Current Therapeutic Advances Targeting EGFR and EGFRvIII in Glioblastoma von Padfield, Emily, Ellis, Hayley P, Kurian, Kathreena M

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Pharmacokinetics, safety, and tolerability of olaparib and temozolomide for recurrent glioblastoma: results of the phase I OPARATIC trial von Hanna, Catherine, Kurian, Kathreena M, Williams, Karin, Watts, Colin, Jackson, Alan, Carruthers, Ross, Strathdee, Karen, Cruickshank, Garth, Dunn, Laurence, Erridge, Sara, Godfrey, Lisa, Jefferies, Sarah, McBain, Catherine, Sleigh, Rebecca, McCormick, Alex, Pittman, Marc, Halford, Sarah, Chalmers, Anthony J

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Molecular diagnostic tools for the World Health Organization (WHO) 2021 classification of gliomas, glioneuronal and neuronal tumors; an EANO guideline von Sahm, Felix, Brandner, Sebastian, Bertero, Luca, Capper, David, French, Pim J, Figarella-Branger, Dominique, Giangaspero, Felice, Haberler, Christine, Hegi, Monika E, Kristensen, Bjarne W, Kurian, Kathreena M, Preusser, Matthias, Tops, Bastiaan B J, van den Bent, Martin, Wick, Wolfgang, Reifenberger, Guido, Wesseling, Pieter

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Replication Stress Drives Constitutive Activation of the DNA Damage Response and Radioresistance in Glioblastoma Stem-like Cells von Carruthers, Ross D, Ahmed, Shafiq U, Ramachandran, Shaliny, Strathdee, Karen, Kurian, Kathreena M, Hedley, Ann, Gomez-Roman, Natividad, Kalna, Gabriela, Neilson, Mathew, Gilmour, Lesley, Stevenson, Katrina H, Hammond, Ester M, Chalmers, Anthony J

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Role of DNA methylation in the relationship between glioma risk factors and glioma incidence: a two-step Mendelian randomization study von Howell, Amy E., Relton, Caroline, Martin, Richard M., Zheng, Jie, Kurian, Kathreena M.

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Current Understanding of BRAF Alterations in Diagnosis, Prognosis, and Therapeutic Targeting in Pediatric Low-Grade Gliomas von Penman, Catherine Louise, Faulkner, Claire, Lowis, Stephen P, Kurian, Kathreena M

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Pre-diagnostic blood biomarkers for adult glioma von Andrews, Lily J, Davies, Philippa, Herbert, Christopher, Kurian, Kathreena M

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Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis von Huang, Miller, Tailor, Jignesh, Zhen, Qiqi, Gillmor, Aaron H., Miller, Matthew L., Weishaupt, Holger, Chen, Justin, Zheng, Tina, Nash, Emily K., McHenry, Lauren K., An, Zhenyi, Ye, Fubaiyang, Takashima, Yasuhiro, Clarke, James, Ayetey, Harold, Cavalli, Florence M.G., Luu, Betty, Moriarity, Branden S., Ilkhanizadeh, Shirin, Chavez, Lukas, Yu, Chunying, Kurian, Kathreena M., Magnaldo, Thierry, Sevenet, Nicolas, Koch, Philipp, Pollard, Steven M., Dirks, Peter, Snyder, Michael P., Largaespada, David A., Cho, Yoon Jae, Phillips, Joanna J., Swartling, Fredrik J., Morrissy, A. Sorana, Kool, Marcel, Pfister, Stefan M., Taylor, Michael D., Smith, Austin, Weiss, William A.

