A proteome-wide atlas of lysine-reactive chemistry von Abbasov, Mikail E., Kavanagh, Madeline E., Ichu, Taka-Aki, Lazear, Michael R., Tao, Yongfeng, Crowley, Vincent M., am Ende, Christopher W., Hacker, Stephan M., Ho, Jordan, Dix, Melissa M., Suciu, Radu, Hayward, Matthew M., Kiessling, Laura L., Cravatt, Benjamin F.

Volltext

Selective inhibitors of JAK1 targeting an isoform-restricted allosteric cysteine von Kavanagh, Madeline E., Horning, Benjamin D., Khattri, Roli, Roy, Nilotpal, Lu, Justine P., Whitby, Landon R., Ye, Elva, Brannon, Jaclyn C., Parker, Albert, Chick, Joel M., Eissler, Christie L., Wong, Ashley J., Rodriguez, Joe L., Rodiles, Socorro, Masuda, Kim, Teijaro, John R., Simon, Gabriel M., Patricelli, Matthew P., Cravatt, Benjamin F.

Volltext

The development of CNS-active LRRK2 inhibitors using property-directed optimisation von Kavanagh, Madeline E., Doddareddy, Munikumar Reddy, Kassiou, Michael

Volltext

Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis von Katariya, Mona M., Snee, Matthew, Tunnicliffe, Richard B., Kavanagh, Madeline E., Boshoff, Helena I. M., Amadi, Cecilia N., Levy, Colin W., Munro, Andrew W., Abell, Chris, Leys, David, Coyne, Anthony G., McLean, Kirsty J.

Volltext

Effect of DMSO on Protein Structure and Interactions Assessed by Collision-Induced Dissociation and Unfolding von Chan, Daniel S.-H, Kavanagh, Madeline E, McLean, Kirsty J, Munro, Andrew. W, Matak-Vinković, Dijana, Coyne, Anthony G, Abell, Chris

Volltext

Structural characterization of CYP144A1 – a cytochrome P450 enzyme expressed from alternative transcripts in Mycobacterium tuberculosis von Chenge, Jude, Kavanagh, Madeline E., Driscoll, Max D., McLean, Kirsty J., Young, Douglas B., Cortes, Teresa, Matak-Vinkovic, Dijana, Levy, Colin W., Rigby, Stephen E. J., Leys, David, Abell, Chris, Munro, Andrew W.

Volltext

Fragment-Based Approaches to the Development of Mycobacterium tuberculosis CYP121 Inhibitors von Kavanagh, Madeline E, Coyne, Anthony G, McLean, Kirsty J, James, Guy G, Levy, Colin W, Marino, Leonardo B, de Carvalho, Luiz Pedro S, Chan, Daniel S. H, Hudson, Sean A, Surade, Sachin, Leys, David, Munro, Andrew W, Abell, Chris

Volltext

A new strategy for hit generation: Novel in cellulo active inhibitors of CYP121A1 from Mycobacterium tuberculosis via a combined X-ray crystallographic and phenotypic screening app... von Frederickson, Martyn, Selvam, Irwin R., Evangelopoulos, Dimitrios, McLean, Kirsty J., Katariya, Mona M., Tunnicliffe, Richard B., Campbell, Bethany, Kavanagh, Madeline E., Charoensutthivarakul, Sitthivut, Blankley, Richard T., Levy, Colin W., de Carvalho, Luiz Pedro S., Leys, David, Munro, Andrew W., Coyne, Anthony G., Abell, Chris

Volltext

Spirooxindoles as novel 3D-fragment scaffolds: Synthesis and screening against CYP121 from M. tuberculosis von Davis, Holly J., Kavanagh, Madeline E., Balan, Tudor, Abell, Chris, Coyne, Anthony G.

Volltext

Glutathione synthesis in the mouse liver supports lipid abundance through NRF2 repression von Asantewaa, Gloria, Tuttle, Emily T., Ward, Nathan P., Kang, Yun Pyo, Kim, Yumi, Kavanagh, Madeline E., Girnius, Nomeda, Chen, Ying, Rodriguez, Katherine, Hecht, Fabio, Zocchi, Marco, Smorodintsev-Schiller, Leonid, Scales, TashJaé Q., Taylor, Kira, Alimohammadi, Fatemeh, Duncan, Renae P., Sechrist, Zachary R., Agostini-Vulaj, Diana, Schafer, Xenia L., Chang, Hayley, Smith, Zachary R., O’Connor, Thomas N., Whelan, Sarah, Selfors, Laura M., Crowdis, Jett, Gray, G. Kenneth, Bronson, Roderick T., Brenner, Dirk, Rufini, Alessandro, Dirksen, Robert T., Hezel, Aram F., Huber, Aaron R., Munger, Joshua, Cravatt, Benjamin F., Vasiliou, Vasilis, Cole, Calvin L., DeNicola, Gina M., Harris, Isaac S.

