Microwave-Accelerated McKenna Synthesis of Phosphonic Acids: An Investigation von Mustafa, Dana, Overhulse, Justin M, Kashemirov, Boris A, McKenna, Charles E

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The relationship between the chemistry and biological activity of the bisphosphonates von Ebetino, Frank H, Hogan, Anne-Marie L, Sun, Shuting, Tsoumpra, Maria K, Duan, Xuchen, Triffitt, James T, Kwaasi, Aaron A, Dunford, James E, Barnett, Bobby L, Oppermann, Udo, Lundy, Mark W, Boyde, Alan, Kashemirov, Boris A, McKenna, Charles E, Russell, R. Graham G

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Design and Synthesis of Cathepsin-K-Activated Osteoadsorptive Fluorogenic Sentinel (OFS) Probes for Detecting Early Osteoclastic Bone Resorption in a Multiple Myeloma Mouse Model von Richard, Eric T, Morinaga, Kenzo, Zheng, Yiying, Sundberg, Oskar, Hokugo, Akishige, Hui, Kimberly, Zhou, Yipin, Sasaki, Hodaka, Kashemirov, Boris A, Nishimura, Ichiro, McKenna, Charles E

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Selective BET bromodomain inhibition as an antifungal therapeutic strategy von Mietton, Flore, Ferri, Elena, Champleboux, Morgane, Zala, Ninon, Maubon, Danièle, Zhou, Yingsheng, Harbut, Mike, Spittler, Didier, Garnaud, Cécile, Courçon, Marie, Chauvel, Murielle, d’Enfert, Christophe, Kashemirov, Boris A., Hull, Mitchell, Cornet, Muriel, McKenna, Charles E., Govin, Jérôme, Petosa, Carlo

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Influence of bone affinity on the skeletal distribution of fluorescently labeled bisphosphonates in vivo von Roelofs, Anke J, Stewart, Charlotte A, Sun, Shuting, Błażewska, Katarzyna M, Kashemirov, Boris A, McKenna, Charles E, Russell, R Graham G, Rogers, Michael J, Lundy, Mark W, Ebetino, Frank H, Coxon, Fraser P

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A Novel Small Molecule Neurotrophin-3 Analogue Promotes Inner Ear Neurite Outgrowth and Synaptogenesis In vitro von Kempfle, Judith S., Duro, Marlon, Zhang, Andrea, Amador, Carolina D., Kuang, Richard, Lu, Ryan, Kashemirov, Boris A., Edge, Albert S., McKenna, Charles E., Jung, David H.

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Fluorescent Bisphosphonate and Carboxyphosphonate Probes: A Versatile Imaging Toolkit for Applications in Bone Biology and Biomedicine von Sun, Shuting, Błażewska, Katarzyna M, Kadina, Anastasia P, Kashemirov, Boris A, Duan, Xuchen, Triffitt, James T, Dunford, James E, Russell, R. Graham G, Ebetino, Frank H, Roelofs, Anke J, Coxon, Fraser P, Lundy, Mark W, McKenna, Charles E

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Fluorescent risedronate analogue 800CW-pRIS improves tooth extraction-associated abnormal wound healing in zoledronate-treated mice von Okawa, Hiroko, Kondo, Takeru, Hokugo, Akishige, Cherian, Philip, Sundberg, Oskar, Campagna, Jesus J., Kashemirov, Boris A., John, Varghese, Sun, Shuting, Ebetino, Frank H., McKenna, Charles E., Nishimura, Ichiro

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Synthesis, Chiral High Performance Liquid Chromatographic Resolution and Enantiospecific Activity of a Potent New Geranylgeranyl Transferase Inhibitor, 2-Hydroxy-3-imidazo[1,2-a]py... von McKenna, Charles E, Kashemirov, Boris A, Błażewska, Katarzyna M, Mallard-Favier, Isabelle, Stewart, Charlotte A, Rojas, Javier, Lundy, Mark W, Ebetino, Frank H, Baron, Rudi A, Dunford, James E, Kirsten, Marie L, Seabra, Miguel C, Bala, Joy L, Marma, Mong S, Rogers, Michael J, Coxon, Fraser P

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Synthesis of 8-oxo-dGTP and its β,γ-CH2-, β,γ-CHF-, and β,γ-CF2- analogues von Zheng, Yiying, Haratipour, Pouya, Kashemirov, Boris A., McKenna, Charles E.

