakar, Lin, Wan-chi, Wehde, Barbara L., Triplett, Aleata A., Wagner, Kay-Uwe

Volltext

Janus-kinase-2 relates directly to portal hypertension and to complications in rodent and human cirrhosis von Klein, Sabine, Rick, Johanna, Lehmann, Jennifer, Schierwagen, Robert, Schierwagen, Irela Gretchen, Verbeke, Len, Hittatiya, Kanishka, Uschner, Frank Erhard, Manekeller, Steffen, Strassburg, Christian P, Wagner, Kay-Uwe, Sayeski, Peter P, Wolf, Dominik, Laleman, Wim, Sauerbruch, Tilman, Trebicka, Jonel

Volltext

Thymic stromal lymphopoietin-mediated STAT5 phosphorylation via kinases JAK1 and JAK2 reveals a key difference from IL-7–induced signaling von Rochman, Yrina, Kashyap, Mohit, Robinson, Gertraud W., Sakamoto, Kazuhito, Gomez-Rodriguez, Julio, Wagner, Kay-Uwe, Leonard, Warren J., Paul, William E.

Volltext

Janus Kinase 1 Plays a Critical Role in Mammary Cancer Progression von Wehde, Barbara L., Rädler, Patrick D., Shrestha, Hridaya, Johnson, Stevi J., Triplett, Aleata A., Wagner, Kay-Uwe

Volltext

Tumor susceptibility gene 101 is required for the maintenance of uterine epithelial cells during embryo implantation von Byun, Hyunji, Kwon, Sojung, Wagner, Kay-Uwe, Shin, Hyejin, Lim, Hyunjung Jade

Volltext

Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice von Mueller, Kristina M., Kornfeld, Jan‐Wilhelm, Friedbichler, Katrin, Blaas, Leander, Egger, Gerda, Esterbauer, Harald, Hasselblatt, Peter, Schlederer, Michaela, Haindl, Susanne, Wagner, Kay‐Uwe, Engblom, David, Haemmerle, Guenter, Kratky, Dagmar, Sexl, Veronika, Kenner, Lukas, Kozlov, Andrey V., Terracciano, Luigi, Zechner, Rudolf, Schuetz, Guenther, Casanova, Emilio, Pospisilik, J. Andrew, Heim, Markus H., Moriggl, Richard

Volltext

Peripubertal requirement of Tsg101 in maintaining the integrity of membranous structures in mouse oocytes von Shin, Hyejin, Park, Dayoung, Kim, Jiyeon, Nam, Min‐Yeong, Kwon, Sojung, Um, Da‐Eun, Oh, Ji‐Eun, Youn, Esther, Shim, Yhong‐Hee, Wagner, Kay‐Uwe, Jun, Jin Hyun, Kim, Hye‐Ryun, Song, Haengseok, Lim, Hyunjung Jade

Volltext

Stat5 Regulates the Phosphatidylinositol 3-Kinase/Akt1 Pathway during Mammary Gland Development and Tumorigenesis von Schmidt, Jeffrey W., Wehde, Barbara L., Sakamoto, Kazuhito, Triplett, Aleata A., Anderson, Steven M., Tsichlis, Philip N., Leone, Gustavo, Wagner, Kay-Uwe

Volltext

The Janus kinase 1 is critical for pancreatic cancer initiation and progression von Shrestha, Hridaya, Rädler, Patrick D., Dennaoui, Rayane, Wicker, Madison N., Rajbhandari, Nirakar, Sun, Yunguang, Peck, Amy R., Vistisen, Kerry, Triplett, Aleata A., Beydoun, Rafic, Sterneck, Esta, Saur, Dieter, Rui, Hallgeir, Wagner, Kay-Uwe

Volltext

Dual recombinase action in the normal and neoplastic mammary gland epithelium von Rädler, Patrick D., Vistisen, Kerry, Triplett, Aleata A., Dennaoui, Rayane, Li, Yong, Shrestha, Hridaya, Ferraiuolo, Rosa-Maria, Thangasamy, Amalraj, Saur, Dieter, Wagner, Kay-Uwe

Volltext

The Multifaceted Roles of the Tumor Susceptibility Gene 101 (TSG101) in Normal Development and Disease von Ferraiuolo, Rosa-Maria, Manthey, Karoline C, Stanton, Marissa J, Triplett, Aleata A, Wagner, Kay-Uwe

Volltext

Macrophage JAK2 deficiency protects against high-fat diet-induced inflammation von Desai, Harsh R., Sivasubramaniyam, Tharini, Revelo, Xavier S., Schroer, Stephanie A., Luk, Cynthia T., Rikkala, Prashanth R., Metherel, Adam H., Dodington, David W., Park, Yoo Jin, Kim, Min Jeong, Rapps, Joshua A., Besla, Rickvinder, Robbins, Clinton S., Wagner, Kay-Uwe, Bazinet, Richard P., Winer, Daniel A., Woo, Minna

Volltext

G-protein-coupled Receptor Agonist BV8/Prokineticin-2 and STAT3 Protein Form a Feed-forward Loop in Both Normal and Malignant Myeloid Cells von Xin, Hong, Lu, Rongze, Lee, Heehyoung, Zhang, Wang, Zhang, Chunyan, Deng, Jiehui, Liu, Yong, Shen, Shudan, Wagner, Kay-Uwe, Forman, Stephen, Jove, Richard, Yu, Hua

Volltext