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Liquid biopsies for early diagnosis of brain tumours: in silico mathematical biomarker modelling von Blee, Johanna A, Liu, Xia, Harland, Abigail J, Fatania, Kavi, Currie, Stuart, Kurian, Kathreena M, Hauert, Sabine

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Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology von Qaddoumi, Ibrahim, Orisme, Wilda, Wen, Ji, Santiago, Teresa, Gupta, Kirti, Dalton, James D., Tang, Bo, Haupfear, Kelly, Punchihewa, Chandanamali, Easton, John, Mulder, Heather, Boggs, Kristy, Shao, Ying, Rusch, Michael, Becksfort, Jared, Gupta, Pankaj, Wang, Shuoguo, Lee, Ryan P., Brat, Daniel, Peter Collins, V., Dahiya, Sonika, George, David, Konomos, William, Kurian, Kathreena M., McFadden, Kathryn, Serafini, Luciano Neder, Nickols, Hilary, Perry, Arie, Shurtleff, Sheila, Gajjar, Amar, Boop, Fredrick A., Klimo, Paul D., Mardis, Elaine R., Wilson, Richard K., Baker, Suzanne J., Zhang, Jinghui, Wu, Gang, Downing, James R., Tatevossian, Ruth G., Ellison, David W.

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Evaluating circulating tumour cell enrichment techniques to establish an appropriate method for clinical application in glioblastomas von Barber, Hannah R, Perks, Claire M, Kurian, Kathreena M

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Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner von Stricker, Stefan H, Feber, Andrew, Engström, Pär G, Carén, Helena, Kurian, Kathreena M, Takashima, Yasuhiro, Watts, Colin, Way, Michael, Dirks, Peter, Bertone, Paul, Smith, Austin, Beck, Stephan, Pollard, Steven M

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Current Challenges in Glioblastoma: Intratumour Heterogeneity, Residual Disease, and Models to Predict Disease Recurrence von Ellis, Hayley P, Greenslade, Mark, Powell, Ben, Spiteri, Inmaculada, Sottoriva, Andrea, Kurian, Kathreena M

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Brain multi-omic Mendelian randomisation to identify novel drug targets for gliomagenesis von Thornton, Zak A, Andrews, Lily J, Zhao, Huiling, Zheng, Jie, Paternoster, Lavinia, Robinson, Jamie W, Kurian, Kathreena M

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Targeting the Ubiquitin System in Glioblastoma von Scholz, Nico, Kurian, Kathreena M, Siebzehnrubl, Florian A, Licchesi, Julien D F

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Glioma Stem-Like Cells and Metabolism: Potential for Novel Therapeutic Strategies von Harland, Abigail, Liu, Xia, Ghirardello, Mattia, Galan, M. Carmen, Perks, Claire M., Kurian, Kathreena M.

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Prevalence of BRAFV600 in glioma and use of BRAF Inhibitors in patients with BRAFV600 mutation-positive glioma: systematic review von Andrews, Lily J, Thornton, Zak A, Saincher, Saanwalshah S, Yao, Ian Y, Dawson, Sarah, McGuinness, Luke A, Jones, Hayley E, Jefferies, Sarah, Short, Susan C, Cheng, Hung-Yuan, McAleenan, Alexandra, Higgins, Julian P T, Kurian, Kathreena M

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Human Endogenous Retrovirus Type K Promotes Proliferation and Confers Sensitivity to Antiretroviral Drugs in Merlin-Negative Schwannoma and Meningioma von Maze, Emmanuel A, Agit, Bora, Reeves, Shona, Hilton, David A, Parkinson, David B, Laraba, Liyam, Ercolano, Emanuela, Kurian, Kathreena M, Hanemann, C Oliver, Belshaw, Robert D, Ammoun, Sylwia

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MGMT promoter methylation testing to predict overall survival in people with glioblastoma treated with temozolomide: a comprehensive meta-analysis based on a Cochrane Systematic Re... von Brandner, Sebastian, McAleenan, Alexandra, Kelly, Claire, Spiga, Francesca, Cheng, Hung-Yuan, Dawson, Sarah, Schmidt, Lena, Faulkner, Claire L, Wragg, Christopher, Jefferies, Sarah, Higgins, Julian P T, Kurian, Kathreena M

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Targeting MERTK on tumour cells and macrophages: a potential intervention for sporadic and NF2-related meningioma and schwannoma tumours von Dave, Foram, Herrera, Kevin, Lockley, Alex, van de Weijer, Laurien L., Henderson, Summer, Sofela, Agbolahan A., Hook, Laura, Adams, Claire L., Ercolano, Emanuela, Hilton, David A., Maze, Emmanuel A., Kurian, Kathreena M., Ammoun, Sylwia, Hanemann, C. Oliver

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