Rational design of biodegradable sulphonamide candidates treating septicaemia by synergistic dual inhibition of COX-2/PGE2 axis and DHPS enzyme von El-Dershaby, Nada H., El-Hawash, Soad A., Kassab, Shaymaa E., Dabees, Hoda G., Abdel Moneim, Ahmed E., Abdel Wahab, Ibrahim A., Abd-Alhaseeb, Mohammad M., El-Miligy, Mostafa M. M.

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Rational Design and Synthesis of New Selective COX-2 Inhibitors with In Vivo PGE2-Lowering Activity by Tethering Benzenesulfonamide and 1,2,3-Triazole Pharmacophores to Some NSAIDs von El-Dershaby, Nada H, El-Hawash, Soad A, Kassab, Shaymaa E, Daabees, Hoda G, Abdel Moneim, Ahmed E, El-Miligy, Mostafa M. M

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Structure-based design generated novel hydroxamic acid based preferential HDAC6 lead inhibitor with on-target cytotoxic activity against primary choroid plexus carcinoma von Kassab, Shaymaa E., Mowafy, Samar, Alserw, Aya M., Seliem, Joustin A., El-Naggar, Shahenda M., Omar, Nesreen N., Awad, Mohamed M.

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Design, synthesis, 3D pharmacophore, QSAR, and docking studies of carboxylic acid derivatives as Histone Deacetylase inhibitors and cytotoxic agents von Abdel-Atty, Mona M., Farag, Nahla A., Kassab, Shaymaa E., Serya, Rabah A.T., Abouzid, Khaled A.M.

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AI-DPAPT: a machine learning framework for predicting PROTAC activity von Abouzied, Amr S, Alshammari, Bahaa, Kari, Hayam, Huwaimel, Bader, Alqarni, Saad, Kassab, Shaymaa E

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Synthesis of novel d-α-galactopyranosyl-l-seryl/l-threonyl-l-alanyl-l-alanine as useful precursors of new glycopeptide antibiotics with computational calculations studies von Khodair, Ahmed I., Kassab, Shaymaa E., Kheder, Nabila A., Fahim, Asmaa M.

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Base-catalyzed one-step synthesis of 5,7-disubstituted-1,2,4-triazolo[1,5-a]pyrimidines von He, Xinhua, Kassab, Shaymaa E., Heinzl, Geoffrey, Xue, Fengtian

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Camptothecin structure simplification elaborated new imidazo[2,1-b]quinazoline derivative as a human topoisomerase I inhibitor with efficacy against bone cancer cells and colon ade... von Khodair, Ahmed I., El-Hallouty, Salwa M., Cagle-White, Brittnee, Abdel Aziz, May H., Hanafy, Mahmoud Kh, Mowafy, Samar, Hamdy, Nadia M., Kassab, Shaymaa E.

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Discovery of new indomethacin-based analogs with potentially selective cyclooxygenase-2 inhibition and observed diminishing to PGE2 activities von Kassab, Shaymaa E., Khedr, Mohammed A., Ali, Hamed I., Abdalla, Mohamed M.

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Febuxostat-based amides and some derived heterocycles targeting xanthine oxidase and COX inhibition. Synthesis, in vitro and in vivo biological evaluation, molecular modeling and i... von Rashad, Aya Y., Kassab, Shaymaa E., Daabees, Hoda G., Abdel Moneim, Ahmed E., Rostom, Sherif A.F.

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Structure-based design and synthesis of conformationally constrained derivatives of methyl-piperidinopyrazole (MPP) with estrogen receptor (ER) antagonist activity von Ragab, Mahmoud A., Elagawany, Mohamed, Daabees, Hoda, Ahmed, Al-Shaimaa F., Awad, Eman M., Billon, Cyrielle, Elgendy, Bahaa, Abouzid, Khaled A.M., Kassab, Shaymaa E.

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Design, synthesis and biological evaluation of novel thiohydantoin derivatives as antiproliferative agents: A combined experimental and theoretical assessments von Elbadawi, Mostafa M., Khodair, Ahmed I., Awad, Mohamed K., Kassab, Shaymaa E., Elsaady, Mohammed T., Abdellatif, Khaled R.A.

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ChemInform Abstract: Base-Catalyzed One-Step Synthesis of 5,7-Disubstituted-1,2,4-triazolo[1,5-a]pyrimidines von He, Xinhua, Kassab, Shaymaa E., Heinzl, Geoffrey, Xue, Fengtian

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ChemInform Abstract: Synthesis of New 9-Glycosyl-4,9-dihydropyrano[3,4-b]indole-1(3H)-ones as Antibacterial Agents von Kassab, Shaymaa E., Hegazy, Gehan H., Eid, Nahed M., Amin, Kamelia M., El-Gendy, Adel A.

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ChemInform Abstract: Synthesis of 1H-Indole-2,3-dione-3-thiosemicarbazone Ribonucleosides as Antibacterial Agents von Kassab, Shaymaa E., Hegazy, Gehan H., Eid, Nahed M., Amin, Kamelia M., El-Gendy, Adel A.

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