An Inhibitor of Nonhomologous End-Joining Abrogates Double-Strand Break Repair and Impedes Cancer Progression von Srivastava, Mrinal, Nambiar, Mridula, Sharma, Sheetal, Karki, Subhas S., Goldsmith, G., Hegde, Mahesh, Kumar, Sujeet, Pandey, Monica, Singh, Ram K., Ray, Pritha, Natarajan, Renuka, Kelkar, Madhura, De, Abhijit, Choudhary, Bibha, Raghavan, Sathees C.

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ST09, A Novel Curcumin Derivative, Blocks Cell Migration by Inhibiting Matrix Metalloproteases in Breast Cancer Cells and Inhibits Tumor Progression in EAC Mouse Tumor Models von Nirgude, Snehal, Mahadeva, Raghunandan, Koroth, Jinsha, Kumar, Sujeet, Kumar, Kothanahally S Sharath, Gopalakrishnan, Vidya, S Karki, Subhas S, Choudhary, Bibha

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A Coumarin-Imidazothiadiazole Derivative, SP11 Abrogates Tumor Growth by Targeting HSP90 and Its Client Proteins von Nirgude, Snehal, Shahana M V, Ravindran, Febina, Kumar, Sujeet, Sharma, Shivangi, Mahadeva, Raghunandan, Mhatre, Anisha, Karki, Subhas S, Choudhary, Bibha

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A Novel Resveratrol Based Tubulin Inhibitor Induces Mitotic Arrest and Activates Apoptosis in Cancer Cells von Thomas, Elizabeth, Gopalakrishnan, Vidya, Hegde, Mahesh, Kumar, Sujeet, Karki, Subhas S., Raghavan, Sathees C., Choudhary, Bibha

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Novel levamisole derivative induces extrinsic pathway of apoptosis in cancer cells and inhibits tumor progression in mice von Hegde, Mahesh, Karki, Subhas S, Thomas, Elizabeth, Kumar, Sujeet, Panjamurthy, Kuppusamy, Ranganatha, Somasagara R, Rangappa, Kanchugarakoppal S, Choudhary, Bibha, Raghavan, Sathees C

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Effects of green synthesised silver nanoparticles (ST06-AgNPs) using curcumin derivative (ST06) on human cervical cancer cells (HeLa) in vitro and EAC tumor bearing mice models von Murugesan, Kalaimathi, Koroth, Jinsha, Srinivasan, Padma Priya, Singh, Amrita, Mukundan, Sanjana, Karki, Subhas S, Choudhary, Bibha, Gupta, Chhitar M

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Synthesis of Novel Pyrazole-Oxindole Conjugates with Cytotoxicity in Human Cancer Cells via Apoptosis von Jain, Pravesh M, Gutierrez, Denisse A, Kumar, Sujeet, Aguilera, Renato J, Karki, Subhas S

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Pluronic copolymer encapsulated SCR7 as a potential anticancer agent von John, Franklin, George, Jinu, Srivastava, Mrinal, Hassan, P. A, Aswal, V. K, Karki, Subhas. S, Raghavan, Sathees. C

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Curcumin derivative 1, 2-bis [(3E, 5E)-3, 5-bis [(2-chlorophenyl) methylene]-4-oxo-1-piperidyl] ethane-1, 2-dione (ST03) induces mitochondria mediated apoptosis in ovarian cancer c... von Koroth, Jinsha, Mahadeva, Raghunandan, Ravindran, Febina, Parashar, Tanvi R, Teja, Vinay, Karki, Subhas S, Choudhary, Bibha

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Autocyclized and oxidized forms of SCR7 induce cancer cell death by inhibiting nonhomologous DNA end joining in a Ligase IV dependent manner von Vartak, Supriya V., Swarup, Hassan A., Gopalakrishnan, Vidya, Gopinatha, Vindya K., Ropars, Virginie, Nambiar, Mridula, John, Franklin, Kothanahally, Sharath Kumar S., Kumari, Rupa, Kumari, Nitu, Ray, Ujjayinee, Radha, Gudapureddy, Dinesh, Depina, Pandey, Monica, Ananda, Hanumappa, Karki, Subhas S., Srivastava, Mrinal, Charbonnier, Jean Baptiste, Choudhary, Bibha, Mantelingu, Kempegowda, Raghavan, Sathees C.

