Preparation of transdermal monolithic systems of indapamide by solvent casting method and the use of vegetable oils as permeation enhancer von Sanap, GS, Dama, GY, Hande, AS, Karpe, SP, Nalawade, SV, Kakade, RS, Jadhav, UY

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Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling von Van Vliet, NA, Bos, MM, Thesing, CS, Chaker, L, Pietzner, M, Houtman, E, Neville, MJ, Li-Gao, R, Trompet, S, Mustafa, R, Ahmadizar, F, Beekman, M, Bot, M, Budde, K, Christodoulides, C, Dehghan, A, Delles, C, Elliott, P, Evangelou, M, Gao, H, Ghanbari, M, Van Herwaarden, AE, Ikram, MA, Jaeger, M, Jukema, JW, Karaman, I, Karpe, F, Kloppenburg, M, Meessen, JMTA, Meulenbelt, I, Milaneschi, Y, Mooijaart, SP, Mook-Kanamori, DO, Netea, MG, Netea-Maier, RT, Peeters, RP, Penninx, BWJH, Sattar, N, Slagboom, PE, Suchiman, HED, Volzke, H, Willems van Dijk, K, Noordam, R, Van Heemst, D

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A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk von Fontanillas, P, Rivas, MA, Locke, AE, Isomaa, B, Meitinger, T, Deloukas, P, Stirrups, KE, Owen, KR, Frayling, TM, Levy, JC, Hodgkiss, D, Hattersley, AT, Kuulasmaa, T, Puppala, S, Teslovich, TM, Donnelly, PJ, Ebrahim, SB, Kumar, S, Jia, W, Ma, RC, Sandhu, M, Scott, J, Sladek, R, Tandon, N, Zeggini, E, Watanabe, RM, Koistinen, HA, Collins, FS, Karpe, F, Hansen, T, Kuusisto, J, Hale, DE, Duggirala, R, Hanis, CL, Mohlke, KL, Boehnke, M, Hartl, C, Gloyn, AL, Kumar, A, Ladenvall, C, Scott, LJ, Jula, A, Palotie, A, Jacobs, SB, Wessel, J, Buck, G, Buck, D, Gjesing, AP, Jackson, AU, Jun, G, Justesen, JM, Neville, M, Onofrio, R, Small, KS, Stringham, HM, Trakalo, J, Carneiro, MO, DePristo, M, Grant, G, Poplin, R, Purcell, S, Palmer, ND, Lakka, TA, Langenberg, C, Franks, PW, Ng, MC, Rolandsson, O, Bowden, DW, Mägi, R, Metspalu, A, Narisu, N, Kinnunen, L, Bonnycastle, LL, Pasko, D, Wood, AR, Fadista, J, Pollin, TI, Atzmon, G, Müller-Nurasyid, M, Wu, Y, Illig, T, Meisinger, C, Musani, SK, Taylor, HA, Correa, A, Oksa, H, Scott, WR, Afzal, U, Kooner, JS, Fuchsberger, C, Lee, JY, Huang, J, Melander, O, Below, JE, Lim, WY, Cheng, CY, Chan, E, Tai, ES, Gaulton, KJ, Linneberg, A

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Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci von Erzurumluoglu, AM, Liu, M, Jackson, VE, Barnes, DR, Datta, G, Melbourne, CA, Batini, C, Jiang, T, Agrawal, A, Bertelsen, S, Boehnke, M, Bots, ML, Brazel, DM, Chambers, JC, Chen, C, Corley, J, Chou, Y-L, David, SP, de Leeuw, CA, Dennis, JG, Dominiczak, AF, Eaton, C, Elliott, P, Evangelou, E, Foroud, T, Goate, A, Haessler, J, Hammerschlag, AR, Harris, SE, Hattersley, A, Heath, A, Hsu, C, Kanoni, S, Kapoor, M, Kardia, SL, Kontto, J, Kooperberg, C, Kuulasmaa, K, Laakso, M, Lai, D, Le, N, Loukola, A, Luan, J, Mangino, M, Marioni, RE, Marouli, E, Martin, NG, McGue, M, Michailidou, K, Mihailov, E, Moitry, M, Naheed, A, Nauck, M, Polderman, TJ, Rasheed, A, Rice, J, Samani, NJ, Samuel, M, Schlessinger, D, Scholte, SH, Scott, RA, Starr, JM, Stirrups, K, Tardif, J-C, Thompson, DJ, Tindle, HA, Tragante, V, Trompet, S, Varga, TV, Warren, HR, Weir, DR, Wetherill, L, Yavas, E, Zhan, X, Zhang, W, Zhao, W, Zhou, K, Amouyel, P, Blankenberg, S, Chowdhury, R, Deary, IJ, Di Angelantonio, E, Ferrières, J, Frayling, TM, Frossard, P, Hall, IP, Jukema, JW, Metspalu, A, Palmer, CNA, Salomaa, V, Sattar, N, Spector, T, Strachan, DP, Saleheen, D, Wain, LV, Abecasis, GR, Danesh, J, Tobin, MD, Vrieze, S, Howson, JMM

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A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk von Fontanillas, P, Rivas, MA, Locke, AE, Wu, Y, Fuchsberger, C, Im, HK, Blackwell, TW, Chen, Y, Green, T, Ma, C, Pearson, RD, Perry, JRB, Eriksson, JG, Palotie, A, Goodarzi, MO, Blancher, C, Jackson, AU, Justesen, JM, Neville, M, Stringham, HM, Trakalo, J, Carneiro, MO, Fennell, T, Goldstein, JI, Hrabé de Angelis, M, Poplin, R, Schwarzmayr, T, Shakir, K, Doney, ASF, Varga, TV, Rolandsson, O, Rosengren, AH, Farook, VS, Thameem, F, Puppala, S, Kumar, S, Jenkinson, CP, Curran, JE, Abboud, HE, Syvänen, A-C, Hicks, PJ, Palmer, ND, Ng, MCY, Bowden, DW, Esko, T, Metspalu, A, Kinnunen, L, Barzilai, N, Thorand, B, Strauch, K, Peters, A, Roden, M, Kriebel, J, Lannfelt, L, Wilson, G, Correa, A, Scott, WR, Afzal, U, Kooner, JS, Cho, YS, Han, B-G, Käräjämäki, A, Huang, J, Melander, O, Orho-Melander, M, Below, JE, Chan, E, Tai, ES, Aung, T, Tuomi, T, Kravic, J, Lauritzen, T, Deloukas, P, Owen, KR, Farmer, AJ, Frayling, TM, O'Rahilly, SP, Levy, JC, Barroso, I, Daly, MJ, Ebrahim, SB, Elliott, P, Froguel, P, Hu, C, Jia, W, McVean, G, Teo, YY, Zeggini, E, Koistinen, HA, Salomaa, V, Prokopenko, I, Morris, AD, Lind, L, Groop, L, Hansen, T, Duggirala, R, Wilson, JG, Mohlke, KL, Boehnke, M, Gloyn, AL

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