DNA Demethylation in Zebrafish Involves the Coupling of a Deaminase, a Glycosylase, and Gadd45 von Rai, Kunal, Huggins, Ian J., James, Smitha R., Karpf, Adam R., Jones, David A., Cairns, Bradley R.

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Inhibition of miR-328-3p Impairs Cancer Stem Cell Function and Prevents Metastasis in Ovarian Cancer von Srivastava, Amit K, Banerjee, Ananya, Cui, Tiantian, Han, Chunhua, Cai, Shurui, Liu, Lu, Wu, Dayong, Cui, Ri, Li, Zaibo, Zhang, Xiaoli, Xie, Guozhen, Selvendiran, Karuppaiyah, Patnaik, Srinivas, Karpf, Adam R, Liu, Jinsong, Cohn, David E, Wang, Qi-En

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PROTACs in Ovarian Cancer: Current Advancements and Future Perspectives von Vorderbruggen, Makenzie, Velázquez-Martínez, Carlos A, Natarajan, Amarnath, Karpf, Adam R

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Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication von Estève, Pierre-Olivier, Chin, Hang Gyeong, Smallwood, Andrea, Feehery, George R, Gangisetty, Omkaram, Karpf, Adam R, Carey, Michael F, Pradhan, Sriharsa

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Genetic disruption of cytosine DNA methyltransferase enzymes induces chromosomal instability in human cancer cells von KARPF, Adam R, MATSUI, Sei-Ichi

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In vivo modeling of metastatic human high-grade serous ovarian cancer in mice von Kim, Olga, Park, Eun Young, Klinkebiel, David L., Pack, Svetlana D., Shin, Yong-Hyun, Abdullaev, Zied, Emerson, Robert E., Coffey, Donna M., Kwon, Sun Young, Creighton, Chad J., Kwon, Sanghoon, Chang, Edmund C., Chiang, Theodore, Yatsenko, Alexander N., Chien, Jeremy, Cheon, Dong-Joo, Yang-Hartwich, Yang, Nakshatri, Harikrishna, Nephew, Kenneth P., Behringer, Richard R., Fernandez, Facundo M., Cho, Chi-Heum, Vanderhyden, Barbara, Drapkin, Ronny, Bast, Robert C., Miller, Kathy D., Karpf, Adam R., Kim, Jaeyeon

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Targeting progesterone signaling prevents metastatic ovarian cancer von Kim, Olga, Park, Eun Young, Kwon, Sun Young, Shin, Sojin, Emerson, Robert E., Shin, Yong-Hyun, DeMayo, Francesco J., Lydon, John P., Coffey, Donna M., Hawkins, Shannon M., Quilliam, Lawrence A., Cheon, Dong-Joo, Fernández, Facundo M., Nephew, Kenneth P., Karpf, Adam R., Widschwendter, Martin, Sood, Anil K., Bast, Robert C., Godwin, Andrew K., Miller, Kathy D., Cho, Chi-Heum, Kim, Jaeyeon

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Co-regulation and function of FOXM1/RHNO1 bidirectional genes in cancer von Barger, Carter J., Chee, Linda, Albahrani, Mustafa, Munoz-Trujillo, Catalina, Boghean, Lidia, Branick, Connor, Odunsi, Kunle, Drapkin, Ronny, Zou, Lee, Karpf, Adam R.

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Association between global DNA hypomethylation in leukocytes and risk of breast cancer von Choi, Ji-Yeob, James, Smitha R., Link, Petra A., McCann, Susan E., Hong, Chi-Chen, Davis, Warren, Nesline, Mary K., Ambrosone, Christine B., Karpf, Adam R.

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Epigenetic Potentiation of NY-ESO-1 Vaccine Therapy in Human Ovarian Cancer von ODUNSI, Kunle, MATSUZAKI, Junko, BECK, Amy, BATT, Carl A, RITTER, Gerd, LELE, Shashikant, GNJATIC, Sacha, KARPF, Adam R, JAMES, Smitha R, MHAWECH-FAUCEGLIA, Paulette, TSUJI, Takemasa, MILLER, Austin, WA ZHANG, AKERS, Stacey N, GRIFFITHS, Elizabeth A, MILIOTTO, Anthony

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Genetic determinants of FOXM1 overexpression in epithelial ovarian cancer and functional contribution to cell cycle progression von Barger, Carter J, Zhang, Wa, Hillman, Joanna, Stablewski, Aimee B, Higgins, Michael J, Vanderhyden, Barbara C, Odunsi, Kunle, Karpf, Adam R

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Dnmt3 and G9a Cooperate for Tissue-specific Development in Zebrafish von Rai, Kunal, Jafri, Itrat F, Chidester, Stephanie, James, Smitha R, Karpf, Adam R, Cairns, Bradley R, Jones, David A

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Promoter Hypomethylation and Expression Is Conserved in Mouse Chronic Lymphocytic Leukemia Induced by Decreased or Inactivated Dnmt3a von Haney, Staci L., Upchurch, G. Michael, Opavska, Jana, Klinkebiel, David, Hlady, Ryan A., Suresh, Abhinav, Pirruccello, Samuel J., Shukla, Vipul, Lu, Runqing, Costinean, Stefan, Rizzino, Angie, Karpf, Adam R., Joshi, Shantaram, Swanson, Patrick, Opavsky, Rene

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Epigenetic activation of POTE genes in ovarian cancer von Sharma, Ashok, Albahrani, Mustafa, Zhang, Wa, Kufel, Christina N., James, Smitha R., Odunsi, Kunle, Klinkebiel, David, Karpf, Adam R.

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Immunomodulatory action of the DNA methyltransferase inhibitor SGI-110 in epithelial ovarian cancer cells and xenografts von Srivastava, Pragya, Paluch, Benjamin E, Matsuzaki, Junko, James, Smitha R, Collamat-Lai, Golda, Taverna, Pietro, Karpf, Adam R, Griffiths, Elizabeth A

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Reactivating the expression of methylation silenced genes in human cancer von Karpf, Adam R, Jones, David A

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Specific Method for the Determination of Genomic DNA Methylation by Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry von Song, Liguo, James, Smitha R, Kazim, Latif, Karpf, Adam R

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NB compounds are potent and efficacious FOXM1 inhibitors in high-grade serous ovarian cancer cells von Liu, Cassie, Vorderbruggen, Makenzie, Muñoz-Trujillo, Catalina, Kim, Sung Hoon, Katzenellenbogen, John A, Katzenellenbogen, Benita S, Karpf, Adam R

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Induction of cancer testis antigen expression in circulating acute myeloid leukemia blasts following hypomethylating agent monotherapy von Srivastava, Pragya, Paluch, Benjamin E, Matsuzaki, Junko, James, Smitha R, Collamat-Lai, Golda, Blagitko-Dorfs, Nadja, Ford, Laurie Ann, Naqash, Rafeh, Lübbert, Michael, Karpf, Adam R, Nemeth, Michael J, Griffiths, Elizabeth A

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Essential Role for Dnmt1 in the Prevention and Maintenance of MYC-Induced T-Cell Lymphomas von Peters, Staci L., Hlady, Ryan A., Opavska, Jana, Klinkebiel, David, Novakova, Slavomira, Smith, Lynette M., Lewis, Robert E., Karpf, Adam R., Simpson, Melanie A., Wu, Lizhao, Opavsky, Rene

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