Total Synthesis of Norhalichondrin B von Jackson, Katrina L, Henderson, James A, Motoyoshi, Hajime, Phillips, Andrew J

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Highly Functionalized Pyranopyrans from Furans:  A Synthesis of the C27−C38 and C44−C53 Subunits of Norhalichondrin B von Henderson, James A, Jackson, Katrina L, Phillips, Andrew J

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Synthesis and Structure of Two New Mycolactones Isolated from M. ulcerans subsp. shinshuense von Hande, Sudhir M, Kazumi, Yuko, Lai, W. George, Jackson, Katrina L, Maeda, Shinji, Kishi, Yoshito

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The Halichondrins and E7389 von Jackson, Katrina L, Henderson, James A, Phillips, Andrew J

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Discovery of Novel, Orally Bioavailable Pyrimidine Ether-Based Inhibitors of ELOVL1 von Boyd, Michael J, Collier, Philip N, Clark, Michael P, Deng, Hongbo, Kesavan, Sarathy, Ronkin, Steven M, Waal, Nathan, Wang, Jian, Cao, Jingrong, Li, Pan, Come, Jon, Davies, Ioana, Duffy, John P, Cochran, John E, Court, John J, Chandupatla, Kishan, Jackson, Katrina L, Maltais, Francois, O’Dowd, Hardwin, Boucher, Christina, Considine, Tony, Taylor, William P, Gao, Hong, Chakilam, Ananthisrinivas, Engtrakul, Juntyma, Crawford, Dan, Doyle, Elizabeth, Phillips, Jonathan, Kemper, Raymond, Swett, Rebecca, Empfield, James, Bunnage, Mark E, Charifson, Paul S, Magavi, Sanjay Shivayogi

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Discovery and Optimization of Pyrazole Amides as Inhibitors of ELOVL1 von Come, Jon H, Senter, Timothy J, Clark, Michael P, Court, John J, Gale-Day, Zachary, Gu, Wenxin, Krueger, Elaine, Liang, Jianglin, Morris, Mark, Nanthakumar, Suganthini, O’Dowd, Hardwin, Maltais, Francois, Iyer, Ganesh, Andreassi, John, Boucher, Christina, Considine, Tony, Moody, Cameron S, Taylor, William, Mohanty, Arun K, Huang, Yulin, Zuccola, Harmon, Coll, Joyce, Bonanno, Kenneth C, Gagnon, Kevin J, Gan, Lu, Lu, Fan, Gao, Hong, Chakilam, Ananthisrinivas, Engtrakul, Juntyma, Song, Bin, Crawford, Dan, Doyle, Elisabeth, Kramer, Tal, Vought, Bryan, Phillips, Jonathan, Kemper, Raymond, Sanders, Martin, Swett, Rebecca, Furey, Brinley, Winquist, Ray, Bunnage, Mark E, Jackson, Katrina L, Charifson, Paul S, Magavi, Sanjay S

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Scalable and efficient synthesis of the mycolactone core von Jackson, Katrina L., Li, Wenju, Chen, Chi-Li, Kishi, Yoshito

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A synthesis of the C1–C15 domain of the halichondrins von Jackson, Katrina L., Henderson, James A., Morris, Jonathan C., Motoyoshi, Hajime, Phillips, Andrew J.

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Heterogeneity in the stereochemistry of mycolactones isolated from M. marinum: toxins produced by fresh vs. saltwater fish pathogens von Kim, Han-Je, Jackson, Katrina L, Kishi, Yoshito, Williamson, Heather R, Mosi, Lydia, Small, Pamela L C

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CFT8634, a Clinical Stage BRD9 Bi DAC™ Degrader, Is Active in a Subset of Multiple Myeloma Cell Line Models and Synergistic When Combined with Pomalidomide von Poling, Laura L, Cocozziello, David, He, Minsheng, Hurh, Eunju, Lobbardi, Riadh, Jackson, Katrina L, Fisher, Stewart L, Pollock, Roy M

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Abstract ND05: The discovery and characterization of CFT1946: A potent, selective, and orally bioavailable degrader of mutant BRAF for the treatment of BRAF-driven cancers von Liang, Yanke, Sowa, Mathew E., Jackson, Katrina L., Simard, Jeffrey R., Kreger, Bridget, Li, Ping, Poling, Laura, Baddour, Joelle, Good, Andrew, Huang, Hongwei, Eron, Scott, Nasveschuk, Christopher G., Yu, Robert, Fitzgerald, Mark, Garza, Victoria, O’Shea, Morgan W., Veits, Gesine, Yap, Jeremy L., Moustakim, Moses, Hart, Ashley, Agafonov, Roman V., Sarkissian, Grace, Patel, Joe S., Deibler, Richard, Cole, Kyle S., Cocozziello, David, Rahman, Fazlur, Phillips, Andrew J., Norton, Elizabeth, Crystal, Adam S., Pollock, Roy M., Fisher, Stewart L.

