Tissue-specific CTCF–cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo von Hanssen, Lars L. P., Kassouf, Mira T., Oudelaar, A. Marieke, Biggs, Daniel, Preece, Chris, Downes, Damien J., Gosden, Matthew, Sharpe, Jacqueline A., Sloane-Stanley, Jacqueline A., Hughes, Jim R., Davies, Benjamin, Higgs, Douglas R.

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The characteristics of CTCF binding sequences contribute to enhancer blocking activity von Tsang, Felice H, Stolper, Rosa J, Hanifi, Muhammad, Cornell, Lucy J, Francis, Helena S, Davies, Benjamin, Higgs, Douglas R, Kassouf, Mira T

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A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions von Brown, Jill M., Roberts, Nigel A., Graham, Bryony, Waithe, Dominic, Lagerholm, Christoffer, Telenius, Jelena M., De Ornellas, Sara, Oudelaar, A. Marieke, Scott, Caroline, Szczerbal, Izabela, Babbs, Christian, Kassouf, Mira T., Hughes, Jim R., Higgs, Douglas R., Buckle, Veronica J.

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Scalable in vitro production of defined mouse erythroblasts von Francis, Helena S, Harold, Caroline L, Beagrie, Robert A, King, Andrew J, Gosden, Matthew E, Blayney, Joseph W, Jeziorska, Danuta M, Babbs, Christian, Higgs, Douglas R, Kassouf, Mira T

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Genetic dissection of the α-globin super-enhancer in vivo von Hay, Deborah, Hughes, Jim R, Babbs, Christian, Davies, James O J, Graham, Bryony J, Hanssen, Lars L P, Kassouf, Mira T, Oudelaar, A Marieke, Sharpe, Jacqueline A, Suciu, Maria C, Telenius, Jelena, Williams, Ruth, Rode, Christina, Li, Pik-Shan, Pennacchio, Len A, Sloane-Stanley, Jacqueline A, Ayyub, Helena, Butler, Sue, Sauka-Spengler, Tatjana, Gibbons, Richard J, Smith, Andrew J H, Wood, William G, Higgs, Douglas R

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The mouse alpha-globin cluster: a paradigm for studying genome regulation and organization von Oudelaar, A Marieke, Beagrie, Robert A, Kassouf, Mira T, Higgs, Douglas R

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Genome-wide identification of TAL1's functional targets: insights into its mechanisms of action in primary erythroid cells von Kassouf, Mira T, Hughes, Jim R, Taylor, Stephen, McGowan, Simon J, Soneji, Shamit, Green, Angela L, Vyas, Paresh, Porcher, Catherine

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Reactivation of a developmentally silenced embryonic globin gene von King, Andrew J., Songdej, Duantida, Downes, Damien J., Beagrie, Robert A., Liu, Siyu, Buckley, Megan, Hua, Peng, Suciu, Maria C., Marieke Oudelaar, A., Hanssen, Lars L. P., Jeziorska, Danuta, Roberts, Nigel, Carpenter, Stephanie J., Francis, Helena, Telenius, Jelena, Olijnik, Aude-Anais, Sharpe, Jacqueline A., Sloane-Stanley, Jacqueline, Eglinton, Jennifer, Kassouf, Mira T., Orkin, Stuart H., Pennacchio, Len A., Davies, James O. J., Hughes, Jim R., Higgs, Douglas R., Babbs, Christian

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Between form and function: the complexity of genome folding von Oudelaar, A Marieke, Hanssen, Lars L P, Hardison, Ross C, Kassouf, Mira T, Hughes, Jim R, Higgs, Douglas R

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Differential use of SCL/TAL-1 DNA-binding domain in developmental hematopoiesis von Kassouf, Mira T., Chagraoui, Hedia, Vyas, Paresh, Porcher, Catherine

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Scalable in vitro production of defined mouse erythroblasts von Helena S Francis, Caroline L Harold, Robert A Beagrie, Andrew J King, Matthew E Gosden, Joseph W Blayney, Danuta M Jeziorska, Christian Babbs, Douglas R Higgs, Mira T Kassouf

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Genetic dissection of the [alpha]-globin super-enhancer in vivo von Hay, Deborah, Hughes, Jim R, Babbs, Christian, Davies, James O J, Graham, Bryony J, Hanssen, Lars L P, Kassouf, Mira T, Oudelaar, A Marieke, Sharpe, Jacqueline A, Suciu, Maria C, Telenius, Jelena, Williams, Ruth, Rode, Christina, Li, Pik-Shan, Pennacchio, Len A, Sloane-Stanley, Jacqueline A, Ayyub, Helena, Butler, Sue, Sauka-Spengler, Tatjana, Gibbons, Richard J, Smith, Andrew J H, Wood, William G, Higgs, Douglas R

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3110 – MULTIPARTITE SUPER-ENHANCERS MAY ACT IN AN ORIENTATION-DEPENDENT MANNER von Kassouf, Mira

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Developing a pill to treat sickle cell disease von Higgs, Douglas, Kassouf, Mira

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Understanding fundamental principles of enhancer biology at a model locus: Analysing the structure and function of an enhancer cluster at the α-globin locus von Kassouf, Mira, Ford, Seren, Blayney, Joseph, Higgs, Doug

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1005 – SWITCHING GENES ON AND OFF DURING HAEMATOPOIESIS von Higgs, Douglas, Tsang, Felice, Cornell, Lucy, Tunnacliffe, Ed, Kassouf, Mira

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Super-enhancers include classical enhancers and facilitators to fully activate gene expression von Blayney, Joseph W, Francis, Helena, Rampasekova, Alexandra, Camellato, Brendan, Mitchell, Leslie, Stolper, Rosa, Cornell, Lucy, Babbs, Christian, Boeke, Jef D, Higgs, Douglas R, Kassouf, Mira

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2022 American Society of Clinical Oncology von Basappa, Naveen S, Kassouf, Elie, Fallah-Rad, Nazanin, Keyes, Mira, Swaminath, Anand, Loblaw, Andrew, Black, Peter C

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2022 American Society of Clinical Oncology (ASCO): Meeting highlights von Black, Peter C, Fallah-Rad, Nazanin, Loblaw, Andrew, Kassouf, Elie, Keyes, Mira, Basappa, Naveen S, Swaminath, Anand

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SCL-mediated regulation of the cell-cycle regulator p21 is critical for murine megakaryopoiesis von Chagraoui, Hedia, Kassouf, Mira, Banerjee, Sreemoti, Goardon, Nicolas, Clark, Kevin, Atzberger, Ann, Pearce, Andrew C., Skoda, Radek C., Ferguson, David J.P., Watson, Steve P., Vyas, Paresh, Porcher, Catherine

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