Volltext

Author Correction: Selective inhibitors of JAK1 targeting an isoform-restricted allosteric cysteine von Kavanagh, Madeline E., Horning, Benjamin D., Khattri, Roli, Roy, Nilotpal, Lu, Justine P., Whitby, Landon R., Ye, Elva, Brannon, Jaclyn C., Parker, Albert, Chick, Joel M., Eissler, Christie L., Wong, Ashley J., Rodriguez, Joe L., Rodiles, Socorro, Masuda, Kim, Teijaro, John R., Simon, Gabriel M., Patricelli, Matthew P., Cravatt, Benjamin F.

Volltext

Publisher Correction: A proteome-wide atlas of lysine-reactive chemistry von Abbasov, Mikail E., Kavanagh, Madeline E., Ichu, Taka-Aki, Lazear, Michael R., Tao, Yongfeng, Crowley, Vincent M., am Ende, Christopher W., Hacker, Stephan M., Ho, Jordan, Dix, Melissa M., Suciu, Radu, Hayward, Matthew M., Kiessling, Laura L., Cravatt, Benjamin F.

Volltext

Optimisation of LRRK2 inhibitors and assessment of functional efficacy in cell-based models of neuroinflammation von Munoz, Lenka, Kavanagh, Madeline E., Phoa, Athena F., Heng, Benjamin, Dzamko, Nicolas, Chen, Ew-Jun, Doddareddy, Munikumar Reddy, Guillemin, Gilles J., Kassiou, Michael

Volltext

Fragment Profiling Approach to Inhibitors of the Orphan M. tuberculosis P450 CYP144A1 von Kavanagh, Madeline E, Chenge, Jude, Zoufir, Azedine, McLean, Kirsty J, Coyne, Anthony G, Bender, Andreas, Munro, Andrew W, Abell, Chris

Volltext

Structural Characterization and Ligand/Inhibitor Identification Provide Functional Insights into the Mycobacterium tuberculosis Cytochrome P450 CYP126A1 von Chenge, Jude T., Van Duyet, Le, Swami, Shalini, McLean, Kirsty J., Kavanagh, Madeline E., Coyne, Anthony G., Rigby, Stephen E.J., Cheesman, Myles R., Girvan, Hazel M., Levy, Colin W., Rupp, Bernd, von Kries, Jens P., Abell, Chris, Leys, David, Munro, Andrew W.

Volltext

Substrate Fragmentation for the Design of M. tuberculosis CYP121 Inhibitors von Kavanagh, Madeline E., Gray, Janine L., Gilbert, Sophie H., Coyne, Anthony G., McLean, Kirsty J., Davis, Holly J., Munro, Andrew W., Abell, Chris

Volltext

Substrate Fragmentation for the Design of M.tuberculosis CYP121 Inhibitors von Kavanagh, Madeline E, Gray, Janine L, Gilbert, Sophie H, Coyne, Anthony G, McLean, Kirsty J, Davis, Holly J, Munro, Andrew W, Abell, Chris

Volltext

Corrigendum: Substrate Fragmentation for the Design of M. tuberculosis CYP121 Inhibitors von Kavanagh, Madeline E., Gray, Janine L., Gilbert, Sophie H., Coyne, Anthony G., McLean, Kirsty J., Davis, Holly J., Munro, Andrew W., Abell, Chris

Volltext

Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors von Brem, Jürgen, Panduwawala, Tharindi, Hansen, Jon Ulf, Hewitt, Joanne, Liepins, Edgars, Donets, Pawel, Espina, Laura, Farley, Alistair J. M., Shubin, Kirill, Campillos, Gonzalo Gomez, Kiuru, Paula, Shishodia, Shifali, Krahn, Daniel, Leśniak, Robert K., Schmidt (Adrian), Juliane, Calvopiña, Karina, Turrientes, María-Carmen, Kavanagh, Madeline E., Lubriks, Dmitrijs, Hinchliffe, Philip, Langley, Gareth W., Aboklaish, Ali F., Eneroth, Anders, Backlund, Maria, Baran, Andrei G., Nielsen, Elisabet I., Speake, Michael, Kuka, Janis, Robinson, John, Grinberga, Solveiga, Robinson, Lindsay, McDonough, Michael A., Rydzik, Anna M., Leissing, Thomas M., Jimenez-Castellanos, Juan Carlos, Avison, Matthew B., Da Silva Pinto, Solange, Pannifer, Andrew D., Martjuga, Marina, Widlake, Emma, Priede, Martins, Hopkins Navratilova, Iva, Gniadkowski, Marek, Belfrage, Anna Karin, Brandt, Peter, Yli-Kauhaluoma, Jari, Bacque, Eric, Page, Malcolm G. P., Björkling, Fredrik, Tyrrell, Jonathan M., Spencer, James, Lang, Pauline A., Baranczewski, Pawel, Cantón, Rafael, McElroy, Stuart P., Jones, Philip S., Baquero, Fernando, Suna, Edgars, Morrison, Angus, Walsh, Timothy R., Schofield, Christopher J.

Volltext

Australian consumer perception of non-alcoholic beer, white wine, red wine, and spirits von Day, Irma, Deroover, Kristine, Kavanagh, Madeline, Beckett, Emma, Akanbi, Taiwo, Pirinen, Melanie, Bucher, Tamara

Volltext