The global preclinical antibacterial pipeline von Theuretzbacher, Ursula, Outterson, Kevin, Engel, Aleks, Karlén, Anders

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Docking of Macrocycles: Comparing Rigid and Flexible Docking in Glide von Alogheli, Hiba, Olanders, Gustav, Schaal, Wesley, Brandt, Peter, Karlén, Anders

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Conformational analysis of macrocycles: comparing general and specialized methods von Olanders, Gustav, Alogheli, Hiba, Brandt, Peter, Karlén, Anders

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Discovery and preclinical development of new antibiotics von Hughes, Diarmaid, Karlén, Anders

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Virtual Screening Data Fusion Using Both Structure- and Ligand-Based Methods von Svensson, Fredrik, Karlén, Anders, Sköld, Christian

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Predicting the Rate of Skin Penetration Using an Aggregated Conformal Prediction Framework von Lindh, Martin, Karlén, Anders, Norinder, Ulf

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Computational studies of molecular pre-organization through macrocyclization: Conformational distribution analysis of closely related non-macrocyclic and macrocyclic analogs von Olanders, Gustav, Brandt, Peter, Sköld, Christian, Karlén, Anders

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ENABLE: an engine for European antibacterial drug discovery and development von Olliver, Marie, Griestop, Laura, Hughes, Diarmaid, Belfrage, Anna Karin, Gising, Johan, Baranczewski, Pawel, Vingsbo Lundberg, Carina, Karlén, Anders

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Virtual screening and bioassay study of novel inhibitors for dengue virus mRNA cap (nucleoside-2′ O)-methyltransferase von Luzhkov, Victor B., Selisko, Barbara, Nordqvist, Anneli, Peyrane, Frédéric, Decroly, Etienne, Alvarez, Karine, Karlen, Anders, Canard, Bruno, Åqvist, Johan

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Antibacterial sulfonimidamide-based oligopeptides as type I signal peptidase inhibitors: Synthesis and biological evaluation von Benediktsdottir, Andrea, Lu, Lu, Cao, Sha, Zamaratski, Edouard, Karlén, Anders, Mowbray, Sherry L., Hughes, Diarmaid, Sandström, Anja

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Bacterial type I signal peptidase inhibitors - Optimized hits from nature von Szałaj, Natalia, Benediktsdottir, Andrea, Rusin, Dominika, Karlén, Anders, Mowbray, Sherry L., Więckowska, Anna

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Design, Synthesis, and Biological Evaluation of the First Selective Nonpeptide AT2 Receptor Agonist von Wan, Yiqian, Wallinder, Charlotta, Plouffe, Bianca, Beaudry, Hélène, Mahalingam, A. K, Wu, Xiongyu, Johansson, Berndt, Holm, Mathias, Botoros, Milad, Karlén, Anders, Pettersson, Anders, Nyberg, Fred, Fändriks, Lars, Gallo-Payet, Nicole, Hallberg, Anders, Alterman, Mathias

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Potent Macrocyclic Inhibitors of Insulin-Regulated Aminopeptidase (IRAP) by Olefin Ring-Closing Metathesis von Andersson, Hanna, Demaegdt, Heidi, Johnsson, Anders, Vauquelin, Georges, Lindeberg, Gunnar, Hallberg, Mathias, Erdélyi, Máté, Karlén, Anders, Hallberg, Anders

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Design, synthesis, and in vitro biological evaluation of meta-sulfonamidobenzamide-based antibacterial LpxH inhibitors von Benediktsdottir, Andrea, Sooriyaarachchi, Sanjeewani, Cao, Sha, Ottosson, Nina E., Lindström, Stefan, Lundgren, Bo, Kloditz, Katharina, Lola, Daina, Bobileva, Olga, Loza, Einars, Hughes, Diarmaid, Jones, T. Alwyn, Mowbray, Sherry L., Zamaratski, Edouard, Sandström, Anja, Karlén, Anders

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Trisubstituted Imidazoles as Mycobacterium tuberculosis Glutamine Synthetase Inhibitors von Gising, Johan, Nilsson, Mikael T, Odell, Luke R, Yahiaoui, Samir, Lindh, Martin, Iyer, Harini, Sinha, Achyut M, Srinivasa, Bachally R, Larhed, Mats, Mowbray, Sherry L, Karlén, Anders

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Disulfide Cyclized Tripeptide Analogues of Angiotensin IV as Potent and Selective Inhibitors of Insulin-Regulated Aminopeptidase (IRAP) von Andersson, Hanna, Demaegdt, Heidi, Vauquelin, Georges, Lindeberg, Gunnar, Karlén, Anders, Hallberg, Mathias, Erdélyi, Máté, Hallberg, Anders

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Achiral Pyrazinone-Based Inhibitors of the Hepatitis C Virus NS3 Protease and Drug-Resistant Variants with Elongated Substituents Directed Toward the S2 Pocket von Gising, Johan, Belfrage, Anna Karin, Alogheli, Hiba, Ehrenberg, Angelica, Åkerblom, Eva, Svensson, Richard, Artursson, Per, Karlén, Anders, Danielson, U. Helena, Larhed, Mats, Sandström, Anja

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Toward a Benchmarking Data Set Able to Evaluate Ligand- and Structure-based Virtual Screening Using Public HTS Data von Lindh, Martin, Svensson, Fredrik, Schaal, Wesley, Zhang, Jin, Sköld, Christian, Brandt, Peter, Karlén, Anders

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Synthesis of Functionalized Cinnamaldehyde Derivatives by an Oxidative Heck Reaction and Their Use as Starting Materials for Preparation of Mycobacterium tuberculosis 1-Deoxy-d-xyl... von Nordqvist, Anneli, Björkelid, Christofer, Andaloussi, Mounir, Jansson, Anna M, Mowbray, Sherry L, Karlén, Anders, Larhed, Mats

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Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria von Huseby, Douglas L, Cao, Sha, Zamaratski, Edouard, Sooriyaarachchi, Sanjeewani, Ahmad, Shabbir, Bergfors, Terese, Krasnova, Laura, Pelss, Juris, Ikaunieks, Martins, Loza, Einars, Katkevics, Martins, Bobileva, Olga, Cirule, Helena, Gukalova, Baiba, Grinberga, Solveiga, Backlund, Maria, Simoff, Ivailo, Leber, Anna T, Berruga-Fernández, Talía, Antonov, Dmitry, Konda, Vivekananda R, Lindström, Stefan, Olanders, Gustav, Brandt, Peter, Baranczewski, Pawel, Vingsbo Lundberg, Carina, Liepinsh, Edgars, Suna, Edgars, Jones, T Alwyn, Mowbray, Sherry L, Hughes, Diarmaid, Karlén, Anders

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