A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity von van der Lee, Sven J., Conway, Olivia J., Jansen, Iris, Carrasquillo, Minerva M., Kleineidam, Luca, van den Akker, Erik, Hernández, Isabel, van Eijk, Kristel R., Stringa, Najada, Chen, Jason A., Zettergren, Anna, Andlauer, Till F. M., Diez-Fairen, Monica, Simon-Sanchez, Javier, Lleó, Alberto, Zetterberg, Henrik, Nygaard, Marianne, Blauwendraat, Cornelis, Savage, Jeanne E., Mengel-From, Jonas, Moreno-Grau, Sonia, Wagner, Michael, Fortea, Juan, Keogh, Michael J., Blennow, Kaj, Skoog, Ingmar, Friese, Manuel A., Pletnikova, Olga, Zulaica, Miren, Lage, Carmen, de Rojas, Itziar, Riedel-Heller, Steffi, Illán-Gala, Ignacio, Wei, Wei, Jeune, Bernard, Orellana, Adelina, Then Bergh, Florian, Wang, Xue, Hulsman, Marc, Beker, Nina, Tesi, Niccolo, Morris, Christopher M., Indakoetxea, Begoña, Collij, Lyduine E., Scherer, Martin, Morenas-Rodríguez, Estrella, Ironside, James W., van Berckel, Bart N. M., Wiendl, Heinz, Strickland, Samantha L., Pastor, Pau, Rodríguez Rodríguez, Eloy, Boeve, Bradley F., Petersen, Ronald C., Ferman, Tanis J., van Gerpen, Jay A., Reinders, Marcel J. T., Uitti, Ryan J., Tárraga, Lluís, Maier, Wolfgang, Dols-Icardo, Oriol, Kawalia, Amit, Dalmasso, Maria Carolina, Boada, Mercè, Zettl, Uwe K., van Schoor, Natasja M., Beekman, Marian, Allen, Mariet, Masliah, Eliezer, de Munain, Adolfo López, Pantelyat, Alexander, Wszolek, Zbigniew K., Ross, Owen A., Dickson, Dennis W., Graff-Radford, Neill R., Knopman, David, Rademakers, Rosa, Lemstra, Afina W., Pijnenburg, Yolande A. L., Scheltens, Philip, Gasser, Thomas, Chinnery, Patrick F, Hemmer, Bernhard, Huisman, Martijn A., Troncoso, Juan, Moreno, Fermin, Nohr, Ellen A., Sørensen, Thorkild I. A., Heutink, Peter, Sánchez-Juan, Pascual, Posthuma, Danielle, Clarimón, Jordi, Christensen, Kaare, Ertekin-Taner, Nilüfer, Scholz, Sonja W., Ramirez, Alfredo, Ruiz, Agustín, Slagboom, Eline, van der Flier, Wiesje M., Holstege, Henne

