Structure-Guided Design of Conformationally Constrained Cyclohexane Inhibitors of Severe Acute Respiratory Syndrome Coronavirus‑2 3CL Protease von Dampalla, Chamandi S, Kim, Yunjeong, Bickmeier, Naemi, Rathnayake, Athri D, Nguyen, Harry Nhat, Zheng, Jian, Kashipathy, Maithri M, Baird, Matthew A, Battaile, Kevin P, Lovell, Scott, Perlman, Stanley, Chang, Kyeong-Ok, Groutas, William C

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Structure-Guided Design of Potent Spirocyclic Inhibitors of Severe Acute Respiratory Syndrome Coronavirus‑2 3C-like Protease von Dampalla, Chamandi S., Rathnayake, Athri D., Galasiti Kankanamalage, Anushka C., Kim, Yunjeong, Perera, Krishani Dinali, Nguyen, Harry Nhat, Miller, Matthew J., Madden, Trent K., Picard, Hunter R., Thurman, Hayden A., Kashipathy, Maithri M., Liu, Lijun, Battaile, Kevin P., Lovell, Scott, Chang, Kyeong-Ok, Groutas, William C.

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Structure–activity relationship of ipglycermide binding to phosphoglycerate mutases von Wiedmann, Mareike, Dranchak, Patricia K., Aitha, Mahesh, Queme, Bryan, Collmus, Christopher D., Kashipathy, Maithri M., Kanter, Liza, Lamy, Laurence, Rogers, Joseph M., Tao, Dingyin, Battaile, Kevin P., Rai, Ganesha, Lovell, Scott, Suga, Hiroaki, Inglese, James

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Histidine Protonation and Conformational Switching in Diphtheria Toxin Translocation Domain von Rodnin, Mykola V, Vasques-Montes, Victor, Kyrychenko, Alexander, Oliveira, Nuno F B, Kashipathy, Maithri M, Battaile, Kevin P, Douglas, Justin, Lovell, Scott, Machuqueiro, Miguel, Ladokhin, Alexey S

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Structure of the Diphtheria Toxin at Acidic pH: Implications for the Conformational Switching of the Translocation Domain von Rodnin, Mykola V, Kashipathy, Maithri M, Kyrychenko, Alexander, Battaile, Kevin P, Lovell, Scott, Ladokhin, Alexey S

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Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection von Dampalla, Chamandi S., Zheng, Jian, Perera, Krishani Dinali, Wong, Lok-Yin Roy, Meyerholz, David K., Nguyen, Harry Nhat, Kashipathy, Maithri M., Battaile, Kevin P., Lovell, Scott, Kim, Yunjeong, Perlman, Stanley, Groutas, William C., Chang, Kyeong-Ok

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The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase von Alhammad, Yousef M O, Kashipathy, Maithri M, Roy, Anuradha, Gagné, Jean-Philippe, McDonald, Peter, Gao, Philip, Nonfoux, Louis, Battaile, Kevin P, Johnson, David K, Holmstrom, Erik D, Poirier, Guy G, Lovell, Scott, Fehr, Anthony R

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Mechanism-Based Macrocyclic Inhibitors of Serine Proteases von Damalanka, Vishnu C., Banas, Victoria, De Bona, Paolo, Kashipathy, Maithri M., Battaile, Kevin, Lovell, Scott, Janetka, James W.

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The N‐terminal intrinsically disordered region of Ncb5or docks with the cytochrome b5 core to form a helical motif that is of ancient origin von Benson, David R, Deng, Bin, Kashipathy, Maithri M, Lovell, Scott, Battaile, Kevin P, Cooper, Anne, Gao, Philip, Fenton, Aron W, Zhu, Hao

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The N-terminal intrinsically disordered region of Ncb5or docks with the cytochrome b 5 core to form a helical motif that is of ancient origin von Benson, David R, Deng, Bin, Kashipathy, Maithri M, Lovell, Scott, Battaile, Kevin P, Cooper, Anne, Gao, Philip, Fenton, Aron W, Zhu, Hao

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Pseudomonas aeruginosa Dps (PA0962) Functions in H2O2 Mediated Oxidative Stress Defense and Exhibits In Vitro DNA Cleaving Activity von Rajapaksha, Nimesha, Soldano, Anabel, Yao, Huili, Donnarumma, Fabrizio, Kashipathy, Maithri M., Seibold, Steve, Battaile, Kevin P., Lovell, Scott, Rivera, Mario

