An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction von Hanke, Leo, Vidakovics Perez, Laura, Sheward, Daniel J., Das, Hrishikesh, Schulte, Tim, Moliner-Morro, Ainhoa, Corcoran, Martin, Achour, Adnane, Karlsson Hedestam, Gunilla B., Hällberg, B. Martin, Murrell, Ben, McInerney, Gerald M.

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Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity von Corcoran, Martin M., Phad, Ganesh E., Bernat, Néstor Vázquez, Stahl-Hennig, Christiane, Sumida, Noriyuki, Persson, Mats A.A., Martin, Marcel, Hedestam, Gunilla B. Karlsson

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Route of Vaccine Administration Alters Antigen Trafficking but Not Innate or Adaptive Immunity von Ols, Sebastian, Yang, Lifei, Thompson, Elizabeth A., Pushparaj, Pradeepa, Tran, Karen, Liang, Frank, Lin, Ang, Eriksson, Bengt, Karlsson Hedestam, Gunilla B., Wyatt, Richard T., Loré, Karin

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Interleukin-21-Producing CD4+ T Cells Promote Type 2 Immunity to House Dust Mites von Coquet, Jonathan M., Schuijs, Martijn J., Smyth, Mark J., Deswarte, Kim, Beyaert, Rudi, Braun, Harald, Boon, Louis, Hedestam, Gunilla B. Karlsson, Nutt, Steven L., Hammad, Hamida, Lambrecht, Bart N.

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MAVS, cGAS, and endogenous retroviruses in T-independent B cell responses von Zeng, Ming, Hu, Zeping, Shi, Xiaolei, Li, Xiaohong, Zhan, Xiaoming, Li, Xiao-Dong, Wang, Jianhui, Choi, Jin Huk, Wang, Kuan-wen, Purrington, Tiana, Tang, Miao, Fina, Maggy, DeBerardinis, Ralph J., Moresco, Eva Marie Y., Pedersen, Gabriel, McInerney, Gerald M., Hedestam, Gunilla B. Karlsson, Chen, Zhijian J., Beutler, Bruce

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Sensitivity of the SARS-CoV-2 BA.2.86 variant to prevailing neutralising antibody responses von Sheward, Daniel J, Yang, Yiqiu, Westerberg, Michelle, Öling, Sofia, Muschiol, Sandra, Sato, Kenta, Peacock, Thomas P, Karlsson Hedestam, Gunilla B, Albert, Jan, Murrell, Ben

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Unmodified rabies mRNA vaccine elicits high cross-neutralizing antibody titers and diverse B cell memory responses von Hellgren, Fredrika, Cagigi, Alberto, Arcoverde Cerveira, Rodrigo, Ols, Sebastian, Kern, Theresa, Lin, Ang, Eriksson, Bengt, Dodds, Michael G., Jasny, Edith, Schwendt, Kim, Freuling, Conrad, Müller, Thomas, Corcoran, Martin, Karlsson Hedestam, Gunilla B., Petsch, Benjamin, Loré, Karin

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Targeted N-glycan deletion at the receptor-binding site retains HIV Env NFL trimer integrity and accelerates the elicited antibody response von Dubrovskaya, Viktoriya, Guenaga, Javier, de Val, Natalia, Wilson, Richard, Feng, Yu, Movsesyan, Arlette, Karlsson Hedestam, Gunilla B, Ward, Andrew B, Wyatt, Richard T

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Vaccination induces HIV broadly neutralizing antibody precursors in humans von Leggat, David J, Cohen, Kristen W, Willis, Jordan R, Fulp, William J, deCamp, Allan C, Kalyuzhniy, Oleksandr, Cottrell, Christopher A, Menis, Sergey, Finak, Greg, Ballweber-Fleming, Lamar, Srikanth, Abhinaya, Plyler, Jason R, Schiffner, Torben, Liguori, Alessia, Rahaman, Farhad, Lombardo, Angela, Philiponis, Vincent, Whaley, Rachael E, Seese, Aaron, Brand, Joshua, Ruppel, Alexis M, Hoyland, Wesley, Yates, Nicole L, Williams, LaTonya D, Greene, Kelli, Gao, Hongmei, Mahoney, Celia R, Corcoran, Martin M, Cagigi, Alberto, Taylor, Alison, Brown, David M, Ambrozak, David R, Sincomb, Troy, Hu, Xiaozhen, Tingle, Ryan, Georgeson, Erik, Eskandarzadeh, Saman, Alavi, Nushin, Lu, Danny, Mullen, Tina-Marie, Kubitz, Michael, Groschel, Bettina, Maenza, Janine, Kolokythas, Orpheus, Khati, Nadia, Bethony, Jeffrey, Crotty, Shane, Roederer, Mario, Karlsson Hedestam, Gunilla B, Tomaras, Georgia D, Montefiori, David, Diemert, David, Koup, Richard A, Laufer, Dagna S, McElrath, M Juliana, McDermott, Adrian B, Schief, William R

