A novel B-domain O-glycoPEGylated FVIII (N8-GP) demonstrates full efficacy and prolonged effect in hemophilic mice models von Stennicke, Henning R., Kjalke, Marianne, Karpf, Ditte M., Balling, Kristoffer W., Johansen, Peter B., Elm, Torben, Øvlisen, Kristine, Möller, Flemming, Holmberg, Heidi L., Gudme, Charlotte N., Persson, Egon, Hilden, Ida, Pelzer, Hermann, Rahbek-Nielsen, Henrik, Jespersgaard, Christina, Bogsnes, Are, Pedersen, Anette A., Kristensen, Anne K., Peschke, Bernd, Kappers, Wendy, Rode, Frederik, Thim, Lars, Tranholm, Mikael, Ezban, Mirella, Olsen, Eva H.N., Bjørn, Søren E.

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New, Azide-Free Transformation of Epoxides into 1,2-Diamino Compounds:  Synthesis of the Anti-Influenza Neuraminidase Inhibitor Oseltamivir Phosphate (Tamiflu) von Karpf, Martin, Trussardi, René

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Clinical studies with oral lipid based formulations of poorly soluble compounds von Fatouros, Dimitrios G, Karpf, Ditte M, Nielsen, Flemming S, Mullertz, Anette

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Plasma elimination kinetics for factor VII are independent of its activation to factor VIIa and complex formation with plasma inhibitors von Petersen, Lars C., Elm, Torben, Ezban, Mirella, Krogh, Thomas N., Karpf, Ditte M., Steinø, Anne, Olsen, Eva H. N., Sørensen, Brit B.

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In vivo clearance and metabolism of recombinant activated factor VII (rFVIIa) and its complexes with plasma protease inhibitors in the liver von Seested, T, Appa, R.S, Christensen, E.I, Ioannou, Y.A, Krogh, T.N, Karpf, D.M, Nielsen, H.M

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Preclinical pharmacokinetics and biodistribution of subcutaneously administered glycoPEGylated recombinant factor VIII (N8‐GP) and development of a human pharmacokinetic prediction... von Rode, F., Almholt, K., Petersen, M., Kreilgaard, M., Kjalke, M., Karpf, D. M., Groth, A. V., Johansen, P. B., Larsen, L. F., Loftager, M., Haaning, J.

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Factor VIII with a 237 amino acid B‐domain has an extended half‐life in F8‐knockout mice von Bloem, E., Karpf, D. M., Nørby, P. L., Johansen, P. B., Loftager, M., Rahbek‐Nielsen, H., Petersen, H. H., Blouse, G. E., Thim, L., Kjalke, M., Bolt, G.

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High‐affinity von Willebrand factor binding does not affect the anatomical or hepatocellular distribution of factor VIII in rats von Øie, C. I., Roepstorff, K., Behrens, C., Bøggild Kristensen, J., Karpf, D. M., Bolt, G., Gudme, C. N., Kjalke, M., Smedsrød, B., Appa, R. S.

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Hyperglycosylation prolongs the circulation of coagulation factor IX von BOLT, G., BJELKE, J. R., HERMIT, M. B., HANSEN, L., KARPF, D. M., KRISTENSEN, C.

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Activation peptides prolong the murine plasma half-life of human factor VII von Johansson, Linda, Karpf, Ditte M., Hansen, Lene, Pelzer, Hermann, Persson, Egon

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Pharmacokinetics and pharmacodynamics of a new recombinant FVIII (N8) in haemophilia A mice von ELM, T., KARPF, D. M., ØVLISEN, K., PELZER, H., EZBAN, M., KJALKE, M., TRANHOLM, M.

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Influence of the type of surfactant and the degree of dispersion on the lymphatic transport of halofantrine in conscious rats von Karpf, Ditte M, Holm, René, Kristensen, Henning G, Müllertz, Anette

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Effect of different surfactants in biorelevant medium on the secretion of a lipophilic compound in lipoproteins using Caco-2 cell culture von Karpf, Ditte M., Holm, René, Garafalo, Carole, Levy, Emile, Jacobsen, Jette, Müllertz, Anette

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Intravascular inhibition of factor VIIa and the analogue NN1731 by antithrombin von Petersen, Lars C., Karpf, Ditte M., Agersø, Henrik, Hermit, Mette B., Pelzer, Hermann, Persson, Egon, Nichols, Timothy C., Ezban, Mirella

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Pharmacokinetics and ex vivo whole blood clot formation of a new recombinant FVIII (N8) in haemophilia A dogs von KARPF, D. M., KJALKE, M., THIM, L., AGERSØ, H., MERRICKS, E. P., DEFRIESS, N., NICHOLS, T. C., EZBAN, M.

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Prolonged half-life of glycoPEGylated rFVIIa variants compared to native rFVIIa von Karpf, Ditte M, Sørensen, Brit B, Hermit, Mette B, Holmberg, Heidi L, Tranholm, Mikael, Bysted, Britta V, Groth, Andreas V, Bjørn, Søren E, Stennicke, Henning R

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The Synthetic Development of the Anti-Influenza Neuraminidase Inhibitor Oseltamivir Phosphate (Tamiflu®): A Challenge for Synthesis & Process Research von Abrecht, Stefan, Harrington, Peter, Iding, Hans, Karpf, Martin, Trussardi, René, Wirz, Beat, Zutter, Ulrich

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Perinatal complications and long-term neurodevelopmental outcome of infants with intrauterine growth restriction von von Beckerath, Anne-Karen, Kollmann, Martina, MD, Rotky-Fast, Christa, MD, Karpf, Eva, MD, Lang, Uwe, MD, PhD, Klaritsch, Philipp, MD

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Effect of ketoprofen and its enantiomers on the renal disposition of methotrexate in the isolated perfused rat kidney von Karpf, D. M., Kirkegaard, A. L., Evans, A. M., Nation, R. L., Hayball, P. J., Milne, R. W.

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Symptoms and Microenvironmental Measures in Nonproblem Buildings von Hodgson, Michael J., Frohliger, John, Permar, Edward, Tidwell, Cecilia, Traven, Neal D., Olenchock, Stephen A., Karpf, Michael

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