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Structure-Guided Design of Potent Inhibitors of SARS-CoV‑2 3CL Protease: Structural, Biochemical, and Cell-Based Studies von Dampalla, Chamandi S, Rathnayake, Athri D, Perera, Krishani Dinali, Jesri, Abdul-Rahman M, Nguyen, Harry Nhat, Miller, Matthew J, Thurman, Hayden A, Zheng, Jian, Kashipathy, Maithri M, Battaile, Kevin P, Lovell, Scott, Perlman, Stanley, Kim, Yunjeong, Groutas, William C, Chang, Kyeong-Ok

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Use of protease substrate specificity screening in the rational design of selective protease inhibitors with unnatural amino acids: Application to HGFA, matriptase, and hepsin von Mahoney, Matthew W., Helander, Jonathan, Kooner, Anoopjit S., Norman, Mariah, Damalanka, Vishnu C., De Bona, Paolo, Kasperkiewicz, Paulina, Rut, Wioletta, Poreba, Marcin, Kashipathy, Maithri M., Battaile, Kevin P., Lovell, Scott, O'Donoghue, Anthony J., Craik, Charles S., Drag, Marcin, Janetka, James W.

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Molecular insights into the structure and function of the Staphylococcus aureus fatty acid kinase von Myers, Megan J., Xu, Zhen, Ryan, Benjamin J., DeMars, Zachary R., Ridder, Miranda J., Johnson, David K., Krute, Christina N., Flynn, Tony S., Kashipathy, Maithri M., Battaile, Kevin P., Schnicker, Nicholas, Lovell, Scott, Freudenthal, Bret D., Bose, Jeffrey L.

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Structural insight into the novel iron‐coordination and domain interactions of transferrin‐1 from a model insect, Manduca sexta von Weber, Jacob J., Kashipathy, Maithri M., Battaile, Kevin P., Go, Eden, Desaire, Heather, Kanost, Michael R., Lovell, Scott, Gorman, Maureen J.

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Structure-Guided Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease von Rathnayake, Athri D, Kim, Yunjeong, Dampalla, Chamandi S, Nguyen, Harry Nhat, Jesri, Abdul-Rahman M, Kashipathy, Maithri M, Lushington, Gerald H, Battaile, Kevin P, Lovell, Scott, Chang, Kyeong-Ok, Groutas, William C

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Costameric integrin and sarcoglycan protein levels are altered in a Drosophila model for Limb-girdle muscular dystrophy type 2H von Bawa, Simranjot, Gameros, Samantha, Baumann, Kenny, Brooks, David S, Kollhoff, Joseph A, Zolkiewski, Michal, Re Cecconi, Andrea David, Panini, Nicolò, Russo, Massimo, Piccirillo, Rosanna, Johnson, David K, Kashipathy, Maithri M, Battaile, Kevin P, Lovell, Scott, Bouyain, Samuel E A, Kawakami, Jessica, Geisbrecht, Erika R

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Crystal Structure of VapBC-1 from Nontypeable Haemophilus influenzae and the Effect of PIN Domain Mutations on Survival during Infection von Molinaro, Ashley L, Kashipathy, Maithri M, Lovell, Scott, Battaile, Kevin P, Coussens, Nathan P, Shen, Min, Daines, Dayle A

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RNA structures and dynamics with Å resolution revealed by x-ray free-electron lasers von Zielinski, Kara A., Sui, Shuo, Pabit, Suzette A., Rivera, Daniel A., Wang, Tong, Hu, Qingyue, Kashipathy, Maithri M., Lisova, Stella, Schaffer, Chris B., Mariani, Valerio, Hunter, Mark S., Kupitz, Christopher, Moss, Frank R., Poitevin, Frédéric P., Grant, Thomas D., Pollack, Lois

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Broad-Spectrum Cyclopropane-Based Inhibitors of Coronavirus 3C-like Proteases: Biochemical, Structural, and Virological Studies von Dampalla, Chamandi S., Nguyen, Harry Nhat, Rathnayake, Athri D., Kim, Yunjeong, Perera, Krishani Dinali, Madden, Trent K., Thurman, Hayden A., Machen, Alexandra J., Kashipathy, Maithri M., Liu, Lijun, Battaile, Kevin P., Lovell, Scott, Chang, Kyeong-Ok, Groutas, William C.

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