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VDJ Gene Usage in IgM Repertoires of Rhesus and Cynomolgus Macaques von Chernyshev, Mark, Kaduk, Mateusz, Corcoran, Martin, Karlsson Hedestam, Gunilla B

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Addressing IGHV Gene Structural Diversity Enhances Immunoglobulin Repertoire Analysis: Lessons From Rhesus Macaque von Kaduk, Mateusz, Corcoran, Martin, Karlsson Hedestam, Gunilla B

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Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization von Aljedani, Safia S, Liban, Tyler J, Tran, Karen, Phad, Ganesh, Singh, Suruchi, Dubrovskaya, Viktoriya, Pushparaj, Pradeepa, Martinez-Murillo, Paola, Rodarte, Justas, Mileant, Alex, Mangala Prasad, Vidya, Kinzelman, Rachel, O'Dell, Sijy, Mascola, John R, Lee, Kelly K, Karlsson Hedestam, Gunilla B, Wyatt, Richard T, Pancera, Marie

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Neutralisation sensitivity of the SARS-CoV-2 omicron (B.1.1.529) variant: a cross-sectional study von Sheward, Daniel J, Kim, Changil, Ehling, Roy A, Pankow, Alec, Castro Dopico, Xaquin, Dyrdak, Robert, Martin, Darren P, Reddy, Sai T, Dillner, Joakim, Karlsson Hedestam, Gunilla B, Albert, Jan, Murrell, Ben

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Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign von Tran, Karen, Poulsen, Christian, Guenaga, Javier, de Val, Natalia, de Val Alda, Natalia, Wilson, Richard, Sundling, Christopher, Li, Yuxing, Stanfield, Robyn L, Wilson, Ian A, Ward, Andrew B, Karlsson Hedestam, Gunilla B, Wyatt, Richard T

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Rhesus and cynomolgus macaque immunoglobulin heavy-chain genotyping yields comprehensive databases of germline VDJ alleles von Vázquez Bernat, Néstor, Corcoran, Martin, Nowak, Izabela, Kaduk, Mateusz, Castro Dopico, Xaquin, Narang, Sanjana, Maisonasse, Pauline, Dereuddre-Bosquet, Nathalie, Murrell, Ben, Karlsson Hedestam, Gunilla B.

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High-Quality Library Preparation for NGS-Based Immunoglobulin Germline Gene Inference and Repertoire Expression Analysis von Vázquez Bernat, Néstor, Corcoran, Martin, Hardt, Uta, Kaduk, Mateusz, Phad, Ganesh E, Martin, Marcel, Karlsson Hedestam, Gunilla B

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Integrated single cell and spatial transcriptomics reveal autoreactive differentiated B cells in joints of early rheumatoid arthritis von Hardt, Uta, Carlberg, Konstantin, af Klint, Erik, Sahlström, Peter, Larsson, Ludvig, van Vollenhoven, Annika, Hernandez Machado, Susana, Israelsson, Lena, Amara, Khaled, Chemin, Karine, Korotkova, Marina, Karlsson Hedestam, Gunilla B., Catrina, Anca I., Teichmann, Sarah A., Ståhl, Patrik L., Malmström, Vivianne

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The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus von Karlsson Hedestam, Gunilla B., Fouchier, Ron A.M., Phogat, Sanjay, Burton, Dennis R., Sodroski, Joseph, Wyatt, Richard T.

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forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity von Arnold, Carrie N, Pirie, Elaine, Dosenovic, Pia, McInerney, Gerald M, Xia, Yu, Wang, Nathaniel, Li, Xiaohong, Siggs, Owen M, Karlsson Hedestam, Gunilla B, Beutler, Bruce

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Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability von Dubrovskaya, Viktoriya, Tran, Karen, Ozorowski, Gabriel, Guenaga, Javier, Wilson, Richard, Bale, Shridhar, Cottrell, Christopher A., Turner, Hannah L., Seabright, Gemma, O’Dell, Sijy, Torres, Jonathan L., Yang, Lifei, Feng, Yu, Leaman, Daniel P., Vázquez Bernat, Néstor, Liban, Tyler, Louder, Mark, McKee, Krisha, Bailer, Robert T., Movsesyan, Arlette, Doria-Rose, Nicole A., Pancera, Marie, Karlsson Hedestam, Gunilla B., Zwick, Michael B., Crispin, Max, Mascola, John R., Ward, Andrew B., Wyatt, Richard T.

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