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Synthesis, in vitro cytotoxicity, molecular docking and ADME study of some indolin-2-one linked 1,2,3-triazole derivatives von Das, Arnika, Greco, Giulia, Kumar, Sujeet, Catanzaro, Elena, Morigi, Rita, Locatelli, Alessandra, Schols, Dominique, Alici, Hakan, Tahtaci, Hakan, Ravindran, Febina, Fimognari, Carmela, Karki, Subhas S.

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Enhanced Efficacy of Pluronic Copolymer Micelle Encapsulated SCR7 against Cancer Cell Proliferation von John, Franklin, George, Jinu, Vartak, Supriya V., Srivastava, Mrinal, Hassan, P. A., Aswal, V. K., Karki, Subhas. S., Raghavan, Sathees C.

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Three novel piperidones exhibit tumor-selective cytotoxicity on leukemia cells via protein degradation and stress-mediated mechanisms von Contreras, Lisett, Medina, Stephanie, Schiaffino Bustamante, Austre Y., Borrego, Edgar A., Valenzuela, Carlos A., Das, Umashankar, Karki, Subhas S., Dimmock, Jonathan R., Aguilera, Renato J.

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Synthesis and biological evaluation of novel 2-aralkyl-5-substituted-6-(4′-fluorophenyl)-imidazo[2,1-b][1,3,4]thiadiazole derivatives as potent anticancer agents von Karki, Subhas S., Panjamurthy, Kuppusamy, Kumar, Sujeet, Nambiar, Mridula, Ramareddy, Sureshbabu A., Chiruvella, Kishore K., Raghavan, Sathees C.

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Novel BCL2 inhibitor, Disarib induces apoptosis by disruption of BCL2-BAK interaction von Vartak, Supriya V., Iyer, Divyaanka, Santhoshkumar, T.R., Sharma, Sheetal, Mishra, Archita, Goldsmith, Gunaseelan, Srivastava, Mrinal, Srivastava, Shikha, Karki, Subhas S., Surolia, Avadhesha, Choudhary, Bibha, Raghavan, Sathees C.

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3,5-Bis(3-dimethylaminomethyl-4-hydroxybenzylidene)-4-piperidone and related compounds induce glutathione oxidation and mitochondria-mediated cell death in HCT-116 colon cancer cel... von Addala, Eshwari, Rafiei, Hossein, Das, Swagatika, Bandy, Brian, Das, Umashankar, Karki, Subhas S., Dimmock, Jonathan R.

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Synthesis, characterization, and biological evaluation of some 4-((thiophen-2-yl-methylene)amino)benzenesulfonamide metal complexes von Sekhar, E. Vijaya, Karki, Subhas S., Rangaswamy, Javarappa, Bhat, Mahesh, Kumar, Sujeet

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A novel inhibitor of BCL2, Disarib abrogates tumor growth while sparing platelets, by activating intrinsic pathway of apoptosis von Vartak, Supriya V., Hegde, Mahesh, Iyer, Divyaanka, Gaikwad, Snehal, Gopalakrishnan, Vidya, Srivastava, Mrinal, Karki, Subhas S., Choudhary, Bibha, Ray, Pritha, Santhoshkumar, T.R., Raghavan, Sathees C.

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Identification of a novel BCL2‐specific inhibitor that binds predominantly to the BH1 domain von Iyer, Divyaanka, Vartak, Supriya V., Mishra, Archita, Goldsmith, Gunaseelan, Kumar, Sujeet, Srivastava, Mrinal, Hegde, Mahesh, Gopalakrishnan, Vidya, Glenn, Mark, Velusamy, Mahesh, Choudhary, Bibha, Kalakonda, Nagesh, Karki, Subhas S., Surolia, Avadhesha, Raghavan, Sathees C.

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Identification and characterization of novel ligase I inhibitors von Pandey, Monica, Kumar, Sujeet, Goldsmith, Gunaseelan, Srivastava, Mrinal, Elango, Santhini, Shameem, Mohammad, Bannerjee, Dibyendu, Choudhary, Bibha, Karki, Subhas S., Raghavan, Sathees C.

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