An Evidence‐Based Framework for Evaluating Pharmacogenomics Knowledge for Personalized Medicine von Whirl‐Carrillo, Michelle, Huddart, Rachel, Gong, Li, Sangkuhl, Katrin, Thorn, Caroline F., Whaley, Ryan, Klein, Teri E.

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Prediction of CYP2D6 phenotype from genotype across world populations von Gaedigk, Andrea, Sangkuhl, Katrin, Whirl-Carrillo, Michelle, Klein, Teri, Leeder, J. Steven

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Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2D6, OPRM1, and COMT Genotypes and Select Opioid Therapy von Crews, Kristine R., Monte, Andrew A., Huddart, Rachel, Caudle, Kelly E., Kharasch, Evan D., Gaedigk, Andrea, Dunnenberger, Henry M., Leeder, J. Steven, Callaghan, John T., Samer, Caroline Flora, Klein, Teri E., Haidar, Cyrine E., Van Driest, Sara L., Ruano, Gualberto, Sangkuhl, Katrin, Cavallari, Larisa H., Müller, Daniel J., Prows, Cynthia A., Nagy, Mohamed, Somogyi, Andrew A., Skaar, Todd C.

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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C19 and Proton Pump Inhibitor Dosing von Lima, John J., Thomas, Cameron D., Barbarino, Julia, Desta, Zeruesenay, Van Driest, Sara L., El Rouby, Nihal, Johnson, Julie A., Cavallari, Larisa H., Shakhnovich, Valentina, Thacker, David L., Scott, Stuart A., Schwab, Matthias, Uppugunduri, Chakradhara Rao S., Formea, Christine M., Franciosi, James P., Sangkuhl, Katrin, Gaedigk, Andrea, Klein, Teri E., Gammal, Roseann S., Furuta, Takahisa

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PharmVar GeneFocus: CYP2D6 von Nofziger, Charity, Turner, Amy J., Sangkuhl, Katrin, Whirl‐Carrillo, Michelle, Agúndez, José A.G., Black, John L., Dunnenberger, Henry M., Ruano, Gualberto, Kennedy, Martin A., Phillips, Michael S., Hachad, Houda, Klein, Teri E., Gaedigk, Andrea

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Standardizing CYP2D6 Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and Dutch Pharmacogenetics Working Gr... von Caudle, Kelly E., Sangkuhl, Katrin, Whirl‐Carrillo, Michelle, Swen, Jesse J., Haidar, Cyrine E., Klein, Teri E., Gammal, Roseann S., Relling, Mary V., Scott, Stuart A., Hertz, Daniel L., Guchelaar, Henk‐Jan, Gaedigk, Andrea

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Clinical Pharmacogenetics Implementation Consortium Guideline for Cytochrome P450 (CYP)2D6 Genotype and Atomoxetine Therapy von Brown, Jacob T., Bishop, Jeffrey R., Sangkuhl, Katrin, Nurmi, Erika L., Mueller, Daniel J., Dinh, Jean C., Gaedigk, Andrea, Klein, Teri E., Caudle, Kelly E., McCracken, James T., Leon, Jose, Leeder, J. Steven

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Transfer learning enables prediction of CYP2D6 haplotype function von McInnes, Gregory, Dalton, Rachel, Sangkuhl, Katrin, Whirl-Carrillo, Michelle, Lee, Seung-Been, Tsao, Philip S, Gaedigk, Andrea, Altman, Russ B, Woodahl, Erica L

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PharmVar GeneFocus: CYP2C9 von Sangkuhl, Katrin, Claudio‐Campos, Karla, Cavallari, Larisa H., Agundez, Jose A.G., Whirl‐Carrillo, Michelle, Duconge, Jorge, Del Tredici, Andria L., Wadelius, Mia, Rodrigues Botton, Mariana, Woodahl, Erica L., Scott, Stuart A., Klein, Teri E., Pratt, Victoria M., Daly, Ann K., Gaedigk, Andrea

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PharmVar GeneFocus: CYP3A5 von Rodriguez‐Antona, Cristina, Savieo, Jessica L., Lauschke, Volker M., Sangkuhl, Katrin, Drögemöller, Britt I., Wang, Danxin, Schaik, Ron H. N., Gilep, Andrei A., Peter, Arul P., Boone, Erin C., Ramey, Bronwyn E., Klein, Teri E., Whirl‐Carrillo, Michelle, Pratt, Victoria M., Gaedigk, Andrea

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Evaluating the frequency and the impact of pharmacogenetic alleles in an ancestrally diverse Biobank population von Verma, Shefali S, Keat, Karl, Li, Binglan, Hoffecker, Glenda, Risman, Marjorie, Sangkuhl, Katrin, Whirl-Carrillo, Michelle, Dudek, Scott, Verma, Anurag, Klein, Teri E, Ritchie, Marylyn D, Tuteja, Sony

