T Cell Exit from Quiescence and Differentiation into Th2 Cells Depend on Raptor-mTORC1-Mediated Metabolic Reprogramming von Yang, Kai, Shrestha, Sharad, Zeng, Hu, Karmaus, Peer W.F., Neale, Geoffrey, Vogel, Peter, Guertin, David A., Lamb, Richard F., Chi, Hongbo

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Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells von Du, Xingrong, Wen, Jing, Wang, Yanyan, Karmaus, Peer W. F., Khatamian, Alireza, Tan, Haiyan, Li, Yuxin, Guy, Cliff, Nguyen, Thanh-Long M., Dhungana, Yogesh, Neale, Geoffrey, Peng, Junmin, Yu, Jiyang, Chi, Hongbo

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Histone crotonylation promotes mesoendodermal commitment of human embryonic stem cells von Fang, Yi, Xu, Xiaojiang, Ding, Jun, Yang, Lu, Doan, Mary T., Karmaus, Peer W.F., Snyder, Nathaniel W., Zhao, Yingming, Li, Jian-Liang, Li, Xiaoling

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Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity von Karmaus, Peer W. F., Chen, Xiang, Lim, Seon Ah, Herrada, Andrés A., Nguyen, Thanh-Long M., Xu, Beisi, Dhungana, Yogesh, Rankin, Sherri, Chen, Wenan, Rosencrance, Celeste, Yang, Kai, Fan, Yiping, Cheng, Yong, Easton, John, Neale, Geoffrey, Vogel, Peter, Chi, Hongbo

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Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF-mediated myelopoiesis von Karmaus, Peer W F, Herrada, Andrés A, Guy, Cliff, Neale, Geoffrey, Dhungana, Yogesh, Long, Lingyun, Vogel, Peter, Avila, Julian, Clish, Clary B, Chi, Hongbo

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mTOR and metabolic regulation of conventional and regulatory T cells von Liu, Chaohong, Chapman, Nicole M., Karmaus, Peer W. F., Zeng, Hu, Chi, Hongbo

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Challenges for Integrating Immunotoxicology into the Twenty-First-Century Toxicology Testing Paradigm von Karmaus, Peer W. F., Karmaus, Agnes L.

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Race-specific association of an IRGM risk allele with cytokine expression in human subjects von Ajayi, Teminioluwa, Rai, Prashant, Shi, Min, Gabor, Kristin A., Karmaus, Peer W. F., Meacham, Julie M., Katen, Kevin, Madenspacher, Jennifer H., Schurman, Shepherd H., Fessler, Michael B.

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Tsc1 promotes the differentiation of memory CD8⁺ T cells via orchestrating the transcriptional and metabolic programs von Shrestha, Sharad, Yang, Kai, Wei, Jun, Karmaus, Peer W. F., Neale, Geoffrey, Chi, Hongbo

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Meta-Analysis of COVID-19 BAL Single-Cell RNA Sequencing Reveals Alveolar Epithelial Transitions and Unique Alveolar Epithelial Cell Fates von Karmaus, Peer W F, Tata, Aleksandra, Meacham, Julie M, Day, Frank, Thrower, David, Tata, Purushothama Rao, Fessler, Michael B

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CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation von Izumi, Gentaro, Nakano, Hideki, Nakano, Keiko, Whitehead, Gregory S., Grimm, Sara A., Fessler, Michael B., Karmaus, Peer W., Cook, Donald N.

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IRGM1 links mitochondrial quality control to autoimmunity von Rai, Prashant, Janardhan, Kyathanahalli S., Meacham, Julie, Madenspacher, Jennifer H., Lin, Wan-Chi, Karmaus, Peer W. F., Martinez, Jennifer, Li, Quan-Zhen, Yan, Mei, Zeng, Jialiu, Grinstaff, Mark W., Shirihai, Orian S., Taylor, Gregory A., Fessler, Michael B.

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Application of single cell methods in immunometabolism and immunotoxicology von Karmaus, Peer W.F.

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Oxidized Low-Density Lipoprotein Accumulation Suppresses Glycolysis and Attenuates the Macrophage Inflammatory Response by Diverting Transcription from the HIF-1α to the Nrf2 Pathw... von Ting, Kenneth K Y, Yu, Pei, Dow, Riley, Floro, Eric, Ibrahim, Hisham, Scipione, Corey A, Hyduk, Sharon J, Polenz, Chanele K, Zaslaver, Olga, Karmaus, Peer W F, Fessler, Michael B, Röst, Hannes L, Ohh, Michael, Tsai, Sue, Winer, Daniel A, Woo, Minna, Rocheleau, Jonathan, Jongstra-Bilen, Jenny, Cybulsky, Myron I

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Genetic dissection of dendritic cell homeostasis and function: lessons from cell type-specific gene ablation von Karmaus, Peer W. F, Chi, Hongbo

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CD9 and Aryl Hydrocarbon Receptor Are Markers of Human CD19+CD14+ Atypical B Cells and Are Dysregulated in Systemic Lupus Erythematous Disease von Blevins, Lance K, Khan, D M Isha Olive, Crawford, Robert B, O'Neill, Christine, Bach, Anthony P, Zhou, Jiajun, Karmaus, Peer W, Ang, Dennis C, Thapa, Rupak, Kaminski, Norbert E

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Race/ethnicity-stratified fine-mapping of the MHC locus reveals genetic variants associated with late-onset asthma von Lee, Eunice Y, Choi, Wonson, Burkholder, Adam B, Perera, Lalith, Mack, Jasmine A, Miller, Frederick W, Fessler, Michael B, Cook, Donald N, Karmaus, Peer W F, Nakano, Hideki, Garantziotis, Stavros, Madenspacher, Jennifer H, House, John S, Akhtari, Farida S, Schmitt, Charles S, Fargo, David C, Hall, Janet E, Motsinger-Reif, Alison A

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Untargeted lipidomics reveals novel HDL metabotypes and lipid-clinical correlates von Karmaus, Peer W.F., Gordon, Scott M., Chen, Marcus Y., Motsinger-Reif, Alison A., Snyder, Rodney W., Fennell, Timothy R., Waidyanatha, Suramya, Fernando, Reshan A., Remaley, Alan T., Fessler, Michael B.

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Cholesterol biosynthesis modulates differentiation in murine cranial neural crest cells von Pascual, Florencia, Icyuz, Mert, Karmaus, Peer, Brooks, Ashley, Van Gorder, Elizabeth, Fessler, Michael B., Shaw, Natalie D.

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An in vitro model of human hematopoiesis identifies a regulatory role for the aryl hydrocarbon receptor von Khan, D M Isha Olive, Karmaus, Peer W. F., Bach, Anthony, Crawford, Robert B., Kaminski, Norbert E.

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