Selective uptake and sustained expression of AAV vectors following subcutaneous delivery von Donahue, Brian A., McArthur, James G., Spratt, S. Kaye, Bohl, Delphine, Lagarde, Catherine, Sanchez, Lisa, Kaspar, Brian A., Sloan, Barbara A., Lee, Ya Li, Danos, Olivier, Snyder, Richard O.

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Single-Dose Gene-Replacement Therapy for Spinal Muscular Atrophy von Mendell, Jerry R, Al-Zaidy, Samiah, Shell, Richard, Arnold, W. Dave, Rodino-Klapac, Louise R, Prior, Thomas W, Lowes, Linda, Alfano, Lindsay, Berry, Katherine, Church, Kathleen, Kissel, John T, Nagendran, Sukumar, L’Italien, James, Sproule, Douglas M, Wells, Courtney, Cardenas, Jessica A, Heitzer, Marjet D, Kaspar, Allan, Corcoran, Sarah, Braun, Lyndsey, Likhite, Shibi, Miranda, Carlos, Meyer, Kathrin, Foust, K.D, Burghes, Arthur H.M, Kaspar, Brian K

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Macrophage Migration Inhibitory Factor as a Chaperone Inhibiting Accumulation of Misfolded SOD1 von Israelson, Adrian, Ditsworth, Dara, Sun, Shuying, Song, SungWon, Liang, Jason, Hruska-Plochan, Marian, McAlonis-Downes, Melissa, Abu-Hamad, Salah, Zoltsman, Guy, Shani, Tom, Maldonado, Marcus, Bui, Anh, Navarro, Michael, Zhou, Huilin, Marsala, Martin, Kaspar, Brian K., Da Cruz, Sandrine, Cleveland, Don W.

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Microglia Induce Motor Neuron Death via the Classical NF-κB Pathway in Amyotrophic Lateral Sclerosis von Frakes, Ashley E., Ferraiuolo, Laura, Haidet-Phillips, Amanda M., Schmelzer, Leah, Braun, Lyndsey, Miranda, Carlos J., Ladner, Katherine J., Bevan, Adam K., Foust, Kevin D., Godbout, Jonathan P., Popovich, Phillip G., Guttridge, Denis C., Kaspar, Brian K.

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Single-Dose Gene-Replacement Therapy for Spinal Muscular Atrophy von Mendell, Jerry R., Al-Zaidy, Samiah, Shell, Richard, Arnold, W. Dave, Rodino-Klapac, Louise R., Prior, Thomas W., Lowes, Linda, Alfano, Lindsay, Berry, Katherine, Church, Kathleen, Kissel, John T., Nagendran, Sukumar, L’Italien, James, Sproule, Douglas M., Wells, Courtney, Cardenas, Jessica A., Heitzer, Marjet D., Kaspar, Allan, Corcoran, Sarah, Braun, Lyndsey, Likhite, Shibi, Miranda, Carlos, Meyer, Kathrin, Foust, K.D., Burghes, Arthur H.M., Kaspar, Brian K.

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Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS von Sun, Shuying, Sun, Ying, Ling, Shuo-Chien, Ferraiuolo, Laura, McAlonis-Downes, Melissa, Zou, Yiyang, Drenner, Kevin, Wang, Yin, Ditsworth, Dara, Tokunaga, Seiya, Kopelevich, Alex, Kaspar, Brian K., Lagier-Tourenne, Clotilde, Cleveland, Don W.

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A yeast platform for high-level synthesis of tetrahydroisoquinoline alkaloids von Pyne, Michael E., Kevvai, Kaspar, Grewal, Parbir S., Narcross, Lauren, Choi, Brian, Bourgeois, Leanne, Dueber, John E., Martin, Vincent J. J.

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Retrograde Viral Delivery of IGF-1 Prolongs Survival in a Mouse ALS Model von Kaspar, Brian K., Lladó, Jerònia, Sherkat, Nushin, Rothstein, Jeffrey D., Gage, Fred H.

