Opportunistic Infections, Mortality Risk, and Prevention Strategies in Patients With Vacuoles, E1 Enzyme, X-Linked, Autoinflammatory, Somatic (VEXAS) Syndrome von Czech, Mary, Cuellar-Rodriguez, Jennifer, Patel, Bhavisha A, Groarke, Emma M, Cowen, Edward W, Turturice, Benjamin, Beck, David B, Wilson, Lorena, Goodspeed, Wendy, Darden, Ivana, Young, Neal S, Hickstein, Dennis, Ombrello, Amanda, Hoffman, Patrycjia, Arikan, Evsen Apaydin, Sinaii, Ninet, Hathaway, Londa, Castelo-Soccio, Leslie, Fike, Alice, Kastner, Daniel B, Grayson, Peter C, Ferrada, Marcela A

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A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases von Coll, Rebecca C, Robertson, Avril A B, Chae, Jae Jin, Higgins, Sarah C, Muñoz-Planillo, Raúl, Inserra, Marco C, Vetter, Irina, Dungan, Lara S, Monks, Brian G, Stutz, Andrea, Croker, Daniel E, Butler, Mark S, Haneklaus, Moritz, Sutton, Caroline E, Núñez, Gabriel, Latz, Eicke, Kastner, Daniel L, Mills, Kingston H G, Masters, Seth L, Schroder, Kate, Cooper, Matthew A, O'Neill, Luke A J

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Disorders of ubiquitylation: unchained inflammation von Beck, David B., Werner, Achim, Kastner, Daniel L., Aksentijevich, Ivona

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Hippocampal replay reflects specific past experiences rather than a plan for subsequent choice von Gillespie, Anna K., Astudillo Maya, Daniela A., Denovellis, Eric L., Liu, Daniel F., Kastner, David B., Coulter, Michael E., Roumis, Demetris K., Eden, Uri T., Frank, Loren M.

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Ancient familial Mediterranean fever mutations in human pyrin and resistance to Yersinia pestis von Park, Yong Hwan, Remmers, Elaine F., Lee, Wonyong, Ombrello, Amanda K., Chung, Lawton K., Shilei, Zhao, Stone, Deborah L., Ivanov, Maya I., Loeven, Nicole A., Barron, Karyl S., Hoffmann, Patrycja, Nehrebecky, Michele, Akkaya-Ulum, Yeliz Z., Sag, Erdal, Balci-Peynircioglu, Banu, Aksentijevich, Ivona, Gül, Ahmet, Rotimi, Charles N., Chen, Hua, Bliska, James B., Ozen, Seza, Kastner, Daniel L., Shriner, Daniel, Chae, Jae Jin

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The Yersinia Virulence Factor YopM Hijacks Host Kinases to Inhibit Type III Effector-Triggered Activation of the Pyrin Inflammasome von Chung, Lawton K., Park, Yong Hwan, Zheng, Yueting, Brodsky, Igor E., Hearing, Patrick, Kastner, Daniel L., Chae, Jae Jin, Bliska, James B.

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Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease von Zhou, Qing, Yu, Xiaomin, Demirkaya, Erkan, Deuitch, Natalie, Stone, Deborah, Tsai, Wanxia Li, Kuehn, Hye Sun, Wang, Hongying, Yang, Dan, Park, Yong Hwan, Ombrello, Amanda K., Blake, Mary, Romeo, Tina, Remmers, Elaine F., Chae, Jae Jin, Mullikin, James C., Güzel, Ferhat, Milner, Joshua D., Boehm, Manfred, Rosenzweig, Sergio D., Gadina, Massimo, Welch, Steven B., Özen, Seza, Topaloglu, Rezan, Abinun, Mario, Kastner, Daniel L., Aksentijevich, Ivona

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The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP von Lee, Geun-Shik, Subramanian, Naeha, Kim, Andrew I., Aksentijevich, Ivona, Goldbach-Mansky, Raphaela, Sacks, David B., Germain, Ronald N., Kastner, Daniel L., Chae, Jae Jin

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A hypermorphic missense mutation in PLCG2, encoding phospholipase Cγ2, causes a dominantly inherited autoinflammatory disease with immunodeficiency von Zhou, Qing, Lee, Geun-Shik, Brady, Jillian, Datta, Shrimati, Katan, Matilda, Sheikh, Afzal, Martins, Marta S, Bunney, Tom D, Santich, Brian H, Moir, Susan, Kuhns, Douglas B, Long Priel, Debra A, Ombrello, Amanda, Stone, Deborah, Ombrello, Michael J, Khan, Javed, Milner, Joshua D, Kastner, Daniel L, Aksentijevich, Ivona

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Mutant UBA1 and Severe Adult-Onset Autoinflammatory Disease. Reply von Beck, David B, Grayson, Peter C, Kastner, Daniel L

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Estimated Prevalence and Clinical Manifestations of UBA1 Variants Associated With VEXAS Syndrome in a Clinical Population von Beck, David B, Bodian, Dale L, Shah, Vandan, Mirshahi, Uyenlinh L, Kim, Jung, Ding, Yi, Magaziner, Samuel J, Strande, Natasha T, Cantor, Anna, Haley, Jeremy S, Cook, Adam, Hill, Wesley, Schwartz, Alan L, Grayson, Peter C, Ferrada, Marcela A, Kastner, Daniel L, Carey, David J, Stewart, Douglas R

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Microfluidics based manufacture of liposomes simultaneously entrapping hydrophilic and lipophilic drugs von Joshi, Sameer, Hussain, Maryam T., Roces, Carla B., Anderluzzi, Giulia, Kastner, Elisabeth, Salmaso, Stefano, Kirby, Daniel J., Perrie, Yvonne

