486 Development of small molecule activators of protein phosphatase 2A for the treatment of lung cancer von Sangodkar, J, Mazhar, S, Kastrinsky, D, Ohlmeyer, M, Narla, G

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548 Development of a small molecule activator of protein phosphatase 2A for the treatment of prostate cancer von McClinch, K, Callejas, D, Cooper, M, Stachnik, A, Kastrinsky, D, Ohlmeyer, M, Galsky, M, Narla, G

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DNA Alkylation Properties of Yatakemycin von Parrish, Jay P, Kastrinsky, David B, Wolkenberg, Scott E, Igarashi, Yasuhiro, Boger, Dale L

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Total Synthesis, Structure Revision, and Absolute Configuration of (+)-Yatakemycin von Tichenor, Mark S, Kastrinsky, David B, Boger, Dale L

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Effective Asymmetric Synthesis of 1,2,9,9a-Tetrahydrocyclopropa[c]benzo[e]indol-4-one (CBI) von Kastrinsky, David B, Boger, Dale L

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Establishment of substituent effects in the DNA binding subunit of CBI analogues of the duocarmycins and CC-1065 von Parrish, Jay P., Kastrinsky, David B., Stauffer, Frederic, Hedrick, Michael P., Hwang, Inkyu, Boger, Dale L.

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Synthesis and Evaluation of Duocarmycin and CC-1065 Analogues Incorporating the 1,2,9,9a-Tetrahydrocyclopropa[c]benz[e]-3-azaindol-4-one (CBA) Alkylation Subunit von Parrish, Jay P, Kastrinsky, David B, Hwang, Inkyu, Boger, Dale L

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Synthesis and X-ray Analysis of an Unprecedented and Stable 2-Aza-4,4-spirocyclopropacyclohexadienone von Parrish, Jay P, Kastrinsky, David B, Boger, Dale L

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Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth von Sangodkar, J, Perl, A, Tohme, R, Kiselar, J, Kastrinsky, DB, Zaware, N, Izadmehr, S, Mazhar, S, Wiredja, DD, O’Connor, CM, Hoon, D, Dhawan, NS, Schlatzer, D, Yao, S, Leonard, D, Borczuk, AC, Gokulrangan, G, Wang, L, Svenson, E, Farrington, CC, Yuan, E, Avelar, RA, Stachnik, A, Smith, B, Gidwani, V, Giannini, HM, McQuaid, D, McClinch, K, Wang, Z, Levine, AC, Sears, RC, Chen, EY, Duan, Q, Datt, M, Haider, S, Ma’ayan, A, DiFeo, A, Sharma, N, Galsky, MD, Brautigan, DL, Ioannou, YA, Xu, W, Chance, MR, Ohlmeyer, M, Narla, G

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All roads lead to PP2A: exploiting the therapeutic potential of this phosphatase von Sangodkar, Jaya, Farrington, Caroline C., McClinch, Kimberly, Galsky, Matthew D., Kastrinsky, David B., Narla, Goutham

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Small-Molecule Activators of Protein Phosphatase 2A for the Treatment of Castration-Resistant Prostate Cancer von McClinch, Kimberly, Avelar, Rita A, Callejas, David, Izadmehr, Sudeh, Wiredja, Danica, Perl, Abbey, Sangodkar, Jaya, Kastrinsky, David B, Schlatzer, Daniela, Cooper, Maxwell, Kiselar, Janna, Stachnik, Agnes, Yao, Shen, Hoon, Divya, McQuaid, Daniel, Zaware, Nilesh, Gong, Yixuan, Brautigan, David L, Plymate, Stephen R, Sprenger, Cynthia C T, Oh, William K, Levine, Alice C, Kirschenbaum, Alexander, Sfakianos, John P, Sears, Rosalie, DiFeo, Analisa, Ioannou, Yiannis, Ohlmeyer, Michael, Narla, Goutham, Galsky, Matthew D

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Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth von Sangodkar, Jaya, Perl, Abbey, Tohme, Rita, Kiselar, Janna, Kastrinsky, David B, Zaware, Nilesh, Izadmehr, Sudeh, Mazhar, Sahar, Wiredja, Danica D, O'Connor, Caitlin M, Hoon, Divya, Dhawan, Neil S, Schlatzer, Daniela, Yao, Shen, Leonard, Daniel, Borczuk, Alain C, Gokulrangan, Giridharan, Wang, Lifu, Svenson, Elena, Farrington, Caroline C, Yuan, Eric, Avelar, Rita A, Stachnik, Agnes, Smith, Blake, Gidwani, Vickram, Giannini, Heather M, McQuaid, Daniel, McClinch, Kimberly, Wang, Zhizhi, Levine, Alice C, Sears, Rosalie C, Chen, Edward Y, Duan, Qiaonan, Datt, Manish, Haider, Shozeb, Ma'ayan, Avi, DiFeo, Analisa, Sharma, Neelesh, Galsky, Matthew D, Brautigan, David L, Ioannou, Yiannis A, Xu, Wenqing, Chance, Mark R, Ohlmeyer, Michael, Narla, Goutham

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Asymmetric Total Synthesis of (+)- and ent-(−)-Yatakemycin and Duocarmycin SA:  Evaluation of Yatakemycin Key Partial Structures and Its Unnatural Enantiomer von Tichenor, Mark S, Trzupek, John D, Kastrinsky, David B, Shiga, Futoshi, Hwang, Inkyu, Boger, Dale L

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C104 INDOOR AND OUTDOOR POLLUTION: EPIDEMIOLOGY AND MECHANISMS: Photochemical Reaction Altered Cardiac Toxicity Of Diesel Exhaust Inhalation von Tong, H, McIntosh-Kastrinsky, R, Sexton, K, Diaz-Sanchez, D

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All roads lead to PP 2A: exploiting the therapeutic potential of this phosphatase von Sangodkar, Jaya, Farrington, Caroline C., McClinch, Kimberly, Galsky, Matthew D., Kastrinsky, David B., Narla, Goutham

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Asymmetric Total Synthesis of (+)- and ent-(-)-Yatakemycin (I) and Duocarmycin SA (II): Evaluation of Yatakemycin Key Partial Structures and Its Unnatural Enantiomer von Tichenor, Mark S., Trzupek, John D., Kastrinsky, David B., Shiga, Futoshi, Hwang, Inkyu, Boger, Dale L.

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