Glial Activation and Glucose Metabolism in a Transgenic Amyloid Mouse Model: A Triple-Tracer PET Study von Brendel, Matthias, Probst, Federico, Jaworska, Anna, Overhoff, Felix, Korzhova, Viktoria, Albert, Nathalie L, Beck, Roswitha, Lindner, Simon, Gildehaus, Franz-Josef, Baumann, Karlheinz, Bartenstein, Peter, Kleinberger, Gernot, Haass, Christian, Herms, Jochen, Rominger, Axel

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Path mediation analysis reveals GBA impacts Lewy body disease status by increasing α-synuclein levels von Gündner, Anna Lisa, Duran-Pacheco, Gonzalo, Zimmermann, Silke, Ruf, Iris, Moors, Tim, Baumann, Karlheinz, Jagasia, Ravi, van de Berg, Wilma D.J., Kremer, Thomas

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Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo μPET-study von Blume, Tanja, Focke, Carola, Peters, Finn, Deussing, Maximilian, Albert, Nathalie L, Lindner, Simon, Gildehaus, Franz-Josef, von Ungern-Sternberg, Barbara, Ozmen, Laurence, Baumann, Karlheinz, Bartenstein, Peter, Rominger, Axel, Herms, Jochen, Brendel, Matthias

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Cross-sectional comparison of small animal [18F]-florbetaben amyloid-PET between transgenic AD mouse models von Brendel, Matthias, Jaworska, Anna, Grießinger, Eric, Rötzer, Christina, Burgold, Steffen, Gildehaus, Franz-Josef, Carlsen, Janette, Cumming, Paul, Baumann, Karlheinz, Haass, Christian, Steiner, Harald, Bartenstein, Peter, Herms, Jochen, Rominger, Axel

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Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition von Blume, Tanja, Deussing, Maximilian, Biechele, Gloria, Peters, Finn, Zott, Benedikt, Schmidt, Claudio, Franzmeier, Nicolai, Wind, Karin, Eckenweber, Florian, Sacher, Christian, Shi, Yuan, Ochs, Katharina, Kleinberger, Gernot, Xiang, Xianyuan, Focke, Carola, Lindner, Simon, Gildehaus, Franz-Josef, Beyer, Leonie, von Ungern-Sternberg, Barbara, Bartenstein, Peter, Baumann, Karlheinz, Adelsberger, Helmuth, Rominger, Axel, Cumming, Paul, Willem, Michael, Dorostkar, Mario M, Herms, Jochen, Brendel, Matthias

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Assessment of synaptic loss in mouse models of β-amyloid and tau pathology using [18F]UCB-H PET imaging von Vogler, Letizia, Ballweg, Anna, Bohr, Bernd, Briel, Nils, Wind, Karin, Antons, Melissa, Kunze, Lea H., Gnörich, Johannes, Lindner, Simon, Gildehaus, Franz-Josef, Baumann, Karlheinz, Bartenstein, Peter, Boening, Guido, Ziegler, Sibylle I., Levin, Johannes, Zwergal, Andreas, Höglinger, Günter U., Herms, Jochen, Brendel, Matthias

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Generation of a homozygous GBA deletion human embryonic stem cell line von Gündner, Anna Lisa, Meyer, Claas Aiko, Aigner, Stefan, Christensen, Klaus, Patsch, Christoph, Jagasia, Ravi, Baumann, Karlheinz, Burcin, Mark

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Potent and Selective BACE-1 Peptide Inhibitors Lower Brain Aβ Levels Mediated by Brain Shuttle Transport von Ruderisch, Nadine, Schlatter, Daniel, Kuglstatter, Andreas, Guba, Wolfgang, Huber, Sylwia, Cusulin, Carlo, Benz, Jörg, Rufer, Arne Christian, Hoernschemeyer, Joerg, Schweitzer, Christophe, Bülau, Tina, Gärtner, Achim, Hoffmann, Eike, Niewoehner, Jens, Patsch, Christoph, Baumann, Karlheinz, Loetscher, Hansruedi, Kitas, Eric, Freskgård, Per-Ola

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The endogenous and cell cycle-dependent phosphorylation of tau protein in living cells: implications for Alzheimer's disease von Illenberger, S, Zheng-Fischhöfer, Q, Preuss, U, Stamer, K, Baumann, K, Trinczek, B, Biernat, J, Godemann, R, Mandelkow, E M, Mandelkow, E