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Improving Single Injection CSF Delivery of AAV9-mediated Gene Therapy for SMA: A Dose–response Study in Mice and Nonhuman Primates von Meyer, Kathrin, Ferraiuolo, Laura, Schmelzer, Leah, Braun, Lyndsey, McGovern, Vicki, Likhite, Shibi, Michels, Olivia, Govoni, Alessandra, Fitzgerald, Julie, Morales, Pablo, Foust, Kevin D, Mendell, Jerry R, Burghes, Arthur H M, Kaspar, Brian K

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Adeno-Associated Virus Serotype 9 Transduction in the Central Nervous System of Nonhuman Primates von SAMARANCH, Lluis, SALEGIO, Ernesto A, SAN SEBASTIAN, Waldy, KELLS, Adrian P, FOUST, Kevin D, BRINGAS, John R, LAMARRE, Clementine, FORSAYETH, John, KASPAR, Brian K, BANKIEWICZ, Krystof S

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Chronic oligodendrogenesis and remyelination after spinal cord injury in mice and rats von Hesp, Zoe C, Goldstein, Evan Z, Goldstein, Evan A, Miranda, Carlos J, Kaspar, Brian K, Kaspar, Brain K, McTigue, Dana M

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Application of Plasmonic Bowtie Nanoantenna Arrays for Optical Trapping, Stacking, and Sorting von Roxworthy, Brian J, Ko, Kaspar D, Kumar, Anil, Fung, Kin Hung, Chow, Edmond K. C, Liu, Gang Logan, Fang, Nicholas X, Toussaint, Kimani C

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Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS von Meyer, Kathrin, Ferraiuolo, Laura, Miranda, Carlos J., Likhite, Shibi, McElroy, Sohyun, Renusch, Samantha, Ditsworth, Dara, Lagier-Tourenne, Clotilde, Smith, Richard A., Ravits, John, Burghes, Arthur H., Shaw, Pamela J., Cleveland, Don W., Kolb, Stephen J., Kaspar, Brian K.

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Glia–neuron interactions in neurological diseases: Testing non-cell autonomy in a dish von Meyer, Kathrin, Kaspar, Brian K

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Oligodendrocytes contribute to motor neuron death in ALS via SOD1-dependent mechanism von Ferraiuolo, Laura, Meyer, Kathrin, Sherwood, Thomas W., Vick, Jonathan, Likhite, Shibi, Frakes, Ashley, Miranda, Carlos J., Braun, Lyndsey, Heath, Paul R., Pineda, Ricardo, Beattie, Christine E., Shaw, Pamela J., Askwith, Candice C., McTigue, Dana, Kaspar, Brian K.

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A role for glia in the progression of Rett’s syndrome von Lioy, Daniel T., Garg, Saurabh K., Monaghan, Caitlin E., Raber, Jacob, Foust, Kevin D., Kaspar, Brian K., Hirrlinger, Petra G., Kirchhoff, Frank, Bissonnette, John M., Ballas, Nurit, Mandel, Gail

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Targeted Delivery of Self-Complementary Adeno-Associated Virus Serotype 9 to the Brain, Using Magnetic Resonance Imaging-Guided Focused Ultrasound von THEVENOT, Emmanuel, JORDAO, Jessica F, O'REILLY, Meaghan A, MARKHAM, Kelly, WENG, Ying-Qi, FOUST, Kevin D, KASPAR, Brian K, HYNYNEN, Kullervo, AUBERT, Isabelle

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Astrocytes from familial and sporadic ALS patients are toxic to motor neurons von Kaspar, Brian K, Haidet-Phillips, Amanda M, Hester, Mark E, Miranda, Carlos J, Meyer, Kathrin, Braun, Lyndsey, Frakes, Ashley, Song, SungWon, Likhite, Shibi, Murtha, Matthew J, Foust, Kevin D, Rao, Meghan, Eagle, Amy, Kammesheidt, Anja, Christensen, Ashley, Mendell, Jerry R, Burghes, Arthur H M

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Directed evolution of adeno-associated virus yields enhanced gene delivery vectors von Schaffer, David V, Maheshri, Narendra, Koerber, James T, Kaspar, Brian K

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Systemic delivery of MeCP2 rescues behavioral and cellular deficits in female mouse models of Rett syndrome von Garg, Saurabh K, Lioy, Daniel T, Cheval, Hélène, McGann, James C, Bissonnette, John M, Murtha, Matthew J, Foust, Kevin D, Kaspar, Brian K, Bird, Adrian, Mandel, Gail

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