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Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study von Nicholas, Jennifer, Grossman, Murray, McMillan, Corey T, Massimo, Lauren, Van Deerlin, Vivianna M, Warren, Jason D, Fox, Nick C, Bocchetta, Martina, Boeve, Bradley F, Knopman, David S, Rademakers, Rosa, van Swieten, John C, Meeter, Lieke H, Dopper, Elise GP, Snowden, Julie S, Saxon, Jennifer, Pickering-Brown, Stuart, Le Ber, Isabelle, Brice, Alexis, Caroppo, Paola, Ghidoni, Roberta, Pievani, Michela, Binetti, Giuliano, Dickerson, Bradford C, Lucente, Diane, Graff, Caroline, Ghoshal, Nupur, Galimberti, Daniela, Scarpini, Elio, Mackenzie, Ian R, Hsiung, Ging-Yuek R, Sengdy, Pheth, Boxer, Adam L, Taylor, Joanne B, Synofzik, Matthis, Wilke, Carlo, Sulzer, Patricia, Kwok, John, Lladó, Albert, Borrego-Ecija, Sergi, Santana, Isabel, Almeida, Maria Rosário, Tábuas-Pereira, Miguel, Moreno, Fermin, Barandiaran, Myriam, Indakoetxea, Begoña, Levin, Johannes, Danek, Adrian, Rowe, James B, Anderl-Straub, Sarah, Masellis, Mario, Black, Sandra E, Lautrette, Geraldine, Vandenberghe, Rik, Rogalski, Emily J, Weintraub, Sandra, Gerhard, Alexander, Onyike, Chiadi U, Papageorgiou, Sokratis G, Bras, Jose, Rohrer, Jonathan D, Heller, Carolin, Convery, Rhian S, Shafei, Rachelle M, Jones, David T, Baker, Matt, Gavrilova, Ralitza, Domoto-Reilly, Kimiko, Poos, Jackie M, Van der Ende, Emma L, Panman, Jessica L, Seelaar, Harro, Fostinelli, Silvia, Chiang, Huei-Hsin, Arighi, Andrea, Fenoglio, Chiara, Heuer, Hilary, Miller, Bruce, Karydas, Anna, Fong, Jamie, João Leitão, Maria, Santiago, Beatriz, Ferreira, Carlos, De Arriba, Maria, Tainta, Mikel, Zulaica, Miren, Ferreira, Catarina, Semler, Elisa, Ludolph, Albert, Miltenberger, Gabriel, Rogaeva, Ekaterina, Bruffaerts, Rose, Vandenbulcke, Mathieu, Mesulam, M Marsel, Bigio, Eileen, Kroupis, Christos, Stefanis, Leonidas, Shoesmith, Christien, Robertson, Erik, Geschwind, Daniel

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Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study von Reiman, Eric M., Arboleda-Velasquez, Joseph F., Quiroz, Yakeel T., Huentelman, Matthew J., Beach, Thomas G., Caselli, Richard J., Chen, Yinghua, Su, Yi, Myers, Amanda J., Hardy, John, Paul Vonsattel, Jean, Younkin, Steven G., Bennett, David A., De Jager, Philip L., Larson, Eric B., Crane, Paul K., Keene, C. Dirk, Kamboh, M. Ilyas, Kofler, Julia K., Duque, Linda, Gilbert, John R., Gwirtsman, Harry E., Buxbaum, Joseph D., Dickson, Dennis W., Frosch, Matthew P., Ghetti, Bernardino F., Lunetta, Kathryn L., Wang, Li-San, Hyman, Bradley T., Kukull, Walter A., Foroud, Tatiana, Haines, Jonathan L., Mayeux, Richard P., Pericak-Vance, Margaret A., Schneider, Julie A., Trojanowski, John Q., Farrer, Lindsay A., Schellenberg, Gerard D., Beecham, Gary W., Montine, Thomas J., Jun, Gyungah R.

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Treatment of operable breast cancer in the elderly: a randomised clinical trial EORTC 10850 comparing modified radical mastectomy with tumorectomy plus tamoxifen von Fentiman, I.S, van Zijl, J, Karydas, I, Chaudary, M.A, Margreiter, R, Legrand, C, Therasse, P

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Evidence for in vivo synergism between docetaxel and gemcitabine in patients with metastatic breast cancer von Alexopoulos, A., Tryfonopoulos, D., Karamouzis, M. V., Gerasimidis, G., Karydas, I., Kandilis, K., Stavrakakis, J., Stavrinides, H., Georganta, C., Ardavanis, A., Rigatos, G.