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Data on specificity of [18F]GE180 uptake for TSPO expression in rodent brain and myocardium von Deussing, Maximilian, Blume, Tanja, Vomacka, Lena, Mahler, Christoph, Focke, Carola, Todica, Andrei, Unterrainer, Marcus, Albert, Nathalie L., Lindner, Simon, von Ungern-Sternberg, Barbara, Baumann, Karlheinz, Zwergal, Andreas, Bartenstein, Peter, Herms, Jochen, Rominger, Axel, Brendel, Matthias

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Curcumin Derivatives Inhibit or Modulate Beta-Amyloid Precursor Protein Metabolism von Narlawar, Rajeshwar, Baumann, Karlheinz, Schubenel, Robert, Schmidt, Boris

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Alzheimer's disease-like neuropathology of gene-targeted APP-SLxPS1mut mice expressing the amyloid precursor protein at endogenous levels von Köhler, Christoph, Ebert, Ulrich, Baumann, Karlheinz, Schröder, Hannsjörg

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Aβ43‐producing PS1 FAD mutants cause altered substrate interactions and respond to γ‐secretase modulation von Trambauer, Johannes, Rodríguez Sarmiento, Rosa María, Fukumori, Akio, Feederle, Regina, Baumann, Karlheinz, Steiner, Harald

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Novel γ-Secretase Enzyme Modulators Directly Target Presenilin Protein von Ebke, Amelie, Luebbers, Thomas, Fukumori, Akio, Shirotani, Keiro, Haass, Christian, Baumann, Karlheinz, Steiner, Harald

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Gamma secretase modulators and BACE inhibitors reduce Aβ production without altering gene expression in Alzheimer's disease iPSC-derived neurons and mice von Cusulin, Carlo, Wells, Isabelle, Badillo, Solveig, Duran-Pacheco, Gonzalo Christian, Baumann, Karlheinz, Patsch, Christoph

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Stepwise Design of γ‑Secretase Modulators with an Advanced Profile by Judicious Coordinated Structural Replacements and an Unconventional Phenyl Ring Bioisostere von Rodríguez Sarmiento, Rosa María, Bissantz, Caterina, Bylund, Johan, Limberg, Anja, Neidhart, Werner, Jakob-Roetne, Roland, Wang, Lisha, Baumann, Karlheinz

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Aβ43‐producing PS 1 FAD mutants cause altered substrate interactions and respond to γ‐secretase modulation von Trambauer, Johannes, Rodríguez Sarmiento, Rosa María, Fukumori, Akio, Feederle, Regina, Baumann, Karlheinz, Steiner, Harald

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Early and Longitudinal Microglial Activation but Not Amyloid Accumulation Predicts Cognitive Outcome in PS2APP Mice von Focke, Carola, Blume, Tanja, Zott, Benedikt, Shi, Yuan, Deussing, Maximilian, Peters, Finn, Schmidt, Claudio, Kleinberger, Gernot, Lindner, Simon, Gildehaus, Franz-Josef, Beyer, Leonie, von Ungern-Sternberg, Barbara, Bartenstein, Peter, Ozmen, Laurence, Baumann, Karlheinz, Dorostkar, Mario M, Haass, Christian, Adelsberger, Helmuth, Herms, Jochen, Rominger, Axel, Brendel, Matthias

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Asymmetry of Fibrillar Plaque Burden in Amyloid Mouse Models von Sacher, Christian, Blume, Tanja, Beyer, Leonie, Biechele, Gloria, Sauerbeck, Julia, Eckenweber, Florian, Deussing, Maximilian, Focke, Carola, Parhizkar, Samira, Lindner, Simon, Gildehaus, Franz-Josef, von Ungern-Sternberg, Barbara, Baumann, Karlheinz, Tahirovic, Sabina, Kleinberger, Gernot, Willem, Michael, Haass, Christian, Bartenstein, Peter, Cumming, Paul, Rominger, Axel, Herms, Jochen, Brendel, Matthias

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Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo [mu]PET-study von Blume, Tanja, Focke, Carola, Peters, Finn, Deussing, Maximilian, Albert, Nathalie L, Lindner, Simon, Gildehaus, Franz-Josef, von Ungern-Sternberg, Barbara, Ozmen, Laurence, Baumann, Karlheinz, Bartenstein, Peter, Rominger, Axel, Herms, Jochen, Brendel, Matthias

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