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Selective serotonin reuptake inhibitors pathway von Sangkuhl, Katrin, Klein, Teri E, Altman, Russ B

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Mutant G-protein-coupled receptors as a cause of human diseases von Schöneberg, Torsten, Schulz, Angela, Biebermann, Heike, Hermsdorf, Thomas, Römpler, Holger, Sangkuhl, Katrin

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P662: Estimating UK Biobank population-specific PGx allele and phenotype frequencies using PharmCAT von Sangkuhl, Katrin, Whaley, Ryan, Woon, Mark, Keat, Karl, Gong, Li, Whirl-Carrillo, Michelle, Ritchie, Marylyn, Klein, Teri

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Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder von Amare, Azmeraw T, Schubert, Klaus Oliver, Tekola-Ayele, Fasil, Hsu, Yi-Hsiang, Sangkuhl, Katrin, Jenkins, Gregory, Whaley, Ryan M, Barman, Poulami, Batzler, Anthony, Altman, Russ B, Arolt, Volker, Brockmöller, Jürgen, Chen, Chia-Hui, Domschke, Katharina, Hall-Flavin, Daniel K, Hong, Chen-Jee, Illi, Ari, Ji, Yuan, Kampman, Olli, Kinoshita, Toshihiko, Leinonen, Esa, Liou, Ying-Jay, Mushiroda, Taisei, Nonen, Shinpei, Skime, Michelle K, Wang, Liewei, Kato, Masaki, Liu, Yu-Li, Praphanphoj, Verayuth, Stingl, Julia C, Bobo, William V, Tsai, Shih-Jen, Kubo, Michiaki, Klein, Teri E, Weinshilboum, Richard M, Biernacka, Joanna M, Baune, Bernhard T

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Identification of Receptors and Signaling Pathways for Orphan Bone Morphogenetic Protein/Growth Differentiation Factor Ligands Based on Genomic Analyses von Mazerbourg, Sabine, Sangkuhl, Katrin, Luo, Ching-Wei, Sudo, Satoko, Klein, Cynthia, Hsueh, Aaron J.W.

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PharmGKB: Understanding the Effects of Individual Genetic Variants von Sangkuhl, Katrin, Berlin, Dorit S., Altman, Russ B., Klein, Teri E.

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P570: Generating a framework for curating mechanism of disease in monogenic conditions: A consensus effort of the Gene Curation Coalition von DiStefano, Marina, Alkuraya, Fowzan, Amberger, Joanna, Austin-Tse, Christina, Austine, Ola, Balzotti, Marie, Berg, Jonathan, Bruford, Elspeth, Byrne, Alicia, Cibrian-Uhalte, Elena, Coffey, Alison, Firth, Helen, Hamosh, Ada, Hunt, Sarah, Klein, Teri, Kurtz, Catherine, Leigh, Sarah, Leong, Ivone, Lucano, Caterina, Maddirevula, Sateesh, O'Neill, Audrey, Puzriakova, Arina, Rath, Ana, Roberts, Angharad, Radtke, Kelly, Ramos, Erin, Riggs, Erin, Rodwell, Charlotte, Taylor, Julie, Sangkuhl, Katrin, Snow, Catherine, Stark, Zornitza, Ware, James, Wayburn, Bess, Weller, Phillip, Rehm, Heidi

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P451: The Gene Curation Coalition works to resolve discrepancies in gene-disease validity assertions von DiStefano, Marina, Amberger, Joanna, Austin-Tse, Christina, Balzotti, Marie, Amin, Mutaz, Berg, Jonathan, Bocchini, Carol, Bruford, Elspeth, Alkuraya, Fowzan, Coffey, Alison, Collins, Heather, Cunningham, Fiona, Firth, Helen, Fitzpatrick, David, Einhorn, Yaron, Goldstein, Jennifer, Hamosh, Ada, Leigh, Sarah, Leong, Ivone, Martin, Christa, McDonagh, Ellen, Puzriakova, Arina, Rath, Ana, Roberts, Angharad, Radtke, Kelly, Ramos, Erin, Riggs, Erin, Rodwell, Charlotte, Sangkuhl, Katrin, Snow, Catherine, Stark, Zornitza, Tahiliani, Jackie, Ware, James, Williams, Eleanor, Wright, Caroline, Yates, Michael, Weller, Phillip, Rehm, Heidi

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Pharmacogenetics at Scale: An Analysis of the UK Biobank von McInnes, Gregory, Lavertu, Adam, Sangkuhl, Katrin, Klein, Teri E., Whirl‐Carrillo, Michelle, Altman, Russ B.

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