368 GDC-0068, a Novel and Selective Akt Inhibitor Demonstrates Improvement in Anti-tumor Activity When Combined with Androgen Receptor Pathway Antagonists, MDV3100 and Abiraterone,... von Nannini, M.A, Arrazate, A, Bower, J, Lee, L.B, Lin, J, Lee, B.B, Kassees, R, Lin, K, Sampath, D

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220 POSTER Combination of class I PI3K inhibitor, GDC-0941, with standard of care therapeutics results in enhanced anti-tumor responses in human cancer models in vitro and in vivo von Sampath, D, Belvin, M, Guan, J, Edgar, K, Wallin, J, Prior, W.W, Kassees, R, Moore, P, Patel, S, Friedman, L

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GDC-0980 is a novel class I PI3K/mTOR kinase inhibitor with robust activity in cancer models driven by the PI3K pathway von Wallin, Jeffrey J, Edgar, Kyle A, Guan, Jane, Berry, Megan, Prior, Wei Wei, Lee, Leslie, Lesnick, John D, Lewis, Cristina, Nonomiya, Jim, Pang, Jodie, Salphati, Laurent, Olivero, Alan G, Sutherlin, Daniel P, O'Brien, Carol, Spoerke, Jill M, Patel, Sonal, Lensun, Letitia, Kassees, Robert, Ross, Leanne, Lackner, Mark R, Sampath, Deepak, Belvin, Marcia, Friedman, Lori S

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Abstract 5676: Preclinical evaluation of estrogen receptor coregulator binding inhibitor ERX-245 in breast cancer von Viswanadhapalli, Suryavathi, Ma, Shihong, Lee, Tae Kyung, Liu, Xihui, Kassees, Kara, Pratap, Uday P., Liu, Junhao, Tang, Weiwei, Tekmal, Rajeshwar R., Ahn, Jung-Mo, Raj, Ganesh V., Vadlamudi, Ratna K.

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Abstract P5-04-23: Enhancing the activity of a novel estrogen receptor coregulator binding modulator (ERX-11) against ER-positive therapy resistant breast cancer von Viswanadhapalli, S, Ma, S, Lee, T-K, Sareddy, GR, Liu, X, Ekoue, D, Alluri, A, Luo, Y, Kassees, K, Arteaga, C, Alluri, P, Weintraub, SE, Tekmal, RR, Ahn, J-M, Raj, GV, Vadlamudi, RK

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Novel LIPA-Targeted Therapy for Treating Ovarian Cancer von Collier, Alexia B, Viswanadhapalli, Suryavathi, Gopalam, Rahul, Lee, Tae-Kyung, Kassees, Kara, Parra, Karla, Sharma, Gaurav, Reese, Tanner C, Liu, Xihui, Yang, Xue, Ebrahimi, Behnam, Pratap, Uday P, Mahajan, Megharani, Arnold, William C, Baker, Adriana, Chen, Chia-Yuan, Elmore, Scott Terry, Subbarayalu, Panneerdoss, Sareddy, Gangadhara R, Valente, Philip T, Kost, Edward R, Ahn, Jung-Mo, Vadlamudi, Ratna K

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Abstract 3986: Novel LIPA targeted therapy for treating ovarian cancer von Collier, Alexia B., Viswanadhapalli, Suryavathi, Lee, Tae-Kyung, Kassees, Kara, Parra, Karla, Sharma, Gaurav, Reese, Tanner, Hsieh, Michael, Liu, Xihui, Yang, Xue, Ebrahimi, Behnam, Pratap, Uday P., Gopalam, Rahul, Chen, Chia Yuan, Elmore, Scott Terry, Sareddy, Gangadhara Reddy, Kost, Edward R., Ahn, Jung-Mo, Raj, Ganesh V., Vadlamudi, Ratna K.

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