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Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis von Kunkle, Brian W, Schmidt, Michael, Klein, Hans-Ulrich, Naj, Adam C, Hamilton-Nelson, Kara L, Larson, Eric B, Evans, Denis A, De Jager, Phil L, Crane, Paul K, Buxbaum, Joe D, Ertekin-Taner, Nilufer, Barnes, Lisa L, Fallin, M. Daniele, Manly, Jennifer J, Go, Rodney C. P, Obisesan, Thomas O, Kamboh, M. Ilyas, Bennett, David A, Hall, Kathleen S, Goate, Alison M, Foroud, Tatiana M, Martin, Eden R, Wang, Li-San, Byrd, Goldie S, Farrer, Lindsay A, Haines, Jonathan L, Schellenberg, Gerard D, Mayeux, Richard, Pericak-Vance, Margaret A, Reitz, Christiane, Graff-Radford, Neill R, Martinez, Izri, Ayodele, Temitope, Logue, Mark W, Cantwell, Laura B, Jean-Francois, Melissa, Kuzma, Amanda B, Adams, L.D, Vance, Jeffery M, Cuccaro, Michael L, Chung, Jaeyoon, Mez, Jesse, Lunetta, Kathryn L, Jun, Gyungah R, Lopez, Oscar L, Hendrie, Hugh C, Reiman, Eric M, Kowall, Neil W, Leverenz, James B, Small, Scott A, Levey, Allan I, Golde, Todd E, Saykin, Andrew J, Starks, Takiyah D, Albert, Marilyn S, Hyman, Bradley T, Petersen, Ronald C, Sano, Mary, Wisniewski, Thomas, Vassar, Robert, Kaye, Jeffrey A, Henderson, Victor W, DeCarli, Charles, LaFerla, Frank M, Brewer, James B, Miller, Bruce L, Swerdlow, Russell H, Van Eldik, Linda J, Paulson, Henry L, Trojanowski, John Q, Chui, Helena C, Rosenberg, Roger N, Craft, Suzanne, Grabowski, Thomas J, Asthana, Sanjay, Morris, John C, Strittmatter, Stephen M, Kukull, Walter A

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A novel Alzheimer disease locus located near the gene encoding tau protein von Jun, G, Ibrahim-Verbaas, C A, Vronskaya, M, Chung, J, Naj, A C, Kunkle, B W, Wang, L-S, Bis, J C, Bellenguez, C, Harold, D, Destefano, A L, Grenier-Boley, B, Sims, R, Smith, A V, Chouraki, V, Hamilton-Nelson, K L, Ikram, M A, Fievet, N, Martin, E R, Kamatani, Y, Valladares, O, Laza, A R, Zelenika, D, Choi, S-H, Boland, A, Becker, T, Kukull, W A, van der Lee, S J, Pasquier, F, Cruchaga, C, Beekly, D, Fitzpatrick, A L, Hanon, O, Gill, M, Gudnason, V, Campion, D, Love, S, Bennett, D A, Amin, N, Berr, C, Tsolaki, Magda, Buxbaum, J D, Lopez, O L, Deramecourt, V, Fox, N C, Cantwell, L B, Tárraga, L, Dufouil, C, Hardy, J, Crane, P K, Eiriksdottir, G, Hannequin, D, Clarke, R, Evans, D, Mosley, T H, Letenneur, L, Brayne, C, Maier, W, De Jager, P, Dartigues, J-F, Hampel, H, de Bruijn, R F A G, Tzourio, C, Pastor, P, Larson, E B, O'Donovan, M C, Montine, T J, Nalls, M A, Mead, S, Reiman, E M, Jonsson, P V, St George-Hyslop, P H, Boada, M, Passmore, P, Wendland, J R, Schmidt, R, Morgan, K, Powell, J F, Carasquillo, M, Jakobsdóttir, J, Kauwe, J S K, Rujescu, D, Nöthen, M M, Hofman, A, Jones, L, Haines, J L, Psaty, B M, Van Broeckhoven, C, Holmans, P, Launer, L J, Mayeux, R, Goate, A M, Escott-Price, V, Seshadri, S, Pericak-Vance, M A, Amouyel, P, Williams, J, van Duijn, C M, Schellenberg, G D, Farrer, L A

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Assessment of the genetic variance of late-onset Alzheimer’s disease von Ridge, Perry G, Hoyt, Kaitlyn B, Boehme, Kevin, Mukherjee, Shubhabrata, Crane, Paul K, Haines, Jonathan L, Mayeux, Richard, Farrer, Lindsay A, Pericak-Vance, Margaret A, Schellenberg, Gerard D, Kauwe, John S.K