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Somatic Mutations in UBA1 Define a Distinct Subset of Relapsing Polychondritis Patients With VEXAS von Ferrada, Marcela A., Sikora, Keith A., Luo, Yiming, Wells, Kristina V., Patel, Bhavisha, Groarke, Emma M., Ospina Cardona, Daniela, Rominger, Emily, Hoffmann, Patrycja, Le, Mimi T., Deng, Zuoming, Quinn, Kaitlin A., Rose, Emily, Tsai, Wanxia L., Wigerblad, Gustaf, Goodspeed, Wendy, Jones, Anne, Wilson, Lorena, Schnappauf, Oskar, Laird, Ryan S., Kim, Jeff, Allen, Clint, Sirajuddin, Arlene, Chen, Marcus, Gadina, Massimo, Calvo, Katherine R., Kaplan, Mariana J., Colbert, Robert A., Aksentijevich, Ivona, Young, Neal S., Savic, Sinisa, Kastner, Daniel L., Ombrello, Amanda K., Beck, David B., Grayson, Peter C.

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Second Case of HOIP Deficiency Expands Clinical Features and Defines Inflammatory Transcriptome Regulated by LUBAC von Oda, Hirotsugu, Beck, David B, Kuehn, Hye Sun, Sampaio Moura, Natalia, Hoffmann, Patrycja, Ibarra, Maria, Stoddard, Jennifer, Tsai, Wanxia Li, Gutierrez-Cruz, Gustavo, Gadina, Massimo, Rosenzweig, Sergio D, Kastner, Daniel L, Notarangelo, Luigi D, Aksentijevich, Ivona

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Translation of cytoplasmic UBA1 contributes to VEXAS syndrome pathogenesis von Ferrada, Marcela A., Savic, Sinisa, Cardona, Daniela Ospina, Collins, Jason C., Alessi, Hugh, Gutierrez-Rodrigues, Fernanda, Kumar, Dinesh Babu Uthaya, Wilson, Lorena, Goodspeed, Wendy, Topilow, James S., Paik, Julie J., Poulter, James A., Kermani, Tanaz A., Koster, Matthew J., Warrington, Kenneth J., Cargo, Catherine, Tattersall, Rachel S., Duncan, Christopher J.A., Cantor, Anna, Hoffmann, Patrycja, Payne, Elspeth M., Bonnekoh, Hanna, Krause, Karoline, Cowen, Edward W., Calvo, Katherine R., Patel, Bhavisha A., Ombrello, Amanda K., Kastner, Daniel L., Young, Neal S., Werner, Achim, Grayson, Peter C., Beck, David B.

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Spectrum of clonal hematopoiesis in VEXAS syndrome von Gutierrez-Rodrigues, Fernanda, Kusne, Yael, Fernandez, Jenna, Lasho, Terra, Shalhoub, Ruba, Ma, Xiaoyang, Alessi, Hugh, Finke, Christy, Koster, Matthew J., Mangaonkar, Abhishek, Warrington, Kenneth J., Begna, Kebede, Xie, Zhuoer, Ombrello, Amanda K., Viswanatha, David, Ferrada, Marcela, Wilson, Lorena, Go, Ronald, Kourelis, Taxiarchis, Reichard, Kaaren, Olteanu, Horatiu, Darden, Ivana, Hironaka, Dalton, Alemu, Lemlem, Kajigaya, Sachiko, Rosenzweig, Sofia, Calado, Rodrigo T., Groarke, Emma M., Kastner, Daniel L., Calvo, Katherine R., Wu, Colin O., Grayson, Peter C., Young, Neal S., Beck, David B., Patel, Bhavisha A., Patnaik, Mrinal M.

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Global analyses of human immune variation reveal baseline predictors of postvaccination responses von Tsang, John S, Schwartzberg, Pamela L, Kotliarov, Yuri, Biancotto, Angelique, Xie, Zhi, Germain, Ronald N, Wang, Ena, Olnes, Matthew J, Narayanan, Manikandan, Golding, Hana, Moir, Susan, Dickler, Howard B, Perl, Shira, Cheung, Foo

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VEXAS Syndrome and Disease Taxonomy in Rheumatology von Grayson, Peter C., Beck, David B., Ferrada, Marcela A., Nigrovic, Peter A., Kastner, Daniel L.

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A guiding map for inflammation von Netea, Mihai G, Balkwill, Frances, Chonchol, Michel, Cominelli, Fabio, Donath, Marc Y, Giamarellos-Bourboulis, Evangelos J, Golenbock, Douglas, Gresnigt, Mark S, Heneka, Michael T, Hoffman, Hal M, Hotchkiss, Richard, Joosten, Leo A B, Kastner, Daniel L, Korte, Martin, Latz, Eicke, Libby, Peter, Mandrup-Poulsen, Thomas, Mantovani, Alberto, Mills, Kingston H G, Nowak, Kristen L, O'Neill, Luke A, Pickkers, Peter, van der Poll, Tom, Ridker, Paul M, Schalkwijk, Joost, Schwartz, David A, Siegmund, Britta, Steer, Clifford J, Tilg, Herbert, van der Meer, Jos W M, van de Veerdonk, Frank L, Dinarello, Charles A

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Efficacy of etanercept in the tumor necrosis factor receptor-associated periodic syndrome: A prospective, open-label, dose-escalation study von Bulua, Ariel C., Mogul, Douglas B., Aksentijevich, Ivona, Singh, Harjot, He, David Y., Muenz, Larry R., Ward, Michael M., Yarboro, Cheryl H., Kastner, Daniel L., Siegel, Richard M., Hull, Keith M.

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