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Abstract 3425: The discovery and characterization of CFT1946: A potent, selective, and orally bioavailable degrader of mutant BRAF for the treatment of BRAF-driven cancers von Liang, Yanke, Sowa, Mathew E., Jackson, Katrina L., Simard, Jeffrey R., Kreger, Bridget, Li, Ping, Poling, Laura, Baddour, Joelle, Good, Andrew, Huang, Hongwei, Eron, Scott, Nasveschuk, Christopher G., Yu, Robert, Fitzgerald, Mark, Garza, Victoria, O’Shea, Morgan W., Veits, Gesine, Yap, Jeremy Y., Moustakim, Moses, Hart, Ashley, Agafonov, Roman V., Sarkissian, Grace, Patel, Joe S., Deibler, Richard, Cole, Kyle S., Cocozziello, David, Rahman, Fazlur, Phillips, Andrew J., Norton, Elizabeth, Crystal, Adam S., Pollock, Roy M., Fisher, Stewart L.

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Abstract ND09: The discovery and characterization of CFT8634: A potent and selective degrader of BRD9 for the treatment of SMARCB1-perturbed cancers von Jackson, Katrina L., Agafonov, Roman V., Carlson, Mark W., Chaturvedi, Prasoon, Cocozziello, David, Cole, Kyle, Deibler, Richard, Eron, Scott J., Good, Andrew, Hart, Ashley A., He, Minsheng, Henderson, Christina S., Huang, Hongwei, Isasa, Marta, Kirby, R. Jason, Lee, Linda, Mahler, Michelle, Moustakim, Moses, Nasveschuk, Christopher G., Palmer, Michael, Poling, Laura L., Pollock, Roy M., Schnaderbeck, Matthew, Spence, Stan, Veits, Gesine K., Yap, Jeremy L., Yin, Ning, Zeid, Rhamy, Crystal, Adam S., Phillips, Andrew J., Fisher, Stewart L.

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Abstract 2158: Preclinical evaluation of CFT1946 as a selective degrader of mutant BRAF for the treatment of BRAF driven cancers von Sowa, Mathew E., Kreger, Bridget, Baddour, Joelle, Liang, Yanke, Simard, Jeffrey R., Poling, Laura, Li, Ping, Yu, Robert, Hart, Ashley, Agafonov, Roman V., Sarkissian, Grace, Patel, Joe Sahil, Deibler, Richard, Cole, Kyle S., Eron, Scott, Cocozziello, David, Rahman, Fazlur, Moustakim, Moses, Nasveschuk, Christopher G., Jackson, Katrina L., Fitzgerald, Mark, Garza, Victoria, O’Shea, Morgan, Veits, Gesine, Yap, Jeremy L., Phillips, Andrew J., Norton, Elizabeth, Crystal, Adam S., Fisher, Stewart L., Pollock, Roy M.

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Compounds for targeted degradation of BRD9 von Yap, Jeremy L, Yin, Ning, Nasveschuk, Christopher G, Jackson, Katrina L, Veits, Gesine Kerstin, Zeid, Rhamy, Moustakim, Moses

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Compounds for targeted degradation of BRD9 von Yap, Jeremy L, Yin, Ning, Nasveschuk, Christopher G, Jackson, Katrina L, Veits, Gesine Kerstin, Zeid, Rhamy, Moustakim, Moses

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COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 von JACKSON, Katrina L, YAP, Jeremy L, VEITS, Gesine Kerstin, MOUSTAKIM, Moses, ZEID, Rhamy, NASVESCHUK, Christopher G, YIN, Ning

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COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 von Yap, Jeremy L, Yin, Ning, Nasveschuk, Christopher G, Jackson, Katrina L, Veits, Gesine Kerstin, Zeid, Rhamy, Moustakim, Moses

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A Total Synthesis of Norhalichondrin B von Jackson, Katrina L., Henderson, James A., Motoyoshi, Hajime, Phillips, Andrew J.

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TRICYCLIC HETEROBIFUNCTIONAL COMPOUNDS FOR DEGRADATION OF TARGETED PROTEINS von Henderson, James A, Anderson, Corey Don, Duplessis, Martin, Nasveschuk, Christopher G, Garza, Victoria, Liang, Yanke, Jackson, Katrina L, Moustakim, Moses

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