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Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy von Müller, Ulrich, Schellenberg, Gerard D, Höglinger, Günter U, Melhem, Nadine M, Dickson, Dennis W, Sleiman, Patrick M A, Wang, Li-San, Klei, Lambertus, Rademakers, Rosa, de Silva, Rohan, Litvan, Irene, Riley, David E, van Swieten, John C, Heutink, Peter, Wszolek, Zbigniew K, Uitti, Ryan J, Vandrovcova, Jana, Hurtig, Howard I, Gross, Rachel G, Maetzler, Walter, Goldwurm, Stefano, Tolosa, Eduardo, Borroni, Barbara, Pastor, Pau, Cantwell, Laura B, Han, Mi Ryung, Dillman, Allissa, van der Brug, Marcel P, Gibbs, J Raphael, Cookson, Mark R, Hernandez, Dena G, Singleton, Andrew B, Farrer, Matthew J, Yu, Chang-En, Golbe, Lawrence I, Revesz, Tamas, Hardy, John, Lees, Andrew J, Devlin, Bernie, Hakonarson, Hakon

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A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies von Karch, Celeste M., Kao, Aimee W., Karydas, Anna, Onanuga, Khadijah, Martinez, Rita, Argouarch, Andrea, Wang, Chao, Huang, Cindy, Sohn, Peter Dongmin, Bowles, Kathryn R., Spina, Salvatore, Silva, M. Catarina, Marsh, Jacob A., Hsu, Simon, Pugh, Derian A., Ghoshal, Nupur, Norton, Joanne, Huang, Yadong, Lee, Suzee E., Seeley, William W., Theofilas, Panagiotis, Grinberg, Lea T., Moreno, Fermin, McIlroy, Kathryn, Boeve, Bradley F., Cairns, Nigel J., Crary, John F., Haggarty, Stephen J., Ichida, Justin K., Kosik, Kenneth S., Miller, Bruce L., Gan, Li, Goate, Alison M., Temple, Sally, Alquezar, Carolina, Bowles, Kathryn, Butler, David, Crary, John F., Gan, Li, Goate, Alison M., Hernandez, Israel, Hennes, Valerie, Huang, Cindy, Ichida, Justin K., Kampmann, Martin, Kao, Aimee W., Karch, Celeste M., Karydas, Anna, Kosik, Kenneth S., Martinez, Rita, Temple, Sally, Wang, Chao

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Variants in the ATP-Binding Cassette Transporter (ABCA7), Apolipoprotein E ϵ4,and the Risk of Late-Onset Alzheimer Disease in African Americans von Reitz, Christiane, Jun, Gyungah, Naj, Adam, Rajbhandary, Ruchita, Vardarajan, Badri Narayan, Wang, Li-San, Valladares, Otto, Lin, Chiao-Feng, Larson, Eric B, Graff-Radford, Neill R, Evans, Denis, De Jager, Philip L, Crane, Paul K, Buxbaum, Joseph D, Murrell, Jill R, Raj, Towfique, Ertekin-Taner, Nilufer, Logue, Mark, Baldwin, Clinton T, Green, Robert C, Barnes, Lisa L, Cantwell, Laura B, Fallin, M. Daniele, Go, Rodney C. P, Griffith, Patrick, Obisesan, Thomas O, Manly, Jennifer J, Lunetta, Kathryn L, Kamboh, M. Ilyas, Lopez, Oscar L, Bennett, David A, Hendrie, Hugh, Hall, Kathleen S, Goate, Alison M, Byrd, Goldie S, Kukull, Walter A, Foroud, Tatiana M, Haines, Jonathan L, Farrer, Lindsay A, Pericak-Vance, Margaret A, Schellenberg, Gerard D, Mayeux, Richard

