Targeting the CD40-CD40L pathway in autoimmune diseases: Humoral immunity and beyond von Karnell, Jodi L., Rieder, Sadiye Amcaoglu, Ettinger, Rachel, Kolbeck, Roland

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Role of CD11c+ T-bet+ B cells in human health and disease von Karnell, Jodi L., Kumar, Varsha, Wang, Jingya, Wang, Shu, Voynova, Elisaveta, Ettinger, Rachel

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In or out of control: Modulating regulatory T cell homeostasis and function with immune checkpoint pathways von Abdeladhim, Maha, Karnell, Jodi L, Rieder, Sadiye Amcaoglu

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Oligodendrocyte precursor cells present antigen and are cytotoxic targets in inflammatory demyelination von Kirby, Leslie, Jin, Jing, Cardona, Jaime Gonzalez, Smith, Matthew D., Martin, Kyle A., Wang, Jingya, Strasburger, Hayley, Herbst, Leyla, Alexis, Maya, Karnell, Jodi, Davidson, Todd, Dutta, Ranjan, Goverman, Joan, Bergles, Dwight, Calabresi, Peter A.

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Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models von Panda, Santosh K, Facchinetti, Valeria, Voynova, Elisaveta, Hanabuchi, Shino, Karnell, Jodi L, Hanna, Richard N, Kolbeck, Roland, Sanjuan, Miguel A, Ettinger, Rachel, Liu, Yong-Jun

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Quetiapine has an additive effect to triiodothyronine in inducing differentiation of oligodendrocyte precursor cells through induction of cholesterol biosynthesis von Gonzalez Cardona, Jaime, Smith, Matthew D, Wang, Jingya, Kirby, Leslie, Schott, Jason T, Davidson, Todd, Karnell, Jodi L, Whartenby, Katharine A, Calabresi, Peter A

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Self-reactive IgE exacerbates interferon responses associated with autoimmunity von Henault, Jill, Riggs, Jeffrey M, Karnell, Jodi L, Liarski, Vladimir M, Li, Jianqing, Shirinian, Lena, Xu, Linda, Casey, Kerry A, Smith, Michael A, Khatry, Deepak B, Izhak, Liat, Clarke, Lorraine, Herbst, Ronald, Ettinger, Rachel, Petri, Michelle, Clark, Marcus R, Mustelin, Tomas, Kolbeck, Roland, Sanjuan, Miguel A

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B7-H7 (HHLA2) inhibits T-cell activation and proliferation in the presence of TCR and CD28 signaling von Rieder, Sadiye Amcaoglu, Wang, Jingya, White, Natalie, Qadri, Ariful, Menard, Catherine, Stephens, Geoffrey, Karnell, Jodi L., Rudd, Christopher E., Kolbeck, Roland

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Mycophenolic acid differentially impacts B cell function depending on the stage of differentiation von Karnell, Jodi L, Karnell, 3rd, Fredrick G, Stephens, Geoffrey L, Rajan, Bhargavi, Morehouse, Chris, Li, Ying, Swerdlow, Bonnie, Wilson, Mildred, Goldbach-Mansky, Raphaela, Groves, Christopher, Coyle, Anthony J, Herbst, Ronald, Ettinger, Rachel

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Discovery and characterization of potent IL-21 neutralizing antibodies via a novel alternating antigen immunization and humanization strategy von Varkey, Reena, Du, Qun, Karnell, Jodi L, Xiao, Xiaodong, Casey, Kerry A, Woods, Rob, Rosenthal, Kim, Wilson, Susan, Dall'Acqua, William F, Wu, Herren, Herbst, Ronald, Ettinger, Rachel, Damschroder, Melissa

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Effects of CXCL13 inhibition on lymphoid follicles in models of autoimmune disease von Finch, Donna K., Ettinger, Rachel, Karnell, Jodi L., Herbst, Ronald, Sleeman, Matthew A.

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CD19 and CD32b differentially regulate human B cell responsiveness von Karnell, Jodi L, Dimasi, Nazzareno, Karnell, 3rd, Fredrick G, Fleming, Ryan, Kuta, Ellen, Wilson, Mildred, Wu, Herren, Gao, Changshou, Herbst, Ronald, Ettinger, Rachel

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Discerning the kinetics of autoimmune manifestations in a model of Sjögren's syndrome von Karnell, Jodi L, Mahmoud, Tamer I, Herbst, Ronald, Ettinger, Rachel

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SLE Plasma Profiling Identifies Unique Signatures of Lupus Nephritis and Discoid Lupus von Smith, Michael A., Henault, Jill, Karnell, Jodi L., Parker, Melissa L., Riggs, Jeffrey M., Sinibaldi, Dominic, Taylor, Devon K., Ettinger, Rachel, Grant, Ethan P., Sanjuan, Miguel A., Kolbeck, Roland, Petri, Michelle A., Casey, Kerry A.

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Characterisation of anifrolumab, a fully human anti-interferon receptor antagonist antibody for the treatment of systemic lupus erythematosus von Riggs, Jeffrey M, Hanna, Richard N, Rajan, Bhargavi, Zerrouki, Kamelia, Karnell, Jodi L, Sagar, Divya, Vainshtein, Inna, Farmer, Erika, Rosenthal, Kimberly, Morehouse, Chris, de los Reyes, Melissa, Schifferli, Kevin, Liang, Meina, Sanjuan, Miguel A, Sims, Gary P, Kolbeck, Roland

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The Interplay of IL-21 and BAFF in the Formation and Maintenance of Human B Cell Memory von Karnell, Jodi L, Ettinger, Rachel

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IL-21 drives expansion and plasma cell differentiation of autoreactive CD11chiT-bet+ B cells in SLE von Wang, Shu, Wang, Jingya, Kumar, Varsha, Karnell, Jodi L., Naiman, Brian, Gross, Phillip S., Rahman, Saifur, Zerrouki, Kamelia, Hanna, Richard, Morehouse, Christopher, Holoweckyj, Nicholas, Liu, Hao, Manna, Zerai, Goldbach-Mansky, Raphaela, Hasni, Sarfaraz, Siegel, Richard, Sanjuan, Miguel, Streicher, Katie, Cancro, Michael P., Kolbeck, Roland, Ettinger, Rachel

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Distinct roles for PTEN in prevention of T cell lymphoma and autoimmunity in mice von Liu, Xiaohe, Karnell, Jodi L, Yin, Bu, Zhang, Ruan, Zhang, Jidong, Li, Peiying, Choi, Yongwon, Maltzman, Jonathan S, Pear, Warren S, Bassing, Craig H, Turka, Laurence A

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Comprehensive proteomic profiling of Sjogren’s syndrome revealed dysregulation of interferon and other immunologic pathways von Wang, Jingya, Wang, Shu, Rahman, Saifur, Kumar, Varsha, Karnell, Jodi L., Voynova, Elisaveta Ninova, Sanjuan, Miguel A, Kolbeck, Roland, Alevizos, Ilias, Ettinger, Rachel

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Regulation of CD4+ T-cell responses by PTEN von Karnell, Jodi Lea

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