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Phosphonocarboxylates Inhibit the Second Geranylgeranyl Addition by Rab Geranylgeranyl Transferase von Baron, Rudi A., Tavaré, Richard, Figueiredo, Ana C., Błazżewska, Katarzyna M., Kashemirov, Boris A., McKenna, Charles E., Ebetino, Frank H., Taylor, Adam, Rogers, Michael J., Coxon, Fraser P., Seabra, Miguel C.

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Synthesis and biological evaluation of fluorinated deoxynucleotide analogs based on bis-(difluoromethylene)triphosphoric acid von Prakash, G. K. Surya, Zibinsky, Mikhail, Upton, Thomas G., Kashemirov, Boris A., McKenna, Charles E., Oertell, Keriann, Goodman, Myron F., Batra, Vinod K., Pedersen, Lars C., Beard, William A., Shock, David D., Wilson, Samuel H., Olah, George A.

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Bisphosphonate Binding Affinity Affects Drug Distribution in Both Intracortical and Trabecular Bone of Rabbits von Turek, John, Ebetino, F. Hal, Lundy, Mark W., Sun, Shuting, Kashemirov, Boris A., McKenna, Charles E., Gallant, Maxime A., Plotkin, Lilian I., Bellido, Teresita, Duan, Xuchen, Triffitt, James T., Russell, R. Graham G., Burr, David B., Allen, Matthew R.

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Uridine Bisphosphonates Differentiate Phosphoglycosyl Transferase Superfamilies von Seebald, Leah M., Haratipour, Pouya, Jacobs, Michaela R., Bernstein, Hannah M., Kashemirov, Boris A., McKenna, Charles E., Imperiali, Barbara

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1‐(α‐Aminobenzyl)‐2‐naphthol: A New Chiral Auxiliary for the Synthesis of Enantiopure α‐Aminophosphonic Acids von Metlushka, Kirill E., Kashemirov, Boris A., Zheltukhin, Viktor F., Sadkova, Dilyara N., Büchner, Bernd, Hess, Christian, Kataeva, Olga N., McKenna, Charles E., Alfonsov, Vladimir A.

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Modifying the Basicity of the dNTP Leaving Group Modulates Precatalytic Conformational Changes of DNA Polymerase β von Alnajjar, Khadijeh S., Wang, Katarina, Alvarado-Cruz, Isabel, Chavira, Cristian, Negahbani, Amirsoheil, Nakhjiri, Maryam, Minard, Corinne, Garcia-Barboza, Beatriz, Kashemirov, Boris A., McKenna, Charles E., Goodman, Myron F., Sweasy, Joann B.

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Kinetic Effects of beta,gamma-Modified Deoxynucleoside 5 '-Triphosphate Analogues on RNA-Catalyzed Polymerization of DNA von Setterholm, Noah A., Haratipour, Pouya, Kashemirov, Boris A., McKenna, Charles E., Joyce, Gerald F.

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Toward more potent imidazopyridine inhibitors of Candida albicans Bdf1: Modeling the role of structural waters in selective ligand binding von Zhou, Yingsheng, Overhulse, Justin M., Dupper, Nathan J., Guo, Yanchun, Kashemirov, Boris A., Wei, Kaiyao, Govin, Jérôme, Petosa, Carlo, McKenna, Charles E.

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Synthesis and anti-cancer potential of potent peripheral MAOA inhibitors designed to limit blood:brain penetration von Jacobs, Michaela R., Olivero, Jennifer E., Ok Choi, Hyun, Liao, Chun-Peng, Kashemirov, Boris A., Katz, Jonathan E., Gross, Mitchell E., McKenna, Charles E.

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Oral USC-093, a novel homoserinamide analogue of the tyrosinamide (S)-HPMPA prodrug USC-087 has decreased nephrotoxicity while maintaining antiviral efficacy against human adenovir... von Tollefson, Ann E., Riemann, Samantha B., Ying, Baoling, Spencer, Jacqueline F., Overhulse, Justin M., Kashemirov, Boris A., Wold, William S.M., McKenna, Charles E., Toth, Karoly

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