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Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study von Østergaard, Søren D, Mukherjee, Shubhabrata, Sharp, Stephen J, Proitsi, Petroula, Lotta, Luca A, Day, Felix, Perry, John R B, Boehme, Kevin L, Walter, Stefan, Kauwe, John S, Gibbons, Laura E, Larson, Eric B, Powell, John F, Langenberg, Claudia, Crane, Paul K, Wareham, Nicholas J, Scott, Robert A

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Alzheimer's disease: analyzing the missing heritability von Ridge, Perry G, Mukherjee, Shubhabrata, Crane, Paul K, Kauwe, John S K

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Transethnic genome-wide scan identifies novel Alzheimer's disease loci von Jun, Gyungah R, Chung, Jaeyoon, Mez, Jesse, Barber, Robert, Beecham, Gary W, Bennett, David A, Buxbaum, Joseph D, Byrd, Goldie S, Carrasquillo, Minerva M, Crane, Paul K, Cruchaga, Carlos, De Jager, Philip, Ertekin-Taner, Nilufer, Evans, Denis, Fallin, M. Danielle, Foroud, Tatiana M, Friedland, Robert P, Goate, Alison M, Graff-Radford, Neill R, Hendrie, Hugh, Hall, Kathleen S, Hamilton-Nelson, Kara L, Inzelberg, Rivka, Kamboh, M. Ilyas, Kauwe, John S.K, Kukull, Walter A, Kunkle, Brian W, Kuwano, Ryozo, Larson, Eric B, Logue, Mark W, Manly, Jennifer J, Martin, Eden R, Montine, Thomas J, Mukherjee, Shubhabrata, Naj, Adam, Reiman, Eric M, Reitz, Christiane, Sherva, Richard, St. George-Hyslop, Peter H, Thornton, Timothy, Younkin, Steven G, Vardarajan, Badri N, Wang, Li-San, Wendlund, Jens R, Winslow, Ashley R, Haines, Jonathan, Mayeux, Richard, Pericak-Vance, Margaret A, Schellenberg, Gerard, Lunetta, Kathryn L, Farrer, Lindsay A

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Sex-specific genetic predictors of Alzheimer’s disease biomarkers von Deming, Yuetiva, Dumitrescu, Logan, Barnes, Lisa L., Thambisetty, Madhav, Kunkle, Brian, Gifford, Katherine A., Bush, William S., Chibnik, Lori B., Mukherjee, Shubhabrata, De Jager, Philip L., Kukull, Walter, Huentelman, Matt, Crane, Paul K., Resnick, Susan M., Keene, C. Dirk, Montine, Thomas J., Schellenberg, Gerard D., Haines, Jonathan L., Zetterberg, Henrik, Blennow, Kaj, Larson, Eric B., Johnson, Sterling C., Albert, Marilyn, Moghekar, Abhay, del Aguila, Jorge L., Fernandez, Maria Victoria, Budde, John, Hassenstab, Jason, Fagan, Anne M., Riemenschneider, Matthias, Petersen, Ronald C., Minthon, Lennart, Chao, Michael J., Van Deerlin, Vivianna M., Lee, Virginia M.-Y., Shaw, Leslie M., Trojanowski, John Q., Peskind, Elaine R., Li, Gail, Davis, Lea K., Sealock, Julia M., Cox, Nancy J., Goate, Alison M., Bennett, David A., Schneider, Julie A., Jefferson, Angela L., Cruchaga, Carlos, Hohman, Timothy J.

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Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis von Whitcomb, David C, LaRusch, Jessica, Krasinskas, Alyssa M, Klei, Lambertus, Smith, Jill P, Brand, Randall E, Neoptolemos, John P, Lerch, Markus M, Tector, Matt, Sandhu, Bimaljit S, Guda, Nalini M, Orlichenko, Lidiya, Alkaade, Samer, Amann, Stephen T, Anderson, Michelle A, Baillie, John, Banks, Peter A, Conwell, Darwin, Coté, Gregory A, Cotton, Peter B, DiSario, James, Farrer, Lindsay A, Forsmark, Chris E, Johnstone, Marianne, Gardner, Timothy B, Gelrud, Andres, Greenhalf, William, Haines, Jonathan L, Hartman, Douglas J, Hawes, Robert A, Lawrence, Christopher, Lewis, Michele, Mayerle, Julia, Mayeux, Richard, Melhem, Nadine M, Money, Mary E, Muniraj, Thiruvengadam, Papachristou, Georgios I, Pericak-Vance, Margaret A, Romagnuolo, Joseph, Schellenberg, Gerard D, Sherman, Stuart, Simon, Peter, Singh, Vijay P, Slivka, Adam, Stolz, Donna, Sutton, Robert, Weiss, Frank Ulrich, Wilcox, C Mel, Zarnescu, Narcis Octavian, Wisniewski, Stephen R, O'Connell, Michael R, Kienholz, Michelle L, Roeder, Kathryn, Barmada, M Michael, Yadav, Dhiraj, Devlin, Bernie

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SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians von Miyashita, Akinori, Koike, Asako, Jun, Gyungah, Wang, Li-San, Takahashi, Satoshi, Matsubara, Etsuro, Kawarabayashi, Takeshi, Shoji, Mikio, Tomita, Naoki, Arai, Hiroyuki, Asada, Takashi, Harigaya, Yasuo, Ikeda, Masaki, Amari, Masakuni, Hanyu, Haruo, Higuchi, Susumu, Ikeuchi, Takeshi, Nishizawa, Masatoyo, Suga, Masaichi, Kawase, Yasuhiro, Akatsu, Hiroyasu, Kosaka, Kenji, Yamamoto, Takayuki, Imagawa, Masaki, Hamaguchi, Tsuyoshi, Yamada, Masahito, Morihara, Takashi, Moriaha, Takashi, Takeda, Masatoshi, Takao, Takeo, Nakata, Kenji, Fujisawa, Yoshikatsu, Sasaki, Ken, Watanabe, Ken, Nakashima, Kenji, Urakami, Katsuya, Ooya, Terumi, Takahashi, Mitsuo, Yuzuriha, Takefumi, Serikawa, Kayoko, Yoshimoto, Seishi, Nakagawa, Ryuji, Kim, Jong-Won, Ki, Chang-Seok, Won, Hong-Hee, Na, Duk L, Seo, Sang Won, Mook-Jung, Inhee, St George-Hyslop, Peter, Mayeux, Richard, Haines, Jonathan L, Pericak-Vance, Margaret A, Yoshida, Makiko, Nishida, Nao, Tokunaga, Katsushi, Yamamoto, Ken, Tsuji, Shoji, Kanazawa, Ichiro, Ihara, Yasuo, Schellenberg, Gerard D, Farrer, Lindsay A, Kuwano, Ryozo

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Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci von Karch, Celeste M, Ezerskiy, Lubov A, Bertelsen, Sarah, Goate, Alison M

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Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants von Zou, Fanggeng, Chai, High Seng, Younkin, Curtis S, Allen, Mariet, Crook, Julia, Pankratz, V Shane, Carrasquillo, Minerva M, Rowley, Christopher N, Nair, Asha A, Middha, Sumit, Maharjan, Sooraj, Nguyen, Thuy, Ma, Li, Malphrus, Kimberly G, Palusak, Ryan, Lincoln, Sarah, Bisceglio, Gina, Georgescu, Constantin, Kouri, Naomi, Kolbert, Christopher P, Jen, Jin, Haines, Jonathan L, Mayeux, Richard, Pericak-Vance, Margaret A, Farrer, Lindsay A, Schellenberg, Gerard D, Petersen, Ronald C, Graff-Radford, Neill R, Dickson, Dennis W, Younkin, Steven G, Ertekin-Taner, Nilüfer

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Amyloid-β predominant Alzheimer's disease neuropathologic change von Kovacs, Gabor G, Katsumata, Yuriko, Wu, Xian, Aung, Khine Zin, Fardo, David W, Forrest, Shelley L, Nelson, Peter T

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